BR9908948A - Composição farmacêutica contendo um inibidor de protease cisteìna para profilaxia e terapia de dano ao tecido cerebral - Google Patents
Composição farmacêutica contendo um inibidor de protease cisteìna para profilaxia e terapia de dano ao tecido cerebralInfo
- Publication number
- BR9908948A BR9908948A BR9908948-3A BR9908948A BR9908948A BR 9908948 A BR9908948 A BR 9908948A BR 9908948 A BR9908948 A BR 9908948A BR 9908948 A BR9908948 A BR 9908948A
- Authority
- BR
- Brazil
- Prior art keywords
- prophylaxis
- therapy
- pharmaceutical composition
- damage
- composition containing
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Patente de Invenção: <B>"COMPOSIçãO FARMACêUTICA CONTENDO UM INIBIDOR DE PROTEASE CISTEìNA PARA PROFILAXIA E TERAPIA DE DANO AO TECIDO CEREBRAL"<D>. Composição farmacêutica para profilaxia e terapia de dano ao tecido cerebral, que contém, como um ingrediente ativo, um composto de fórmula (I), onde R¹ representa um grupo alquila com 1-4 átomos de carbono ou um grupo arila com 6-10 átomos de carbono, que é opcionalmente substituído; R² e R³ podem ser iguais ou diferentes, e cada um representa hidrogênio ou um grupo alquila com 1-4 átomos de carbono ou R² e R³ podem, unidos formar um anel com 3-7 átomos de carbono; R^ 4^ representa um grupo alquila inferior que é opcionalmente substituído com arila, cicloalquila, ou resíduo heterocíclico aromático, ou um sal farmaceuticamente aceitável do mesmo.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7228098 | 1998-03-20 | ||
| PCT/JP1999/001335 WO1999048522A1 (en) | 1998-03-20 | 1999-03-17 | Pharmaceutical composition containing a cysteine protease inhibitor for prophylaxis and therapy of brain tissue impairment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9908948A true BR9908948A (pt) | 2000-11-21 |
Family
ID=13484725
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9908948-3A BR9908948A (pt) | 1998-03-20 | 1999-03-17 | Composição farmacêutica contendo um inibidor de protease cisteìna para profilaxia e terapia de dano ao tecido cerebral |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6342531B1 (pt) |
| EP (1) | EP1064021B1 (pt) |
| JP (1) | JP2002507579A (pt) |
| KR (1) | KR20010041967A (pt) |
| CN (1) | CN1301173A (pt) |
| AR (1) | AR018784A1 (pt) |
| AT (1) | ATE275420T1 (pt) |
| AU (1) | AU2852699A (pt) |
| BR (1) | BR9908948A (pt) |
| CA (1) | CA2324566A1 (pt) |
| DE (1) | DE69919995T2 (pt) |
| ES (1) | ES2224613T3 (pt) |
| HU (1) | HUP0101428A2 (pt) |
| ID (1) | ID27507A (pt) |
| MX (1) | MXPA00009188A (pt) |
| MY (1) | MY133063A (pt) |
| NO (1) | NO20004679L (pt) |
| PL (1) | PL342970A1 (pt) |
| WO (1) | WO1999048522A1 (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001024781A2 (en) * | 1999-10-07 | 2001-04-12 | Novaneuron Inc. | Gene necessary for striatal function, uses thereof, and compounds for modulating same |
| EP1334718A4 (en) * | 2000-10-26 | 2007-07-18 | Senju Pharma Co | DRUG COMPOSITION CONTAINING DIPEPTIDYL ALDEHYDE COMPOUND |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2098609A1 (en) * | 1990-12-28 | 1992-06-29 | Raymond T. Bartus | Use of calpain inhibitors in the inhibition and treatment of neurodegeneration |
| ATE230275T1 (de) * | 1995-10-25 | 2003-01-15 | Senju Pharma Co | Angiogense-inhibitor |
-
1999
- 1999-03-17 AU AU28526/99A patent/AU2852699A/en not_active Abandoned
- 1999-03-17 PL PL99342970A patent/PL342970A1/xx not_active Application Discontinuation
- 1999-03-17 MX MXPA00009188A patent/MXPA00009188A/es unknown
- 1999-03-17 WO PCT/JP1999/001335 patent/WO1999048522A1/en active IP Right Grant
- 1999-03-17 ES ES99909212T patent/ES2224613T3/es not_active Expired - Lifetime
- 1999-03-17 EP EP99909212A patent/EP1064021B1/en not_active Expired - Lifetime
- 1999-03-17 HU HU0101428A patent/HUP0101428A2/hu unknown
- 1999-03-17 US US09/646,529 patent/US6342531B1/en not_active Expired - Fee Related
- 1999-03-17 BR BR9908948-3A patent/BR9908948A/pt not_active Application Discontinuation
- 1999-03-17 MY MYPI99000998A patent/MY133063A/en unknown
- 1999-03-17 JP JP2000537569A patent/JP2002507579A/ja not_active Ceased
- 1999-03-17 KR KR1020007010291A patent/KR20010041967A/ko not_active Application Discontinuation
- 1999-03-17 CA CA002324566A patent/CA2324566A1/en not_active Abandoned
- 1999-03-17 CN CN99806167A patent/CN1301173A/zh active Pending
- 1999-03-17 ID IDW20002104A patent/ID27507A/id unknown
- 1999-03-17 DE DE69919995T patent/DE69919995T2/de not_active Expired - Lifetime
- 1999-03-17 AT AT99909212T patent/ATE275420T1/de not_active IP Right Cessation
- 1999-03-19 AR ARP990101215A patent/AR018784A1/es unknown
-
2000
- 2000-09-19 NO NO20004679A patent/NO20004679L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20004679D0 (no) | 2000-09-19 |
| WO1999048522A1 (en) | 1999-09-30 |
| MY133063A (en) | 2007-10-31 |
| PL342970A1 (en) | 2001-07-16 |
| DE69919995T2 (de) | 2005-09-22 |
| CN1301173A (zh) | 2001-06-27 |
| AR018784A1 (es) | 2001-12-12 |
| NO20004679L (no) | 2000-10-26 |
| CA2324566A1 (en) | 1999-09-30 |
| MXPA00009188A (es) | 2002-04-24 |
| KR20010041967A (ko) | 2001-05-25 |
| US6342531B1 (en) | 2002-01-29 |
| HUP0101428A2 (hu) | 2001-09-28 |
| EP1064021A1 (en) | 2001-01-03 |
| ES2224613T3 (es) | 2005-03-01 |
| ID27507A (id) | 2001-04-12 |
| AU2852699A (en) | 1999-10-18 |
| JP2002507579A (ja) | 2002-03-12 |
| DE69919995D1 (de) | 2004-10-14 |
| ATE275420T1 (de) | 2004-09-15 |
| EP1064021B1 (en) | 2004-09-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |