BG103997A - Drug delivery device and methods for the treatment of viral and microbial infections and wasting syndromes - Google Patents

Drug delivery device and methods for the treatment of viral and microbial infections and wasting syndromes

Info

Publication number
BG103997A
BG103997A BG103997A BG10399799A BG103997A BG 103997 A BG103997 A BG 103997A BG 103997 A BG103997 A BG 103997A BG 10399799 A BG10399799 A BG 10399799A BG 103997 A BG103997 A BG 103997A
Authority
BG
Bulgaria
Prior art keywords
viral
treatment
methods
drug delivery
microbial infections
Prior art date
Application number
BG103997A
Other languages
Bulgarian (bg)
Inventor
Michelle Olga VISSER
Original Assignee
Virodene Pharmaceutical Holdings/Proprietary/Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/874,425 external-priority patent/US5935597A/en
Application filed by Virodene Pharmaceutical Holdings/Proprietary/Limited filed Critical Virodene Pharmaceutical Holdings/Proprietary/Limited
Publication of BG103997A publication Critical patent/BG103997A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel drug delivery devices, methods and therapeutic compositions are described for treating viral and microbial infections and wasting syndromes in an animal, including a human patient. According to the invention, a polar compound such as dimethylformamide or dimetyhylsulfoxide is administered to a patient in need of treatment, preferably by transdermal route. The invention further provides a vaccine prepared from antibodies harvested from the body of a patient treated by the method of the invention for a viral infection. 26 claims, 4 figures
BG103997A 1997-06-13 1999-12-13 Drug delivery device and methods for the treatment of viral and microbial infections and wasting syndromes BG103997A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/874,425 US5935597A (en) 1995-12-15 1997-06-13 Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes
PCT/US1998/011956 WO1998056325A1 (en) 1997-06-13 1998-06-09 Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes

Publications (1)

Publication Number Publication Date
BG103997A true BG103997A (en) 2001-07-31

Family

ID=25363728

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103997A BG103997A (en) 1997-06-13 1999-12-13 Drug delivery device and methods for the treatment of viral and microbial infections and wasting syndromes

Country Status (34)

Country Link
EP (1) EP1011567A1 (en)
JP (1) JP4531141B2 (en)
KR (1) KR20010013709A (en)
CN (1) CN1260703A (en)
AP (1) AP1629A (en)
AR (1) AR012970A1 (en)
AU (1) AU7831598A (en)
BG (1) BG103997A (en)
BR (1) BR9810095A (en)
CA (1) CA2295176A1 (en)
CZ (1) CZ298510B6 (en)
EA (1) EA200000011A1 (en)
EE (1) EE9900562A (en)
ES (1) ES2161187B1 (en)
FI (1) FI19992648A (en)
GB (1) GB2341319B (en)
HU (1) HUP0003034A2 (en)
ID (1) ID23516A (en)
IL (2) IL133396A0 (en)
IS (1) IS5289A (en)
LT (1) LT4714B (en)
LV (1) LV12490B (en)
NO (1) NO996117L (en)
NZ (1) NZ501669A (en)
OA (1) OA11307A (en)
PL (1) PL196256B1 (en)
RO (1) RO121252B1 (en)
SI (1) SI20191A (en)
SK (1) SK172299A3 (en)
TN (1) TNSN98086A1 (en)
TR (1) TR200000540T2 (en)
WO (1) WO1998056325A1 (en)
YU (1) YU66099A (en)
ZA (1) ZA984649B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1699430A1 (en) * 2003-12-05 2006-09-13 Namibia Medical Investments (PTY) Limited Patch

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US5534260A (en) * 1989-02-23 1996-07-09 University Of Utah Percutaneous drug delivery system
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
WO1993016992A1 (en) * 1992-02-20 1993-09-02 Merrell Dow Pharmaceuticals Inc. Sulfonic acid derivatives in the treatment of viral diseases
PL327199A1 (en) * 1995-12-15 1998-11-23 Cryopreservation Tech Cc Composition for cryopreservation of body organs and for treating viral and bacterial infections

Also Published As

Publication number Publication date
CN1260703A (en) 2000-07-19
EA200000011A1 (en) 2000-08-28
ES2161187B1 (en) 2003-08-16
EP1011567A4 (en) 2000-06-28
KR20010013709A (en) 2001-02-26
JP4531141B2 (en) 2010-08-25
BR9810095A (en) 2001-11-13
AP1629A (en) 2006-07-11
LT99148A (en) 2000-07-25
PL196256B1 (en) 2007-12-31
AR012970A1 (en) 2000-11-22
NO996117D0 (en) 1999-12-10
LT4714B (en) 2000-10-25
NZ501669A (en) 2001-09-28
ID23516A (en) 2000-04-27
IL133396A (en) 2006-10-05
PL338439A1 (en) 2000-11-06
YU66099A (en) 2002-10-18
FI19992648A (en) 2000-02-03
HUP0003034A2 (en) 2000-12-28
CA2295176A1 (en) 1998-12-17
LV12490B (en) 2000-12-20
AU7831598A (en) 1998-12-30
IS5289A (en) 1999-12-08
GB2341319A (en) 2000-03-15
SI20191A (en) 2000-10-31
EP1011567A1 (en) 2000-06-28
TR200000540T2 (en) 2000-09-21
TNSN98086A1 (en) 2005-03-15
AP9901708A0 (en) 1999-12-31
LV12490A (en) 2000-06-20
ES2161187A1 (en) 2001-11-16
JP2002511862A (en) 2002-04-16
WO1998056325A1 (en) 1998-12-17
OA11307A (en) 2003-10-24
RO121252B1 (en) 2007-02-28
CZ298510B6 (en) 2007-10-24
NO996117L (en) 2000-02-11
CZ9904473A3 (en) 2001-03-14
ZA984649B (en) 1999-12-17
SK172299A3 (en) 2000-09-12
IL133396A0 (en) 2001-04-30
EE9900562A (en) 2000-06-15
GB9929189D0 (en) 2000-02-02
GB2341319B (en) 2002-02-27

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