CA2438423C - Method and apparatus for detection and measurement of accumulations of magnetic particles - Google Patents
Method and apparatus for detection and measurement of accumulations of magnetic particles Download PDFInfo
- Publication number
- CA2438423C CA2438423C CA002438423A CA2438423A CA2438423C CA 2438423 C CA2438423 C CA 2438423C CA 002438423 A CA002438423 A CA 002438423A CA 2438423 A CA2438423 A CA 2438423A CA 2438423 C CA2438423 C CA 2438423C
- Authority
- CA
- Canada
- Prior art keywords
- magnetic field
- excitation current
- magnetic
- sensing element
- sensor
- Prior art date
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- Expired - Fee Related
Links
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- 239000006249 magnetic particle Substances 0.000 title claims abstract description 28
- 238000005259 measurement Methods 0.000 title claims abstract description 25
- 238000001514 detection method Methods 0.000 title abstract description 33
- 230000035508 accumulation Effects 0.000 title description 10
- 238000009825 accumulation Methods 0.000 title description 10
- 230000005291 magnetic effect Effects 0.000 claims abstract description 72
- 239000002245 particle Substances 0.000 claims abstract description 45
- 239000000758 substrate Substances 0.000 claims abstract description 27
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
- G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
- G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
- G01R33/1215—Measuring magnetisation; Particular magnetometers therefor
Landscapes
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- General Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
- Measuring Magnetic Variables (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/785,403 | 2001-02-16 | ||
| US09/785,403 US6518747B2 (en) | 2001-02-16 | 2001-02-16 | Method and apparatus for quantitative determination of accumulations of magnetic particles |
| PCT/US2002/005116 WO2002067004A1 (en) | 2001-02-16 | 2002-02-12 | Method and apparatus for detection and measurement of accumulations of magnetic particles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2438423A1 CA2438423A1 (en) | 2002-08-29 |
| CA2438423C true CA2438423C (en) | 2009-09-15 |
Family
ID=25135405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002438423A Expired - Fee Related CA2438423C (en) | 2001-02-16 | 2002-02-12 | Method and apparatus for detection and measurement of accumulations of magnetic particles |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6518747B2 (enExample) |
| EP (1) | EP1360515B1 (enExample) |
| JP (1) | JP2004519666A (enExample) |
| CN (1) | CN1300598C (enExample) |
| AT (1) | ATE339696T1 (enExample) |
| CA (1) | CA2438423C (enExample) |
| DE (1) | DE60214674T2 (enExample) |
| WO (1) | WO2002067004A1 (enExample) |
Families Citing this family (129)
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| EP1525447A4 (en) * | 2002-05-31 | 2006-12-06 | Univ California | METHOD AND DEVICE FOR DETECTING INTERESTING SUBSTANCES |
| WO2005111597A1 (ja) * | 2004-05-17 | 2005-11-24 | The Circle For The Promotion Of Science And Engineering | 磁性微粒子の検出装置 |
| US20090224755A1 (en) * | 2004-11-30 | 2009-09-10 | Koninklijke Philips Electronics, N.V. | Means and method for sensing a magnetic stray field in biosensors |
| EP1679524A1 (en) * | 2005-01-11 | 2006-07-12 | Ecole Polytechnique Federale De Lausanne Epfl - Sti - Imm - Lmis3 | Hall sensor and method of operating a Hall sensor |
| US7300631B2 (en) | 2005-05-02 | 2007-11-27 | Bioscale, Inc. | Method and apparatus for detection of analyte using a flexural plate wave device and magnetic particles |
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- 2002-02-12 EP EP02719038A patent/EP1360515B1/en not_active Expired - Lifetime
- 2002-02-12 WO PCT/US2002/005116 patent/WO2002067004A1/en not_active Ceased
- 2002-02-12 CA CA002438423A patent/CA2438423C/en not_active Expired - Fee Related
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| DE60214674D1 (de) | 2006-10-26 |
| CN1300598C (zh) | 2007-02-14 |
| EP1360515B1 (en) | 2006-09-13 |
| WO2002067004A1 (en) | 2002-08-29 |
| US20020135358A1 (en) | 2002-09-26 |
| US6518747B2 (en) | 2003-02-11 |
| HK1058550A1 (en) | 2004-05-21 |
| CA2438423A1 (en) | 2002-08-29 |
| ATE339696T1 (de) | 2006-10-15 |
| EP1360515A1 (en) | 2003-11-12 |
| WO2002067004B1 (en) | 2002-10-24 |
| DE60214674T2 (de) | 2007-09-13 |
| CN1457434A (zh) | 2003-11-19 |
| JP2004519666A (ja) | 2004-07-02 |
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