CA2393045A1 - Mutant er.alpha. and test systems for transactivation - Google Patents

Mutant er.alpha. and test systems for transactivation Download PDF

Info

Publication number
CA2393045A1
CA2393045A1 CA002393045A CA2393045A CA2393045A1 CA 2393045 A1 CA2393045 A1 CA 2393045A1 CA 002393045 A CA002393045 A CA 002393045A CA 2393045 A CA2393045 A CA 2393045A CA 2393045 A1 CA2393045 A1 CA 2393045A1
Authority
CA
Canada
Prior art keywords
alpha
seq
test
mutant
era
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002393045A
Other languages
English (en)
French (fr)
Inventor
Koichi Saito
Norihisa Ohe
Hideo Satoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2393045A1 publication Critical patent/CA2393045A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Mushroom Cultivation (AREA)
CA002393045A 1999-12-07 2000-12-01 Mutant er.alpha. and test systems for transactivation Abandoned CA2393045A1 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
JP34802299 1999-12-07
JP11/348022 1999-12-07
JP37066799 1999-12-27
JP11/370667 1999-12-27
JP2000207011 2000-07-07
JP2000-207011 2000-07-07
JP2000220508 2000-07-21
JP2000-220508 2000-07-21
JP2000234053 2000-08-02
JP2000-234053 2000-08-02
JP2000235463 2000-08-03
JP2000-235460 2000-08-03
JP2000-235463 2000-08-03
JP2000-235461 2000-08-03
JP2000235460 2000-08-03
JP2000235461 2000-08-03
PCT/JP2000/008553 WO2001042307A1 (en) 1999-12-07 2000-12-01 MUTANT ERα AND TEST SYSTEMS FOR TRANSACTIVATION

Publications (1)

Publication Number Publication Date
CA2393045A1 true CA2393045A1 (en) 2001-06-14

Family

ID=27573667

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002393045A Abandoned CA2393045A1 (en) 1999-12-07 2000-12-01 Mutant er.alpha. and test systems for transactivation

Country Status (8)

Country Link
US (1) US7582476B2 (enExample)
EP (1) EP1237925B1 (enExample)
JP (1) JP4742483B2 (enExample)
AT (1) ATE366745T1 (enExample)
AU (1) AU782142B2 (enExample)
CA (1) CA2393045A1 (enExample)
DE (1) DE60035522T2 (enExample)
WO (1) WO2001042307A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057283A1 (en) * 2001-01-19 2002-07-25 Baylor College Of Medecine Methods and compositions in breast cancer diagnosis and therapeutics
WO2004005497A1 (ja) * 2002-07-02 2004-01-15 Yamanouchi Pharmaceutical Co., Ltd. インスリン抵抗性改善薬スクリーニング方法
EP2977470B1 (en) 2002-10-16 2018-01-03 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
US7927840B2 (en) 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
AU2003280793A1 (en) * 2002-11-15 2004-06-15 Sumitomo Chemical Company, Limited MUTANT ESTROGEN RECEPTOR-Alpha AND GENE THEREOF
EP1680447A2 (en) * 2003-10-24 2006-07-19 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Orthogonal gene switches
FR2863275B1 (fr) * 2003-12-09 2007-08-10 Biomerieux Sa Procede pour le diagnostic/pronostic du cancer du sein
EP1711606A2 (en) 2004-01-20 2006-10-18 Isis Pharmaceuticals, Inc. Modulation of glucocorticoid receptor expression
JP2006153656A (ja) * 2004-11-29 2006-06-15 Olympus Corp 反応カプセル、反応カプセルを使用した検査方法およびシステム
KR20140084232A (ko) 2011-10-25 2014-07-04 아이시스 파마수티컬즈 인코포레이티드 Gccr 발현의 안티센스 조절
MX2015016171A (es) 2013-06-19 2016-08-08 Seragon Pharmaceuticals Inc Moduladores del receptor de estrogeno de azetidina y usos de los mismos.
EA031077B1 (ru) 2013-06-19 2018-11-30 Серагон Фармасьютикалз, Инк. Модулятор рецептора эстрогена и его применения
BR112016020953A2 (pt) * 2014-03-13 2018-01-23 Hoffmann La Roche composto, kit, composição farmacêutica, uso de composto, método de tratamento e invenção
CN107531722B (zh) 2015-05-26 2020-07-17 豪夫迈·罗氏有限公司 杂环雌激素受体调节剂及其用途
US10179676B1 (en) 2017-07-26 2019-01-15 William Hagan Taylor Dispenser with self-closing cap

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987005049A1 (en) * 1986-02-20 1987-08-27 California Biotechnology Inc. Eucaryotic expression of steroid receptor proteins
FR2634495B1 (fr) * 1988-07-01 1990-10-26 Chambon Pierre Procede de preparation d'une proteine par des levures utilisant un systeme inductible, vecteurs et souches transformees correspondantes
AU8951191A (en) * 1990-10-29 1992-05-26 Dekalb Plant Genetics Isolation of biological materials using magnetic particles

Also Published As

Publication number Publication date
DE60035522D1 (de) 2007-08-23
JP4742483B2 (ja) 2011-08-10
AU782142B2 (en) 2005-07-07
US20030207380A1 (en) 2003-11-06
AU1886801A (en) 2001-06-18
JP2003516137A (ja) 2003-05-13
DE60035522T2 (de) 2008-03-20
EP1237925A1 (en) 2002-09-11
ATE366745T1 (de) 2007-08-15
US7582476B2 (en) 2009-09-01
WO2001042307A1 (en) 2001-06-14
EP1237925B1 (en) 2007-07-11

Similar Documents

Publication Publication Date Title
CA2393045A1 (en) Mutant er.alpha. and test systems for transactivation
JP3512797B2 (ja) 哺乳動物メラニン細胞刺激ホルモン受容体およびその使用
WO1995013373A1 (en) Ubiquitous nuclear receptor: compositions and methods
WO2002006529A2 (en) Detection and treatment of polycystic kidney disease
KR19980041692A (ko) 신규한 에스트로겐 수용체
WO1997018333A1 (en) Disruption of expression of multiple alleles of mammalian genes
Beitel et al. Complete androgen insensitivity due to mutations in the probable α-helical segments of the DNA-binding domain in the human androgen receptor
KR100828506B1 (ko) 마우스 정자 형성 유전자와 인간 남성 불임 관련 유전자,및 이들을 사용한 진단 시스템
CA2205203A1 (en) Ctcf
US6046011A (en) Mammalian adrenocorticotropic hormone receptors and uses
AU8724498A (en) 1-alpha-hydroxylase materials and methods
CA2381066A1 (en) Polymorphisms in the human hpxr gene and their use in diagnostic and therapeutic applications
US5460942A (en) The catalytic moiety of the glucose-6-phosphatase system: the gene and protein and related mutations
JP4400183B2 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
JP4400182B2 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
JP4400181B2 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
WO2004046352A1 (ja) 変異型エストロゲンレセプターαおよびその遺伝子
JP2004254600A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JP2004008141A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JP4622086B2 (ja) エストロゲンレセプター遺伝子およびその利用
JP2004254601A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JP2004008140A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
CTCF et al. Lobanenkov et al.
JP2004254602A (ja) 変異型アンドロゲンレセプターおよびその活性評価用細胞
JP2002153280A (ja) Dnaとdna結合因子との結合を促進するタンパク質およびそのタンパク質をコードする遺伝子

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20130614