CA2472280C - Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of bioreactive recombinants - Google Patents

Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of bioreactive recombinants Download PDF

Info

Publication number
CA2472280C
CA2472280C CA2472280A CA2472280A CA2472280C CA 2472280 C CA2472280 C CA 2472280C CA 2472280 A CA2472280 A CA 2472280A CA 2472280 A CA2472280 A CA 2472280A CA 2472280 C CA2472280 C CA 2472280C
Authority
CA
Canada
Prior art keywords
cyplasin
cells
nucleic acid
protein
leu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2472280A
Other languages
English (en)
French (fr)
Other versions
CA2472280A1 (en
Inventor
Christian Petzelt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioxen Ltd
Original Assignee
Cyplasin Biomedical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cyplasin Biomedical Ltd filed Critical Cyplasin Biomedical Ltd
Publication of CA2472280A1 publication Critical patent/CA2472280A1/en
Application granted granted Critical
Publication of CA2472280C publication Critical patent/CA2472280C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/855Proteins from animals other than mammals or birds
    • Y10S530/857Fish; fish eggs; shell fish; crustacea

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA2472280A 2002-01-07 2002-12-18 Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of bioreactive recombinants Expired - Fee Related CA2472280C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP02000388 2002-01-07
EP02000388.5 2002-01-07
EP02019914A EP1325929B1 (en) 2002-01-07 2002-09-04 Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants
EP02019914.7 2002-09-04
PCT/EP2002/014511 WO2003057726A1 (en) 2002-01-07 2002-12-18 Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants

Publications (2)

Publication Number Publication Date
CA2472280A1 CA2472280A1 (en) 2003-07-17
CA2472280C true CA2472280C (en) 2010-04-13

Family

ID=26077563

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2472280A Expired - Fee Related CA2472280C (en) 2002-01-07 2002-12-18 Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of bioreactive recombinants

Country Status (7)

Country Link
US (1) US7271242B2 (https=)
EP (1) EP1325929B1 (https=)
JP (1) JP2005527194A (https=)
CN (1) CN1622956A (https=)
AU (1) AU2002361168B2 (https=)
CA (1) CA2472280C (https=)
WO (1) WO2003057726A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1585761B1 (en) 2003-01-20 2013-08-21 Thomas Rudel L-amino acid oxidase with cytotoxic activity from aplysia punctata
DE102004062386B4 (de) 2003-12-24 2010-06-24 Food Industry Research And Development Institute Monacolin K-Biosynthese-Gene
CN106868198B (zh) * 2017-04-25 2020-09-18 扬州宏盛水产科技有限公司 一种同时检测鲇形目鱼类四种致病菌的多重pcr引物组及监测方法

Also Published As

Publication number Publication date
CN1622956A (zh) 2005-06-01
EP1325929A3 (en) 2003-07-16
AU2002361168B2 (en) 2008-05-08
JP2005527194A (ja) 2005-09-15
EP1325929A2 (en) 2003-07-09
US20050277763A1 (en) 2005-12-15
US7271242B2 (en) 2007-09-18
EP1325929B1 (en) 2009-03-25
AU2002361168A1 (en) 2003-07-24
CA2472280A1 (en) 2003-07-17
WO2003057726A1 (en) 2003-07-17

Similar Documents

Publication Publication Date Title
JP4411330B2 (ja) 腫瘍壊死因子関連リガンド
EP0775711B1 (en) Peptide having antithrombotic activity and process for producing the same
KR101365538B1 (ko) 변형된 포어 형성 단백질을 이용하여 양성 전립선 비대를치료하거나 예방하는 방법
Jung et al. Purification and cloning of an apoptosis-inducing protein derived from fish infected with Anisakis simplex, a causative nematode of human anisakiasis
CA2200980C (en) Mammalian receptors for modified low-density lipoprotein
US5831030A (en) Antibodies specific for megakaryocyte differentiation factor
KR100629185B1 (ko) 인간 리조포스파티드산 수용체 물질 및 그 용도
WO1993025685A1 (en) Cloning and characterization of the cell death genes ced-3 and ced-4
US6368845B1 (en) Polypeptides having L-asparaginase activity
CA2472280C (en) Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of bioreactive recombinants
US5856444A (en) Thrombocytopoiesis stimulating factor
Petzelt et al. Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning, and expression of bioactive recombinants in insect cells
EP1363942A2 (de) Polypeptide eines hdm2-protein spezifischen murinen alpha/beta t-zell rezeptors, diese kodierende nukleinsüren und deren verwendung
HK1058678A (en) Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of bioreactive recombinants
JP2003517311A (ja) カスパーゼにより誘導されるアポトーシスのための組成物および方法
KR100934594B1 (ko) 신규 폴리펩티드 및 그것을 코드하는 유전자
HK1077584A (en) Cytotoxic cyplasin of the sea hare, aplysia punctata, cdna cloning and expression of the bioreactive recombinants
US6762296B2 (en) Antitumor protein and corresponding gene sequence isolated from matsutake mushrooms
WO2008118100A1 (en) Method of enhancing migration of neural precursor cells
Yamamoto et al. Strong expression of the calreticulin gene in the liver of Rana rugosa tadpoles, but not adult frogs
CN100358917C (zh) 肿瘤标志物及其用途
JP3621883B2 (ja) ウイルスがコードするセマフォリンタンパク質受容体dnaおよびポリペプチド
WO1997000951A1 (fr) Adn codant pour un inhibiteur du complement, d'origine porcine
CN114381445A (zh) 具有杀灭疟原虫作用的沙雷氏菌脂肪酶及其编码基因
CN100999727A (zh) 肿瘤和免疫相关的调控因子Caspase-10/G

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed

Effective date: 20141218