CA2502272C - Biosensor - Google Patents

Biosensor Download PDF

Info

Publication number
CA2502272C
CA2502272C CA2502272A CA2502272A CA2502272C CA 2502272 C CA2502272 C CA 2502272C CA 2502272 A CA2502272 A CA 2502272A CA 2502272 A CA2502272 A CA 2502272A CA 2502272 C CA2502272 C CA 2502272C
Authority
CA
Canada
Prior art keywords
glucose
biosensor
sample
binding
ligand
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2502272A
Other languages
English (en)
French (fr)
Other versions
CA2502272A1 (en
Inventor
Homme W. Hellinga
Loren L. Looger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duke University
Original Assignee
Duke University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duke University filed Critical Duke University
Publication of CA2502272A1 publication Critical patent/CA2502272A1/en
Application granted granted Critical
Publication of CA2502272C publication Critical patent/CA2502272C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
CA2502272A 2002-10-16 2003-10-16 Biosensor Expired - Fee Related CA2502272C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41835902P 2002-10-16 2002-10-16
US60/418,359 2002-10-16
PCT/US2003/032581 WO2004036176A2 (en) 2002-10-16 2003-10-16 Biosensor

Publications (2)

Publication Number Publication Date
CA2502272A1 CA2502272A1 (en) 2004-04-29
CA2502272C true CA2502272C (en) 2011-10-11

Family

ID=32107920

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2502272A Expired - Fee Related CA2502272C (en) 2002-10-16 2003-10-16 Biosensor

Country Status (13)

Country Link
US (3) US9625458B2 (US20080166747A1-20080710-P00010.png)
EP (1) EP1552303B1 (US20080166747A1-20080710-P00010.png)
JP (1) JP4571499B2 (US20080166747A1-20080710-P00010.png)
KR (1) KR101107630B1 (US20080166747A1-20080710-P00010.png)
CN (1) CN100492010C (US20080166747A1-20080710-P00010.png)
AT (1) ATE423318T1 (US20080166747A1-20080710-P00010.png)
AU (1) AU2003277377B2 (US20080166747A1-20080710-P00010.png)
CA (1) CA2502272C (US20080166747A1-20080710-P00010.png)
DE (1) DE60326256D1 (US20080166747A1-20080710-P00010.png)
DK (1) DK1552303T3 (US20080166747A1-20080710-P00010.png)
ES (1) ES2321931T3 (US20080166747A1-20080710-P00010.png)
HK (1) HK1080937A1 (US20080166747A1-20080710-P00010.png)
WO (1) WO2004036176A2 (US20080166747A1-20080710-P00010.png)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100627206B1 (ko) * 1998-07-30 2006-09-25 유니챰 가부시키가이샤 박형 내용물용 용기
ES2321931T3 (es) 2002-10-16 2009-06-15 Duke University Biosensores para detectar glucosa.
WO2005007806A2 (en) * 2003-05-07 2005-01-27 Duke University Protein design for receptor-ligand recognition and binding
PL1642117T3 (pl) * 2003-06-20 2018-11-30 F.Hoffmann-La Roche Ag Pasek odczynnika do paska testowego
EP1642124B1 (en) * 2003-06-20 2017-11-29 Roche Diabetes Care GmbH Electrochemical biosensors
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US8679853B2 (en) 2003-06-20 2014-03-25 Roche Diagnostics Operations, Inc. Biosensor with laser-sealed capillary space and method of making
US20050112685A1 (en) * 2003-11-26 2005-05-26 Amiss Terry J. Compositions and methods for measuring analyte concentrations
US20050181141A1 (en) * 2004-02-18 2005-08-18 Aiden Flanagan Laser-induced explosive vaporization coating method, associated system, and device made by the method
US20050181116A1 (en) * 2004-02-18 2005-08-18 Rob Worsham Method for coating a medical device using a matrix assisted pulsed-laser evaporation technique and associated system and medical device
US20050188921A1 (en) * 2004-02-27 2005-09-01 Anthony Malone Matrix assisted pulsed-laser evaporation technique for coating a medical device and associated system and medical device
US7563891B2 (en) * 2004-05-21 2009-07-21 Becton, Dickinson & Company Long wavelength thiol-reactive fluorophores
WO2006044612A2 (en) * 2004-10-14 2006-04-27 Carnegie Institution Of Washington Development of sensitive fret sensors and methods of using the same
US7777016B2 (en) * 2004-10-14 2010-08-17 Carnegie Institution Of Washington Neurotransmitter sensors and methods of using the same
US7545272B2 (en) 2005-02-08 2009-06-09 Therasense, Inc. RF tag on test strips, test strip vials and boxes
US20090178149A1 (en) * 2005-03-03 2009-07-09 Sylvie Lalonde Polyamine Sensors and Methods of Using the Same
AU2005328651A1 (en) * 2005-03-04 2006-09-14 Carnegie Institution Of Washington Environmentally stable sensors and methods of using the same
US20070154947A1 (en) * 2005-08-31 2007-07-05 The Trustees Of Princeton University Chemical biodiscriminator
ATE489397T1 (de) * 2005-10-14 2010-12-15 Carnegie Inst Of Washington Saccharose-biosensoren und verwendungsverfahren dafür
ATE481412T1 (de) * 2005-10-14 2010-10-15 Carnegie Inst Of Washington Phosphat-biosensoren und verfahren zu deren anwendung
CA2627545A1 (en) * 2005-11-16 2007-05-24 Carnegie Institution Of Washington Multimeric biosensors and methods of using the same
WO2008131360A1 (en) 2007-04-20 2008-10-30 Becton, Dickinson And Company Hydrogel compositions
EP2150586B1 (en) * 2007-05-22 2018-03-14 Becton, Dickinson and Company Dyes having ratiometric fluorescence response for detecting metabolites
US8129532B2 (en) * 2007-08-03 2012-03-06 The University Of Connecticut Amino(oligo)thiophene dyes, preparation thereof, and optical methods of use
WO2009021039A1 (en) * 2007-08-06 2009-02-12 University Of Kentucky Research Foundation Device for detection of molecules of interest
US8741591B2 (en) 2009-10-09 2014-06-03 The Research Foundation For The State University Of New York pH-insensitive glucose indicator protein
US9719992B2 (en) 2011-10-07 2017-08-01 Howard Hughes Medical Institute Genetically encoded biosensors
US10684282B2 (en) 2011-10-07 2020-06-16 Howard Hughes Medical Institute Genetically encoded biosensors
US10466247B2 (en) 2012-11-20 2019-11-05 Becton, Dickinson And Company System and method for diagnosing sensor performance using analyte-independent ratiometric signals
US20140212987A1 (en) * 2013-01-30 2014-07-31 Siemens Healthcare Diagnostics Inc. Signal Ratio in Assay Calibrators
KR101455244B1 (ko) 2013-02-04 2014-10-31 경희대학교 산학협력단 Afm과 탐침형 센서를 이용한 세포독성의 정량적 평가시스템 및 방법
CN105683210B (zh) 2013-08-23 2020-07-14 贝林格尔·英格海姆Rcv两合公司 用于细胞破碎和/或回收生物分子的微粒
US10379125B2 (en) 2013-12-27 2019-08-13 Becton, Dickinson And Company System and method for dynamically calibrating and measuring analyte concentration in diabetes management monitors
EP3362468A4 (en) 2015-10-13 2018-08-22 The Research Foundation for the State University of New York Cleavable fusion tag for protein overexpression and purification
EP3377643A4 (en) 2015-11-20 2019-10-02 Duke University GLUCOSE Biosensor and uses thereof
EP3377899A4 (en) 2015-11-20 2019-10-02 Duke University BICARBONATE BIOSENSORS, CALCIUM BIOSENSORS AND USES THEREOF
WO2017087916A2 (en) 2015-11-20 2017-05-26 Duke University Thermostable glucose biosensors and uses thereof
US11099176B2 (en) 2015-11-20 2021-08-24 Duke University Lactate biosensors and uses thereof
EP3377904B1 (en) 2015-11-20 2024-05-01 Duke University Urea biosensors and uses thereof
GB201714478D0 (en) * 2017-09-08 2017-10-25 Univ Bristol Sensor
WO2021022245A1 (en) * 2019-08-01 2021-02-04 The Trustees Of Indiana University Glyphosate biosensor
CN113980992B (zh) * 2021-12-29 2022-03-25 中国科学院天津工业生物技术研究所 一种l-半胱氨酸生物传感器及其应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9301270D0 (sv) * 1993-04-19 1993-04-17 Biosensor
KR100259761B1 (ko) 1996-03-15 2000-07-01 타이도 나오카타 에스에이치기 표지용시약, 그의 제조방법 및 이를 이용한 표지법
US6130037A (en) * 1996-04-25 2000-10-10 Pence And Mcgill University Biosensor device and method
SE9602545L (sv) 1996-06-25 1997-12-26 Michael Mecklenburg Metod för att diskriminera komplexa biologiska prover
AU7715898A (en) 1997-05-27 1998-12-30 Duke University Synthetic metalloproteins and method of preparation thereof
AUPO714897A0 (en) 1997-06-03 1997-06-26 Australian Membrane And Biotechnology Research Institute Model membrane systems
US6013459A (en) * 1997-06-12 2000-01-11 Clinical Micro Sensors, Inc. Detection of analytes using reorganization energy
US6277627B1 (en) 1997-12-31 2001-08-21 Duke University Biosensor
EP1070257A2 (en) 1998-04-06 2001-01-24 Lerner Pharmaceuticals, Inc. Directed evolution biosensors
IL124903A0 (en) * 1998-06-15 1999-01-26 Bauer Alan Josef An enzyme biosensor
US6197534B1 (en) * 1998-07-17 2001-03-06 Joseph R. Lakowicz Engineered proteins for analyte sensing
US6663862B1 (en) * 1999-06-04 2003-12-16 Duke University Reagents for detection and purification of antibody fragments
GB9923146D0 (en) * 1999-09-30 1999-12-01 Imperial College Detector array
CA2457964C (en) * 2001-08-28 2013-05-28 Duke University Biosensor
US6855556B2 (en) * 2002-01-04 2005-02-15 Becton, Dickinson And Company Binding protein as biosensors
ES2321931T3 (es) 2002-10-16 2009-06-15 Duke University Biosensores para detectar glucosa.
WO2005007806A2 (en) 2003-05-07 2005-01-27 Duke University Protein design for receptor-ligand recognition and binding
EP2150586B1 (en) * 2007-05-22 2018-03-14 Becton, Dickinson and Company Dyes having ratiometric fluorescence response for detecting metabolites
WO2008154332A1 (en) * 2007-06-06 2008-12-18 Becton, Dickinson And Company Near-infrared dyes as surface enhanced raman scattering reporters
US9023661B2 (en) * 2007-10-18 2015-05-05 Becton, Dickinson And Company Visual glucose sensor and methods of use thereof

Also Published As

Publication number Publication date
DK1552303T3 (da) 2009-05-25
US20080166747A1 (en) 2008-07-10
US10712341B2 (en) 2020-07-14
KR20050083772A (ko) 2005-08-26
ATE423318T1 (de) 2009-03-15
EP1552303A2 (en) 2005-07-13
US20170322209A1 (en) 2017-11-09
US20040118681A1 (en) 2004-06-24
HK1080937A1 (en) 2006-05-04
EP1552303B1 (en) 2009-02-18
EP1552303A4 (en) 2006-12-27
US9625458B2 (en) 2017-04-18
CN1705882A (zh) 2005-12-07
DE60326256D1 (de) 2009-04-02
WO2004036176A2 (en) 2004-04-29
CN100492010C (zh) 2009-05-27
CA2502272A1 (en) 2004-04-29
AU2003277377B2 (en) 2009-05-21
JP4571499B2 (ja) 2010-10-27
KR101107630B1 (ko) 2012-01-25
AU2003277377A1 (en) 2004-05-04
JP2006503293A (ja) 2006-01-26
ES2321931T3 (es) 2009-06-15
WO2004036176A3 (en) 2004-07-29

Similar Documents

Publication Publication Date Title
CA2502272C (en) Biosensor
De Lorimier et al. Construction of a fluorescent biosensor family
Salins et al. A novel reagentless sensing system for measuring glucose based on the galactose/glucose-binding protein
CA2316199C (en) Biosensor
Mohsin et al. Genetically encoded FRET-based nanosensor for in vivo measurement of leucine
Khan et al. Fluorescence intensity-and lifetime-based glucose sensing using an engineered high-Kd mutant of glucose/galactose-binding protein
Brennan Preparation and entrapment of fluorescently labeled proteins for the development of reagentless optical biosensors
US9817004B2 (en) Development and use of cysteine-labeled fluorescent probes of unbound analytes
Ahmad et al. Live cell imaging of vitamin B12 dynamics by genetically encoded fluorescent nanosensor
Tian et al. Structure‐based design of robust glucose biosensors using a Thermotoga maritima periplasmic glucose‐binding protein
Sakaguchi-Mikami et al. Engineering of ligand specificity of periplasmic binding protein for glucose sensing
Vercillo et al. Analysis of ligand binding to a ribose biosensor using site‐directed mutagenesis and fluorescence spectroscopy
Yu et al. Highly Sensitive and Selective Detection of Inorganic Phosphates in the Water Environment by Biosensors Based on Bioluminescence Resonance Energy Transfer
Hellinga et al. Biosensor
Dikici et al. Drug detection based on the conformational changes of calmodulin and the fluorescence of its enhanced green fluorescent protein fusion partner
Soleja et al. Enhanced sensitivity and detection range of FRET-based vitamin B 12 nanosensor
Hellinga et al. Biosensor
Grünewald Periplasmic binding proteins in biosensing applications
Mohsin et al. Genetically encoded FRET-based nanosensor for in vivo monitoring of zinc concentration in physiological environment of living cell
US8852882B2 (en) Biosensors and their use
EP4100956A1 (en) Improved processes for rationally-designing and producing biomolecules
Shetty et al. Recombinant methods in protein and whole-cell biosensing
Turner Cell and Protein-based Sensing Systems for the Detection of Environmentally and Physiologically Relevant Molecules
Tian Protein engineering and design of thermostable biosensors
EP2103936A1 (en) Reagentless fluorescent biosensors comprising a designed ankyrin repeat module and methods of their design and use

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20191016