CA2461572C - Polycyclic compounds having anti-tumor activity - Google Patents
Polycyclic compounds having anti-tumor activity Download PDFInfo
- Publication number
- CA2461572C CA2461572C CA2461572A CA2461572A CA2461572C CA 2461572 C CA2461572 C CA 2461572C CA 2461572 A CA2461572 A CA 2461572A CA 2461572 A CA2461572 A CA 2461572A CA 2461572 C CA2461572 C CA 2461572C
- Authority
- CA
- Canada
- Prior art keywords
- diaza
- benzo
- fluoren
- dimethylamino
- ethylamino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01123908 | 2001-10-05 | ||
| EP01123908.4 | 2001-10-05 | ||
| PCT/EP2002/010722 WO2003031444A1 (en) | 2001-10-05 | 2002-09-25 | Polycyclic compounds having anti-tumor activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2461572A1 CA2461572A1 (en) | 2003-04-17 |
| CA2461572C true CA2461572C (en) | 2011-02-15 |
Family
ID=8178868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2461572A Expired - Fee Related CA2461572C (en) | 2001-10-05 | 2002-09-25 | Polycyclic compounds having anti-tumor activity |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US6680326B2 (OSRAM) |
| EP (1) | EP1436293B1 (OSRAM) |
| JP (1) | JP4369229B2 (OSRAM) |
| KR (1) | KR100676114B1 (OSRAM) |
| CN (1) | CN1284781C (OSRAM) |
| AR (1) | AR037327A1 (OSRAM) |
| AT (1) | ATE316971T1 (OSRAM) |
| AU (1) | AU2002342752B2 (OSRAM) |
| BR (1) | BR0213122A (OSRAM) |
| CA (1) | CA2461572C (OSRAM) |
| DE (1) | DE60209029T2 (OSRAM) |
| ES (1) | ES2256552T3 (OSRAM) |
| MX (1) | MXPA04003173A (OSRAM) |
| PL (1) | PL370530A1 (OSRAM) |
| RU (1) | RU2315050C2 (OSRAM) |
| WO (1) | WO2003031444A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6946472B2 (en) * | 2002-04-30 | 2005-09-20 | Hoffman-La Roche Inc. | Polycyclic compounds exhibiting anti-tumor activities |
| US20060189893A1 (en) * | 2005-01-06 | 2006-08-24 | Diamics, Inc. | Systems and methods for detecting abnormal cells |
| US20060161076A1 (en) * | 2005-01-06 | 2006-07-20 | Diamics, Inc. | Systems and methods for collection of cell clusters |
| CN103204781B (zh) * | 2013-03-14 | 2015-04-01 | 武汉大学 | 2,7–二取代芴酮衍生物及其制备方法与应用 |
| CN110448555B (zh) * | 2019-09-10 | 2020-10-23 | 河南省人民医院 | 多环化合物在制备抗肿瘤药物中的应用及抗肿瘤药物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW440562B (en) * | 1994-05-20 | 2001-06-16 | Taiho Pharmaceutical Co Ltd | Condensed-indan derivative and pharmaceutically acceptable salts thereof |
| WO1998045272A1 (en) | 1997-04-07 | 1998-10-15 | Latrobe University | Topoisomerase inhibitors |
| FR2801309B1 (fr) * | 1999-11-18 | 2002-01-04 | Adir | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2002
- 2002-09-25 CA CA2461572A patent/CA2461572C/en not_active Expired - Fee Related
- 2002-09-25 EP EP02779413A patent/EP1436293B1/en not_active Expired - Lifetime
- 2002-09-25 US US10/254,951 patent/US6680326B2/en not_active Expired - Fee Related
- 2002-09-25 AU AU2002342752A patent/AU2002342752B2/en not_active Ceased
- 2002-09-25 AT AT02779413T patent/ATE316971T1/de active
- 2002-09-25 WO PCT/EP2002/010722 patent/WO2003031444A1/en not_active Ceased
- 2002-09-25 BR BR0213122-6A patent/BR0213122A/pt not_active IP Right Cessation
- 2002-09-25 ES ES02779413T patent/ES2256552T3/es not_active Expired - Lifetime
- 2002-09-25 JP JP2003534427A patent/JP4369229B2/ja not_active Expired - Fee Related
- 2002-09-25 CN CNB028197712A patent/CN1284781C/zh not_active Expired - Fee Related
- 2002-09-25 MX MXPA04003173A patent/MXPA04003173A/es active IP Right Grant
- 2002-09-25 PL PL02370530A patent/PL370530A1/xx not_active Application Discontinuation
- 2002-09-25 RU RU2004114245/04A patent/RU2315050C2/ru not_active IP Right Cessation
- 2002-09-25 DE DE60209029T patent/DE60209029T2/de not_active Expired - Lifetime
- 2002-09-25 KR KR1020047004899A patent/KR100676114B1/ko not_active Expired - Fee Related
- 2002-10-02 AR ARP020103723A patent/AR037327A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003031444A1 (en) | 2003-04-17 |
| PL370530A1 (en) | 2005-05-30 |
| DE60209029T2 (de) | 2006-09-28 |
| EP1436293B1 (en) | 2006-02-01 |
| US20030073691A1 (en) | 2003-04-17 |
| US6680326B2 (en) | 2004-01-20 |
| MXPA04003173A (es) | 2004-07-27 |
| EP1436293A1 (en) | 2004-07-14 |
| CN1284781C (zh) | 2006-11-15 |
| AU2002342752B2 (en) | 2007-11-15 |
| JP2005504846A (ja) | 2005-02-17 |
| KR100676114B1 (ko) | 2007-02-02 |
| CA2461572A1 (en) | 2003-04-17 |
| CN1610681A (zh) | 2005-04-27 |
| JP4369229B2 (ja) | 2009-11-18 |
| BR0213122A (pt) | 2004-09-21 |
| ATE316971T1 (de) | 2006-02-15 |
| KR20040048926A (ko) | 2004-06-10 |
| RU2004114245A (ru) | 2005-06-27 |
| ES2256552T3 (es) | 2006-07-16 |
| RU2315050C2 (ru) | 2008-01-20 |
| AR037327A1 (es) | 2004-11-03 |
| DE60209029D1 (de) | 2006-04-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| WO2024041621A1 (en) | K-ras mutant protein inhibitors | |
| CN103588792B (zh) | 吡啶并嘧啶或嘧啶并嘧啶类化合物、其制备方法、药物组合物及其用途 | |
| JP2022517723A (ja) | Ｃｄｋ阻害剤としての大環状化合物、その製造方法及びその医薬品における応用 | |
| GB2449293A (en) | Compounds having Hsp90 inhibitory activity | |
| JPH11504922A (ja) | 蛋白チロシンキナーゼ媒介細胞増殖を抑制するためのピリド［２，３−ｄ］ピリミジン類 | |
| HUT67431A (en) | Vinylen-or methylen-azaindol derivatives, pharmaceutical compositions containing the same and process for their production | |
| WO2013178075A1 (zh) | N-芳基不饱和稠环叔胺类化合物及其制备方法和抗肿瘤应用 | |
| HU214584B (hu) | Eljárás dibenz[b,f][1,4]oxazepin-11(10H)-onok és az ezeket tartalmazó gyógyszerkészítmények előállítására | |
| CA2461572C (en) | Polycyclic compounds having anti-tumor activity | |
| JP2025516222A (ja) | 脱ユビキチン化酵素阻害剤及びその応用 | |
| CN114031623B (zh) | 一种c14位氨基取代粉防己碱衍生物及其制备和应用 | |
| CN117645598A (zh) | 氮杂二并多元稠环化合物及其药物组合物和应用 | |
| AU2002342752A1 (en) | Polycyclic compounds having anti-tumor activity | |
| US9944641B2 (en) | Isoquinolinone derivatives useful in the treatment of cancer | |
| RU2130937C1 (ru) | 2-аминоалкил-5-аминоалкиламинозамещенные изохиноиндазол-6-(2н)-оны, способ их получения, фармацевтическая композиция и способ лечения опухоли | |
| Mastalarz et al. | Synthesis and Cytostatic Properties of Some 6H‐Indolo [2, 3‐b][1, 8] naphthyridine Derivatives | |
| EP1636234A1 (en) | Imidazotriazinone derivatives as pde 7 (phosphodiesterase 7) inhibitors | |
| EP3441387A1 (en) | Pi3k inhibitor, and pharmaceutically acceptable salt, polycrystalline form, and application thereof | |
| US6946472B2 (en) | Polycyclic compounds exhibiting anti-tumor activities | |
| CN106496232B (zh) | 一种具有抗肿瘤活性的1-(2-四氢吡喃)-1H-吡唑并[3,4-d]嘧啶类化合物及其制备方法 | |
| WO2019149128A1 (zh) | 作为抗肿瘤药物的5-氯-2,4-嘧啶衍生物 | |
| WO1999059996A1 (en) | Antitumour 1,5-diazaanthraquinones | |
| KR101812266B1 (ko) | 4-((2-아크릴아미도페닐)아미노)티에노[3,2-d]피리미딘-7-카복스아미드 유도체 및 그의 약학적 활용 | |
| WO2025082225A1 (en) | Benzo [c] [1, 2] oxaborol-1 (3h) -ol derivatives as shp2 inhibitors, compositions and methods thereof | |
| WO2022166468A1 (zh) | Bruton's酪氨酸激酶抑制剂及其应用 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20140925 |