CA2543374A1 - Procede et bioreacteur pour la mise en culture et la stimulation de greffons cellulaires tridimensionnels, vitaux et mecaniquement resistants - Google Patents

Procede et bioreacteur pour la mise en culture et la stimulation de greffons cellulaires tridimensionnels, vitaux et mecaniquement resistants Download PDF

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Publication number
CA2543374A1
CA2543374A1 CA002543374A CA2543374A CA2543374A1 CA 2543374 A1 CA2543374 A1 CA 2543374A1 CA 002543374 A CA002543374 A CA 002543374A CA 2543374 A CA2543374 A CA 2543374A CA 2543374 A1 CA2543374 A1 CA 2543374A1
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CA
Canada
Prior art keywords
bioreactor
transplant
chamber
reactor
stamp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002543374A
Other languages
English (en)
Inventor
Ronny Schulz
Augustinus Bader
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2543374A1 publication Critical patent/CA2543374A1/fr
Abandoned legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10—Perfusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Mechanical Engineering (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
CA002543374A 2003-10-21 2004-10-19 Procede et bioreacteur pour la mise en culture et la stimulation de greffons cellulaires tridimensionnels, vitaux et mecaniquement resistants Abandoned CA2543374A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE2003149484 DE10349484A1 (de) 2003-10-21 2003-10-21 Verfahren und Bioreaktor zum Kultivieren und Stimulieren von dreidimensionalen, vitalen und mechanisch widerstandsfähigen Zelltransplantaten
DE10349484.7 2003-10-21
PCT/EP2004/011788 WO2005040332A2 (fr) 2003-10-21 2004-10-19 Procede et bioreacteur pour la mise en culture et la stimulation de greffons cellulaires tridimensionnels, vitaux et mecaniquement resistants

Publications (1)

Publication Number Publication Date
CA2543374A1 true CA2543374A1 (fr) 2005-05-06

Family

ID=34484964

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002543374A Abandoned CA2543374A1 (fr) 2003-10-21 2004-10-19 Procede et bioreacteur pour la mise en culture et la stimulation de greffons cellulaires tridimensionnels, vitaux et mecaniquement resistants

Country Status (7)

Country Link
EP (1) EP1675939A2 (fr)
JP (1) JP2007508830A (fr)
CN (1) CN1898375A (fr)
CA (1) CA2543374A1 (fr)
DE (1) DE10349484A1 (fr)
RU (1) RU2370534C2 (fr)
WO (1) WO2005040332A2 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8431401B2 (en) 2006-07-10 2013-04-30 Takagi Industrial Co., Ltd. Method of cultivating cell or tissue
US9005958B2 (en) 2006-07-10 2015-04-14 Purpose Company Limited Cell or tissue cultivation apparatus and method of cultivation

