AU2005215213C1 - Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds - Google Patents

Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds Download PDF

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Publication number
AU2005215213C1
AU2005215213C1 AU2005215213A AU2005215213A AU2005215213C1 AU 2005215213 C1 AU2005215213 C1 AU 2005215213C1 AU 2005215213 A AU2005215213 A AU 2005215213A AU 2005215213 A AU2005215213 A AU 2005215213A AU 2005215213 C1 AU2005215213 C1 AU 2005215213C1
Authority
AU
Australia
Prior art keywords
composition
cells
matrix
wound healing
fibrin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2005215213A
Other languages
English (en)
Other versions
AU2005215213B2 (en
AU2005215213A1 (en
Inventor
Margaret Batten
Penelope Ann Johnson
Paul Kemp
Michael Mcwhan
Andrew Shering
Jennifer Sutherland
Gyorgyi Talas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith and Nephew Orthopaedics AG
Original Assignee
Smith and Nephew Orthopaedics AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0403220A external-priority patent/GB0403220D0/en
Priority claimed from GB0403226A external-priority patent/GB0403226D0/en
Priority claimed from GB0426252A external-priority patent/GB0426252D0/en
Application filed by Smith and Nephew Orthopaedics AG filed Critical Smith and Nephew Orthopaedics AG
Publication of AU2005215213A1 publication Critical patent/AU2005215213A1/en
Assigned to DFB TECHNOLOGY HOLDINGS, LLC reassignment DFB TECHNOLOGY HOLDINGS, LLC Request for Assignment Assignors: INTERCYTEX LIMITED
Application granted granted Critical
Publication of AU2005215213B2 publication Critical patent/AU2005215213B2/en
Publication of AU2005215213C1 publication Critical patent/AU2005215213C1/en
Assigned to SMITH & NEPHEW ORTHOPAEDICS AG reassignment SMITH & NEPHEW ORTHOPAEDICS AG Request for Assignment Assignors: DFB TECHNOLOGY HOLDINGS, LLC
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33Fibroblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/34Muscles; Smooth muscle cells; Heart; Cardiac stem cells; Myoblasts; Myocytes; Cardiomyocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3895Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells using specific culture conditions, e.g. stimulating differentiation of stem cells, pulsatile flow conditions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/60Materials for use in artificial skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Botany (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
AU2005215213A 2004-02-13 2005-02-14 Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds Ceased AU2005215213C1 (en)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB0403220A GB0403220D0 (en) 2004-02-13 2004-02-13 Wound healing composition
GB0403220.7 2004-02-13
GB0403226.4 2004-02-13
GB0403226A GB0403226D0 (en) 2004-02-13 2004-02-13 Means of packaging a wound healing composition
US55619404P 2004-03-25 2004-03-25
US55615504P 2004-03-25 2004-03-25
US60/556,194 2004-03-25
US60/556,155 2004-03-25
GB0426252.3 2004-11-30
GB0426252A GB0426252D0 (en) 2004-11-30 2004-11-30 Wound healing composition
US63242504P 2004-12-01 2004-12-01
US60/632,425 2004-12-01
PCT/GB2005/000523 WO2005079822A2 (en) 2004-02-13 2005-02-14 Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds

Publications (3)

Publication Number Publication Date
AU2005215213A1 AU2005215213A1 (en) 2005-09-01
AU2005215213B2 AU2005215213B2 (en) 2010-09-09
AU2005215213C1 true AU2005215213C1 (en) 2011-04-28

Family

ID=34891423

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2005215213A Ceased AU2005215213C1 (en) 2004-02-13 2005-02-14 Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds
AU2005215211A Ceased AU2005215211B2 (en) 2004-02-13 2005-02-14 Wound healing profile

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2005215211A Ceased AU2005215211B2 (en) 2004-02-13 2005-02-14 Wound healing profile

Country Status (6)

Country Link
US (3) US8765169B2 (enExample)
EP (2) EP1718317A1 (enExample)
JP (4) JP5706058B2 (enExample)
AU (2) AU2005215213C1 (enExample)
CA (2) CA2555233A1 (enExample)
WO (2) WO2005079821A1 (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0224986D0 (en) 2002-10-28 2002-12-04 Smith & Nephew Apparatus
US8779053B2 (en) 2003-08-25 2014-07-15 Dow Global Technologies Llc Coating compositions
US8722787B2 (en) 2003-08-25 2014-05-13 Dow Global Technologies Llc Coating composition and articles made therefrom
US9169406B2 (en) 2003-08-25 2015-10-27 Dow Global Technologies Llc Coating compositions
US8946329B2 (en) 2003-08-25 2015-02-03 Dow Global Technologies Llc Coating compositions
US11298453B2 (en) 2003-10-28 2022-04-12 Smith & Nephew Plc Apparatus and method for wound cleansing with actives
AU2005215213C1 (en) 2004-02-13 2011-04-28 Smith & Nephew Orthopaedics Ag Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds
GB0508531D0 (en) 2005-04-27 2005-06-01 Smith & Nephew Sai with ultrasound
US7753894B2 (en) 2004-04-27 2010-07-13 Smith & Nephew Plc Wound cleansing apparatus with stress
GB0409446D0 (en) 2004-04-28 2004-06-02 Smith & Nephew Apparatus
CN100402097C (zh) * 2006-07-24 2008-07-16 暨南大学 琼脂/胶原皮肤创伤修复敷料及其制备方法和应用
FR2917629B1 (fr) * 2007-06-22 2009-09-11 Oreal Utilisation cosmetique de proteines de type apolipoproteine d
WO2009045543A1 (en) * 2007-10-04 2009-04-09 The Regents Of The University Of California Treatment of conditions related to shock
GB2457870A (en) 2007-12-21 2009-09-02 Intercytex Ltd Wound Dressing Applicator
US8580314B2 (en) * 2008-11-04 2013-11-12 Stratatech Corporation Dried and irradiated skin equivalents for ready use
WO2011023843A2 (es) * 2009-08-25 2011-03-03 Servicio Andaluz De Salud Elaboración de tejidos artificiales mediante ingeniería tisular utilizando biomateriales de fibrina y agarosa
EP2621521A4 (en) 2010-10-02 2014-04-23 Univ California MINIMIZING DARMDYS FUNCTIONS
WO2012085298A1 (es) * 2010-12-22 2012-06-28 Universidad De Valladolid (40%) Gel de fibrina que contiene células del limbo esclerocorneal y su uso en bioingeniería de la superficie ocular
FR2999083B1 (fr) * 2012-12-12 2015-01-23 Univ Nantes Pansement contenant des fibroblastes et des keratinocytes foetaux
CN110551424B (zh) 2012-12-28 2022-07-29 陶氏环球技术有限责任公司 涂料组合物和由其制成的物品
BR112015015408B1 (pt) 2012-12-28 2021-07-20 Dow Global Technologies Llc Composição de revestimento, e, artigo revestido
RU2015152082A (ru) 2013-05-10 2017-06-16 СМИТ ЭНД НЕФЬЮ ПиЭлСи Соединитель для текучей среды для орошения и аспирации ран
US20160213714A1 (en) * 2015-01-23 2016-07-28 Everon Biosciences, Inc. Induction of cellular senescence for tissue therapies
GB201504124D0 (en) 2015-03-11 2015-04-22 Proqr Therapeutics B V Oligonucleotides
RU2657202C1 (ru) * 2017-06-13 2018-06-08 Государственное бюджетное учреждение здравоохранения "Научно-исследовательский институт - краевая клиническая больница имени профессора С.В. Очаповского" Министерства Здравоохранения Краснодарского края (ГБУЗ "НИИ-ККБ N 1 им. проф. Очаповского" Минздрава Краснодарского края Способ кожной аутопластики
RU2702152C1 (ru) * 2018-11-15 2019-10-04 Государственное бюджетное учреждение здравоохранения "Научно-исследовательский институт - краевая клиническая больница N 1 имени профессора С.В. Очаповского" Министерства здравоохранения Краснодарского края (ГБУЗ "НИИ-ККБ N 1 им. проф. Очаповского" Минздрава Краснодарского края) Способ лечения донорской раны живота
US11654057B2 (en) 2020-04-09 2023-05-23 Bio 54, Llc Devices for bleeding reduction and methods of making and using the same
CN111614010B (zh) * 2020-05-12 2021-04-13 中国长江电力股份有限公司 500kV焊接型GIL管道母线分解检修方法
JP7486227B2 (ja) * 2020-06-30 2024-05-17 株式会社 レオロジー機能食品研究所 皮膚改善用組成物
CN113967128B (zh) * 2020-07-24 2023-04-25 烟台蓝创生物技术有限公司 一种去除海藻酸盐敷料中热原的方法
US11642324B1 (en) 2022-03-01 2023-05-09 Bio 54, Llc Topical tranexamic acid compositions and methods of use thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002072113A1 (en) * 2001-03-09 2002-09-19 Intercytex Limited Wound healing using fibroblasts
EP1375647A1 (en) * 2001-03-01 2004-01-02 Centro De Investigaciones Energeticas Medioambientales Y Tecnologicas (C.I.E.M.A.T.) Artificial dermis and production method therefor

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU615414B2 (en) 1986-04-18 1991-10-03 Marrow-Tech Incorporated Process for replicating bone marrow
US4963489A (en) 1987-04-14 1990-10-16 Marrow-Tech, Inc. Three-dimensional cell and tissue culture system
FR2597499A1 (fr) 1986-04-18 1987-10-23 Merieux Inst Procede de culture microbiologique sur supports de collagene, supports pour ce procede et produits obtenus
US4837379A (en) 1988-06-02 1989-06-06 Organogenesis Inc. Fibrin-collagen tissue equivalents and methods for preparation thereof
US7208179B1 (en) * 1990-11-27 2007-04-24 The American National Red Cross Methods for treating disease and forming a supplemented fibrin matrix
DE4127570A1 (de) 1991-08-21 1993-02-25 Battelle Institut E V Verfahren zur lokalen antibakteriellen therapie von wunden
RU2023424C1 (ru) 1993-01-13 1994-11-30 Научно-производственный центр трансплантации и культивирования тканей Способ лечения раны
US5591444A (en) 1995-07-28 1997-01-07 Isolagen Technologies, Inc. Use of autologous dermal fibroblasts for the repair of skin and soft tissue defects
AU6661698A (en) 1997-02-20 1998-09-09 Gregory S. Keller Augmentation and repair of dermal, subcutaneous, and vocal cord tissue defects
JP3333108B2 (ja) 1997-04-08 2002-10-07 学校法人東海大学 上皮性組織移植片およびその製造方法
AU8224598A (en) 1997-06-26 1999-01-19 Smith & Nephew Plc Cell culture products
US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
EP1056413A4 (en) 1998-02-27 2003-08-20 Bioelastics Res Ltd INJECTABLE IMPLANTS FOR TISSUE ENHANCEMENT AND RESTORATION
AU3118499A (en) 1998-04-03 1999-10-25 Beth Israel Deaconess Medical Center Soft tissue reconstructor and method of use
US6432710B1 (en) 1998-05-22 2002-08-13 Isolagen Technologies, Inc. Compositions for regenerating tissue that has deteriorated, and methods for using such compositions
JP4606583B2 (ja) 1998-06-05 2011-01-05 オルガノジェネシス インク. 生物工学的手法による平面シート状移植補綴
US6699287B2 (en) 1998-09-24 2004-03-02 Korea Atomic Energy Research Institute Dermal scaffold using alkaline pre-treated chitosan matrix or alkaline pre-treated chitosan and alkaline pre-treated collagen mixed matrix
US6124522A (en) 1998-11-24 2000-09-26 Schroeder; Mark R. Packaging for adhesive-sided articles to allow one-handed application
EP1137380B1 (en) 1998-11-25 2004-03-31 Coloplast A/S A layered product ready for non-touch application and a method for producing such a product
RU2195889C2 (ru) 1999-05-24 2003-01-10 Парамонов Борис Алексеевич Способ дермабразии
US6733530B1 (en) 1999-08-02 2004-05-11 Eric Sun-Yin Chan Material and method for engraftment of a composite biocompatible skin graft on the neodermis of artificial skin
US6699470B1 (en) 1999-10-12 2004-03-02 Massachusetts Institute Of Technology Mesh-gel constructs for cell delivery containing enzymes and/or enzyme inhibitors to control gel degradation
WO2001032129A2 (en) 1999-11-05 2001-05-10 Gerigene Medical Corporation Augmentation and repair of age-related soft tissue defects
US6623728B2 (en) * 2000-06-30 2003-09-23 Unilever Home & Personal Care Usa Division Of Conopco, Inc. Cosmetic skin care compositions and containing gum mastic
DE10041468C1 (de) * 2000-08-23 2002-03-07 Surface Care Gmbh Hautmatrix zur Abdeckung und Regenerierung verletzter Hautpartien sowie Verfahren zu ihrer Herstellung
US7144729B2 (en) 2000-09-01 2006-12-05 Dfb Pharmaceuticals, Inc. Methods and compositions for tissue regeneration
AU9109201A (en) * 2000-09-18 2002-03-26 Organogenesis Inc Methods for treating a patient using a bioengineered flat sheet graft prostheses
DE10116362A1 (de) * 2001-04-02 2002-10-10 Biotissue Technologies Ag Zwei-Komponenten Zusammensetzungen zur in situ Herstellung v. Fibroblasten und Keratinozyten umfassenden Zelltransplantaten
US20030069639A1 (en) 2001-04-14 2003-04-10 Tom Sander Methods and compositions for repair or replacement of joints and soft tissues
US20040031067A1 (en) * 2001-10-11 2004-02-12 Meenhard Herlyn Regulation of human skin healing
US20030166274A1 (en) 2001-11-15 2003-09-04 Hewitt Charles W. Three-dimensional matrix for producing living tissue equivalents
WO2003084385A2 (en) 2002-04-02 2003-10-16 William Marsh Rice University Redifferentiated cells for repairing cartilage defects
DE10217779A1 (de) 2002-04-18 2003-11-13 Co Don Ag Konservierte Gewebematrix eines Hohlorganes, insbesondere eines Blutgefäßes, Verfahren zur Herstellung und Verwendung dieser
US20040082063A1 (en) 2002-10-18 2004-04-29 Reliance Life Sciences Pvt. Ltd. Tissue-like organization of cells and macroscopic tissue-like constructs, generated by macromass culture of cells, and the method of macromass culture
AU2005215213C1 (en) 2004-02-13 2011-04-28 Smith & Nephew Orthopaedics Ag Pharmaceutical composition comprising a fibrin matrix and dermal fibroblasts for the treatment of wounds
RU2273457C2 (ru) 2004-06-01 2006-04-10 Сергей Степанович Кузнецов Способ лечения грыж передней брюшной стенки

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1375647A1 (en) * 2001-03-01 2004-01-02 Centro De Investigaciones Energeticas Medioambientales Y Tecnologicas (C.I.E.M.A.T.) Artificial dermis and production method therefor
WO2002072113A1 (en) * 2001-03-09 2002-09-19 Intercytex Limited Wound healing using fibroblasts

Also Published As

Publication number Publication date
CA2556098A1 (en) 2005-09-01
WO2005079822A2 (en) 2005-09-01
WO2005079822A3 (en) 2005-11-03
US9526746B2 (en) 2016-12-27
AU2005215211B2 (en) 2011-11-03
AU2005215211A1 (en) 2005-09-01
JP2015063555A (ja) 2015-04-09
US9248153B2 (en) 2016-02-02
EP1718318A2 (en) 2006-11-08
JP6141603B2 (ja) 2017-06-07
US20140335183A1 (en) 2014-11-13
WO2005079821A1 (en) 2005-09-01
CA2555233A1 (en) 2005-09-01
JP6141821B2 (ja) 2017-06-07
EP1718317A1 (en) 2006-11-08
JP2015134815A (ja) 2015-07-27
JP2012192206A (ja) 2012-10-11
US20080193507A1 (en) 2008-08-14
JP2007522195A (ja) 2007-08-09
US20080226720A1 (en) 2008-09-18
JP5706058B2 (ja) 2015-04-22
US8765169B2 (en) 2014-07-01
CA2556098C (en) 2015-11-24
EP1718318B1 (en) 2014-08-13
AU2005215213B2 (en) 2010-09-09
AU2005215213A1 (en) 2005-09-01

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