MXPA04003173A - Compuestos policiclicos que tienen actividad antituoral. - Google Patents

Compuestos policiclicos que tienen actividad antituoral.

Info

Publication number
MXPA04003173A
MXPA04003173A MXPA04003173A MXPA04003173A MXPA04003173A MX PA04003173 A MXPA04003173 A MX PA04003173A MX PA04003173 A MXPA04003173 A MX PA04003173A MX PA04003173 A MXPA04003173 A MX PA04003173A MX PA04003173 A MXPA04003173 A MX PA04003173A
Authority
MX
Mexico
Prior art keywords
polycyclic compounds
tumor activity
compounds
ring
tumor
Prior art date
Application number
MXPA04003173A
Other languages
English (en)
Inventor
Sakata Kiyoaki
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MXPA04003173A publication Critical patent/MXPA04003173A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nuevos compuestos policiclicos de la formula (I), (ver formula (1)en la cual R1, R2, R3, R4, R5, R6, R7, anillo A, anillos B, X, Y y Z son tal como se definieron en las reivindicaciones y descripcion, asi como tambien sales farmaceuticamente aceptables de los mismos. Los compuestos tienen actividad antitumoral y son utiles para el tratamiento de tumores.
MXPA04003173A 2001-10-05 2002-09-25 Compuestos policiclicos que tienen actividad antituoral. MXPA04003173A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01123908 2001-10-05
PCT/EP2002/010722 WO2003031444A1 (en) 2001-10-05 2002-09-25 Polycyclic compounds having anti-tumor activity

Publications (1)

Publication Number Publication Date
MXPA04003173A true MXPA04003173A (es) 2004-07-27

Family

ID=8178868

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04003173A MXPA04003173A (es) 2001-10-05 2002-09-25 Compuestos policiclicos que tienen actividad antituoral.

Country Status (16)

Country Link
US (1) US6680326B2 (es)
EP (1) EP1436293B1 (es)
JP (1) JP4369229B2 (es)
KR (1) KR100676114B1 (es)
CN (1) CN1284781C (es)
AR (1) AR037327A1 (es)
AT (1) ATE316971T1 (es)
AU (1) AU2002342752B2 (es)
BR (1) BR0213122A (es)
CA (1) CA2461572C (es)
DE (1) DE60209029T2 (es)
ES (1) ES2256552T3 (es)
MX (1) MXPA04003173A (es)
PL (1) PL370530A1 (es)
RU (1) RU2315050C2 (es)
WO (1) WO2003031444A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946472B2 (en) * 2002-04-30 2005-09-20 Hoffman-La Roche Inc. Polycyclic compounds exhibiting anti-tumor activities
US20060189893A1 (en) * 2005-01-06 2006-08-24 Diamics, Inc. Systems and methods for detecting abnormal cells
US20060161076A1 (en) * 2005-01-06 2006-07-20 Diamics, Inc. Systems and methods for collection of cell clusters
CN103204781B (zh) * 2013-03-14 2015-04-01 武汉大学 2,7–二取代芴酮衍生物及其制备方法与应用
CN110448555B (zh) * 2019-09-10 2020-10-23 河南省人民医院 多环化合物在制备抗肿瘤药物中的应用及抗肿瘤药物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW440562B (en) * 1994-05-20 2001-06-16 Taiho Pharmaceutical Co Ltd Condensed-indan derivative and pharmaceutically acceptable salts thereof
WO1998045272A1 (en) 1997-04-07 1998-10-15 Latrobe University Topoisomerase inhibitors
FR2801309B1 (fr) * 1999-11-18 2002-01-04 Adir Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
AU2002342752B2 (en) 2007-11-15
DE60209029D1 (de) 2006-04-13
RU2004114245A (ru) 2005-06-27
EP1436293A1 (en) 2004-07-14
KR100676114B1 (ko) 2007-02-02
RU2315050C2 (ru) 2008-01-20
ES2256552T3 (es) 2006-07-16
CN1610681A (zh) 2005-04-27
WO2003031444A1 (en) 2003-04-17
AR037327A1 (es) 2004-11-03
CA2461572C (en) 2011-02-15
ATE316971T1 (de) 2006-02-15
CN1284781C (zh) 2006-11-15
EP1436293B1 (en) 2006-02-01
CA2461572A1 (en) 2003-04-17
DE60209029T2 (de) 2006-09-28
JP2005504846A (ja) 2005-02-17
PL370530A1 (en) 2005-05-30
BR0213122A (pt) 2004-09-21
JP4369229B2 (ja) 2009-11-18
US6680326B2 (en) 2004-01-20
US20030073691A1 (en) 2003-04-17
KR20040048926A (ko) 2004-06-10

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Legal Events

Date Code Title Description
FG Grant or registration