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005049905A1 (de) * 2005-10-17 2007-04-19 Medizinische Hochschule Hannover Verfahren und Vorrichtung zur Herstellung eines Gelenkersatzes
ITMI20071945A1 (it) * 2007-10-09 2009-04-10 Milano Politecnico Bioreattore per la generazione e la stimolazione meccanica complessa di tessuto biologico ingegnerizzato.
EP2288688A2 (fr) * 2008-03-25 2011-03-02 Novatissue Gmbh Bioréacteur à perfusion pour produire des tissus humains ou animaux
DE102008015633B4 (de) * 2008-03-25 2010-07-01 Nova Tissue Gmbh Perfundierbarer Bioreaktor zur Herstellung und/oder Kultivierung eines menschlichen oder tierischen Blutgefäßes und/oder eines menschlichen oder tierischen Gewebes
AT506826B1 (de) * 2008-05-23 2010-03-15 Greiner Bio One Gmbh Bioreaktor und verfahren zum kultivieren von zellen und geweben
DE102008050424B4 (de) 2008-10-08 2010-11-25 Universität Leipzig Verfahren und Vorrichtung zur homogenen Verteilung einer zellulären Suspension in porösem Trägermaterial für die Herstellung von vitalem biologischem Ersatzgewebe
EP2184347A3 (fr) 2008-11-06 2011-05-18 Georg N. Duda Nouveaux composants et nouveau système de bioréacteurs pour la culture et la stimulation mécanique de matériau biologique
ITMI20090388A1 (it) * 2009-03-13 2010-09-14 Istituto Ortopedico Galeazzi S P A Bioreattore per la coltura di cellule o tessuti biologici, relativo metodo e sis tema multistazione
DE102009050498B4 (de) 2009-10-23 2015-08-06 Universität Leipzig Perfundierbarer Bioreaktor zur Herstellung von menschlichen und tierischen Geweben
RU2012132445A (ru) 2009-12-29 2014-02-10 У.Р. Грейс Энд Ко.-Конн. Композиции для образования пленок, имеющих желательную степень матирования, и способы их получения и применения
DE102010026369B4 (de) 2010-07-07 2015-07-30 Zellwerk Gmbh Verfahren und Druck-Drehbett-Bioreaktor zur dynamischen Expansion und/oder Differenzierung von Stammzellen oder primären Zellen humanen und tierischen Ursprungs
WO2012118304A2 (fr) * 2011-02-28 2012-09-07 주식회사 코리아본뱅크 Dispositif pour incuber un implant de tissu mou allogène
KR101313769B1 (ko) 2011-02-28 2013-10-01 주식회사 셀루메드 동종 연조직 이식체 배양 장치
RU2482180C2 (ru) * 2011-07-14 2013-05-20 Алексей Вячеславович Ковалев Биореактор для выращивания тканеинженерных конструкций
CN103930066A (zh) * 2011-09-12 2014-07-16 奥加诺沃公司 用于工程化的可植入组织和器官的平台及其制备方法
DE102012101078A1 (de) * 2012-02-09 2013-10-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Stimulationszelle und Verfahren zur in vitro Stimulation von Zellen oder Geweben
CN105121621B (zh) * 2012-10-18 2019-08-02 张永新 用于细胞动静态交替培养的生物反应器系统及其方法
ITFI20130220A1 (it) * 2013-09-20 2015-03-21 Azienda Ospedaliero Universitaria P Isana Apparato e processo per la preparazione di una protesi tissutale biomimetica della membrana timpanica
ITUB20160272A1 (it) * 2016-01-22 2017-07-22 Univ Degli Studi Di Palermo Bioreattore a perfusione autosufficiente monouso per crescite cellulari 3D
RU2612904C1 (ru) * 2016-04-15 2017-03-13 Евгений Александрович Тоневицкий Способ и микрофлюидный чип для культивирования клеток или клеточной модели
FR3081168B1 (fr) * 2018-05-21 2022-03-11 Univ Bordeaux Systeme de culture cellulaire en bioreacteur
DE102018122745B3 (de) * 2018-09-17 2019-12-19 Naturin Viscofan Gmbh Vorrichtung zur Medienzufuhr oder -abfuhr, Kulturgefäß mit einer solchen Vorrichtung und Verfahren zur Kultivierung von mikrobiologischen Systemen unter Verwendung eines solchen Kulturgefäßes
RU190863U1 (ru) * 2019-02-15 2019-07-15 Федеральное государственное бюджетное учреждение "Российский ордена Трудового Красного Знамени научно-исследовательский институт травматологии и ортопедии имени Р.Р. Вредена" Министерства здравоохранения Российской Федерации (ФГБУ "РНИИТО им. Р.Р. Вредена" Минздрава России) Устройство для совмещения клеточной культуры и биодеградируемого носителя
CN111705034A (zh) * 2020-06-30 2020-09-25 山东省医药生物技术研究中心（山东省病毒研究所） 一种高效促进软骨细胞增殖的方法
CN111996120A (zh) * 2020-09-25 2020-11-27 南通纺织丝绸产业技术研究院 一种带有微电流刺激功能的细胞培养装置
AT523906B1 (de) * 2020-10-02 2022-01-15 Inncellys Gmbh Inkubationskammer

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4306661C2 (de) * 1993-03-03 1995-04-20 Michael Dipl Biol Sittinger Verfahren zum Herstellen eines Implantates aus Zellkulturen
AU5931896A (en) * 1995-06-07 1996-12-30 Advanced Tissue Sciences, Inc. Apparatus and method for sterilizing, seeding, culturing, st oring, shipping, and testing replacement cartilage tissue co nstructs
DE19808055B4 (de) * 1998-02-27 2007-02-08 Adamietz, Peter, Dr.rer.nat. Verfahren und Apparatur zur Herstellung von dreidimensionalen Gewebezellkulturen
DE19962456A1 (de) * 1999-12-22 2001-07-12 Biotechnologie Ges Mittelhesse Verfahren und Apparatur zur Herstellung, Untersuchung und mechanischen Stimulation dreidimensionaler Gewebezellkulturen
US7585323B2 (en) * 2000-05-05 2009-09-08 Medlden, Llc In vitro mechanical loading of musculoskeletal tissues
DE10061704A1 (de) * 2000-12-12 2002-06-20 Hans Joerg Bauer Verfahren und Vorrichtung zur Herstellung von biologischem Gewebe in einer Wachstumskammer
JP2003061642A (ja) * 2001-08-30 2003-03-04 Takagi Ind Co Ltd 細胞・組織培養装置
DE10201259A1 (de) * 2002-01-15 2003-08-28 Augustinus Bader Vorrichtung zum Züchten oder Kultivieren von Zellen in einem dosenartigen Behälter

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8431401B2 (en) 2006-07-10 2013-04-30 Takagi Industrial Co., Ltd. Method of cultivating cell or tissue
US9005958B2 (en) 2006-07-10 2015-04-14 Purpose Company Limited Cell or tissue cultivation apparatus and method of cultivation
US9670450B2 (en) 2006-07-10 2017-06-06 Purpose Company Limited Cell or tissue cultivation apparatus and method of cultivation

Also Published As

Publication number Publication date
RU2006117360A (ru) 2007-11-27
CN1898375A (zh) 2007-01-17
RU2370534C2 (ru) 2009-10-20
DE10349484A1 (de) 2005-05-25
WO2005040332A2 (fr) 2005-05-06
WO2005040332A3 (fr) 2005-06-30
JP2007508830A (ja) 2007-04-12
EP1675939A2 (fr) 2006-07-05

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued