CA2486362A1 - Novel recombinant anticoagulant proteins - Google Patents

Info

Publication number

CA2486362A1

CA2486362A1 CA002486362A CA2486362A CA2486362A1 CA 2486362 A1 CA2486362 A1 CA 2486362A1 CA 002486362 A CA002486362 A CA 002486362A CA 2486362 A CA2486362 A CA 2486362A CA 2486362 A1 CA2486362 A1 CA 2486362A1

Authority

CA

Canada

Prior art keywords

anv

seq

recombinant

leu

ala

Prior art date

2002-06-06

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Abandoned

Links

• Espacenet
• Global Dossier
• CIPO
• Discuss

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• 108090000672 Annexin A5 Proteins 0.000 claims abstract description 137
• 102000004121 Annexin A5 Human genes 0.000 claims abstract description 133
• 108090000623 proteins and genes Proteins 0.000 claims abstract description 64
• 230000004927 fusion Effects 0.000 claims abstract description 39
• 238000000034 method Methods 0.000 claims abstract description 32
• 102000004169 proteins and genes Human genes 0.000 claims abstract description 27
• 239000000137 peptide hydrolase inhibitor Substances 0.000 claims abstract description 19
• 230000023555 blood coagulation Effects 0.000 claims abstract description 13
• 102100030951 Tissue factor pathway inhibitor Human genes 0.000 claims description 52
• 108010013555 lipoprotein-associated coagulation inhibitor Proteins 0.000 claims description 52
• 239000003146 anticoagulant agent Substances 0.000 claims description 29
• 108700019335 ANV-6L15 Proteins 0.000 claims description 27
• 210000004027 cell Anatomy 0.000 claims description 27
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• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 8
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• UGVQELHRNUDMAA-BYPYZUCNSA-N Gly-Ala-Gly Chemical compound [NH3+]CC(=O)N[C@@H](C)C(=O)NCC([O-])=O UGVQELHRNUDMAA-BYPYZUCNSA-N 0.000 description 8
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• 239000001110 calcium chloride Substances 0.000 description 8
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