CA2515096A1 - Gene expression markers for response to egfr inhibitor drugs - Google Patents

Gene expression markers for response to egfr inhibitor drugs Download PDF

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Publication number
CA2515096A1
CA2515096A1 CA002515096A CA2515096A CA2515096A1 CA 2515096 A1 CA2515096 A1 CA 2515096A1 CA 002515096 A CA002515096 A CA 002515096A CA 2515096 A CA2515096 A CA 2515096A CA 2515096 A1 CA2515096 A1 CA 2515096A1
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CA
Canada
Prior art keywords
cancer
expression
genes
patient
dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002515096A
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English (en)
French (fr)
Inventor
David Agus
Steve Shak
Maureen T. Cronin
Joffre B. Baker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cedars Sinai Medical Center
Genomic Health Inc
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Individual
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Filing date
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Publication of CA2515096A1 publication Critical patent/CA2515096A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA002515096A 2003-02-06 2004-02-05 Gene expression markers for response to egfr inhibitor drugs Abandoned CA2515096A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44596803P 2003-02-06 2003-02-06
US60/445,968 2003-02-06
PCT/US2004/003596 WO2004071572A2 (en) 2003-02-06 2004-02-05 Gene expression markers for response to egfr inhibitor drugs

Publications (1)

Publication Number Publication Date
CA2515096A1 true CA2515096A1 (en) 2004-08-26

Family

ID=32869443

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002515096A Abandoned CA2515096A1 (en) 2003-02-06 2004-02-05 Gene expression markers for response to egfr inhibitor drugs

Country Status (6)

Country Link
US (2) US20040157255A1 (enExample)
EP (1) EP1590487A2 (enExample)
JP (1) JP2006521793A (enExample)
AU (2) AU2004211955B2 (enExample)
CA (1) CA2515096A1 (enExample)
WO (1) WO2004071572A2 (enExample)

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Also Published As

Publication number Publication date
AU2009208748A1 (en) 2009-09-10
EP1590487A2 (en) 2005-11-02
WO2004071572A2 (en) 2004-08-26
US20080176229A1 (en) 2008-07-24
JP2006521793A (ja) 2006-09-28
AU2004211955A1 (en) 2004-08-26
US20040157255A1 (en) 2004-08-12
WO2004071572A3 (en) 2005-01-13
AU2004211955B2 (en) 2009-05-14

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