RU2315050C2 - Полициклические соединения, обладающие противоопухолевой активностью - Google Patents

Полициклические соединения, обладающие противоопухолевой активностью Download PDF

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Publication number
RU2315050C2
RU2315050C2 RU2004114245/04A RU2004114245A RU2315050C2 RU 2315050 C2 RU2315050 C2 RU 2315050C2 RU 2004114245/04 A RU2004114245/04 A RU 2004114245/04A RU 2004114245 A RU2004114245 A RU 2004114245A RU 2315050 C2 RU2315050 C2 RU 2315050C2
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RU
Russia
Prior art keywords
fluoren
diazabenzo
dimethylaminoethylamino
hydroxy
polycyclic compounds
Prior art date
Application number
RU2004114245/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2004114245A (ru
Inventor
Тсунехиса АОЯМА
Кеничи Кавасаки
Мияко Масубучи
Татсуо ОХТСУКА
Киёаки САКАТА
Original Assignee
Ф.Хоффманн-Ля Рош Аг
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Publication date
Application filed by Ф.Хоффманн-Ля Рош Аг filed Critical Ф.Хоффманн-Ля Рош Аг
Publication of RU2004114245A publication Critical patent/RU2004114245A/ru
Application granted granted Critical
Publication of RU2315050C2 publication Critical patent/RU2315050C2/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU2004114245/04A 2001-10-05 2002-09-25 Полициклические соединения, обладающие противоопухолевой активностью RU2315050C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01123908 2001-10-05
EP01123908.4 2001-10-05

Publications (2)

Publication Number Publication Date
RU2004114245A RU2004114245A (ru) 2005-06-27
RU2315050C2 true RU2315050C2 (ru) 2008-01-20

Family

ID=8178868

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004114245/04A RU2315050C2 (ru) 2001-10-05 2002-09-25 Полициклические соединения, обладающие противоопухолевой активностью

Country Status (16)

Country Link
US (1) US6680326B2 (OSRAM)
EP (1) EP1436293B1 (OSRAM)
JP (1) JP4369229B2 (OSRAM)
KR (1) KR100676114B1 (OSRAM)
CN (1) CN1284781C (OSRAM)
AR (1) AR037327A1 (OSRAM)
AT (1) ATE316971T1 (OSRAM)
AU (1) AU2002342752B2 (OSRAM)
BR (1) BR0213122A (OSRAM)
CA (1) CA2461572C (OSRAM)
DE (1) DE60209029T2 (OSRAM)
ES (1) ES2256552T3 (OSRAM)
MX (1) MXPA04003173A (OSRAM)
PL (1) PL370530A1 (OSRAM)
RU (1) RU2315050C2 (OSRAM)
WO (1) WO2003031444A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6946472B2 (en) * 2002-04-30 2005-09-20 Hoffman-La Roche Inc. Polycyclic compounds exhibiting anti-tumor activities
US20060189893A1 (en) * 2005-01-06 2006-08-24 Diamics, Inc. Systems and methods for detecting abnormal cells
US20060161076A1 (en) * 2005-01-06 2006-07-20 Diamics, Inc. Systems and methods for collection of cell clusters
CN103204781B (zh) * 2013-03-14 2015-04-01 武汉大学 2,7–二取代芴酮衍生物及其制备方法与应用
CN110448555B (zh) * 2019-09-10 2020-10-23 河南省人民医院 多环化合物在制备抗肿瘤药物中的应用及抗肿瘤药物

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2124017C1 (ru) * 1994-05-20 1998-12-27 Тайхо Фармасьютикал Ко., Лтд Конденсированные производные индана, способ их получения и композиция, обладающая противоопухолевым действием

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998045272A1 (en) 1997-04-07 1998-10-15 Latrobe University Topoisomerase inhibitors
FR2801309B1 (fr) * 1999-11-18 2002-01-04 Adir Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2124017C1 (ru) * 1994-05-20 1998-12-27 Тайхо Фармасьютикал Ко., Лтд Конденсированные производные индана, способ их получения и композиция, обладающая противоопухолевым действием

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
формула изобретения, реферат, таблица 1. ЕР 1101765 А2, с.3, строка 16; с.4, строка 25. WO 98/48272 А1, с.4, строка 30; с.6, строка 4; с.8, строки 8-23. *

Also Published As

Publication number Publication date
WO2003031444A1 (en) 2003-04-17
PL370530A1 (en) 2005-05-30
DE60209029T2 (de) 2006-09-28
EP1436293B1 (en) 2006-02-01
US20030073691A1 (en) 2003-04-17
US6680326B2 (en) 2004-01-20
MXPA04003173A (es) 2004-07-27
EP1436293A1 (en) 2004-07-14
CN1284781C (zh) 2006-11-15
CA2461572C (en) 2011-02-15
AU2002342752B2 (en) 2007-11-15
JP2005504846A (ja) 2005-02-17
KR100676114B1 (ko) 2007-02-02
CA2461572A1 (en) 2003-04-17
CN1610681A (zh) 2005-04-27
JP4369229B2 (ja) 2009-11-18
BR0213122A (pt) 2004-09-21
ATE316971T1 (de) 2006-02-15
KR20040048926A (ko) 2004-06-10
RU2004114245A (ru) 2005-06-27
ES2256552T3 (es) 2006-07-16
AR037327A1 (es) 2004-11-03
DE60209029D1 (de) 2006-04-13

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Effective date: 20130926