CA2328252A1 - Ligands de recepteur - Google Patents

Ligands de recepteur Download PDF

Info

Publication number
CA2328252A1
CA2328252A1 CA002328252A CA2328252A CA2328252A1 CA 2328252 A1 CA2328252 A1 CA 2328252A1 CA 002328252 A CA002328252 A CA 002328252A CA 2328252 A CA2328252 A CA 2328252A CA 2328252 A1 CA2328252 A1 CA 2328252A1
Authority
CA
Canada
Prior art keywords
receptor
cis
trans
multimeric
independently
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002328252A
Other languages
English (en)
Inventor
Katherine Louisa Widdowson
Martin Rosenberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2328252A1 publication Critical patent/CA2328252A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/12—Saturated polycyclic compounds
    • C07C61/125—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system
    • C07C61/13—Saturated polycyclic compounds having a carboxyl group bound to a condensed ring system having two rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

L'invention concerne des ligands de récepteur multimères, non anticorps, leurs procédés de fabrication et d'identification et leur utilisation comme récepteurs multimères antagonistes ou agonistes.
CA002328252A 1998-04-14 1998-04-14 Ligands de recepteur Abandoned CA2328252A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/007389 WO1999052877A1 (fr) 1998-04-14 1998-04-14 Ligands de recepteur

Publications (1)

Publication Number Publication Date
CA2328252A1 true CA2328252A1 (fr) 1999-10-21

Family

ID=22266829

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002328252A Abandoned CA2328252A1 (fr) 1998-04-14 1998-04-14 Ligands de recepteur

Country Status (4)

Country Link
EP (1) EP1071667A4 (fr)
JP (1) JP2002511569A (fr)
CA (1) CA2328252A1 (fr)
WO (1) WO1999052877A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001025277A1 (fr) * 1999-10-07 2001-04-12 Maxygen Aps Polypeptides antagonistes a chaine unique
GB0201679D0 (en) * 2002-01-25 2002-03-13 Asterion Ltd Polypeptide variants
FR2840307B1 (fr) * 2002-05-30 2006-07-07 Centre Nat Rech Scient Nouvelles molecules multimeriques, leur procede de preparation, et leur utilisation pour la preparation de medicaments
US7998481B2 (en) 2004-04-05 2011-08-16 The Regents Of The University Of California Modulation of NKG2D for treating or preventing solid organ allograft rejection
JP2008509692A (ja) * 2004-08-16 2008-04-03 ノボ ノルディスク アクティーゼルスカブ ペプチドの多量体
FR2879202B1 (fr) 2004-12-15 2007-02-23 Centre Nat Rech Scient Cnrse Nouveaux ligands multimeriques de cd40, leur procede de preparation et leur utilisation pour la preparation de medicaments

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3361716A (en) * 1962-02-01 1968-01-02 Du Pont Polyesters of decahydro-bis-(hydroxy-methyl)-naphthalene
US3271365A (en) * 1962-11-05 1966-09-06 Du Pont Polyesters of decahydronaphthalenedicarboxylic acid and dihydric phenols
EA001220B1 (ru) * 1995-06-07 2000-12-25 Глаксо Груп Лимитед Пептид или пептидомиметик, который связывается с рецептором тромбоэтина, фармацевтическая композиция и способ лечения
EP0920314B1 (fr) * 1996-05-22 2003-08-27 Smithkline Beecham Corporation Mimetique du g-csf non peptidique
AU739173B2 (en) * 1997-10-31 2001-10-04 Ligand Pharmaceuticals Incorporated Novel metal complexes

Also Published As

Publication number Publication date
WO1999052877A1 (fr) 1999-10-21
EP1071667A4 (fr) 2004-10-20
JP2002511569A (ja) 2002-04-16
EP1071667A1 (fr) 2001-01-31

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Legal Events

Date Code Title Description
FZDE Discontinued