CA2360932A1 - A surface plasmon resonance sensor - Google Patents
A surface plasmon resonance sensor Download PDFInfo
- Publication number
- CA2360932A1 CA2360932A1 CA002360932A CA2360932A CA2360932A1 CA 2360932 A1 CA2360932 A1 CA 2360932A1 CA 002360932 A CA002360932 A CA 002360932A CA 2360932 A CA2360932 A CA 2360932A CA 2360932 A1 CA2360932 A1 CA 2360932A1
- Authority
- CA
- Canada
- Prior art keywords
- optical
- light beam
- plasmon resonance
- exterior surface
- light
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000002198 surface plasmon resonance spectroscopy Methods 0.000 title claims abstract description 37
- 230000003287 optical effect Effects 0.000 claims abstract description 201
- 229910052751 metal Inorganic materials 0.000 claims description 67
- 239000002184 metal Substances 0.000 claims description 67
- 239000007787 solid Substances 0.000 claims description 12
- 239000004065 semiconductor Substances 0.000 claims description 9
- 238000000576 coating method Methods 0.000 claims description 7
- 230000000295 complement effect Effects 0.000 claims description 7
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 claims description 7
- 229910052737 gold Inorganic materials 0.000 claims description 7
- 239000010931 gold Substances 0.000 claims description 7
- 239000011248 coating agent Substances 0.000 claims description 5
- 239000004020 conductor Substances 0.000 claims description 5
- 229910044991 metal oxide Inorganic materials 0.000 claims description 5
- 150000004706 metal oxides Chemical class 0.000 claims description 5
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims description 4
- 229910052782 aluminium Inorganic materials 0.000 claims description 4
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims description 4
- 239000003989 dielectric material Substances 0.000 claims description 4
- 229910052709 silver Inorganic materials 0.000 claims description 4
- 239000004332 silver Substances 0.000 claims description 4
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 3
- 229910052719 titanium Inorganic materials 0.000 claims description 3
- 239000010936 titanium Substances 0.000 claims description 3
- 238000003491 array Methods 0.000 abstract description 14
- 239000010408 film Substances 0.000 description 71
- 238000000926 separation method Methods 0.000 description 18
- 230000000875 corresponding effect Effects 0.000 description 17
- 238000000034 method Methods 0.000 description 13
- 239000000523 sample Substances 0.000 description 13
- 239000012491 analyte Substances 0.000 description 12
- 230000008878 coupling Effects 0.000 description 9
- 238000010168 coupling process Methods 0.000 description 9
- 238000005859 coupling reaction Methods 0.000 description 9
- 239000011521 glass Substances 0.000 description 8
- 230000004044 response Effects 0.000 description 8
- 239000000499 gel Substances 0.000 description 7
- 229920005597 polymer membrane Polymers 0.000 description 7
- 238000006073 displacement reaction Methods 0.000 description 6
- 239000012528 membrane Substances 0.000 description 6
- 210000004379 membrane Anatomy 0.000 description 6
- 239000000126 substance Substances 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 230000005540 biological transmission Effects 0.000 description 5
- 230000008859 change Effects 0.000 description 5
- 238000013461 design Methods 0.000 description 5
- -1 for example Substances 0.000 description 5
- 239000002555 ionophore Substances 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 238000012544 monitoring process Methods 0.000 description 5
- 239000000758 substrate Substances 0.000 description 5
- 230000001131 transforming effect Effects 0.000 description 5
- 239000013598 vector Substances 0.000 description 5
- 239000000427 antigen Substances 0.000 description 4
- 238000006243 chemical reaction Methods 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 238000009396 hybridization Methods 0.000 description 4
- 239000000017 hydrogel Substances 0.000 description 4
- 230000003993 interaction Effects 0.000 description 4
- 230000000236 ionophoric effect Effects 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 230000010287 polarization Effects 0.000 description 4
- 238000012545 processing Methods 0.000 description 4
- 230000001902 propagating effect Effects 0.000 description 4
- 238000002310 reflectometry Methods 0.000 description 4
- 108091034117 Oligonucleotide Proteins 0.000 description 3
- 102000036639 antigens Human genes 0.000 description 3
- 108091007433 antigens Proteins 0.000 description 3
- 230000014509 gene expression Effects 0.000 description 3
- 230000010354 integration Effects 0.000 description 3
- 238000005259 measurement Methods 0.000 description 3
- 229920000136 polysorbate Polymers 0.000 description 3
- 229940009188 silver Drugs 0.000 description 3
- KLZUFWVZNOTSEM-UHFFFAOYSA-K Aluminium flouride Chemical compound F[Al](F)F KLZUFWVZNOTSEM-UHFFFAOYSA-K 0.000 description 2
- 101100004392 Arabidopsis thaliana BHLH147 gene Proteins 0.000 description 2
- 229920002307 Dextran Polymers 0.000 description 2
- 241000725303 Human immunodeficiency virus Species 0.000 description 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 229910052729 chemical element Inorganic materials 0.000 description 2
- 239000002299 complementary DNA Substances 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 125000000524 functional group Chemical group 0.000 description 2
- 229910001635 magnesium fluoride Inorganic materials 0.000 description 2
- 150000002739 metals Chemical class 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000007639 printing Methods 0.000 description 2
- 238000004544 sputter deposition Methods 0.000 description 2
- 230000008093 supporting effect Effects 0.000 description 2
- 239000012780 transparent material Substances 0.000 description 2
- 229920000936 Agarose Polymers 0.000 description 1
- 101710132601 Capsid protein Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 244000089409 Erythrina poeppigiana Species 0.000 description 1
- 229910001218 Gallium arsenide Inorganic materials 0.000 description 1
- 241001082241 Lythrum hyssopifolia Species 0.000 description 1
- 241001508691 Martes zibellina Species 0.000 description 1
- 239000004697 Polyetherimide Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- 235000009776 Rathbunia alamosensis Nutrition 0.000 description 1
- 229920002125 Sokalan® Polymers 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000000783 alginic acid Substances 0.000 description 1
- 235000010443 alginic acid Nutrition 0.000 description 1
- 229920000615 alginic acid Polymers 0.000 description 1
- 229960001126 alginic acid Drugs 0.000 description 1
- 150000004781 alginic acids Chemical class 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 229910001632 barium fluoride Inorganic materials 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 description 1
- 229910001634 calcium fluoride Inorganic materials 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 description 1
- 239000000679 carrageenan Substances 0.000 description 1
- 235000010418 carrageenan Nutrition 0.000 description 1
- 229940113118 carrageenan Drugs 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 235000010980 cellulose Nutrition 0.000 description 1
- 238000000658 coextraction Methods 0.000 description 1
- 229940000425 combination drug Drugs 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 229960002086 dextran Drugs 0.000 description 1
- 238000007516 diamond turning Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 239000007888 film coating Substances 0.000 description 1
- 238000009501 film coating Methods 0.000 description 1
- 238000004401 flow injection analysis Methods 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 238000001215 fluorescent labelling Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000007641 inkjet printing Methods 0.000 description 1
- 238000005342 ion exchange Methods 0.000 description 1
- FZWBNHMXJMCXLU-BLAUPYHCSA-N isomaltotriose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)O1 FZWBNHMXJMCXLU-BLAUPYHCSA-N 0.000 description 1
- 239000003446 ligand Substances 0.000 description 1
- 239000004973 liquid crystal related substance Substances 0.000 description 1
- 238000001459 lithography Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000001883 metal evaporation Methods 0.000 description 1
- MYWBZQJIXVRCJC-UHFFFAOYSA-N n-[9-(diethylamino)benzo[a]phenoxazin-5-ylidene]octadecanamide Chemical compound C12=CC=CC=C2C(=NC(=O)CCCCCCCCCCCCCCCCC)C=C2C1=NC1=CC=C(N(CC)CC)C=C1O2 MYWBZQJIXVRCJC-UHFFFAOYSA-N 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 229920000620 organic polymer Polymers 0.000 description 1
- 229920002120 photoresistant polymer Polymers 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 239000004584 polyacrylic acid Substances 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920006254 polymer film Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 150000004804 polysaccharides Chemical class 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 229920005749 polyurethane resin Polymers 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 238000004886 process control Methods 0.000 description 1
- 238000002331 protein detection Methods 0.000 description 1
- 229910052594 sapphire Inorganic materials 0.000 description 1
- 239000010980 sapphire Substances 0.000 description 1
- 229910052710 silicon Inorganic materials 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 230000003595 spectral effect Effects 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 229940032147 starch Drugs 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 229920001059 synthetic polymer Polymers 0.000 description 1
- 229910052715 tantalum Inorganic materials 0.000 description 1
- GUVRBAGPIYLISA-UHFFFAOYSA-N tantalum atom Chemical compound [Ta] GUVRBAGPIYLISA-UHFFFAOYSA-N 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 150000003573 thiols Chemical class 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/55—Specular reflectivity
- G01N21/552—Attenuated total reflection
- G01N21/553—Attenuated total reflection and using surface plasmons
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11811199P | 1999-02-01 | 1999-02-01 | |
| DKPA199900118 | 1999-02-01 | ||
| US60/118,111 | 1999-02-01 | ||
| DKPA199900118 | 1999-02-01 | ||
| PCT/DK2000/000036 WO2000046589A1 (en) | 1999-02-01 | 2000-01-28 | A surface plasmon resonance sensor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2360932A1 true CA2360932A1 (en) | 2000-08-10 |
Family
ID=26063351
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002360932A Abandoned CA2360932A1 (en) | 1999-02-01 | 2000-01-28 | A surface plasmon resonance sensor |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1157266A1 (zh) |
| JP (1) | JP2002536638A (zh) |
| KR (1) | KR20010110428A (zh) |
| CN (1) | CN1344366A (zh) |
| AU (1) | AU771594B2 (zh) |
| CA (1) | CA2360932A1 (zh) |
| NZ (1) | NZ513843A (zh) |
| WO (1) | WO2000046589A1 (zh) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103712954A (zh) * | 2013-12-27 | 2014-04-09 | 中国科学院苏州生物医学工程技术研究所 | 一种用于筛选抗肿瘤药物的spr传感芯片的制备方法 |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2407721A1 (en) | 2000-07-21 | 2002-01-31 | Vir A/S | Coupling elements for surface plasmon resonance sensors |
| JP2002296176A (ja) * | 2001-01-25 | 2002-10-09 | Fuji Photo Film Co Ltd | 全反射減衰を利用したセンサー |
| WO2002066162A1 (en) * | 2001-02-16 | 2002-08-29 | Vir A/S | Method for the preparation of optical (bio)chemical sensor devices |
| JP3945636B2 (ja) * | 2001-03-27 | 2007-07-18 | 富士フイルム株式会社 | 測定装置 |
| DE10151312C2 (de) * | 2001-10-17 | 2003-08-28 | Vir As Taastrup | Oberflächenplasmonen-Resonanz-Sensor |
| NL1019317C2 (nl) * | 2001-11-06 | 2003-05-07 | Tno | Detectie van een geladen deeltje. |
| DE10163657B4 (de) | 2001-12-21 | 2008-05-08 | Gedig, Erk, Dr. | Vorrichtung und Verfahren zur Untersuchung dünner Schichten |
| EP1509760A1 (en) | 2002-05-31 | 2005-03-02 | Gyros AB | Detector arrangement based on surface plasmon resonance |
| AU2003280323A1 (en) * | 2002-11-18 | 2004-06-15 | Vir A/S | Dispersion compensating biosensor |
| NL1022916C2 (nl) * | 2003-03-13 | 2004-09-14 | Ssens B V | Toestel en werkwijze voor onderzoek van een dunne laag opbouw gebruik makend van oppervlakte plasmon resonantie en inrichting en werkwijze voor het regelen van temperatuur. |
| US7994877B1 (en) | 2008-11-10 | 2011-08-09 | Hrl Laboratories, Llc | MEMS-based quartz hybrid filters and a method of making the same |
| DE10324973B4 (de) * | 2003-05-27 | 2006-04-13 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anordnung und Verfahren zur optischen Detektion von in Proben enthaltenen chemischen, biochemischen Molekülen und/oder Partikeln |
| US7002688B2 (en) * | 2003-10-16 | 2006-02-21 | Pria Diagnostics, Inc. | Multilens optical assembly for a diagnostic device |
| CN1894576B (zh) | 2003-11-19 | 2010-04-28 | 比恩诺尔股份公司 | 用于执行表面等离子共振测量的方法和装置 |
| WO2006030957A1 (en) * | 2004-09-16 | 2006-03-23 | Canon Kabushiki Kaisha | Device and method for acquiring information on objective substance to be detected by detecting a change of wavelenght characteristics on the optical transmittance |
| JP2006171479A (ja) * | 2004-12-17 | 2006-06-29 | Ricoh Co Ltd | 変換素子 |
| CN100520394C (zh) * | 2005-03-08 | 2009-07-29 | 中国科学院电子学研究所 | 一种单通道多参数表面等离子体谐振测试仪 |
| JP4481967B2 (ja) * | 2005-09-05 | 2010-06-16 | キヤノン株式会社 | センサ装置 |
| JP2007101241A (ja) * | 2005-09-30 | 2007-04-19 | Fujifilm Corp | センシング装置 |
| JP4893032B2 (ja) | 2006-03-15 | 2012-03-07 | オムロン株式会社 | 光学部品、光学センサ及び表面プラズモンセンサ |
| US7592826B1 (en) * | 2006-05-31 | 2009-09-22 | Lockheed Martin Corporation | Method and apparatus for detecting EM energy using surface plasmon polaritons |
| PT103606B (pt) | 2006-11-15 | 2009-03-16 | Biosurfit Sa | Dispositivo de detecção dinâmico baseado no efeito de ressonância de plasmão de superfície |
| US7884930B2 (en) | 2007-06-14 | 2011-02-08 | Hrl Laboratories, Llc | Integrated quartz biological sensor and method |
| US20100020311A1 (en) * | 2007-06-14 | 2010-01-28 | Hrl Laboratories, Llc | Integrated quartz biological sensor and method |
| TW200902954A (en) * | 2007-07-13 | 2009-01-16 | Univ Nat Taiwan | Miniaturized surface plasmon resonance sensing chip |
| US10266398B1 (en) | 2007-07-25 | 2019-04-23 | Hrl Laboratories, Llc | ALD metal coatings for high Q MEMS structures |
| DE102007036492B4 (de) * | 2007-08-01 | 2009-07-30 | Trw Automotive Electronics & Components Gmbh & Co. Kg | Optische Sensorvorrichtung |
| JP5107003B2 (ja) * | 2007-11-22 | 2012-12-26 | パナソニックヘルスケア株式会社 | エバネッセント波発生装置及びそれを用いた観察装置 |
| JP2010025580A (ja) * | 2008-07-15 | 2010-02-04 | Olympus Corp | 光学ユニット |
| GB0919742D0 (en) * | 2009-11-11 | 2009-12-30 | Millipore Corp | Optical sensor |
| US8912711B1 (en) | 2010-06-22 | 2014-12-16 | Hrl Laboratories, Llc | Thermal stress resistant resonator, and a method for fabricating same |
| US10768108B2 (en) | 2011-09-28 | 2020-09-08 | Ge Healthcare Bio-Sciences Ab | Surface plasmon resonance biosensor system |
| AU2014364006B2 (en) * | 2013-12-10 | 2019-07-11 | Illumina, Inc. | Biosensors for biological or chemical analysis and methods of manufacturing the same |
| JP6313054B2 (ja) * | 2014-01-29 | 2018-04-18 | 京セラ株式会社 | 光センサモジュールおよび光センサ装置 |
| US9977097B1 (en) | 2014-02-21 | 2018-05-22 | Hrl Laboratories, Llc | Micro-scale piezoelectric resonating magnetometer |
| US9991863B1 (en) | 2014-04-08 | 2018-06-05 | Hrl Laboratories, Llc | Rounded and curved integrated tethers for quartz resonators |
| US10308505B1 (en) | 2014-08-11 | 2019-06-04 | Hrl Laboratories, Llc | Method and apparatus for the monolithic encapsulation of a micro-scale inertial navigation sensor suite |
| US10031191B1 (en) | 2015-01-16 | 2018-07-24 | Hrl Laboratories, Llc | Piezoelectric magnetometer capable of sensing a magnetic field in multiple vectors |
| JP6458056B2 (ja) * | 2015-01-26 | 2019-01-23 | 株式会社日立ハイテクノロジーズ | 光学的分析装置 |
| EP3321663B1 (en) * | 2015-07-07 | 2021-03-24 | Furuno Electric Co., Ltd. | Measuring chip, measurement device, and measurement method |
| US10110198B1 (en) | 2015-12-17 | 2018-10-23 | Hrl Laboratories, Llc | Integrated quartz MEMS tuning fork resonator/oscillator |
| US10175307B1 (en) | 2016-01-15 | 2019-01-08 | Hrl Laboratories, Llc | FM demodulation system for quartz MEMS magnetometer |
| CN111366998B (zh) * | 2020-03-16 | 2022-04-01 | 国家纳米科学中心 | 一种等离子体激元激子杂化结构及其制备方法和应用 |
| GB202010010D0 (en) * | 2020-06-30 | 2020-08-12 | Ams Int Ag | Imaging surface plasmon resonance apparatus |
| US11486825B1 (en) * | 2022-06-07 | 2022-11-01 | The Florida International University Board Of Trustees | Devices and methods for analysis of biological matter using plasmon resonance |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE462408B (sv) * | 1988-11-10 | 1990-06-18 | Pharmacia Ab | Optiskt biosensorsystem utnyttjande ytplasmonresonans foer detektering av en specific biomolekyl, saett att kalibrera sensoranordningen samt saett att korrigera foer baslinjedrift i systemet |
| AU7598996A (en) * | 1995-10-25 | 1997-05-15 | University Of Washington | Surface plasmon resonance probe systems based on a folded planar lightpipe |
| EP0797091A1 (en) * | 1996-03-19 | 1997-09-24 | Texas Instruments Incorporated | Surface plasmon resonance sensor with interchangable optical element |
| EP0863395B1 (en) * | 1997-02-07 | 2005-06-15 | Fuji Photo Film Co., Ltd. | Surface plasmon sensor |
-
2000
- 2000-01-28 NZ NZ513843A patent/NZ513843A/en unknown
- 2000-01-28 AU AU22785/00A patent/AU771594B2/en not_active Ceased
- 2000-01-28 CA CA002360932A patent/CA2360932A1/en not_active Abandoned
- 2000-01-28 CN CN00805379A patent/CN1344366A/zh active Pending
- 2000-01-28 KR KR1020017009709A patent/KR20010110428A/ko not_active Application Discontinuation
- 2000-01-28 JP JP2000597621A patent/JP2002536638A/ja active Pending
- 2000-01-28 EP EP00901485A patent/EP1157266A1/en not_active Withdrawn
- 2000-01-28 WO PCT/DK2000/000036 patent/WO2000046589A1/en not_active Application Discontinuation
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103712954A (zh) * | 2013-12-27 | 2014-04-09 | 中国科学院苏州生物医学工程技术研究所 | 一种用于筛选抗肿瘤药物的spr传感芯片的制备方法 |
| CN103712954B (zh) * | 2013-12-27 | 2016-02-03 | 中国科学院苏州生物医学工程技术研究所 | 一种用于筛选抗肿瘤药物的spr传感芯片的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU771594B2 (en) | 2004-03-25 |
| JP2002536638A (ja) | 2002-10-29 |
| AU2278500A (en) | 2000-08-25 |
| NZ513843A (en) | 2002-07-26 |
| WO2000046589A1 (en) | 2000-08-10 |
| EP1157266A1 (en) | 2001-11-28 |
| KR20010110428A (ko) | 2001-12-13 |
| CN1344366A (zh) | 2002-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU771594B2 (en) | A surface plasmon resonance sensor | |
| US6738141B1 (en) | Surface plasmon resonance sensor | |
| US10274432B1 (en) | Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats | |
| US5986762A (en) | Optical sensor having optimized surface profile | |
| US6714303B2 (en) | Analytical method and apparatus | |
| US6100991A (en) | Near normal incidence optical assaying method and system having wavelength and angle sensitivity | |
| EP1121583B1 (en) | Optical sensor having dielectric film stack | |
| US5925878A (en) | Diffraction anomaly sensor having grating coated with protective dielectric layer | |
| Piliarik et al. | SPR sensor instrumentation | |
| US7218401B2 (en) | Surface plasmon sensor, surface plasmon resonance measurement device, and detection chip | |
| KR101109148B1 (ko) | 표면 플라즈몬 공진 센서 및 표면 플라즈몬 공진을 이용한 센싱 방법 | |
| US20040114145A1 (en) | Dispersion compensating biosensor | |
| Ligler et al. | INTERFEROMETRIC BIOSENSORS | |
| Piliarik | High-Throughput Biosensor Based on Surface Plasmon Resonance Imaging |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued | ||
| FZDE | Discontinued |
Effective date: 20060130 |