CA2395652C - Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent Download PDF

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Publication number
CA2395652C
CA2395652C CA002395652A CA2395652A CA2395652C CA 2395652 C CA2395652 C CA 2395652C CA 002395652 A CA002395652 A CA 002395652A CA 2395652 A CA2395652 A CA 2395652A CA 2395652 C CA2395652 C CA 2395652C
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CA
Canada
Prior art keywords
branched
linear
group
formula
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002395652A
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English (en)
French (fr)
Other versions
CA2395652A1 (fr
Inventor
Michel Koch
Francois Tillequin
Sylvie Michel
Elisabeth Seguin
Abdelhakim El Omri
John Hickman
Alain Pierre
Bruno Pfeiffer
Pierre Renard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Les Laboratoires Servier SAS
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Les Laboratoires Servier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by Les Laboratoires Servier SAS filed Critical Les Laboratoires Servier SAS
Publication of CA2395652A1 publication Critical patent/CA2395652A1/fr
Application granted granted Critical
Publication of CA2395652C publication Critical patent/CA2395652C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002395652A 2001-07-25 2002-07-25 Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent Expired - Fee Related CA2395652C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0109910A FR2827864B1 (fr) 2001-07-25 2001-07-25 Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR01.09910 2001-07-25

Publications (2)

Publication Number Publication Date
CA2395652A1 CA2395652A1 (fr) 2003-01-25
CA2395652C true CA2395652C (fr) 2008-12-30

Family

ID=8865868

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002395652A Expired - Fee Related CA2395652C (fr) 2001-07-25 2002-07-25 Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Country Status (24)

Country Link
US (1) US6642248B2 (enExample)
EP (1) EP1297835B1 (enExample)
JP (1) JP2003055381A (enExample)
KR (1) KR100498868B1 (enExample)
CN (1) CN1231484C (enExample)
AR (1) AR036346A1 (enExample)
AT (1) ATE373478T1 (enExample)
AU (1) AU2002300268B2 (enExample)
BR (1) BR0202864A (enExample)
CA (1) CA2395652C (enExample)
DE (1) DE60222515T2 (enExample)
DK (1) DK1297835T3 (enExample)
EA (1) EA005374B1 (enExample)
ES (1) ES2294090T3 (enExample)
FR (1) FR2827864B1 (enExample)
HK (1) HK1053646B (enExample)
HU (1) HUP0202485A3 (enExample)
MX (1) MXPA02006914A (enExample)
NO (1) NO20023556L (enExample)
NZ (1) NZ520377A (enExample)
PL (1) PL355188A1 (enExample)
PT (1) PT1297835E (enExample)
SI (1) SI1297835T1 (enExample)
ZA (1) ZA200205961B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2856687B1 (fr) * 2003-06-25 2005-09-16 Servier Lab Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2865734B1 (fr) * 2004-02-03 2006-05-19 Servier Lab NOUVAEUX DERIVES DE BENZO[b]CHROMENO-NAPHTHYRIDIN-7-ONE ET DE PYRANO[2'3':7,8]QUINO[2,3-b]QUINOXALIN-7-ONE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
FR2879600B1 (fr) * 2004-12-22 2007-02-09 Servier Lab Nouveaux derives cinnamates de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN107068881B (zh) * 2016-04-25 2019-12-03 中节能万润股份有限公司 一种含有吖啶酮类化合物的有机电致发光器件及其应用
CN115594592B (zh) * 2021-06-28 2024-03-19 江西天宇化工有限公司 一种2-氯-3-硝基苯甲酸的制备方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9224169D0 (en) * 1992-11-18 1993-01-06 Lilly Industries Ltd Pharmaceutical compounds
HRP960352A2 (en) * 1996-07-26 1998-08-31 Pliva Pharm & Chem Works Novel coumarin quinoline carboxylic acids
FR2772765B1 (fr) * 1997-12-19 2000-03-17 Adir Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2795071B1 (fr) * 1999-06-16 2001-07-27 Adir Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HUP0202485A2 (hu) 2003-04-28
NZ520377A (en) 2004-03-26
NO20023556D0 (no) 2002-07-25
FR2827864A1 (fr) 2003-01-31
KR100498868B1 (ko) 2005-07-04
KR20030010513A (ko) 2003-02-05
US6642248B2 (en) 2003-11-04
AR036346A1 (es) 2004-09-01
DE60222515D1 (de) 2007-10-31
CN1231484C (zh) 2005-12-14
JP2003055381A (ja) 2003-02-26
ZA200205961B (en) 2003-04-01
EA200200712A1 (ru) 2003-02-27
PL355188A1 (en) 2003-01-27
HU0202485D0 (enExample) 2002-09-28
DK1297835T3 (da) 2008-01-28
HUP0202485A3 (en) 2005-07-28
ES2294090T3 (es) 2008-04-01
US20030073841A1 (en) 2003-04-17
ATE373478T1 (de) 2007-10-15
CN1398863A (zh) 2003-02-26
PT1297835E (pt) 2007-10-19
CA2395652A1 (fr) 2003-01-25
EP1297835A1 (fr) 2003-04-02
FR2827864B1 (fr) 2005-09-16
DE60222515T2 (de) 2008-07-03
SI1297835T1 (sl) 2007-12-31
MXPA02006914A (es) 2005-07-25
BR0202864A (pt) 2003-06-03
EA005374B1 (ru) 2005-02-24
EP1297835B1 (fr) 2007-09-19
HK1053646B (zh) 2006-04-21
NO20023556L (no) 2003-01-27
AU2002300268B2 (en) 2008-05-22
HK1053646A1 (en) 2003-10-31

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Effective date: 20140725