CA2324566A1 - Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment - Google Patents
Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment Download PDFInfo
- Publication number
- CA2324566A1 CA2324566A1 CA002324566A CA2324566A CA2324566A1 CA 2324566 A1 CA2324566 A1 CA 2324566A1 CA 002324566 A CA002324566 A CA 002324566A CA 2324566 A CA2324566 A CA 2324566A CA 2324566 A1 CA2324566 A1 CA 2324566A1
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- carbon atoms
- pharmaceutical composition
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- Prior art date
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- 235000002906 tartaric acid Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 125000000335 thiazolyl group Chemical group 0.000 description 1
- 125000001544 thienyl group Chemical group 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- 125000003774 valeryl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 230000003245 working effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10/72280 | 1998-03-20 | ||
| JP7228098 | 1998-03-20 | ||
| PCT/JP1999/001335 WO1999048522A1 (en) | 1998-03-20 | 1999-03-17 | Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2324566A1 true CA2324566A1 (en) | 1999-09-30 |
Family
ID=13484725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002324566A Abandoned CA2324566A1 (en) | 1998-03-20 | 1999-03-17 | Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6342531B1 (enExample) |
| EP (1) | EP1064021B1 (enExample) |
| JP (1) | JP2002507579A (enExample) |
| KR (1) | KR20010041967A (enExample) |
| CN (1) | CN1301173A (enExample) |
| AR (1) | AR018784A1 (enExample) |
| AT (1) | ATE275420T1 (enExample) |
| AU (1) | AU2852699A (enExample) |
| BR (1) | BR9908948A (enExample) |
| CA (1) | CA2324566A1 (enExample) |
| DE (1) | DE69919995T2 (enExample) |
| ES (1) | ES2224613T3 (enExample) |
| HU (1) | HUP0101428A2 (enExample) |
| ID (1) | ID27507A (enExample) |
| MX (1) | MXPA00009188A (enExample) |
| MY (1) | MY133063A (enExample) |
| NO (1) | NO20004679L (enExample) |
| PL (1) | PL342970A1 (enExample) |
| WO (1) | WO1999048522A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7766300A (en) * | 1999-10-07 | 2001-05-10 | Novaneuron Inc. | Gene necessary for striatal function, uses thereof, and compounds for modulatingsame |
| JPWO2002034252A1 (ja) | 2000-10-26 | 2004-03-04 | 千寿製薬株式会社 | ジペプチジルアルデヒド誘導体含有医薬組成物 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992011850A2 (en) | 1990-12-28 | 1992-07-23 | Cortex Pharmaceuticals, Inc. | Use of calpain inhibitors in the inhibition and treatment of neurodegeneration |
| ATE239698T1 (de) | 1995-10-25 | 2003-05-15 | Senju Pharma Co | Angiogenese hemmer |
-
1999
- 1999-03-17 MY MYPI99000998A patent/MY133063A/en unknown
- 1999-03-17 PL PL99342970A patent/PL342970A1/xx not_active Application Discontinuation
- 1999-03-17 WO PCT/JP1999/001335 patent/WO1999048522A1/en not_active Ceased
- 1999-03-17 HU HU0101428A patent/HUP0101428A2/hu unknown
- 1999-03-17 JP JP2000537569A patent/JP2002507579A/ja not_active Ceased
- 1999-03-17 EP EP99909212A patent/EP1064021B1/en not_active Expired - Lifetime
- 1999-03-17 MX MXPA00009188A patent/MXPA00009188A/es unknown
- 1999-03-17 US US09/646,529 patent/US6342531B1/en not_active Expired - Fee Related
- 1999-03-17 CA CA002324566A patent/CA2324566A1/en not_active Abandoned
- 1999-03-17 AT AT99909212T patent/ATE275420T1/de not_active IP Right Cessation
- 1999-03-17 DE DE69919995T patent/DE69919995T2/de not_active Expired - Lifetime
- 1999-03-17 BR BR9908948-3A patent/BR9908948A/pt not_active Application Discontinuation
- 1999-03-17 ID IDW20002104A patent/ID27507A/id unknown
- 1999-03-17 ES ES99909212T patent/ES2224613T3/es not_active Expired - Lifetime
- 1999-03-17 KR KR1020007010291A patent/KR20010041967A/ko not_active Withdrawn
- 1999-03-17 AU AU28526/99A patent/AU2852699A/en not_active Abandoned
- 1999-03-17 CN CN99806167A patent/CN1301173A/zh active Pending
- 1999-03-19 AR ARP990101215A patent/AR018784A1/es unknown
-
2000
- 2000-09-19 NO NO20004679A patent/NO20004679L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PL342970A1 (en) | 2001-07-16 |
| MXPA00009188A (es) | 2002-04-24 |
| EP1064021B1 (en) | 2004-09-08 |
| ES2224613T3 (es) | 2005-03-01 |
| ID27507A (id) | 2001-04-12 |
| KR20010041967A (ko) | 2001-05-25 |
| NO20004679D0 (no) | 2000-09-19 |
| ATE275420T1 (de) | 2004-09-15 |
| DE69919995D1 (de) | 2004-10-14 |
| DE69919995T2 (de) | 2005-09-22 |
| US6342531B1 (en) | 2002-01-29 |
| AR018784A1 (es) | 2001-12-12 |
| BR9908948A (pt) | 2000-11-21 |
| MY133063A (en) | 2007-10-31 |
| WO1999048522A1 (en) | 1999-09-30 |
| JP2002507579A (ja) | 2002-03-12 |
| NO20004679L (no) | 2000-10-26 |
| EP1064021A1 (en) | 2001-01-03 |
| CN1301173A (zh) | 2001-06-27 |
| AU2852699A (en) | 1999-10-18 |
| HUP0101428A2 (hu) | 2001-09-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |