CA2295176A1 - Dispositifs d'administration de medicaments et methodes pour traiter des infections virales ou microbiennes ou le syndrome de deperissement - Google Patents

Dispositifs d'administration de medicaments et methodes pour traiter des infections virales ou microbiennes ou le syndrome de deperissement Download PDF

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Publication number
CA2295176A1
CA2295176A1 CA002295176A CA2295176A CA2295176A1 CA 2295176 A1 CA2295176 A1 CA 2295176A1 CA 002295176 A CA002295176 A CA 002295176A CA 2295176 A CA2295176 A CA 2295176A CA 2295176 A1 CA2295176 A1 CA 2295176A1
Authority
CA
Canada
Prior art keywords
dmf
therapeutic composition
alkyl groups
drug delivery
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002295176A
Other languages
English (en)
Inventor
Michelle Olga Patricia Giesteira Visser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIRODENE PHARMACEUTICAL HOLDINGS Pty Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/874,425 external-priority patent/US5935597A/en
Application filed by Individual filed Critical Individual
Publication of CA2295176A1 publication Critical patent/CA2295176A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Medical Informatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

On décrit de nouveaux dispositifs d'administration de médicaments, ainsi que des méthodes et des compositions thérapeutiques permettant de traiter chez l'animal ou l'homme des infections virales ou microbiennes ou le syndrome de dépérissement. Selon l'invention, un composé polaire (diméthylformamide ou diméthylsulfoxyde, par exemple) est administré, de préférence par voie transdermique, à un patient nécessitant un traitement. L'invention concerne en outre un vaccin préparé à partir d'anticorps recueillis chez un patient traité par la méthode de l'invention pour une infection virale.
CA002295176A 1997-06-13 1998-06-09 Dispositifs d'administration de medicaments et methodes pour traiter des infections virales ou microbiennes ou le syndrome de deperissement Abandoned CA2295176A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/874,425 1997-06-13
US08/874,425 US5935597A (en) 1995-12-15 1997-06-13 Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes
PCT/US1998/011956 WO1998056325A1 (fr) 1997-06-13 1998-06-09 Dispositifs d'administration de medicaments et methodes pour traiter des infections virales ou microbiennes ou le syndrome de deperissement

Publications (1)

Publication Number Publication Date
CA2295176A1 true CA2295176A1 (fr) 1998-12-17

Family

ID=25363728

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002295176A Abandoned CA2295176A1 (fr) 1997-06-13 1998-06-09 Dispositifs d'administration de medicaments et methodes pour traiter des infections virales ou microbiennes ou le syndrome de deperissement

Country Status (34)

Country Link
EP (1) EP1011567A4 (fr)
JP (1) JP4531141B2 (fr)
KR (1) KR20010013709A (fr)
CN (1) CN1260703A (fr)
AP (1) AP1629A (fr)
AR (1) AR012970A1 (fr)
AU (1) AU7831598A (fr)
BG (1) BG103997A (fr)
BR (1) BR9810095A (fr)
CA (1) CA2295176A1 (fr)
CZ (1) CZ298510B6 (fr)
EA (1) EA200000011A1 (fr)
EE (1) EE9900562A (fr)
ES (1) ES2161187B1 (fr)
FI (1) FI19992648A (fr)
GB (1) GB2341319B (fr)
HU (1) HUP0003034A2 (fr)
ID (1) ID23516A (fr)
IL (2) IL133396A0 (fr)
IS (1) IS5289A (fr)
LT (1) LT4714B (fr)
LV (1) LV12490B (fr)
NO (1) NO996117L (fr)
NZ (1) NZ501669A (fr)
OA (1) OA11307A (fr)
PL (1) PL196256B1 (fr)
RO (1) RO121252B1 (fr)
SI (1) SI20191A (fr)
SK (1) SK172299A3 (fr)
TN (1) TNSN98086A1 (fr)
TR (1) TR200000540T2 (fr)
WO (1) WO1998056325A1 (fr)
YU (1) YU66099A (fr)
ZA (1) ZA984649B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070212402A1 (en) * 2003-12-05 2007-09-13 Rooven Qainton V Patch

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US5534260A (en) * 1989-02-23 1996-07-09 University Of Utah Percutaneous drug delivery system
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
WO1993016992A1 (fr) * 1992-02-20 1993-09-02 Merrell Dow Pharmaceuticals Inc. Derives d'acide sulfonique utilises dans le traitement de maladies virales
SI9620126A (sl) * 1995-12-15 1999-10-31 Cryopreservation Technologies Cc (Za/Za) Spojina za kriogensko ohranjanje organov in zdravljenje virusnih ter bakterijskih infekcij

Also Published As

Publication number Publication date
HUP0003034A2 (hu) 2000-12-28
YU66099A (sh) 2002-10-18
GB2341319B (en) 2002-02-27
KR20010013709A (ko) 2001-02-26
LT99148A (en) 2000-07-25
PL196256B1 (pl) 2007-12-31
LT4714B (lt) 2000-10-25
CN1260703A (zh) 2000-07-19
ES2161187A1 (es) 2001-11-16
WO1998056325A1 (fr) 1998-12-17
PL338439A1 (en) 2000-11-06
IL133396A0 (en) 2001-04-30
TR200000540T2 (tr) 2000-09-21
IS5289A (is) 1999-12-08
CZ9904473A3 (cs) 2001-03-14
NZ501669A (en) 2001-09-28
NO996117D0 (no) 1999-12-10
IL133396A (en) 2006-10-05
AP9901708A0 (en) 1999-12-31
ZA984649B (en) 1999-12-17
TNSN98086A1 (fr) 2005-03-15
OA11307A (en) 2003-10-24
RO121252B1 (ro) 2007-02-28
EA200000011A1 (ru) 2000-08-28
NO996117L (no) 2000-02-11
AR012970A1 (es) 2000-11-22
JP4531141B2 (ja) 2010-08-25
ES2161187B1 (es) 2003-08-16
SI20191A (sl) 2000-10-31
GB9929189D0 (en) 2000-02-02
EE9900562A (et) 2000-06-15
AP1629A (en) 2006-07-11
EP1011567A1 (fr) 2000-06-28
LV12490B (en) 2000-12-20
EP1011567A4 (fr) 2000-06-28
AU7831598A (en) 1998-12-30
JP2002511862A (ja) 2002-04-16
BG103997A (en) 2001-07-31
CZ298510B6 (cs) 2007-10-24
SK172299A3 (en) 2000-09-12
GB2341319A (en) 2000-03-15
FI19992648A (fi) 2000-02-03
LV12490A (en) 2000-06-20
ID23516A (id) 2000-04-27
BR9810095A (pt) 2001-11-13

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued