CA2500472A1 - Genes and polypeptides relating to human pancreatic cancers - Google Patents
Genes and polypeptides relating to human pancreatic cancers Download PDFInfo
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- CA2500472A1 CA2500472A1 CA002500472A CA2500472A CA2500472A1 CA 2500472 A1 CA2500472 A1 CA 2500472A1 CA 002500472 A CA002500472 A CA 002500472A CA 2500472 A CA2500472 A CA 2500472A CA 2500472 A1 CA2500472 A1 CA 2500472A1
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
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- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Oncology (AREA)
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- General Physics & Mathematics (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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| US41487202P | 2002-09-30 | 2002-09-30 | |
| US60/414,872 | 2002-09-30 | ||
| US45088903P | 2003-02-28 | 2003-02-28 | |
| US60/450,889 | 2003-02-28 | ||
| PCT/JP2003/011713 WO2004031411A2 (en) | 2002-09-30 | 2003-09-12 | Genes and polypeptides relating to human pancreatic cancers |
Publications (1)
| Publication Number | Publication Date |
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| CA2500472A1 true CA2500472A1 (en) | 2004-04-15 |
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| CA002500472A Abandoned CA2500472A1 (en) | 2002-09-30 | 2003-09-12 | Genes and polypeptides relating to human pancreatic cancers |
| CA002500482A Abandoned CA2500482A1 (en) | 2002-09-30 | 2003-09-17 | Method for diagnosing pancreatic cancer |
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| Application Number | Title | Priority Date | Filing Date |
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| CA002500482A Abandoned CA2500482A1 (en) | 2002-09-30 | 2003-09-17 | Method for diagnosing pancreatic cancer |
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| US20060024692A1 (en) * | 2002-09-30 | 2006-02-02 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers |
| US7790867B2 (en) | 2002-12-05 | 2010-09-07 | Rosetta Genomics Inc. | Vaccinia virus-related nucleic acids and microRNA |
| US7888497B2 (en) | 2003-08-13 | 2011-02-15 | Rosetta Genomics Ltd. | Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof |
| WO2005083086A2 (en) * | 2004-02-27 | 2005-09-09 | Oncotherapy Science, Inc. | Epha4 as therapeutic target of prc and pdaca |
| US7939251B2 (en) * | 2004-05-06 | 2011-05-10 | Roche Molecular Systems, Inc. | SENP1 as a marker for cancer |
| US7687616B1 (en) | 2004-05-14 | 2010-03-30 | Rosetta Genomics Ltd | Small molecules modulating activity of micro RNA oligonucleotides and micro RNA targets and uses thereof |
| JP5697297B2 (ja) | 2004-05-14 | 2015-04-08 | ロゼッタ ジノミクス リミテッド | マイクロｎａｓおよびその使用 |
| ES2555994T3 (es) | 2004-05-21 | 2016-01-12 | The Board Of Trustees Of The University Of Arkansas System | Uso de perfiles de expresión génica para predecir la supervivencia en un paciente con cáncer |
| US7795419B2 (en) | 2004-05-26 | 2010-09-14 | Rosetta Genomics Ltd. | Viral and viral associated miRNAs and uses thereof |
| WO2006038904A2 (en) * | 2004-08-06 | 2006-04-13 | Applera Corporation | Method and compositions for treating diseases targeting e-cadherin |
| DE102004042822A1 (de) * | 2004-08-31 | 2006-03-16 | Technische Universität Dresden | Verbindungen und Methoden zur Behandlung, Diagnose und Prognose bei Pankreaserkrankungen |
| DE102004049897B4 (de) | 2004-10-13 | 2007-11-22 | Sirs-Lab Gmbh | Verfahren zur Unterscheidung zwischen nichtinfektiösen und infektiösen Ursachen eines Multiorganversagens |
| JP2009502735A (ja) * | 2005-07-28 | 2009-01-29 | オンコセラピー・サイエンス株式会社 | Ｖｉｖｉｔポリペプチド、これを含む治療物質、および抗癌剤をスクリーニングする方法 |
| US20080050726A1 (en) | 2005-09-19 | 2008-02-28 | Yixin Wang | Methods for diagnosing pancreatic cancer |
| JP5321780B2 (ja) | 2006-02-10 | 2013-10-23 | オンコセラピー・サイエンス株式会社 | 肺癌の治療方法 |
| CA2643790A1 (en) | 2006-02-28 | 2007-09-13 | Oncotherapy Science, Inc. | Methods for damaging cells using effector functions of anti-epha4 antibodies |
| JP2009528507A (ja) * | 2006-03-02 | 2009-08-06 | オンコセラピー・サイエンス株式会社 | Ｒｅｇ４タンパク質を用いて膵癌を診断する方法 |
| CN1904072B (zh) * | 2006-07-28 | 2012-07-18 | 浙江大学 | 一组筛选胰腺导管腺癌的基因组合及应用 |
| KR20090040391A (ko) * | 2006-08-18 | 2009-04-23 | 온코세라피 사이언스 가부시키가이샤 | Ｒｅｇ４ 또는 ｋｉａａ０１０１을 과발현하는 암의 예방 및 치료 기술 |
| US7811778B2 (en) * | 2006-09-06 | 2010-10-12 | Vanderbilt University | Methods of screening for gastrointestinal cancer |
| US20100105571A1 (en) | 2007-03-27 | 2010-04-29 | Carl Arne Krister Borrebaeck | Protein Signature/Markers for the Detection of Adenocarcinoma |
| UA100127C2 (ru) | 2007-08-20 | 2012-11-26 | Онкотерапи Саенс, Инк. | Пептид cdh3 и лекарственное средство, содержащее его |
| RU2487886C2 (ru) | 2007-08-20 | 2013-07-20 | Онкотерапи Сайенс, Инк. | Пептид foxm1 и включающее его медицинское средство |
| CN102137929B (zh) | 2008-06-30 | 2013-07-10 | 肿瘤疗法科学股份有限公司 | 用放射性同位素标记物标记的抗cdh3抗体及其用途 |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| RU2011111387A (ru) * | 2008-08-27 | 2012-10-10 | Онкотерапи Сайенс, Инк. (Jp) | Syngr4 в качестве генов-мишеней для терапии и диагностики рака |
| US10359425B2 (en) | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100135991A1 (en) * | 2008-11-17 | 2010-06-03 | Chiu-Chen Huang | Antibodies recognizing oxygen-regulated protein 150 expressed on cancer cells and methods of using same |
| TWI469791B (zh) * | 2009-02-18 | 2015-01-21 | Oncotherapy Science Inc | Ｆｏｘｍ１胜肽以及含此胜肽之疫苗 |
| DE102010043541B4 (de) * | 2009-12-16 | 2012-01-26 | Technische Universität Dresden | Verfahren und Mittel zur Vorhersage der Überlebensdauer beim Pankreaskarzinom durch Analyse von Biomarkern |
| CN102781964B (zh) | 2009-12-28 | 2015-11-25 | 肿瘤疗法科学股份有限公司 | 抗cdh3抗体及其用途 |
| JP2013518560A (ja) * | 2010-02-03 | 2013-05-23 | オンコセラピー・サイエンス株式会社 | がんの治療および診断の標的遺伝子としてのｗｈｓｃ１およびｗｈｓｃ１ｌ１ |
| US20130140452A1 (en) * | 2010-06-01 | 2013-06-06 | Beate Kamlage | Means and methods for diagnosing pancreatic cancer in a subject |
| JP5905003B2 (ja) | 2010-07-09 | 2016-04-20 | ソマロジック・インコーポレーテッド | 肺癌バイオマーカーとその使用 |
| JP5931874B2 (ja) * | 2010-08-13 | 2016-06-08 | ソマロジック・インコーポレーテッド | 膵癌バイオマーカーおよびその使用 |
| US20140031250A1 (en) | 2010-10-07 | 2014-01-30 | David Tsai Ting | Biomarkers of Cancer |
| KR101297336B1 (ko) | 2011-03-30 | 2013-08-14 | 인하대학교 산학협력단 | 점액성 낭성종양 진단 장치 |
| KR101223598B1 (ko) | 2011-04-06 | 2013-01-22 | 인하대학교 산학협력단 | 췌장 상피내 종양 진단 시스템 |
| WO2013063035A1 (en) * | 2011-10-24 | 2013-05-02 | The General Hospital Corporation | Biomarkers of cancer |
| US9822419B2 (en) | 2013-05-20 | 2017-11-21 | Bioventures, Llc | GEP5 model for multiple myeloma |
| GB201319878D0 (en) * | 2013-11-11 | 2013-12-25 | Immunovia Ab | Method, Array and use thereof |
| SG11201607448PA (en) * | 2014-03-11 | 2016-10-28 | Queensland Inst Med Res | Determining cancer agressiveness, prognosis and responsiveness to treatment |
| US10451628B2 (en) * | 2014-05-07 | 2019-10-22 | University Of Utah Research Foundation | Biomarkers and methods for diagnosis of early stage pancreatic ductal adenocarcinoma |
| WO2015200697A1 (en) | 2014-06-25 | 2015-12-30 | The General Hospital Corporation | Targeting human satellite ii (hsatii) |
| EP3198030B1 (en) * | 2014-09-26 | 2020-11-04 | HI-STEM gGmbH Im Deutschen Krebsforschungszentrum DKFZ | Novel methods for sub-typing and treating cancer |
| GB201501930D0 (en) | 2015-02-05 | 2015-03-25 | Univ London Queen Mary | Biomarkers for pancreatic cancer |
| JP2018136122A (ja) * | 2015-05-29 | 2018-08-30 | 国立研究開発法人国立がん研究センター | 膵がんを診断するための血漿バイオマーカーパネル |
| CN105017403B (zh) * | 2015-07-09 | 2018-07-03 | 陈勇 | 胰腺癌相关多肽dap44单克隆抗体的制备及其应用 |
| SG10201913659SA (en) | 2015-10-08 | 2020-03-30 | Oncotherapy Science Inc | Foxm1-derived peptide, and vaccine including same |
| CN111566213B (zh) | 2017-09-11 | 2023-08-04 | 国立大学法人北海道大学 | 癌症治疗药物 |
| EP3508855A1 (en) * | 2018-01-05 | 2019-07-10 | Allianz Pharmascience Ltd | Method for the selection of patients and kit |
| KR102328654B1 (ko) * | 2019-04-17 | 2021-11-19 | 한국원자력의학원 | 암의 예방 또는 치료용 약학 조성물 |
| KR102289278B1 (ko) * | 2019-07-09 | 2021-08-13 | 주식회사 베르티스 | 췌장암 진단용 바이오마커 패널 및 그 용도 |
| GB202010970D0 (en) | 2020-07-16 | 2020-09-02 | Immunovia Ab | Methods, arrays and uses thereof |
| CN115074365B (zh) * | 2022-06-28 | 2023-02-28 | 中国医学科学院北京协和医院 | 靶向GATM基因的sgRNA及其应用 |
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| US5744101A (en) | 1989-06-07 | 1998-04-28 | Affymax Technologies N.V. | Photolabile nucleoside protecting groups |
| WO1998053319A2 (en) | 1997-05-21 | 1998-11-26 | The Johns Hopkins University | Gene expression profiles in normal and cancer cells |
| WO1999031274A2 (en) * | 1997-12-15 | 1999-06-24 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the pancreas |
| US6262249B1 (en) * | 1998-06-23 | 2001-07-17 | Chiron Corporation | Pancreatic cancer genes |
| WO2001064835A2 (en) | 2000-02-28 | 2001-09-07 | Hyseq, Inc. | Novel nucleic acids and polypeptides |
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| US6429302B1 (en) * | 1999-02-02 | 2002-08-06 | Chiron Corporation | Polynucleotides related to pancreatic disease |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| WO2001009318A1 (fr) | 1999-07-29 | 2001-02-08 | Helix Research Institute | Genes associes au cancer du foie |
| EP1661996A1 (en) | 1999-12-01 | 2006-05-31 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
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| US6974667B2 (en) | 2000-06-14 | 2005-12-13 | Gene Logic, Inc. | Gene expression profiles in liver cancer |
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| US20050260639A1 (en) * | 2002-09-30 | 2005-11-24 | Oncotherapy Science, Inc. | Method for diagnosing pancreatic cancer |
| JP2009528507A (ja) * | 2006-03-02 | 2009-08-06 | オンコセラピー・サイエンス株式会社 | Ｒｅｇ４タンパク質を用いて膵癌を診断する方法 |
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- 2003-09-17 EP EP03799106A patent/EP1549771B1/en not_active Expired - Lifetime
- 2003-09-17 WO PCT/JP2003/011817 patent/WO2004031412A2/en active Application Filing
- 2003-09-17 CA CA002500482A patent/CA2500482A1/en not_active Abandoned
- 2003-09-17 EP EP08014535A patent/EP2009117A3/en not_active Withdrawn
- 2003-09-17 AU AU2003263603A patent/AU2003263603A1/en not_active Abandoned
-
2009
- 2009-08-31 US US12/551,372 patent/US7943730B2/en not_active Expired - Fee Related
-
2011
- 2011-04-04 US US13/079,274 patent/US20120028262A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1549771B1 (en) | 2008-12-31 |
| ES2320443T3 (es) | 2009-05-22 |
| US7943730B2 (en) | 2011-05-17 |
| US20060270619A1 (en) | 2006-11-30 |
| AU2003263603A8 (en) | 2004-04-23 |
| CN1703524B (zh) | 2010-04-07 |
| DE60325628D1 (de) | 2009-02-12 |
| EP1556518B1 (en) | 2008-12-31 |
| WO2004031411A3 (en) | 2004-09-30 |
| JP4679149B2 (ja) | 2011-04-27 |
| AU2003260966A8 (en) | 2004-04-23 |
| WO2004031411A2 (en) | 2004-04-15 |
| ATE419391T1 (de) | 2009-01-15 |
| DE60325617D1 (de) | 2009-02-12 |
| ATE419390T1 (de) | 2009-01-15 |
| EP2009117A3 (en) | 2009-03-18 |
| US20100093629A1 (en) | 2010-04-15 |
| US7601826B2 (en) | 2009-10-13 |
| AU2003260966A1 (en) | 2004-04-23 |
| EP1556518A2 (en) | 2005-07-27 |
| EP2009117A2 (en) | 2008-12-31 |
| EP1549771A2 (en) | 2005-07-06 |
| CN1703524A (zh) | 2005-11-30 |
| CA2500482A1 (en) | 2004-04-15 |
| JP2006500948A (ja) | 2006-01-12 |
| US20120028262A1 (en) | 2012-02-02 |
| AU2003263603A1 (en) | 2004-04-23 |
| WO2004031412A2 (en) | 2004-04-15 |
| WO2004031412A3 (en) | 2004-07-15 |
| JP2006500947A (ja) | 2006-01-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |