CA2359234C - A method for labeled conjugate production - Google Patents

A method for labeled conjugate production Download PDF

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Publication number
CA2359234C
CA2359234C CA2359234A CA2359234A CA2359234C CA 2359234 C CA2359234 C CA 2359234C CA 2359234 A CA2359234 A CA 2359234A CA 2359234 A CA2359234 A CA 2359234A CA 2359234 C CA2359234 C CA 2359234C
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CA
Canada
Prior art keywords
label
nhs
reagent
target moiety
reductant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2359234A
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English (en)
French (fr)
Other versions
CA2359234A1 (en
Inventor
John P. Morseman
Xiangfei Zeng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Martek Biosciences Corp
Original Assignee
Martek Biosciences Corp
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Publication date
Application filed by Martek Biosciences Corp filed Critical Martek Biosciences Corp
Publication of CA2359234A1 publication Critical patent/CA2359234A1/en
Application granted granted Critical
Publication of CA2359234C publication Critical patent/CA2359234C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals

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  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
CA2359234A 1999-01-22 2000-01-21 A method for labeled conjugate production Expired - Fee Related CA2359234C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11668999P 1999-01-22 1999-01-22
US60/116,689 1999-01-22
PCT/US2000/001350 WO2000043784A1 (en) 1999-01-22 2000-01-21 Simple method for labeled conjugate production

Publications (2)

Publication Number Publication Date
CA2359234A1 CA2359234A1 (en) 2000-07-27
CA2359234C true CA2359234C (en) 2011-11-15

Family

ID=22368643

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2359234A Expired - Fee Related CA2359234C (en) 1999-01-22 2000-01-21 A method for labeled conjugate production

Country Status (7)

Country Link
EP (1) EP1145007B1 (https=)
JP (1) JP4731018B2 (https=)
AT (1) ATE286250T1 (https=)
AU (1) AU771248B2 (https=)
CA (1) CA2359234C (https=)
DE (1) DE60017083T2 (https=)
WO (1) WO2000043784A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005015212A1 (en) * 2003-08-07 2005-02-17 Cellfree Sciences Co., Ltd. Reagent for producing a protein chip
GB2478359B (en) * 2010-03-05 2018-09-12 Innova Biosciences Ltd Conjugation reactions
US8877892B2 (en) 2011-03-15 2014-11-04 Innova Biosciences Limited Conjugation reactions
JP2017083461A (ja) * 2016-12-21 2017-05-18 イノーバ・バイオサイエンシズ・リミテッドＩｎｎｏｖａ Ｂｉｏｓｃｉｅｎｃｅｓ Ｌｔｄ 共役反応
CN109490298B (zh) * 2018-12-04 2021-02-02 郑州大学 一种可视化偶联反应试剂盒
CN110108868B (zh) * 2019-05-27 2022-09-06 蓝怡科技集团股份有限公司 一种酶标记的方法及其应用
CN111044732A (zh) * 2019-12-27 2020-04-21 桂林优利特医疗电子有限公司 用于流式细胞仪法cd45抗原检测的试剂盒及其制备方法
CN114354950A (zh) * 2022-01-18 2022-04-15 北京易斯威特生物科技股份有限公司 一种性激素功能联合检测用试纸条、制备方法及其应用
CN114539368B (zh) * 2022-02-16 2023-08-29 上海万子健生物科技有限公司 一种链霉亲和素藻红蛋白冻干粉的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4732864A (en) * 1983-10-06 1988-03-22 E. I. Du Pont De Nemours And Company Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
US5202451A (en) * 1988-02-17 1993-04-13 Neorx Corporation Anchimeric radiometal chelating compounds
JP2731613B2 (ja) * 1989-12-12 1998-03-25 株式会社クラレ 酵素免疫測定用カートリツジ、それを用いた測定方法及び測定装置
CA2168283A1 (en) * 1996-01-29 1997-07-30 John Michael Lee Preparation of biological material for implants
EP0880704B1 (en) * 1996-07-18 2003-09-24 Dade Behring Marburg GmbH Reagents for assays for mycophenolic acid

Also Published As

Publication number Publication date
EP1145007A1 (en) 2001-10-17
WO2000043784A1 (en) 2000-07-27
ATE286250T1 (de) 2005-01-15
JP2002535657A (ja) 2002-10-22
CA2359234A1 (en) 2000-07-27
AU2511800A (en) 2000-08-07
JP4731018B2 (ja) 2011-07-20
DE60017083T2 (de) 2005-12-22
EP1145007B1 (en) 2004-12-29
AU771248B2 (en) 2004-03-18
DE60017083D1 (de) 2005-02-03

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Effective date: 20140121