CA2440743A1 - Matrix gene expression in chondrogenesis - Google Patents
Matrix gene expression in chondrogenesis Download PDFInfo
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- CA2440743A1 CA2440743A1 CA002440743A CA2440743A CA2440743A1 CA 2440743 A1 CA2440743 A1 CA 2440743A1 CA 002440743 A CA002440743 A CA 002440743A CA 2440743 A CA2440743 A CA 2440743A CA 2440743 A1 CA2440743 A1 CA 2440743A1
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- 108010069117 seryl-lysyl-aspartic acid Proteins 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
- 102000042290 small heat shock protein (HSP20) family Human genes 0.000 description 1
- 108091052270 small heat shock protein (HSP20) family Proteins 0.000 description 1
- 238000002791 soaking Methods 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- FQENQNTWSFEDLI-UHFFFAOYSA-J sodium diphosphate Chemical compound [Na+].[Na+].[Na+].[Na+].[O-]P([O-])(=O)OP([O-])([O-])=O FQENQNTWSFEDLI-UHFFFAOYSA-J 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 229910000162 sodium phosphate Inorganic materials 0.000 description 1
- 239000012064 sodium phosphate buffer Substances 0.000 description 1
- 229940048086 sodium pyrophosphate Drugs 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 230000000392 somatic effect Effects 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 229940063673 spermidine Drugs 0.000 description 1
- 108010005652 splenotritin Proteins 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000013595 supernatant sample Substances 0.000 description 1
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 238000004114 suspension culture Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 235000019818 tetrasodium diphosphate Nutrition 0.000 description 1
- 239000001577 tetrasodium phosphonato phosphate Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000003161 three-hybrid assay Methods 0.000 description 1
- 208000037816 tissue injury Diseases 0.000 description 1
- 230000020192 tolerance induction in gut-associated lymphoid tissue Effects 0.000 description 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 description 1
- 230000005026 transcription initiation Effects 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 230000037317 transdermal delivery Effects 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 230000008736 traumatic injury Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
- 238000011277 treatment modality Methods 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- HHLJUSLZGFYWKW-UHFFFAOYSA-N triethanolamine hydrochloride Chemical compound Cl.OCCN(CCO)CCO HHLJUSLZGFYWKW-UHFFFAOYSA-N 0.000 description 1
- 239000013638 trimer Substances 0.000 description 1
- PIEPQKCYPFFYMG-UHFFFAOYSA-N tris acetate Chemical compound CC(O)=O.OCC(N)(CO)CO PIEPQKCYPFFYMG-UHFFFAOYSA-N 0.000 description 1
- 239000003656 tris buffered saline Substances 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 239000012137 tryptone Substances 0.000 description 1
- 108010038745 tryptophylglycine Proteins 0.000 description 1
- 108010045269 tryptophyltryptophan Proteins 0.000 description 1
- 230000007306 turnover Effects 0.000 description 1
- 238000003160 two-hybrid assay Methods 0.000 description 1
- 238000010396 two-hybrid screening Methods 0.000 description 1
- 108010020532 tyrosyl-proline Proteins 0.000 description 1
- 241000701447 unidentified baculovirus Species 0.000 description 1
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- 229940088594 vitamin Drugs 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 210000004127 vitreous body Anatomy 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPR3116 | 2001-02-15 | ||
| AUPR3116A AUPR311601A0 (en) | 2001-02-15 | 2001-02-15 | Matrix gene expression in chondrogenesis |
