MX2010001582A - Marcador predictivo para tratamiento con el inhibidor del receptor del factor de crecimiento epidermico. - Google Patents
Marcador predictivo para tratamiento con el inhibidor del receptor del factor de crecimiento epidermico.Info
- Publication number
- MX2010001582A MX2010001582A MX2010001582A MX2010001582A MX2010001582A MX 2010001582 A MX2010001582 A MX 2010001582A MX 2010001582 A MX2010001582 A MX 2010001582A MX 2010001582 A MX2010001582 A MX 2010001582A MX 2010001582 A MX2010001582 A MX 2010001582A
- Authority
- MX
- Mexico
- Prior art keywords
- egfr inhibitors
- predictive markers
- inhibitors treatment
- treatment
- predictive
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/15—Medicinal preparations ; Physical properties thereof, e.g. dissolubility
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Oncology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención proporciona biomarcadores que son predictivos para la respuesta al tratamiento con un inhibidor de EGFR en pacientes con cáncer. Los marcadores son los genes GBAS, APOH, SCYL3, PMS2CL, PRODH, SERFIA, URG4A y LRRC31.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07114336 | 2007-08-14 | ||
PCT/EP2008/006512 WO2009021673A1 (en) | 2007-08-14 | 2008-08-07 | Predictive markers for egfr inhibitors treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010001582A true MX2010001582A (es) | 2010-06-02 |
Family
ID=39876728
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010001582A MX2010001582A (es) | 2007-08-14 | 2008-08-07 | Marcador predictivo para tratamiento con el inhibidor del receptor del factor de crecimiento epidermico. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20110218212A1 (es) |
EP (1) | EP2188390A1 (es) |
JP (1) | JP2010535516A (es) |
KR (1) | KR20100037639A (es) |
CN (1) | CN101784674A (es) |
AU (1) | AU2008286406A1 (es) |
BR (1) | BRPI0815545A2 (es) |
CA (1) | CA2695064A1 (es) |
MX (1) | MX2010001582A (es) |
WO (1) | WO2009021673A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI449791B (zh) * | 2011-07-05 | 2014-08-21 | Univ Nat Taiwan | 預測egfr突變肺腺癌病患對藥物治療的反應與預後之方法 |
EP3074530A1 (en) * | 2013-11-26 | 2016-10-05 | Integragen | A method for predicting responsiveness to a treatment with an egfr inhibitor |
CN112063715B (zh) * | 2020-09-07 | 2021-09-14 | 清华大学 | 一种用于肝细胞癌早期筛查的系统 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5202231A (en) | 1987-04-01 | 1993-04-13 | Drmanac Radoje T | Method of sequencing of genomes by hybridization of oligonucleotide probes |
US5525464A (en) | 1987-04-01 | 1996-06-11 | Hyseq, Inc. | Method of sequencing by hybridization of oligonucleotide probes |
US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
US5795716A (en) | 1994-10-21 | 1998-08-18 | Chee; Mark S. | Computer-aided visualization and analysis system for sequence evaluation |
CA2515096A1 (en) * | 2003-02-06 | 2004-08-26 | Genomic Health, Inc. | Gene expression markers for response to egfr inhibitor drugs |
KR101126560B1 (ko) * | 2003-05-30 | 2012-04-05 | 도꾜 다이가꾸 | 약제 반응 예측 방법 |
ATE477495T1 (de) | 2005-03-16 | 2010-08-15 | Osi Pharm Inc | Biologische marker prediktiv für das ansprechen von krebs auf inhibitoren der kinase des rezeptors für epidermalen wachstumsfaktor |
AR053272A1 (es) * | 2005-05-11 | 2007-04-25 | Hoffmann La Roche | Determinacion de responsivos a la quimioterapia |
WO2007067500A2 (en) | 2005-12-05 | 2007-06-14 | Genomic Health, Inc. | Predictors of patient response to treatment with egfr inhibitors |
-
2008
- 2008-08-07 CN CN200880102888A patent/CN101784674A/zh active Pending
- 2008-08-07 EP EP08785418A patent/EP2188390A1/en not_active Withdrawn
- 2008-08-07 WO PCT/EP2008/006512 patent/WO2009021673A1/en active Application Filing
- 2008-08-07 CA CA2695064A patent/CA2695064A1/en not_active Abandoned
- 2008-08-07 KR KR1020107003317A patent/KR20100037639A/ko not_active Application Discontinuation
- 2008-08-07 JP JP2010520463A patent/JP2010535516A/ja active Pending
- 2008-08-07 BR BRPI0815545-3A2A patent/BRPI0815545A2/pt not_active Application Discontinuation
- 2008-08-07 US US12/672,924 patent/US20110218212A1/en not_active Abandoned
- 2008-08-07 AU AU2008286406A patent/AU2008286406A1/en not_active Abandoned
- 2008-08-07 MX MX2010001582A patent/MX2010001582A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
CA2695064A1 (en) | 2009-02-19 |
CN101784674A (zh) | 2010-07-21 |
WO2009021673A1 (en) | 2009-02-19 |
KR20100037639A (ko) | 2010-04-09 |
BRPI0815545A2 (pt) | 2015-02-10 |
US20110218212A1 (en) | 2011-09-08 |
AU2008286406A1 (en) | 2009-02-19 |
EP2188390A1 (en) | 2010-05-26 |
JP2010535516A (ja) | 2010-11-25 |
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Legal Events
Date | Code | Title | Description |
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FA | Abandonment or withdrawal |