AU2002361168B2 - Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants - Google Patents
Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants Download PDFInfo
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- 230000000903 blocking effect Effects 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
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- DNJIEGIFACGWOD-UHFFFAOYSA-N ethyl mercaptane Natural products CCS DNJIEGIFACGWOD-UHFFFAOYSA-N 0.000 description 1
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- JPXMTWWFLBLUCD-UHFFFAOYSA-N nitro blue tetrazolium(2+) Chemical compound COC1=CC(C=2C=C(OC)C(=CC=2)[N+]=2N(N=C(N=2)C=2C=CC=CC=2)C=2C=CC(=CC=2)[N+]([O-])=O)=CC=C1[N+]1=NC(C=2C=CC=CC=2)=NN1C1=CC=C([N+]([O-])=O)C=C1 JPXMTWWFLBLUCD-UHFFFAOYSA-N 0.000 description 1
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- CWCMIVBLVUHDHK-ZSNHEYEWSA-N phleomycin D1 Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC[C@@H](N=1)C=1SC=C(N=1)C(=O)NCCCCNC(N)=N)[C@@H](O[C@H]1[C@H]([C@@H](O)[C@H](O)[C@H](CO)O1)O[C@@H]1[C@H]([C@@H](OC(N)=O)[C@H](O)[C@@H](CO)O1)O)C=1N=CNC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C CWCMIVBLVUHDHK-ZSNHEYEWSA-N 0.000 description 1
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- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/855—Proteins from animals other than mammals or birds
- Y10S530/857—Fish; fish eggs; shell fish; crustacea
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02000388 | 2002-01-07 | ||
| EP02000388.5 | 2002-01-07 | ||
| EP02019914A EP1325929B1 (en) | 2002-01-07 | 2002-09-04 | Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants |
| EP02019914.7 | 2002-09-04 | ||
| PCT/EP2002/014511 WO2003057726A1 (en) | 2002-01-07 | 2002-12-18 | Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2002361168A1 AU2002361168A1 (en) | 2003-07-24 |
| AU2002361168B2 true AU2002361168B2 (en) | 2008-05-08 |
Family
ID=26077563
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2002361168A Ceased AU2002361168B2 (en) | 2002-01-07 | 2002-12-18 | Cytotoxic cyplasin of the sea hare, Aplysia punctata, cDNA cloning and expression of bioreactive recombinants |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7271242B2 (https=) |
| EP (1) | EP1325929B1 (https=) |
| JP (1) | JP2005527194A (https=) |
| CN (1) | CN1622956A (https=) |
| AU (1) | AU2002361168B2 (https=) |
| CA (1) | CA2472280C (https=) |
| WO (1) | WO2003057726A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1585761B1 (en) | 2003-01-20 | 2013-08-21 | Thomas Rudel | L-amino acid oxidase with cytotoxic activity from aplysia punctata |
| DE102004062386B4 (de) | 2003-12-24 | 2010-06-24 | Food Industry Research And Development Institute | Monacolin K-Biosynthese-Gene |
| CN106868198B (zh) * | 2017-04-25 | 2020-09-18 | 扬州宏盛水产科技有限公司 | 一种同时检测鲇形目鱼类四种致病菌的多重pcr引物组及监测方法 |
-
2002
- 2002-09-04 EP EP02019914A patent/EP1325929B1/en not_active Expired - Lifetime
- 2002-12-18 CA CA2472280A patent/CA2472280C/en not_active Expired - Fee Related
- 2002-12-18 JP JP2003558040A patent/JP2005527194A/ja active Pending
- 2002-12-18 CN CNA028284690A patent/CN1622956A/zh active Pending
- 2002-12-18 WO PCT/EP2002/014511 patent/WO2003057726A1/en not_active Ceased
- 2002-12-18 AU AU2002361168A patent/AU2002361168B2/en not_active Ceased
- 2002-12-18 US US10/501,098 patent/US7271242B2/en not_active Expired - Fee Related
Non-Patent Citations (2)
| Title |
|---|
| Keifer, P. et al. (1994) EMBO Journal 13(17): 4126-4136 * |
| Sturley, S.L. et al. (1994) J. of Biol. Chem. 269(34): 21670-21675 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1622956A (zh) | 2005-06-01 |
| EP1325929A3 (en) | 2003-07-16 |
| JP2005527194A (ja) | 2005-09-15 |
| EP1325929A2 (en) | 2003-07-09 |
| US20050277763A1 (en) | 2005-12-15 |
| US7271242B2 (en) | 2007-09-18 |
| CA2472280C (en) | 2010-04-13 |
| EP1325929B1 (en) | 2009-03-25 |
| AU2002361168A1 (en) | 2003-07-24 |
| CA2472280A1 (en) | 2003-07-17 |
| WO2003057726A1 (en) | 2003-07-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1 | Assignment before grant (sect. 113) |
Owner name: CYPLASIN BIOMEDICAL, LTD. Free format text: FORMER APPLICANT(S): PETZELT, CHRISTIAN |
|
| FGA | Letters patent sealed or granted (standard patent) | ||
| PC | Assignment registered |
Owner name: BIOXEN LTD. Free format text: FORMER OWNER WAS: CYPLASIN BIOMEDICAL, LTD. |
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| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |