BR0202864A - Compostos de benzo[b]pirano[3,2-h]acridin-7-ona, um processo para sua preparação e composições farmacêuticas contendo os mesmos - Google Patents
Compostos de benzo[b]pirano[3,2-h]acridin-7-ona, um processo para sua preparação e composições farmacêuticas contendo os mesmosInfo
- Publication number
- BR0202864A BR0202864A BR0202864-6A BR0202864A BR0202864A BR 0202864 A BR0202864 A BR 0202864A BR 0202864 A BR0202864 A BR 0202864A BR 0202864 A BR0202864 A BR 0202864A
- Authority
- BR
- Brazil
- Prior art keywords
- nra
- nrarb
- ora
- compounds
- acridin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
"COMPOSTOS DE BENZO[b]PIRANO[3,2-h]ACRIDIN-7-ONA, UM PROCESSO PARA SUA PREPARAçãO E COMPOSIçõES FARMACêUTICAS CONTENDO OS MESMOS". Compostos da fórmula (I): em que: . X e Y representam um grupo selecionado de hidrogênio, halogênio, mercapto, ciano, nitro, alquila, trialoalquila e trialoalquilcarbonilamino, -ORa, -NRaRb, -NRa-C(O)-T~ 1~, -O-C(O)-T~ 1~, -O-T~ 2~-NRaRb, -O-T~ 2~-ORa, -NRa -T~ 2~-NRaRb, -NRa-T~ 2~-ORa e -NRa-T~ 2~-CO~ 2~Ra em que Ra, Rb, T~ 1~, T~ 2~ são como definidos na descrição, ou X e Y juntos formam um grupo metilenodióxi ou etilenodióxi, . R~ 1~ representa um átomo de hidrogênio ou um grupo alquila, . R~ 2~ representa um grupo selecionado de hidrogênio, -ORa, NRaRb, -NRa-C(O)-T~ 1~, -O-C(O)-T~ 1~, -O-T~ 2~-NRaRb, -O-T~ 2~-ORa, -NRa-T~ 2~NRaRb, -NRa-T~ 2~-ORa e -NRa-T~ 2~-CO~ 2~Ra, em que Ra, Rb, T~ 1~ e T~ 2~ são como anteriormente definidos, . R~ 3~ e R~ 4~ representam um átomo de hidrogênio ou um grupo alquila, . W representa um grupo da fórmula -CH(R~ 5~)-CH(R~ 6~)-, -CH=C(R~ 7~)-, -C(R~ 7~)=CH- ou -C(O)-CH(R~ 8~)- em que R~ 5~, R~ 6~, R~ 7~ e R~ 8~ são como definidos na descrição, seus isómeros e N-óxidos, e seus sais de adição com um ácido ou base farmaceuticamente aceitável. Medicamentos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0109910A FR2827864B1 (fr) | 2001-07-25 | 2001-07-25 | Nouveaux derives de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR0202864A true BR0202864A (pt) | 2003-06-03 |
Family
ID=8865868
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR0202864-6A BR0202864A (pt) | 2001-07-25 | 2002-07-24 | Compostos de benzo[b]pirano[3,2-h]acridin-7-ona, um processo para sua preparação e composições farmacêuticas contendo os mesmos |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6642248B2 (pt) |
| EP (1) | EP1297835B1 (pt) |
| JP (1) | JP2003055381A (pt) |
| KR (1) | KR100498868B1 (pt) |
| CN (1) | CN1231484C (pt) |
| AR (1) | AR036346A1 (pt) |
| AT (1) | ATE373478T1 (pt) |
| AU (1) | AU2002300268B2 (pt) |
| BR (1) | BR0202864A (pt) |
| CA (1) | CA2395652C (pt) |
| DE (1) | DE60222515T2 (pt) |
| DK (1) | DK1297835T3 (pt) |
| EA (1) | EA005374B1 (pt) |
| ES (1) | ES2294090T3 (pt) |
| FR (1) | FR2827864B1 (pt) |
| HK (1) | HK1053646B (pt) |
| HU (1) | HUP0202485A3 (pt) |
| MX (1) | MXPA02006914A (pt) |
| NO (1) | NO20023556L (pt) |
| NZ (1) | NZ520377A (pt) |
| PL (1) | PL355188A1 (pt) |
| PT (1) | PT1297835E (pt) |
| SI (1) | SI1297835T1 (pt) |
| ZA (1) | ZA200205961B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2856687B1 (fr) * | 2003-06-25 | 2005-09-16 | Servier Lab | Nouveaux derives de benzo[a]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2865734B1 (fr) * | 2004-02-03 | 2006-05-19 | Servier Lab | NOUVAEUX DERIVES DE BENZO[b]CHROMENO-NAPHTHYRIDIN-7-ONE ET DE PYRANO[2'3':7,8]QUINO[2,3-b]QUINOXALIN-7-ONE, LEUR PROCEDE DE PREPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT |
| FR2879600B1 (fr) * | 2004-12-22 | 2007-02-09 | Servier Lab | Nouveaux derives cinnamates de benzo[b]pyrano[3,2-h]acridin-7-one, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CN107068881B (zh) * | 2016-04-25 | 2019-12-03 | 中节能万润股份有限公司 | 一种含有吖啶酮类化合物的有机电致发光器件及其应用 |
| CN115594592B (zh) * | 2021-06-28 | 2024-03-19 | 江西天宇化工有限公司 | 一种2-氯-3-硝基苯甲酸的制备方法及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9224169D0 (en) * | 1992-11-18 | 1993-01-06 | Lilly Industries Ltd | Pharmaceutical compounds |
| HRP960352A2 (en) * | 1996-07-26 | 1998-08-31 | Pliva Pharm & Chem Works | Novel coumarin quinoline carboxylic acids |
| FR2772765B1 (fr) * | 1997-12-19 | 2000-03-17 | Adir | Nouveaux derives de l'acronycine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2795071B1 (fr) * | 1999-06-16 | 2001-07-27 | Adir | Nouveaux derives de carboxylate de 7-oxo-2,3,7,14- tetrahydro-1h-benzo[b]pyrano[3,2,h] acridine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2001
- 2001-07-25 FR FR0109910A patent/FR2827864B1/fr not_active Expired - Fee Related
-
2002
- 2002-07-15 MX MXPA02006914A patent/MXPA02006914A/es not_active Application Discontinuation
- 2002-07-24 ES ES02291862T patent/ES2294090T3/es not_active Expired - Lifetime
- 2002-07-24 PL PL02355188A patent/PL355188A1/xx not_active Application Discontinuation
- 2002-07-24 NZ NZ520377A patent/NZ520377A/en unknown
- 2002-07-24 AR ARP020102789A patent/AR036346A1/es unknown
- 2002-07-24 PT PT02291862T patent/PT1297835E/pt unknown
- 2002-07-24 BR BR0202864-6A patent/BR0202864A/pt not_active IP Right Cessation
- 2002-07-24 SI SI200230625T patent/SI1297835T1/sl unknown
- 2002-07-24 EP EP02291862A patent/EP1297835B1/fr not_active Expired - Lifetime
- 2002-07-24 JP JP2002214905A patent/JP2003055381A/ja active Pending
- 2002-07-24 KR KR10-2002-0043537A patent/KR100498868B1/ko not_active IP Right Cessation
- 2002-07-24 DK DK02291862T patent/DK1297835T3/da active
- 2002-07-24 EA EA200200712A patent/EA005374B1/ru not_active IP Right Cessation
- 2002-07-24 CN CNB021253153A patent/CN1231484C/zh not_active Expired - Fee Related
- 2002-07-24 DE DE60222515T patent/DE60222515T2/de not_active Expired - Lifetime
- 2002-07-24 AT AT02291862T patent/ATE373478T1/de not_active IP Right Cessation
- 2002-07-25 ZA ZA200205961A patent/ZA200205961B/xx unknown
- 2002-07-25 HU HU0202485A patent/HUP0202485A3/hu unknown
- 2002-07-25 US US10/205,566 patent/US6642248B2/en not_active Expired - Fee Related
- 2002-07-25 AU AU2002300268A patent/AU2002300268B2/en not_active Ceased
- 2002-07-25 NO NO20023556A patent/NO20023556L/no not_active Application Discontinuation
- 2002-07-25 CA CA002395652A patent/CA2395652C/fr not_active Expired - Fee Related
-
2003
- 2003-07-08 HK HK03104843.8A patent/HK1053646B/zh not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| BR0312513A (pt) | Derivados de glicosìdeo de tiofeno, processos para a produção dos mesmos, medicamentos que contêm esses compostos e uso dos mesmos | |
| ES2158778B1 (es) | Compuestos de sales de paroxetina, su preparacion y uso, y composiciones farmaceuticas que los contienen. | |
| BR0016543A (pt) | Novos derivados de piperidina e piperazina | |
| DE69021755D1 (de) | Benzopyranderivate und Verfahren zu ihrer Herstellung. | |
| EE200300417A (et) | Asendatud aminometüülrühma sisaldavad N-(arüülsulfonüül)beetaaminohappe derivaadid, nende valmistamismeetod ja neid sisaldavad farmatseutilised kompositsioonid | |
| BR0315296A (pt) | Derivados do ciclohexanol espirocìclicos | |
| BR0212069A (pt) | Agentes antidiabéticos orais | |
| ES2159922T3 (es) | Nuevos derivados de bencimidazol, de benzoxazol y de benzotiazol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen. | |
| BR9916669A (pt) | Uso de derivados de ácidos 4-biarilbutìricos e 5-biarilpentanóicos substituìdos como inibidores de metaloproteases de matriz para o tratamento de doenças respiratórias | |
| BR0202864A (pt) | Compostos de benzo[b]pirano[3,2-h]acridin-7-ona, um processo para sua preparação e composições farmacêuticas contendo os mesmos | |
| BR9813217A (pt) | Tetraciclos, processo para a produção dos mesmos e preparações farmacêuticas contendo estes compostos | |
| BR0214937A (pt) | Processo de preparação de derivados de equinocandina | |
| BR9705456A (pt) | Compostos heterocìclicos, processo de aminometila para sua preparação e composições farmacêuticas que os contêm. | |
| BR0106248A (pt) | Inibidores de metaloprotease, processo para a sua preparação e composições farmacêuticas contendo os mesmos | |
| DE69710909D1 (de) | Substituierte tetrahydropyridinderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel | |
| BR9801448A (pt) | Compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos. | |
| ATE219491T1 (de) | Acronycinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen | |
| BR0002679A (pt) | Compostos de carboxilato de 7-oxo-2,3,7,14, tetraidro-1h-benzo[b]-pirano[3,2-h]acridina, processo para a sua preparação e composições farmacêuticas contendo os mesmos | |
| BRPI9710537B8 (pt) | derivados da eritromicina, composições farmacêuticas, bem como processo para preparação dos mesmos. | |
| BR0210894A (pt) | Derivados de benzo(g) quinolina | |
| BR0213403A (pt) | Derivados de hidroxialquila indolocarbazol, o respectivo processo de preparo, e as composições farmacêuticas que os contêm | |
| BR9809578A (pt) | Esteróides 4-halogenados, seu processo e intermediários de preparação, sua aplicação como medicamentos e as composições farmacêuticas que os contêm | |
| BR9908661A (pt) | Compostos de 1,2-ditiolano, processo para sua preparação e composições farmacêuticas contendo-os | |
| BR9805014A (pt) | Inibidores de metaloproteinase, processo para sua preparação e composições farmacêuticas contendo os mesmos | |
| BRPI0500306A (pt) | Compostos de benzo[b]cromeno-naftiridin-7-ona e pirano[2',3':7,8] quino [2,3-b]quinoxalin-7-ona, processo para a sua preparação e composições farmacêuticas contendo-os |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADE(S). |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2055 DE 25/05/2010. |