| PCT/AU2002/000163 WO2002064625A1 (en) | 2001-02-15 | 2002-02-15 | Matrix gene expression in chondrogenesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2440743A1 true CA2440743A1 (en) | 2002-08-22 |
Family
ID=3827137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002440743A Abandoned CA2440743A1 (en) | 2001-02-15 | 2002-02-15 | Matrix gene expression in chondrogenesis |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20040157329A1 (https=) |
| EP (1) | EP1370579A4 (https=) |
| JP (1) | JP2004537274A (https=) |
| AU (1) | AUPR311601A0 (https=) |
| CA (1) | CA2440743A1 (https=) |
| NO (1) | NO20033624L (https=) |
| NZ (1) | NZ528202A (https=) |
| WO (1) | WO2002064625A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE602004026944D1 (de) * | 2003-03-28 | 2010-06-10 | Fujifilm Mfg Europe Bv | RGD-angereicherte gelatineähnliche Proteine zur Verhinderung der Blutplättchenaggregation |
| US7318925B2 (en) * | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
| CN1838968A (zh) | 2003-08-08 | 2006-09-27 | 艾伯吉尼斯公司 | 针对甲状旁腺激素(pth)之抗体和其用途 |
| WO2005106495A1 (en) * | 2004-05-04 | 2005-11-10 | Pharmacia & Upjohn Company Llc | Procollagen ii biomarkers and methods |
| US20080082170A1 (en) * | 2006-09-29 | 2008-04-03 | Peterman Marc M | Apparatus and methods for surgical repair |
| ES2678211T3 (es) | 2012-03-27 | 2018-08-09 | Ventana Medical Systems, Inc. | Conjugados de señalización y procedimientos de uso |
| WO2014093836A1 (en) * | 2012-12-13 | 2014-06-19 | University Of Georgia Research Foundation, Inc. | Ossification-inducing composition and methods of use thereof |
| JP2020502056A (ja) * | 2016-11-13 | 2020-01-23 | イマジン ファーマ | 糖尿病、高血圧および高コレステロール血症を治療するための組成物および方法 |
| US20230210942A1 (en) * | 2018-01-09 | 2023-07-06 | Imagine Pharma Llc | Methods and compositions for modulating endothelial cell dysfunction |
| CN113096736B (zh) * | 2021-03-26 | 2023-10-31 | 北京源生康泰基因科技有限公司 | 一种基于纳米孔测序的病毒实时自动分析方法及系统 |
| CN113201487A (zh) * | 2021-07-06 | 2021-08-03 | 广东先康达生物科技有限公司 | 成软骨细胞培养基及成软骨细胞的培养方法 |
| CN113563458B (zh) * | 2021-07-19 | 2023-07-21 | 嘉兴恒杰生物制药股份有限公司 | 一种非变性ii型胶原蛋白的制备方法 |
| JP2024532985A (ja) * | 2021-09-22 | 2024-09-12 | イマジン ファーマ、エルエルシー | 1型糖尿病患者膵臓組織からインスリンおよびグルカゴン分泌細胞を増殖させるための組成物および方法およびその治療的使用 |
| CN119504941B (zh) * | 2024-12-03 | 2026-01-13 | 中国海洋大学 | 一种富含海洋肽钙螯合物的骨健康压片糖果及其制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5080891A (en) * | 1987-08-03 | 1992-01-14 | Ddi Pharmaceuticals, Inc. | Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols |
| US6159464A (en) * | 1990-12-20 | 2000-12-12 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Viral vectors to inhibit leukocyte infiltration or cartilage degradation of joints |
| JP2001512013A (ja) * | 1997-08-01 | 2001-08-21 | ジェンセット | 前立腺に発現される分泌タンパク質の5’est |
| US20030144475A1 (en) * | 1999-12-06 | 2003-07-31 | Seishi Kato | Human protein and cdna |
-
2001
- 2001-02-15 AU AUPR3116A patent/AUPR311601A0/en not_active Abandoned
-
2002
- 2002-02-15 EP EP02700018A patent/EP1370579A4/en not_active Withdrawn
- 2002-02-15 US US10/468,091 patent/US20040157329A1/en not_active Abandoned
- 2002-02-15 CA CA002440743A patent/CA2440743A1/en not_active Abandoned
- 2002-02-15 JP JP2002564954A patent/JP2004537274A/ja active Pending
- 2002-02-15 WO PCT/AU2002/000163 patent/WO2002064625A1/en not_active Ceased
- 2002-02-15 NZ NZ528202A patent/NZ528202A/en unknown
-
2003
- 2003-08-14 NO NO20033624A patent/NO20033624L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AUPR311601A0 (en) | 2001-03-08 |
| EP1370579A4 (en) | 2005-05-11 |
| EP1370579A1 (en) | 2003-12-17 |
| WO2002064625A1 (en) | 2002-08-22 |
| NO20033624L (no) | 2003-10-10 |
| US20040157329A1 (en) | 2004-08-12 |
| NZ528202A (en) | 2005-09-30 |
| JP2004537274A (ja) | 2004-12-16 |
| NO20033624D0 (no) | 2003-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |