CA2393045A1 - Mutant er.alpha. and test systems for transactivation - Google Patents

Mutant er.alpha. and test systems for transactivation Download PDF

Info

Publication number
CA2393045A1
CA2393045A1 CA002393045A CA2393045A CA2393045A1 CA 2393045 A1 CA2393045 A1 CA 2393045A1 CA 002393045 A CA002393045 A CA 002393045A CA 2393045 A CA2393045 A CA 2393045A CA 2393045 A1 CA2393045 A1 CA 2393045A1
Authority
CA
Canada
Prior art keywords
alpha
seq
test
mutant
era
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002393045A
Other languages
English (en)
French (fr)
Inventor
Koichi Saito
Norihisa Ohe
Hideo Satoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of CA2393045A1 publication Critical patent/CA2393045A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/721—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Mushroom Cultivation (AREA)
CA002393045A 1999-12-07 2000-12-01 Mutant er.alpha. and test systems for transactivation Abandoned CA2393045A1 (en)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
JP34802299 1999-12-07
JP11/348022 1999-12-07
JP37066799 1999-12-27
JP11/370667 1999-12-27
JP2000207011 2000-07-07
JP2000-207011 2000-07-07
JP2000220508 2000-07-21
JP2000-220508 2000-07-21
JP2000234053 2000-08-02
JP2000-234053 2000-08-02
JP2000235463 2000-08-03
JP2000-235463 2000-08-03
JP2000235460 2000-08-03
JP2000-235461 2000-08-03
JP2000-235460 2000-08-03
JP2000235461 2000-08-03
PCT/JP2000/008553 WO2001042307A1 (en) 1999-12-07 2000-12-01 MUTANT ERα AND TEST SYSTEMS FOR TRANSACTIVATION

Publications (1)

Publication Number Publication Date
CA2393045A1 true CA2393045A1 (en) 2001-06-14

Family

ID=27573667

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002393045A Abandoned CA2393045A1 (en) 1999-12-07 2000-12-01 Mutant er.alpha. and test systems for transactivation

Country Status (8)

Country Link
US (1) US7582476B2 (enExample)
EP (1) EP1237925B1 (enExample)
JP (1) JP4742483B2 (enExample)
AT (1) ATE366745T1 (enExample)
AU (1) AU782142B2 (enExample)
CA (1) CA2393045A1 (enExample)
DE (1) DE60035522T2 (enExample)
WO (1) WO2001042307A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002057283A1 (en) * 2001-01-19 2002-07-25 Baylor College Of Medecine Methods and compositions in breast cancer diagnosis and therapeutics
EP1533368A4 (en) * 2002-07-02 2006-06-21 Astellas Pharma Inc SCREENING METHOD FOR A DRUG TO IMPROVE INSULIN RESISTANCE
AU2003298605B2 (en) 2002-10-16 2007-10-18 Gen-Probe Incorporated Compositions and methods for detecting west nile virus
US7927840B2 (en) * 2006-09-11 2011-04-19 Gen Probe Incorporated Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
AU2003280793A1 (en) * 2002-11-15 2004-06-15 Sumitomo Chemical Company, Limited MUTANT ESTROGEN RECEPTOR-Alpha AND GENE THEREOF
US20070087346A1 (en) * 2003-10-24 2007-04-19 Gennaro Ciliberto Orthogonal gene switches
FR2863275B1 (fr) * 2003-12-09 2007-08-10 Biomerieux Sa Procede pour le diagnostic/pronostic du cancer du sein
WO2005071080A2 (en) 2004-01-20 2005-08-04 Isis Pharmaceuticals, Inc. Modulation of glucocorticoid receptor expression
JP2006153656A (ja) * 2004-11-29 2006-06-15 Olympus Corp 反応カプセル、反応カプセルを使用した検査方法およびシステム
AU2012328680A1 (en) 2011-10-25 2014-05-01 Ionis Pharmaceuticals, Inc. Antisense modulation of GCCR expression
BR112015030595A2 (pt) 2013-06-19 2017-07-25 Seragon Pharmaceuticals Inc moduladores de receptor de estrogênio de azetidina e usos dos mesmos
EA031077B1 (ru) 2013-06-19 2018-11-30 Серагон Фармасьютикалз, Инк. Модулятор рецептора эстрогена и его применения
MA39740A (fr) 2014-03-13 2017-01-18 Hoffmann La Roche Méthodes et compositions pour moduler des mutants du récepteur des oestrogènes
JP6768711B2 (ja) 2015-05-26 2020-10-14 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト 複素環式エストロゲン受容体モジュレーター及びその使用
US10179676B1 (en) 2017-07-26 2019-01-15 William Hagan Taylor Dispenser with self-closing cap

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0258401A4 (en) 1986-02-20 1989-06-13 California Biotechnology Inc Eucaryotic expression of steroid receptor proteins.
FR2634495B1 (fr) * 1988-07-01 1990-10-26 Chambon Pierre Procede de preparation d'une proteine par des levures utilisant un systeme inductible, vecteurs et souches transformees correspondantes
JPH06510363A (ja) * 1990-10-29 1994-11-17 ディカルブ　プラント　ジェネティクス 磁気性粒子を使用する生物学的材料の単離

Also Published As

Publication number Publication date
US7582476B2 (en) 2009-09-01
EP1237925B1 (en) 2007-07-11
EP1237925A1 (en) 2002-09-11
AU782142B2 (en) 2005-07-07
ATE366745T1 (de) 2007-08-15
JP2003516137A (ja) 2003-05-13
WO2001042307A1 (en) 2001-06-14
DE60035522D1 (de) 2007-08-23
US20030207380A1 (en) 2003-11-06
JP4742483B2 (ja) 2011-08-10
AU1886801A (en) 2001-06-18
DE60035522T2 (de) 2008-03-20

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20130614