CA2452055C - Integrated automatic blood collection and processing unit - Google Patents

Integrated automatic blood collection and processing unit Download PDF

Info

Publication number
CA2452055C
CA2452055C CA002452055A CA2452055A CA2452055C CA 2452055 C CA2452055 C CA 2452055C CA 002452055 A CA002452055 A CA 002452055A CA 2452055 A CA2452055 A CA 2452055A CA 2452055 C CA2452055 C CA 2452055C
Authority
CA
Canada
Prior art keywords
separation channel
flow
plasma
red blood
centrifuge
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002452055A
Other languages
English (en)
French (fr)
Other versions
CA2452055A1 (en
Inventor
Thomas Charles Robinson
Thomas P. Robinson
Thomas P. Sahines
Richard D'elia
Paul Eibe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mission Medical Inc
Original Assignee
Mission Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mission Medical Inc filed Critical Mission Medical Inc
Publication of CA2452055A1 publication Critical patent/CA2452055A1/en
Application granted granted Critical
Publication of CA2452055C publication Critical patent/CA2452055C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • A61M1/3696Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02Blood transfusion apparatus
    • A61M1/0209Multiple bag systems for separating or storing blood components
    • A61M1/0218Multiple bag systems for separating or storing blood components with filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36222Details related to the interface between cassette and machine
    • A61M1/362227Details related to the interface between cassette and machine the interface providing means for actuating on functional elements of the cassette, e.g. plungers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36224Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with sensing means or components thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362265Details of valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362266Means for adding solutions or substances to the blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3627Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • A61M1/3633Blood component filters, e.g. leukocyte filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362261Constructional details of cassettes, e.g. specific details on material or shape at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/12General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/33Controlling, regulating or measuring
    • A61M2205/3306Optical measuring means
    • A61M2205/331Optical measuring means used as turbidity change detectors, e.g. for priming-blood or plasma-hemoglubine-interface detection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6063Optical identification systems
    • A61M2205/6072Bar codes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B04CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04BCENTRIFUGES
    • B04B5/00Other centrifuges
    • B04B5/04Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0442Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
    • B04B2005/045Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation having annular separation channels

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Centrifugal Separators (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
CA002452055A 2001-06-25 2002-06-25 Integrated automatic blood collection and processing unit Expired - Fee Related CA2452055C (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US30087301P 2001-06-25 2001-06-25
US60/300,873 2001-06-25
US37414102P 2002-04-19 2002-04-19
US60/374,141 2002-04-19
US10/179,920 2002-06-24
US10/179,920 US6890291B2 (en) 2001-06-25 2002-06-24 Integrated automatic blood collection and processing unit
PCT/US2002/022269 WO2003000026A2 (en) 2001-06-25 2002-06-25 Integrated automatic blood collection and processing unit

Publications (2)

Publication Number Publication Date
CA2452055A1 CA2452055A1 (en) 2003-01-03
CA2452055C true CA2452055C (en) 2007-01-09

Family

ID=27391196

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002452055A Expired - Fee Related CA2452055C (en) 2001-06-25 2002-06-25 Integrated automatic blood collection and processing unit

Country Status (9)

Country Link
US (3) US6890291B2 (enExample)
EP (1) EP1412091B1 (enExample)
JP (1) JP4070716B2 (enExample)
AT (1) ATE340652T1 (enExample)
AU (1) AU2002327241B2 (enExample)
CA (1) CA2452055C (enExample)
DE (1) DE60215014T2 (enExample)
ES (1) ES2271324T3 (enExample)
WO (1) WO2003000026A2 (enExample)

Families Citing this family (174)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524231B1 (en) 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
MXPA02002500A (es) * 2000-07-07 2004-09-10 Baxter Int Sistema medico, metodo y aparato utilizando sensores micro-electromecanicos.
US6989891B2 (en) 2001-11-08 2006-01-24 Optiscan Biomedical Corporation Device and method for in vitro determination of analyte concentrations within body fluids
US7211037B2 (en) 2002-03-04 2007-05-01 Therakos, Inc. Apparatus for the continuous separation of biological fluids into components and method of using same
US7479123B2 (en) 2002-03-04 2009-01-20 Therakos, Inc. Method for collecting a desired blood component and performing a photopheresis treatment
US7297272B2 (en) 2002-10-24 2007-11-20 Fenwal, Inc. Separation apparatus and method
US7271912B2 (en) 2003-04-15 2007-09-18 Optiscan Biomedical Corporation Method of determining analyte concentration in a sample using infrared transmission data
CA2522487A1 (en) * 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Sample element qualification
CA2522485A1 (en) * 2003-04-15 2004-10-28 Optiscan Biomedical Corporation Dual measurement analyte detection system
US8029454B2 (en) 2003-11-05 2011-10-04 Baxter International Inc. High convection home hemodialysis/hemofiltration and sorbent system
US8038639B2 (en) 2004-11-04 2011-10-18 Baxter International Inc. Medical fluid system with flexible sheeting disposable unit
US9604014B2 (en) 2004-05-21 2017-03-28 Clearline Md, Llc System for detecting and removing a gas bubble from a vascular infusion line
JP5129568B2 (ja) * 2004-05-21 2013-01-30 アニシージア・セイフティ・プロダクツ・エルエルシー 脈管注入ラインから気泡を検出し、除去するためのシステム
US7092797B2 (en) * 2004-05-25 2006-08-15 Sherwood Services Ag Flow monitoring system for a flow control apparatus
AU2005299929A1 (en) * 2004-10-21 2006-05-04 Optiscan Biomedical Corporation Method and apparatus for determining an analyte concentration in a sample having interferents
US7476209B2 (en) 2004-12-21 2009-01-13 Therakos, Inc. Method and apparatus for collecting a blood component and performing a photopheresis treatment
US8140140B2 (en) * 2005-02-14 2012-03-20 Optiscan Biomedical Corporation Analyte detection system for multiple analytes
US8936755B2 (en) 2005-03-02 2015-01-20 Optiscan Biomedical Corporation Bodily fluid composition analyzer with disposable cassette
US7785258B2 (en) * 2005-10-06 2010-08-31 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US7364562B2 (en) * 2005-10-06 2008-04-29 Optiscan Biomedical Corp. Anti-clotting apparatus and methods for fluid handling system
US20060189926A1 (en) * 2005-02-14 2006-08-24 Hall W D Apparatus and methods for analyzing body fluid samples
US7860542B2 (en) * 2005-02-14 2010-12-28 Optiscan Biomedical Corporation Analyte detection system with reduced sample volume
US8251907B2 (en) * 2005-02-14 2012-08-28 Optiscan Biomedical Corporation System and method for determining a treatment dose for a patient
US20060235348A1 (en) * 2005-02-14 2006-10-19 Callicoat David N Method of extracting and analyzing the composition of bodily fluids
US7766900B2 (en) * 2005-02-21 2010-08-03 Biomet Manufacturing Corp. Method and apparatus for application of a fluid
US20060226086A1 (en) * 2005-04-08 2006-10-12 Robinson Thomas C Centrifuge for blood processing systems
US20060226087A1 (en) * 2005-04-08 2006-10-12 Mission Medical, Inc. Method and apparatus for blood separations
US7473216B2 (en) * 2005-04-21 2009-01-06 Fresenius Hemocare Deutschland Gmbh Apparatus for separation of a fluid with a separation channel having a mixer component
US7633708B2 (en) * 2005-04-25 2009-12-15 Hitachi Global Storage Technologies Netherlands B.V. Collapsible bypass channel disposed outside of disk drive housing
CN101268466A (zh) * 2005-07-19 2008-09-17 托马斯·C·汉森 切向制造系统
US7846131B2 (en) * 2005-09-30 2010-12-07 Covidien Ag Administration feeding set and flow control apparatus with secure loading features
US9561001B2 (en) 2005-10-06 2017-02-07 Optiscan Biomedical Corporation Fluid handling cassette system for body fluid analyzer
US20070179435A1 (en) * 2005-12-21 2007-08-02 Braig James R Analyte detection system with periodic sample draw and body fluid analyzer
US9108962B2 (en) 2005-12-19 2015-08-18 Sicor, Inc. Forms of tiotropium bromide and processes for preparation thereof
BRPI0608427A2 (pt) 2005-12-19 2009-12-29 Sicor Inc novas formas de brometo de tiotrópio e processos para seu preparo
US7722573B2 (en) * 2006-03-02 2010-05-25 Covidien Ag Pumping apparatus with secure loading features
US7927304B2 (en) 2006-03-02 2011-04-19 Tyco Healthcare Group Lp Enteral feeding pump and feeding set therefor
US8021336B2 (en) 2007-01-05 2011-09-20 Tyco Healthcare Group Lp Pump set for administering fluid with secure loading features and manufacture of component therefor
US7763005B2 (en) 2006-03-02 2010-07-27 Covidien Ag Method for using a pump set having secure loading features
US7758551B2 (en) * 2006-03-02 2010-07-20 Covidien Ag Pump set with secure loading features
US7722562B2 (en) 2006-03-02 2010-05-25 Tyco Healthcare Group Lp Pump set with safety interlock
WO2007120746A2 (en) 2006-04-11 2007-10-25 Optiscan Biomedical Corporation Anti-clotting apparatus and methods for fluid handling system
US8348879B2 (en) 2006-08-28 2013-01-08 Novartis Ag Surgical system having a cassette with an acoustic air reflector
WO2008030927A2 (en) * 2006-09-06 2008-03-13 Optiscan Biomedical Corporation Infusion flow interruption method and apparatus
EP1911520A1 (fr) * 2006-10-10 2008-04-16 Jean-Denis Rochat Ensemble jetable pour la séparation de sang ou le lavage de composant du sang
US7560686B2 (en) * 2006-12-11 2009-07-14 Tyco Healthcare Group Lp Pump set and pump with electromagnetic radiation operated interlock
US20080200859A1 (en) * 2007-02-15 2008-08-21 Mehdi Hatamian Apheresis systems & methods
US20090160656A1 (en) * 2007-10-11 2009-06-25 Mahesh Seetharaman Analyte monitoring system alarms
WO2008144575A2 (en) 2007-05-18 2008-11-27 Optiscan Biomedical Corporation Fluid injection and safety system
US8597190B2 (en) 2007-05-18 2013-12-03 Optiscan Biomedical Corporation Monitoring systems and methods with fast initialization
US20090156911A1 (en) * 2007-10-08 2009-06-18 Optiscan Biomedical Corporation Low draw volume analyte detection systems
US8417311B2 (en) * 2008-09-12 2013-04-09 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US8412293B2 (en) * 2007-07-16 2013-04-02 Optiscan Biomedical Corporation Systems and methods for determining physiological parameters using measured analyte values
US7655124B2 (en) * 2007-10-05 2010-02-02 Mady Attila Apparatus to assist platelet manipulation to prevent and treat endovascular disease and its sequelae
EP2695573B1 (en) 2007-10-10 2021-04-28 Optiscan Biomedical Corporation Fluid component analysis system and method for glucose monitoring and control
US8114276B2 (en) 2007-10-24 2012-02-14 Baxter International Inc. Personal hemodialysis system
KR100886914B1 (ko) * 2007-11-01 2009-03-09 주식회사 아이센스 혈액 분석 장치용 카트리지 및 이를 이용한 혈액 분석 장치
WO2009082519A1 (en) * 2007-12-26 2009-07-02 Caridianbct, Inc. Method and apparatus for controlled addition of solutions to blood components
US8075468B2 (en) * 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8685258B2 (en) 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
US8182769B2 (en) * 2008-04-04 2012-05-22 Biomet Biologics, Llc Clean transportation system
US8518272B2 (en) * 2008-04-04 2013-08-27 Biomet Biologics, Llc Sterile blood separating system
US8628489B2 (en) 2008-04-14 2014-01-14 Haemonetics Corporation Three-line apheresis system and method
US7959598B2 (en) 2008-08-20 2011-06-14 Asante Solutions, Inc. Infusion pump systems and methods
US7951059B2 (en) * 2008-09-18 2011-05-31 Caridianbct, Inc. Blood processing apparatus with optical reference control
US8323482B2 (en) * 2008-10-15 2012-12-04 B. Braun Avitum Ag Extracorporeal blood therapy apparatus control unit housing with removable panels and manually operated panel engaging components
FR2941385B1 (fr) 2009-01-23 2011-04-01 Millipore Corp Procede pour fournir un circuit pour liquide biologique et circuit obtenu.
JP5419008B2 (ja) * 2009-04-28 2014-02-19 Smc株式会社 ポンプ装置
DK2427228T3 (da) * 2009-05-06 2013-05-13 Alcon Res Ltd Multisegmenteret peristaltisk pumpe og kassette
US9554742B2 (en) 2009-07-20 2017-01-31 Optiscan Biomedical Corporation Fluid analysis system
WO2011011462A1 (en) 2009-07-20 2011-01-27 Optiscan Biomedical Corporation Adjustable connector and dead space reduction
US10475529B2 (en) 2011-07-19 2019-11-12 Optiscan Biomedical Corporation Method and apparatus for analyte measurements using calibration sets
US20110137231A1 (en) 2009-12-08 2011-06-09 Alcon Research, Ltd. Phacoemulsification Hand Piece With Integrated Aspiration Pump
EP2585165B1 (en) 2010-05-03 2017-06-21 Optiscan Biomedical Corporation Adjustable connector, improved fluid flow and reduced clotting risk
US8154274B2 (en) 2010-05-11 2012-04-10 Tyco Healthcare Group Lp Safety interlock
FR2960796B1 (fr) 2010-06-08 2014-01-24 Millipore Corp Dispositif pour une installation de traitement de liquide biologique
FR2960795B1 (fr) * 2010-06-08 2012-07-27 Millipore Corp Dispositif pour une installation de traitement de liquide biologique
FR2960794B1 (fr) * 2010-06-08 2012-07-27 Millipore Corp Dispositif pour une installation de traitement de liquide biologique
EP2580589B1 (en) 2010-06-09 2016-08-31 Optiscan Biomedical Corporation Measuring analytes in a fluid sample drawn from a patient
JP2013538119A (ja) * 2010-08-09 2013-10-10 チャールズ,マーホ 分離、センサ、及び計量分配制御システムを備える、血液遠心分離器
US8469916B2 (en) * 2011-02-28 2013-06-25 Fenwal, Inc. Systems and methods for single needle continuous plasma processing
ITBO20110224A1 (it) * 2011-04-26 2012-10-27 Bellco Srl Gruppo per il monitoraggio di una cassetta di una macchina da dialisi
WO2012154572A1 (en) * 2011-05-06 2012-11-15 Haemonetics Corporation System and method for automated separation of whole blood
US11386993B2 (en) 2011-05-18 2022-07-12 Fenwal, Inc. Plasma collection with remote programming
DE102011078760A1 (de) * 2011-07-06 2013-01-10 Hemacon Gmbh Verfahren und Vorrichtung zur Gewinnung eines Erythrozytenkonzentrates
EP2729784A4 (en) 2011-07-06 2015-05-13 Optiscan Biomedical Corp Measuring cell for liquid analysis system
CN105688302B (zh) * 2011-09-26 2018-11-23 汾沃有限公司 血液处理系统
FR2993572B1 (fr) 2012-07-23 2016-04-15 Emd Millipore Corp Circuit pour liquide biologique comportant une vanne a pincement
EP3539590B1 (en) 2012-11-05 2025-01-08 Haemonetics Corporation Continuous flow separation chamber
DE102012022826B4 (de) * 2012-11-22 2022-10-13 Hubert Wöllenstein Verfahren zur Herstellung eines gepoolten Thrombozytenkonzentrats
JP6495174B2 (ja) 2012-12-06 2019-04-03 ステムバイオス テクノロジーズ,インコーポレイテッド Lgr5+体性幹細胞
AU2013360295B2 (en) 2012-12-11 2017-07-27 Alcon Inc. Phacoemulsification hand piece with integrated aspiration and irrigation pump
US9109591B2 (en) 2013-03-04 2015-08-18 Bayer Medical Care Inc. Methods and systems for dosing control in an automated fluid delivery system
US9962288B2 (en) 2013-03-07 2018-05-08 Novartis Ag Active acoustic streaming in hand piece for occlusion surge mitigation
US9915274B2 (en) 2013-03-15 2018-03-13 Novartis Ag Acoustic pumps and systems
US9126219B2 (en) 2013-03-15 2015-09-08 Alcon Research, Ltd. Acoustic streaming fluid ejector
US9545337B2 (en) 2013-03-15 2017-01-17 Novartis Ag Acoustic streaming glaucoma drainage device
US9750638B2 (en) 2013-03-15 2017-09-05 Novartis Ag Systems and methods for ocular surgery
US9693896B2 (en) 2013-03-15 2017-07-04 Novartis Ag Systems and methods for ocular surgery
US9714650B2 (en) * 2013-06-11 2017-07-25 Matthew G. Morris, Jr. Pumping system
US9561324B2 (en) 2013-07-19 2017-02-07 Bigfoot Biomedical, Inc. Infusion pump system and method
WO2015095239A1 (en) 2013-12-18 2015-06-25 Optiscan Biomedical Corporation Systems and methods for detecting leaks
GB2523989B (en) 2014-01-30 2020-07-29 Insulet Netherlands B V Therapeutic product delivery system and method of pairing
US10159778B2 (en) 2014-03-24 2018-12-25 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US10376627B2 (en) 2014-03-24 2019-08-13 Fenwal, Inc. Flexible biological fluid filters
US9968738B2 (en) 2014-03-24 2018-05-15 Fenwal, Inc. Biological fluid filters with molded frame and methods for making such filters
US9782707B2 (en) 2014-03-24 2017-10-10 Fenwal, Inc. Biological fluid filters having flexible walls and methods for making such filters
US9796166B2 (en) 2014-03-24 2017-10-24 Fenwal, Inc. Flexible biological fluid filters
US10912875B2 (en) * 2014-10-09 2021-02-09 Fresenius Medical Care Holdings, Inc. Sensing negative pressure with a pressure transducer
WO2016081553A1 (en) * 2014-11-19 2016-05-26 StemBios Technologies, Inc. Somatic stem cells for treating bone defects
CN107405446B (zh) 2015-02-18 2020-09-29 英赛罗公司 流体输送和输注装置及其使用方法
US9827365B2 (en) * 2015-11-02 2017-11-28 Fenwal, Inc. Systems and methods for automated air removal in products comprising biological fluids
HK1257246A1 (zh) 2016-01-13 2019-10-18 Bigfoot Biomedical, Inc. 糖尿病管理系统的用户界面
US10610643B2 (en) 2016-01-14 2020-04-07 Bigfoot Biomedical, Inc. Occlusion resolution in medication delivery devices, systems, and methods
HK1257093A1 (zh) 2016-01-14 2019-10-11 Bigfoot Biomedical, Inc. 调整胰岛素输送速率
WO2017181077A1 (en) * 2016-04-14 2017-10-19 Terumo Bct, Inc. Loading of disposable
EP3445417A4 (en) * 2016-04-22 2019-11-20 Stembios Technologies, Inc. BLOOD SEPARATION SYSTEM
US12383166B2 (en) 2016-05-23 2025-08-12 Insulet Corporation Insulin delivery system and methods with risk-based set points
US10765807B2 (en) 2016-09-23 2020-09-08 Insulet Corporation Fluid delivery device with sensor
CA3037432A1 (en) 2016-12-12 2018-06-21 Bigfoot Biomedical, Inc. Alarms and alerts for medication delivery devices and related systems and methods
US10610644B2 (en) 2017-01-13 2020-04-07 Bigfoot Biomedical, Inc. Insulin delivery methods, systems and devices
US10758675B2 (en) 2017-01-13 2020-09-01 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US10881793B2 (en) 2017-01-13 2021-01-05 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
US11027063B2 (en) 2017-01-13 2021-06-08 Bigfoot Biomedical, Inc. Insulin delivery methods, systems and devices
US10500334B2 (en) 2017-01-13 2019-12-10 Bigfoot Biomedical, Inc. System and method for adjusting insulin delivery
SG11201909722WA (en) 2017-04-21 2019-11-28 Terumo Bct Inc Methods and systems for high-throughput blood component collection
US10792416B2 (en) 2017-05-30 2020-10-06 Haemonetics Corporation System and method for collecting plasma
US10758652B2 (en) 2017-05-30 2020-09-01 Haemonetics Corporation System and method for collecting plasma
US10561784B2 (en) 2017-05-31 2020-02-18 Fenwal, Inc. Stationary optical monitoring system for blood processing system
EP3630216A4 (en) * 2017-06-02 2021-06-30 Clearline MD, LLC SYSTEM FOR DETECTION AND ELIMINATION OF A GAS BUBBLE FROM A VASCULAR INFUSION LINE
US11065376B2 (en) 2018-03-26 2021-07-20 Haemonetics Corporation Plasmapheresis centrifuge bowl
USD928199S1 (en) 2018-04-02 2021-08-17 Bigfoot Biomedical, Inc. Medication delivery device with icons
US11565043B2 (en) 2018-05-04 2023-01-31 Insulet Corporation Safety constraints for a control algorithm based drug delivery system
US12033750B2 (en) 2018-05-21 2024-07-09 Fenwal, Inc. Plasma collection
ES2951551T3 (es) 2018-05-21 2023-10-23 Fenwal Inc Sistemas y métodos para la optimización de los volúmenes de recolección de plasma
US11412967B2 (en) 2018-05-21 2022-08-16 Fenwal, Inc. Systems and methods for plasma collection
AU2019347755B2 (en) 2018-09-28 2023-02-02 Insulet Corporation Activity mode for artificial pancreas system
WO2020077223A1 (en) 2018-10-11 2020-04-16 Insulet Corporation Event detection for drug delivery system
USD920343S1 (en) 2019-01-09 2021-05-25 Bigfoot Biomedical, Inc. Display screen or portion thereof with graphical user interface associated with insulin delivery
US12415023B2 (en) 2019-04-09 2025-09-16 Nxstage Medical, Inc. Disposable medical flow-regulating device and system
US11801344B2 (en) 2019-09-13 2023-10-31 Insulet Corporation Blood glucose rate of change modulation of meal and correction insulin bolus quantity
WO2021054238A1 (en) * 2019-09-20 2021-03-25 Terumo Kabushiki Kaisha Biological component cassette, biological component kit, and biological component treatment system
US11935637B2 (en) 2019-09-27 2024-03-19 Insulet Corporation Onboarding and total daily insulin adaptivity
WO2021113647A1 (en) 2019-12-06 2021-06-10 Insulet Corporation Techniques and devices providing adaptivity and personalization in diabetes treatment
CA3165121A1 (en) * 2019-12-17 2021-06-24 Johnson & Johnson Surgical Vision, Inc. Irrigation/aspiration pump head and bladder design and methods
AU2020410412A1 (en) 2019-12-17 2022-08-11 Johnson & Johnson Surgical Vision, Inc. Systems and methods for providing a pulseless peristaltic pump
US11833329B2 (en) 2019-12-20 2023-12-05 Insulet Corporation Techniques for improved automatic drug delivery performance using delivery tendencies from past delivery history and use patterns
US12036389B2 (en) 2020-01-06 2024-07-16 Insulet Corporation Prediction of meal and/or exercise events based on persistent residuals
EP4100958A1 (en) 2020-02-03 2022-12-14 Insulet Corporation Use of fuzzy logic in predicting user behavior affecting blood glucose concentration
US11551802B2 (en) 2020-02-11 2023-01-10 Insulet Corporation Early meal detection and calorie intake detection
US11547800B2 (en) 2020-02-12 2023-01-10 Insulet Corporation User parameter dependent cost function for personalized reduction of hypoglycemia and/or hyperglycemia in a closed loop artificial pancreas system
US11986630B2 (en) 2020-02-12 2024-05-21 Insulet Corporation Dual hormone delivery system for reducing impending hypoglycemia and/or hyperglycemia risk
US11324889B2 (en) 2020-02-14 2022-05-10 Insulet Corporation Compensation for missing readings from a glucose monitor in an automated insulin delivery system
US12495994B2 (en) 2020-02-20 2025-12-16 Insulet Corporation Meal bolus subcategories in model based insulin therapy
US11607493B2 (en) 2020-04-06 2023-03-21 Insulet Corporation Initial total daily insulin setting for user onboarding
EP4185348A1 (en) 2020-07-22 2023-05-31 Insulet Corporation Open-loop insulin delivery basal parameters based on insulin delivery records
US11684716B2 (en) 2020-07-31 2023-06-27 Insulet Corporation Techniques to reduce risk of occlusions in drug delivery systems
EP4221588A1 (en) 2020-09-30 2023-08-09 Insulet Corporation Secure wireless communications between a glucose monitor and other devices
WO2022072332A1 (en) 2020-09-30 2022-04-07 Insulet Corporation Drug delivery device with integrated optical-based glucose monitor
US11160925B1 (en) 2021-01-29 2021-11-02 Insulet Corporation Automatic drug delivery system for delivery of a GLP-1 therapeutic
EP4035700B1 (en) 2021-01-29 2025-03-05 Fenwal, Inc. Automated splitting of a fluid into uneven volumes
US11898967B2 (en) 2021-02-02 2024-02-13 Fenwal, Inc. Predicting malfunction and failure of centrifuge umbilicus
US11904140B2 (en) 2021-03-10 2024-02-20 Insulet Corporation Adaptable asymmetric medicament cost component in a control system for medicament delivery
WO2022192482A1 (en) 2021-03-10 2022-09-15 Insulet Corporation A medicament delivery device with an adjustable and piecewise analyte level cost component to address persistent positive analyte level excursions
EP4070826A3 (en) * 2021-04-05 2022-11-30 Fenwal, Inc. Continuous flow centrifugation chambers
US12496398B2 (en) 2021-05-28 2025-12-16 Insulet Corporation Threshold based automatic glucose control response
EP4101482A1 (en) 2021-06-07 2022-12-14 Insulet Corporation Exercise safety prediction based on physiological conditions
WO2023049900A1 (en) 2021-09-27 2023-03-30 Insulet Corporation Techniques enabling adaptation of parameters in aid systems by user input
US11439754B1 (en) 2021-12-01 2022-09-13 Insulet Corporation Optimizing embedded formulations for drug delivery
EP4238655A1 (en) * 2022-02-28 2023-09-06 Fenwal, Inc. Continuous-flow centrifuge chambers having a non-uniform radius high-g wall
USD1039166S1 (en) * 2022-03-08 2024-08-13 Sarstedt Ag & Co. Kg Device for sorting blood collection tubes
US20240042118A1 (en) * 2022-08-02 2024-02-08 Terumo Bct, Inc. Methods And Systems For High-Throughput Blood Component Collection
CN115901560B (zh) * 2022-10-27 2025-10-03 深圳赛桥生物创新技术有限公司 红细胞浓度变化处理方法、装置、系统及介质
CA3275991A1 (en) 2023-01-06 2024-07-11 Insulet Corporation Automatic or manual administration of meal boluses with subsequent automatic relaxation of safety constraints

Family Cites Families (186)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3655123A (en) * 1966-08-08 1972-04-11 Us Health Education & Welfare Continuous flow blood separator
US3864089A (en) 1973-12-10 1975-02-04 Atomic Energy Commission Multiple-sample rotor assembly for blood fraction preparation
US3951148A (en) 1974-05-29 1976-04-20 Pharmachem Corporation Blood component storage bag and glycerolizing set therefor
US4056224A (en) 1975-03-27 1977-11-01 Baxter Travenol Laboratories, Inc. Flow system for centrifugal liquid processing apparatus
US3957197A (en) * 1975-04-25 1976-05-18 The United States Of America As Represented By The United States Energy Research And Development Administration Centrifuge apparatus
US4010894A (en) * 1975-11-21 1977-03-08 International Business Machines Corporation Centrifuge fluid container
US4007871A (en) * 1975-11-13 1977-02-15 International Business Machines Corporation Centrifuge fluid container
US4636193A (en) * 1976-05-14 1987-01-13 Baxter Travenol Laboratories, Inc. Disposable centrifugal blood processing system
US4734089A (en) * 1976-05-14 1988-03-29 Baxter Travenol Laboratories, Inc. Centrifugal blood processing system
US4086924A (en) * 1976-10-06 1978-05-02 Haemonetics Corporation Plasmapheresis apparatus
US4091989A (en) * 1977-01-04 1978-05-30 Schlutz Charles A Continuous flow fractionation and separation device and method
US4419089A (en) 1977-07-19 1983-12-06 The United States Of America As Represented By The Department Of Health And Human Services Blood cell separator
US4356958A (en) 1977-07-19 1982-11-02 The United States Of America As Represented By The Secretary Of Health And Human Services Blood cell separator
US5217426A (en) * 1977-08-12 1993-06-08 Baxter International Inc. Combination disposable plastic blood receiving container and blood component centrifuge
US5571068A (en) 1977-08-12 1996-11-05 Baxter International Inc. Centrifuge assembly
US5217427A (en) * 1977-08-12 1993-06-08 Baxter International Inc. Centrifuge assembly
US4114802A (en) 1977-08-29 1978-09-19 Baxter Travenol Laboratories, Inc. Centrifugal apparatus with biaxial connector
US4387848A (en) * 1977-10-03 1983-06-14 International Business Machines Corporation Centrifuge assembly
US4379452A (en) * 1977-10-18 1983-04-12 Baxter Travenol Laboratories, Inc. Prepackaged, self-contained fluid circuit module
US4386730A (en) * 1978-07-21 1983-06-07 International Business Machines Corporation Centrifuge assembly
US4285464A (en) 1979-01-22 1981-08-25 Haemonetics Corporation Apparatus for separation of blood into components thereof
US4303193A (en) 1979-01-22 1981-12-01 Haemonetics Corporation Apparatus for separating blood into components thereof
SE7908036L (sv) 1979-09-28 1981-03-29 Gambro Dialysatoren Separationsenhet for separering av vetskor, speciellt helblod
US4344560A (en) 1979-11-02 1982-08-17 Asahi Kasei Kogyo Kabushiki Kaisha Container, apparatus and method for separating platelets
DE2948177A1 (de) * 1979-11-30 1981-06-04 Dr. Eduard Fresenius Chemisch-Pharmazeutische Industrie Kg Apparatebau Kg, 6380 Bad Homburg Separator fuer eine ultrazentrifuge
US4637813A (en) * 1979-12-06 1987-01-20 Baxter Travenol Laboratories, Inc. Blood processing assembly including a prepackaged fluid circuit module
JPS56144759A (en) * 1980-04-11 1981-11-11 Tetsuo Matsumoto Apparatus for separating and mixing liquid component, and apparatus for separating, mixing and discharging the same
US4304357A (en) 1980-06-16 1981-12-08 Haemonetics Corporation Blood processing centrifuge
US4416654A (en) 1981-09-03 1983-11-22 Haemonetics Corporation Pheresis apparatus
US4464167A (en) 1981-09-03 1984-08-07 Haemonetics Corporation Pheresis apparatus
US4531932A (en) 1981-11-27 1985-07-30 Dideco S.P.A. Centrifugal plasmapheresis device
US4447221A (en) * 1982-06-15 1984-05-08 International Business Machines Corporation Continuous flow centrifuge assembly
US4680025A (en) 1982-08-24 1987-07-14 Baxter Travenol Laboratories, Inc. Blood component collection systems and methods
US5034135A (en) 1982-12-13 1991-07-23 William F. McLaughlin Blood fractionation system and method
US4439178A (en) * 1982-12-30 1984-03-27 International Business Machines Corporation Sealless centrifuge processing channel and tube system
DE3570188D1 (en) * 1984-02-24 1989-06-22 Kuraray Co Apparatus for the treatment of plasma
JPS61245855A (ja) 1985-04-22 1986-11-01 Green Cross Corp:The 連続式血液分離装置
GB8521867D0 (en) 1985-09-03 1985-10-09 Fisons Plc Centrifuge
US4647279A (en) * 1985-10-18 1987-03-03 Cobe Laboratories, Inc. Centrifugal separator
US4670002A (en) * 1985-12-09 1987-06-02 Hitachi Koki Company, Ltd. Centrifugal elutriator rotor
US4708712A (en) 1986-03-28 1987-11-24 Cobe Laboratories, Inc. Continuous-loop centrifugal separator
SE8601891D0 (sv) 1986-04-24 1986-04-24 Svante Jonsson Maskin for plasmabytesbehandling och trombocytgivning
US4668214A (en) * 1986-06-09 1987-05-26 Electromedics, Inc. Method of washing red blood cells
US4696666A (en) 1986-07-18 1987-09-29 Rice Jr Richard D Centrifuge machine and rotor
DE3632500A1 (de) 1986-09-24 1988-04-07 Fresenius Ag Zentrifugenanordnung
US5053127A (en) 1987-01-13 1991-10-01 William F. McLaughlin Continuous centrifugation system and method for directly deriving intermediate density material from a suspension
US5792372A (en) 1987-01-30 1998-08-11 Baxter International, Inc. Enhanced yield collection systems and methods for obtaining concentrated platelets from platelet-rich plasma
US5573678A (en) 1987-01-30 1996-11-12 Baxter International Inc. Blood processing systems and methods for collecting mono nuclear cells
US5656163A (en) * 1987-01-30 1997-08-12 Baxter International Inc. Chamber for use in a rotating field to separate blood components
US5632893A (en) * 1987-01-30 1997-05-27 Baxter Internatinoal Inc. Enhanced yield blood processing systems with angled interface control surface
US5076911A (en) 1987-01-30 1991-12-31 Baxter International Inc. Centrifugation chamber having an interface detection surface
US5628915A (en) * 1987-01-30 1997-05-13 Baxter International Inc. Enhanced yield blood processing systems and methods establishing controlled vortex flow conditions
US4834890A (en) * 1987-01-30 1989-05-30 Baxter International Inc. Centrifugation pheresis system
US4806252A (en) * 1987-01-30 1989-02-21 Baxter International Inc. Plasma collection set and method
US5641414A (en) * 1987-01-30 1997-06-24 Baxter International Inc. Blood processing systems and methods which restrict in flow of whole blood to increase platelet yields
US5104526A (en) * 1987-01-30 1992-04-14 Baxter International Inc. Centrifugation system having an interface detection system
US4940543A (en) 1987-01-30 1990-07-10 Baxter International Inc. Plasma collection set
SE458342B (sv) 1987-07-06 1989-03-20 Alfa Laval Ab Centrifugalseparator innefattande en rotor med en separeringskammare bestaaende av tvaa avdelningar
US4850995A (en) 1987-08-19 1989-07-25 Cobe Laboratories, Inc. Centrifugal separation of blood
EP0349188B1 (en) * 1988-06-23 1992-09-02 ASAHI MEDICAL Co., Ltd. Method for separating blood into blood components, and blood components separator unit
US4897185A (en) * 1988-10-06 1990-01-30 Cobe Laboratories, Inc. Cell processing apparatus and method
US5152905A (en) 1989-09-12 1992-10-06 Pall Corporation Method for processing blood for human transfusion
US5242384A (en) 1989-11-13 1993-09-07 Davol, Inc. Blood pumping and processing system
US5186844A (en) * 1991-04-01 1993-02-16 Abaxis, Inc. Apparatus and method for continuous centrifugal blood cell separation
US5141486B1 (en) 1990-11-05 1996-01-30 Cobe Lab Washing cells
US5273517A (en) * 1991-07-09 1993-12-28 Haemonetics Corporation Blood processing method and apparatus with disposable cassette
IT1251147B (it) * 1991-08-05 1995-05-04 Ivo Panzani Tubo multilume per separatore centrifugo particolarmente per sangue
DE4126341C1 (enExample) * 1991-08-09 1993-01-28 Fresenius Ag, 6380 Bad Homburg, De
US5217618A (en) * 1991-08-26 1993-06-08 Terumo Kabushiki Kaisha Plasma purification treatment
DE4129639C1 (enExample) * 1991-09-06 1993-02-11 Fresenius Ag, 6380 Bad Homburg, De
DE4129516C2 (de) * 1991-09-06 2000-03-09 Fresenius Ag Verfahren und Vorrichtung zum Trennen von Blut in seine Bestandteile
US5804079A (en) 1991-12-23 1998-09-08 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US5730883A (en) * 1991-12-23 1998-03-24 Baxter International Inc. Blood processing systems and methods using apparent hematocrit as a process control parameter
AU663160B2 (en) 1991-12-23 1995-09-28 Baxter International Inc. Centrifuge
US5549834A (en) 1991-12-23 1996-08-27 Baxter International Inc. Systems and methods for reducing the number of leukocytes in cellular products like platelets harvested for therapeutic purposes
US5686238A (en) 1992-02-10 1997-11-11 Baxter International Inc. Method and device for testing blood units for viral contamination
US5785869A (en) 1992-02-10 1998-07-28 Baxter International Inc. Method for creating a leukocyte rich sample from a mixed population of blood cells
US5298016A (en) * 1992-03-02 1994-03-29 Advanced Haemotechnologies Apparatus for separating plasma and other wastes from blood
US5496265A (en) * 1992-03-04 1996-03-05 Cobe Laboratories, Inc. Blood component collection system with optimizer
US5437624A (en) 1993-08-23 1995-08-01 Cobe Laboratories, Inc. Single needle recirculation system for harvesting blood components
US5817042A (en) 1992-03-04 1998-10-06 Cobe Laboratories, Inc. Method and apparatus for controlling concentrations in vivos and in tubing systems
US5658240A (en) 1992-03-04 1997-08-19 Cobe Laboratories, Inc. Blood component collection system with optimizer
US5403272A (en) 1992-05-29 1995-04-04 Baxter International Inc. Apparatus and methods for generating leukocyte free platelet concentrate
AU675233B2 (en) 1992-06-10 1997-01-30 Haemonetics Corporation System for treating transition zone material
DE4226974C2 (de) 1992-08-14 1994-08-11 Fresenius Ag Verfahren und Vorrichtung zur kontinuierlichen Aufbereitung einer Zellsuspension
DE4227695C1 (de) * 1992-08-21 1993-10-07 Fresenius Ag Zentrifuge zum Auftrennen von Blut in seine Bestandteile
WO1994008691A1 (en) 1992-10-22 1994-04-28 Baxter International Inc. Enhanced yield blood processing systems and methods establishing vortex flow conditions
DE69328738T2 (de) * 1992-12-01 2000-12-07 Haemonetics Corp., Braintree Vorrichtung zur apherese von roten blutkörperchen
US5614106A (en) * 1993-03-12 1997-03-25 Baxter International Inc. Method and apparatus for collection of platelets
EP0696211B1 (en) * 1993-04-27 2000-09-20 Haemonetics Corporation Apheresis apparatus
US5527472A (en) * 1993-06-14 1996-06-18 Baxter International Inc. Closed systems and methods for removing undesired matter from blood cells
US5427695A (en) * 1993-07-26 1995-06-27 Baxter International Inc. Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate
US5394732A (en) * 1993-09-10 1995-03-07 Cobe Laboratories, Inc. Method and apparatus for ultrasonic detection of air bubbles
JPH0780041A (ja) * 1993-09-20 1995-03-28 Terumo Corp 細胞保存バッグシステム
US5460493A (en) * 1993-11-17 1995-10-24 Baxter International Inc. Organizer frame for holding an array of flexible tubing in alignment with one or more peristaltic pump rotors
ZA948564B (en) * 1993-11-19 1995-07-26 Bristol Myers Squibb Co Liquid separation apparatus and method
DE69426561T2 (de) 1993-12-22 2001-08-23 Baxter International Inc., Deerfield Zentrifuge mit geneigter drehachse und geneigtem bedienungsfeld
US5746708A (en) * 1993-12-22 1998-05-05 Baxter International Inc. Peristaltic pump tube holder with pump tube shield and cover
US5445506A (en) 1993-12-22 1995-08-29 Baxter International Inc. Self loading peristaltic pump tube cassette
US5462416A (en) 1993-12-22 1995-10-31 Baxter International Inc. Peristaltic pump tube cassette for blood processing systems
US5514069A (en) 1993-12-22 1996-05-07 Baxter International Inc. Stress-bearing umbilicus for a compact centrifuge
US5482440A (en) * 1993-12-22 1996-01-09 Baxter Int Blood processing systems using a peristaltic pump module with valve and sensing station for operating a peristaltic pump tube cassette
US5437598A (en) 1994-01-21 1995-08-01 Cobe Laboratories, Inc. Automation of plasma sequestration
US5545339A (en) * 1994-02-25 1996-08-13 Pall Corporation Method for processing biological fluid and treating separated component
US5478479A (en) 1994-05-20 1995-12-26 Haemonetics Corporation Two-stage cell wash process controlled by optical sensor
US5733253A (en) 1994-10-13 1998-03-31 Transfusion Technologies Corporation Fluid separation system
US5651766A (en) * 1995-06-07 1997-07-29 Transfusion Technologies Corporation Blood collection and separation system
US5584320A (en) * 1994-10-31 1996-12-17 Cobe Laboratories, Inc. Multi-tube clamp actuator and mating cartridge
US5581687A (en) 1994-11-10 1996-12-03 Baxter International Inc. Interactive control systems for medical processing devices
EP0793414A2 (en) * 1994-11-14 1997-09-10 Pall Corporation Long-term blood component storage system and method
US5704889A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Spillover collection of sparse components such as mononuclear cells in a centrifuge apparatus
US5704888A (en) * 1995-04-14 1998-01-06 Cobe Laboratories, Inc. Intermittent collection of mononuclear cells in a centrifuge apparatus
US6053856A (en) * 1995-04-18 2000-04-25 Cobe Laboratories Tubing set apparatus and method for separation of fluid components
US6022306A (en) * 1995-04-18 2000-02-08 Cobe Laboratories, Inc. Method and apparatus for collecting hyperconcentrated platelets
US5913768A (en) * 1995-04-18 1999-06-22 Cobe Laboratories, Inc. Particle filter apparatus
US5837150A (en) 1995-06-07 1998-11-17 Cobe Laboratories, Inc. Extracorporeal blood processing methods
US5738644A (en) * 1995-06-07 1998-04-14 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US6790195B2 (en) * 1995-06-07 2004-09-14 Gambro Inc Extracorporeal blood processing methods and apparatus
US5961842A (en) 1995-06-07 1999-10-05 Baxter International Inc. Systems and methods for collecting mononuclear cells employing control of packed red blood cell hematocrit
US5750025A (en) * 1995-06-07 1998-05-12 Cobe Laboratories, Inc. Disposable for an apheresis system with a contoured support
US5704887A (en) 1995-06-07 1998-01-06 Baxter International Inc. Easy load umbilicus holder for a centrifuge
US5676644A (en) 1995-06-07 1997-10-14 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5720716A (en) * 1995-06-07 1998-02-24 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5702357A (en) 1995-06-07 1997-12-30 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
WO1996040322A2 (en) 1995-06-07 1996-12-19 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5653887A (en) 1995-06-07 1997-08-05 Cobe Laboratories, Inc. Apheresis blood processing method using pictorial displays
US5795317A (en) 1995-06-07 1998-08-18 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
US5722946A (en) * 1995-06-07 1998-03-03 Cobe Laboratories, Inc. Extracorporeal blood processing methods and apparatus
JPH0947505A (ja) * 1995-08-08 1997-02-18 Terumo Corp 血液成分分離装置および血小板採取方法
US6251284B1 (en) * 1995-08-09 2001-06-26 Baxter International Inc. Systems and methods which obtain a uniform targeted volume of concentrated red blood cells in diverse donor populations
US5769811A (en) * 1995-10-31 1998-06-23 Haemonetics Corporation Blood-processing machine system
US5964724A (en) 1996-01-31 1999-10-12 Medtronic Electromedics, Inc. Apparatus and method for blood separation
US5637082A (en) * 1996-02-22 1997-06-10 Haemonetics Corporation Adaptive apheresis apparatus
US5865785A (en) * 1996-02-23 1999-02-02 Baxter International Inc. Systems and methods for on line finishing of cellular blood products like platelets harvested for therapeutic purposes
JP3313572B2 (ja) * 1996-04-03 2002-08-12 ヘモネティクス・コーポレーション 血液処理用遠心分離器ボウル
US5792038A (en) 1996-05-15 1998-08-11 Cobe Laboratories, Inc. Centrifugal separation device for providing a substantially coriolis-free pathway
US5904645A (en) * 1996-05-15 1999-05-18 Cobe Laboratories Apparatus for reducing turbulence in fluid flow
US6135940A (en) 1996-09-25 2000-10-24 Becton, Dickinson And Company Centrifugally activated tube rotator mechanism and method for using the same
JP3970331B2 (ja) 1996-11-22 2007-09-05 セラコス・インコーポレイテッド 流体の移動を弁操作、ポンプ処理および制御するための一体型カセット
US5870805A (en) * 1997-01-06 1999-02-16 Baxter International Inc. Disposable tubing set and organizer frame for holding flexible tubing
DE69819689T2 (de) * 1997-02-14 2004-09-23 Dendreon Corp., Seattle Verfahren und gerät zum waschen von zellen
WO1998043720A1 (en) 1997-04-03 1998-10-08 Baxter International Inc. Interface detection and control systems and methods
US5989177A (en) 1997-04-11 1999-11-23 Baxter International Inc. Umbilicus gimbal with bearing retainer
US6344020B1 (en) * 1997-04-11 2002-02-05 Baxter International Inc. Bearing and umbilicus gimbal with bearing retainer in blood processing system
EP0987036B1 (en) 1997-05-20 2006-04-12 Zymequest, Inc. Optical sensors for cell processing systems
US5738060A (en) * 1997-05-29 1998-04-14 Trw Inc. Poppet valve and method of making the poppet valve
US5980760A (en) 1997-07-01 1999-11-09 Baxter International Inc. System and methods for harvesting mononuclear cells by recirculation of packed red blood cells
US6027657A (en) * 1997-07-01 2000-02-22 Baxter International Inc. Systems and methods for collecting diluted mononuclear cells
US6200287B1 (en) * 1997-09-05 2001-03-13 Gambro, Inc. Extracorporeal blood processing methods and apparatus
US6280406B1 (en) 1997-09-12 2001-08-28 Gambro, Inc Extracorporeal blood processing system
US6254784B1 (en) 1997-10-30 2001-07-03 Baxter International Inc. Optical interface detection system for centrifugal blood processing
IT1295939B1 (it) 1997-10-31 1999-05-28 Giammaria Sitar Dispositivo e metodo per la separazione di cellule umane od animali aventi densita' diverse da dispersioni cellulari che le contengono
DE19801767C1 (de) 1998-01-19 1999-10-07 Fresenius Ag Zentrifuge
IT1302015B1 (it) 1998-08-07 2000-07-20 Dideco Spa Sistema di controllo automatico di cella per la centrifugazione delsangue.
DE19836813A1 (de) * 1998-08-14 2000-02-24 Bundesdruckerei Gmbh Wert- und Sicherheitsdokument mit optisch anregbaren Farbstoffen zur Echtheitsprüfung
DE19841835C2 (de) 1998-09-12 2003-05-28 Fresenius Ag Zentrifugenkammer für einen Zellseparator
US6113554A (en) 1998-10-16 2000-09-05 Haemonetics Corporation Automatic whole blood collection system
US6267925B1 (en) 1998-12-07 2001-07-31 Haemonetics Corporation Method for cryopreservation and recovery of red blood cells
US6334842B1 (en) * 1999-03-16 2002-01-01 Gambro, Inc. Centrifugal separation apparatus and method for separating fluid components
EP1057534A1 (en) 1999-06-03 2000-12-06 Haemonetics Corporation Centrifugation bowl with filter core
US6387263B1 (en) * 1999-09-02 2002-05-14 Bristol-Myers Squibb Company Apparatus and methods for preparing plasma solutions from blood with improved separation of plasma
US6294094B1 (en) 1999-09-03 2001-09-25 Baxter International Inc. Systems and methods for sensing red blood cell hematocrit
US6270673B1 (en) 1999-09-03 2001-08-07 Baxter International Inc. Door latching assembly for holding a fluid pressure actuated cassette during use
US6348156B1 (en) * 1999-09-03 2002-02-19 Baxter International Inc. Blood processing systems and methods with sensors to detect contamination due to presence of cellular components or dilution due to presence of plasma
US6322488B1 (en) 1999-09-03 2001-11-27 Baxter International Inc. Blood separation chamber with preformed blood flow passages and centralized connection to external tubing
US6325775B1 (en) 1999-09-03 2001-12-04 Baxter International Inc. Self-contained, transportable blood processsing device
US6709412B2 (en) 1999-09-03 2004-03-23 Baxter International Inc. Blood processing systems and methods that employ an in-line leukofilter mounted in a restraining fixture
US6261065B1 (en) * 1999-09-03 2001-07-17 Baxter International Inc. System and methods for control of pumps employing electrical field sensing
US6875191B2 (en) 1999-09-03 2005-04-05 Baxter International Inc. Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter
US6481980B1 (en) 1999-09-03 2002-11-19 Baxter International Inc. Fluid flow cassette with pressure actuated pump and valve stations
US6315707B1 (en) 1999-09-03 2001-11-13 Baxter International Inc. Systems and methods for seperating blood in a rotating field
US6524231B1 (en) * 1999-09-03 2003-02-25 Baxter International Inc. Blood separation chamber with constricted interior channel and recessed passage
US20020077241A1 (en) 1999-09-03 2002-06-20 Baxter International Inc. Blood processing systems and methods with quick attachment of a blood separation chamber to a centrifuge rotor
US7651474B2 (en) * 1999-10-01 2010-01-26 Caridianbct, Inc. Method and apparatus for leukoreduction of red blood cells
US6730054B2 (en) * 1999-10-16 2004-05-04 Baxter International Inc. Blood collection systems and methods that derive estimated effects upon the donor's blood volume and hematocrit
US6354986B1 (en) * 2000-02-16 2002-03-12 Gambro, Inc. Reverse-flow chamber purging during centrifugal separation
ATE523217T1 (de) * 2000-03-09 2011-09-15 Caridianbct Inc Extrakorporale vorrichtung zur blutverarbeitung
JP2001276663A (ja) 2000-03-30 2001-10-09 Haemonetics Corp 粒子分離用遠心分離ボウル
CN1420796A (zh) 2000-03-31 2003-05-28 巴克斯特国际公司 收集包括不含或实质上不含血细胞的血浆在内的减白细胞的血液组分的系统及方法
US6605223B2 (en) * 2000-06-20 2003-08-12 Medicept, Inc. Blood component preparation (BCP) device and method of use thereof
JP4299452B2 (ja) 2000-11-28 2009-07-22 テルモ株式会社 血小板採取装置
US6808503B2 (en) 2001-03-06 2004-10-26 Baxter International Inc. Automated system and method for pre-surgical blood donation and fluid replacement
US6884228B2 (en) 2001-03-06 2005-04-26 Baxter International Inc. Automated system adaptable for use with different fluid circuits
US6582386B2 (en) 2001-03-06 2003-06-24 Baxter International Inc. Multi-purpose, automated blood and fluid processing systems and methods
DE60230997D1 (de) * 2001-12-05 2009-03-12 Caridianbct Inc Verfahren und vorrichtung zur trennung von blutbestandteilen
US7052606B2 (en) 2001-12-10 2006-05-30 Gambro, Inc. Methods and apparatus for leukoreduction of red blood cells

Also Published As

Publication number Publication date
WO2003000026B1 (en) 2005-01-06
US20030199803A1 (en) 2003-10-23
EP1412091A2 (en) 2004-04-28
ES2271324T3 (es) 2007-04-16
WO2003000026A3 (en) 2003-03-27
US7695423B2 (en) 2010-04-13
DE60215014D1 (de) 2006-11-09
JP2004531321A (ja) 2004-10-14
US7115205B2 (en) 2006-10-03
CA2452055A1 (en) 2003-01-03
DE60215014T2 (de) 2007-05-16
US6890291B2 (en) 2005-05-10
US20070012623A1 (en) 2007-01-18
US20040245189A1 (en) 2004-12-09
JP4070716B2 (ja) 2008-04-02
AU2002327241B2 (en) 2006-03-16
EP1412091B1 (en) 2006-09-27
WO2003000026A2 (en) 2003-01-03
EP1412091A4 (en) 2004-11-17
ATE340652T1 (de) 2006-10-15

Similar Documents

Publication Publication Date Title
CA2452055C (en) Integrated automatic blood collection and processing unit
AU2002327241A1 (en) Integrated automatic blood collection and processing unit
US7037428B1 (en) Integrated automatic blood processing unit
US20060226086A1 (en) Centrifuge for blood processing systems
EP0912250B1 (en) Cell separation system for biological fluids like blood
US6709412B2 (en) Blood processing systems and methods that employ an in-line leukofilter mounted in a restraining fixture
US20060226087A1 (en) Method and apparatus for blood separations
US6875191B2 (en) Blood processing systems and methods that alternate flow of blood component and additive solution through an in-line leukofilter
US20020077582A1 (en) Blood processing systems and methods that assess and respond to real or potential vein occlusion conditions
US20020094927A1 (en) Blood separation systems and methods with umbilicus-driven blood separation chambers
EP1888246A1 (en) Centrifuge for blood processing systems
US20020077241A1 (en) Blood processing systems and methods with quick attachment of a blood separation chamber to a centrifuge rotor

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed