CA2477849A1 - Method for producing riboflavin - Google Patents

Method for producing riboflavin Download PDF

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Publication number
CA2477849A1
CA2477849A1 CA002477849A CA2477849A CA2477849A1 CA 2477849 A1 CA2477849 A1 CA 2477849A1 CA 002477849 A CA002477849 A CA 002477849A CA 2477849 A CA2477849 A CA 2477849A CA 2477849 A1 CA2477849 A1 CA 2477849A1
Authority
CA
Canada
Prior art keywords
gene
transcription terminator
seq
riboflavin
organism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002477849A
Other languages
English (en)
French (fr)
Inventor
Henning Althoefer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2477849A1 publication Critical patent/CA2477849A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
CA002477849A 2002-03-02 2003-02-28 Method for producing riboflavin Abandoned CA2477849A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10209363.6 2002-03-02
DE10209363A DE10209363A1 (de) 2002-03-02 2002-03-02 Verfahren zur Herstellung von Riboflavin
PCT/EP2003/002101 WO2003074721A2 (de) 2002-03-02 2003-02-28 Verfahren zur herstellung von riboflavin

Publications (1)

Publication Number Publication Date
CA2477849A1 true CA2477849A1 (en) 2003-09-12

Family

ID=27740616

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002477849A Abandoned CA2477849A1 (en) 2002-03-02 2003-02-28 Method for producing riboflavin

Country Status (8)

Country Link
EP (1) EP1483398A2 (zh)
JP (1) JP2005527200A (zh)
KR (1) KR20040096643A (zh)
CN (1) CN1639353A (zh)
AU (1) AU2003206964A1 (zh)
CA (1) CA2477849A1 (zh)
DE (1) DE10209363A1 (zh)
WO (1) WO2003074721A2 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4520219B2 (ja) * 2004-05-28 2010-08-04 協和発酵バイオ株式会社 ５−アミノレブリン酸の製造法
KR101335853B1 (ko) * 2011-12-01 2013-12-02 씨제이제일제당 (주) Ｌ-아미노산 및 리보플라빈을 동시에 생산하는 미생물 및 이를 이용한 ｌ-아미노산 및 리보플라빈을 생산하는 방법
CN106434819A (zh) * 2016-12-22 2017-02-22 广济药业（孟州）有限公司 一种提高枯草芽孢杆菌发酵生产核黄素的产量的方法
CN110964769B (zh) * 2019-11-29 2022-11-11 河南巨龙生物工程股份有限公司 一种提高枯草芽孢杆菌发酵生产核黄素收率的方法
CN113801910A (zh) * 2021-08-30 2021-12-17 湖北广济药业股份有限公司 一种纯天然核黄素的制备方法
CN113755551A (zh) * 2021-09-30 2021-12-07 天津科技大学 一种提高核黄素产量的发酵方法
CN113817654B (zh) * 2021-11-08 2023-06-20 通辽梅花生物科技有限公司 一种生产核黄素的发酵培养基及发酵方法
KR20230168477A (ko) * 2022-06-07 2023-12-14 씨제이제일제당 (주) 리보플라빈 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 리보플라빈을 생산하는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2216010T3 (es) * 1994-03-25 2004-10-16 Basf Aktiengesellschaft Biosintesis de riboflavina en hongos.
JPH1084978A (ja) * 1996-07-24 1998-04-07 F Hoffmann La Roche Ag 改良されたリボフラビン生産
DE19823834A1 (de) * 1998-05-28 1999-12-02 Basf Ag Genetisches Verfahren zur Herstellung von Riboflavin

Also Published As

Publication number Publication date
AU2003206964A8 (en) 2003-09-16
EP1483398A2 (de) 2004-12-08
KR20040096643A (ko) 2004-11-16
WO2003074721A2 (de) 2003-09-12
CN1639353A (zh) 2005-07-13
AU2003206964A1 (en) 2003-09-16
DE10209363A1 (de) 2003-09-11
JP2005527200A (ja) 2005-09-15
WO2003074721A3 (de) 2003-12-24

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Legal Events

Date Code Title Description
FZDE Discontinued