CA2458084A1 - Nouvelle methode de synthese de l'octreotide - Google Patents
Nouvelle methode de synthese de l'octreotide Download PDFInfo
- Publication number
- CA2458084A1 CA2458084A1 CA002458084A CA2458084A CA2458084A1 CA 2458084 A1 CA2458084 A1 CA 2458084A1 CA 002458084 A CA002458084 A CA 002458084A CA 2458084 A CA2458084 A CA 2458084A CA 2458084 A1 CA2458084 A1 CA 2458084A1
- Authority
- CA
- Canada
- Prior art keywords
- boc
- phe
- cys
- trt
- thr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002458084A CA2458084A1 (fr) | 2004-03-12 | 2004-03-12 | Nouvelle methode de synthese de l'octreotide |
PCT/CA2005/000378 WO2005087794A1 (fr) | 2004-03-12 | 2005-03-14 | Procede de synthese d'octreotide |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002458084A CA2458084A1 (fr) | 2004-03-12 | 2004-03-12 | Nouvelle methode de synthese de l'octreotide |
Publications (1)
Publication Number | Publication Date |
---|---|
CA2458084A1 true CA2458084A1 (fr) | 2005-09-12 |
Family
ID=34975525
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002458084A Abandoned CA2458084A1 (fr) | 2004-03-12 | 2004-03-12 | Nouvelle methode de synthese de l'octreotide |
Country Status (2)
Country | Link |
---|---|
CA (1) | CA2458084A1 (fr) |
WO (1) | WO2005087794A1 (fr) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013132505A1 (fr) | 2012-03-09 | 2013-09-12 | Natco Pharma Limited | Procédé amélioré pour la préparation d'octréotide par une synthèse peptidique en phase solution |
US10087221B2 (en) | 2013-03-21 | 2018-10-02 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010089757A2 (fr) | 2008-11-07 | 2010-08-12 | Usv Limited | Procédé amélioré de synthèse d'un octapeptide cyclique |
CA2748873C (fr) | 2009-01-23 | 2017-09-12 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Methodes et compositions basees sur la proteine shiga-toxine de type 2 |
WO2013046233A2 (fr) | 2011-09-30 | 2013-04-04 | Mylan Laboratories Ltd | Procédé de préparation d'acétate d'octréotide |
US9388212B2 (en) | 2013-02-21 | 2016-07-12 | Chemical & Biopharmaceutical Laboratories Of Patras S.A. | Solid phase peptide synthesis via side chain attachment |
CN102850438B (zh) * | 2012-09-19 | 2014-11-05 | 上海昂博生物技术有限公司 | 一种奥曲肽粗品的固相制备方法 |
JP6382488B2 (ja) * | 2013-02-21 | 2018-08-29 | ケミカル アンド バイオファーマシューティカル ラボラトリーズ オブ パトラ エス.エー. | 側鎖結合を介する固相ペプチド合成 |
WO2017175107A1 (fr) * | 2016-04-04 | 2017-10-12 | Emcure Pharmaceuticals Limited | Procédé de préparation d'acétate d'octréotide |
CN117534728A (zh) * | 2024-01-10 | 2024-02-09 | 哈尔滨吉象隆生物技术有限公司 | 一种奥曲肽三硫键杂质e的制备方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2144357B1 (es) * | 1998-01-29 | 2000-12-16 | Lipotec Sa | Procedimiento para la obtencion del analogo de somatostatina octreotide. |
US6476186B1 (en) * | 2000-05-23 | 2002-11-05 | Institute Of Nuclear Energy Research | Process for preparing octreotide and derivatives thereof |
AU2003245030A1 (en) * | 2002-05-22 | 2003-12-02 | Suresh Beri | Novel process for production of the somatostatin analog, octreotide |
-
2004
- 2004-03-12 CA CA002458084A patent/CA2458084A1/fr not_active Abandoned
-
2005
- 2005-03-14 WO PCT/CA2005/000378 patent/WO2005087794A1/fr active Application Filing
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013132505A1 (fr) | 2012-03-09 | 2013-09-12 | Natco Pharma Limited | Procédé amélioré pour la préparation d'octréotide par une synthèse peptidique en phase solution |
US10087221B2 (en) | 2013-03-21 | 2018-10-02 | Sanofi-Aventis Deutschland Gmbh | Synthesis of hydantoin containing peptide products |
US10450343B2 (en) | 2013-03-21 | 2019-10-22 | Sanofi-Aventis Deutschland Gmbh | Synthesis of cyclic imide containing peptide products |
Also Published As
Publication number | Publication date |
---|---|
WO2005087794A1 (fr) | 2005-09-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FZDE | Discontinued |