HUP0003034A2 - Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes - Google Patents
Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromesInfo
- Publication number
- HUP0003034A2 HUP0003034A2 HU0003034A HUP0003034A HUP0003034A2 HU P0003034 A2 HUP0003034 A2 HU P0003034A2 HU 0003034 A HU0003034 A HU 0003034A HU P0003034 A HUP0003034 A HU P0003034A HU P0003034 A2 HUP0003034 A2 HU P0003034A2
- Authority
- HU
- Hungary
- Prior art keywords
- treatment
- viral
- methods
- drug delivery
- delivery devices
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 238000012377 drug delivery Methods 0.000 title abstract 2
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 230000000813 microbial effect Effects 0.000 title abstract 2
- 230000003612 virological effect Effects 0.000 title abstract 2
- 208000010399 Wasting Syndrome Diseases 0.000 title 1
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 208000036142 Viral infection Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000006866 deterioration Effects 0.000 abstract 1
- 239000002547 new drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
- A61K31/10—Sulfides; Sulfoxides; Sulfones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/164—Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Medical Informatics (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
A találmány új gyógyszeradagoló eszközöket, eljárásokat és gyógyászatikészítményeket ismertet vírusos és mikrobás fertőzések, valamintleromlásitünet-csoportok kezelésére emberen vagy állaton. A találmányértelmében valamilyen poláris vegyületet, elsősorban például dimetil-formamidot vagy dimetil-szulfoxidot adagolnak egy ilyen kezelésreszoruló betegnek, előnyösen transzdermális úton. A találmány továbbáolyan vakcinára is vonatkozik, amelyet vírusfertőzés ellen a találmányszerinti módszerrel kezelt beteg szervezetéből gyűjtött antitestekbőlállítanak elő. ÓThe invention describes new drug delivery devices, methods and pharmaceutical compositions for the treatment of viral and microbial infections and groups of deterioration symptoms in humans or animals. According to the invention, a polar compound, primarily for example dimethylformamide or dimethylsulfoxide, is administered to a patient in need of such treatment, preferably by transdermal route. The invention also relates to a vaccine that is produced against viral infection from antibodies collected from the body of a patient treated with the method according to the invention. HE
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/874,425 US5935597A (en) | 1995-12-15 | 1997-06-13 | Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUP0003034A2 true HUP0003034A2 (en) | 2000-12-28 |
Family
ID=25363728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0003034A HUP0003034A2 (en) | 1997-06-13 | 1998-06-09 | Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes |
Country Status (34)
| Country | Link |
|---|---|
| EP (1) | EP1011567A4 (en) |
| JP (1) | JP4531141B2 (en) |
| KR (1) | KR20010013709A (en) |
| CN (1) | CN1260703A (en) |
| AP (1) | AP1629A (en) |
| AR (1) | AR012970A1 (en) |
| AU (1) | AU7831598A (en) |
| BG (1) | BG103997A (en) |
| BR (1) | BR9810095A (en) |
| CA (1) | CA2295176A1 (en) |
| CZ (1) | CZ298510B6 (en) |
| EA (1) | EA200000011A1 (en) |
| EE (1) | EE9900562A (en) |
| ES (1) | ES2161187B1 (en) |
| FI (1) | FI19992648A (en) |
| GB (1) | GB2341319B (en) |
| HU (1) | HUP0003034A2 (en) |
| ID (1) | ID23516A (en) |
| IL (2) | IL133396A0 (en) |
| IS (1) | IS5289A (en) |
| LT (1) | LT4714B (en) |
| LV (1) | LV12490B (en) |
| NO (1) | NO996117L (en) |
| NZ (1) | NZ501669A (en) |
| OA (1) | OA11307A (en) |
| PL (1) | PL196256B1 (en) |
| RO (1) | RO121252B1 (en) |
| SI (1) | SI20191A (en) |
| SK (1) | SK172299A3 (en) |
| TN (1) | TNSN98086A1 (en) |
| TR (1) | TR200000540T2 (en) |
| WO (1) | WO1998056325A1 (en) |
| YU (1) | YU66099A (en) |
| ZA (1) | ZA984649B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20070212402A1 (en) * | 2003-12-05 | 2007-09-13 | Rooven Qainton V | Patch |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE60941B1 (en) * | 1986-07-10 | 1994-09-07 | Elan Transdermal Ltd | Transdermal drug delivery device |
| US4855294A (en) * | 1988-09-06 | 1989-08-08 | Theratech, Inc. | Method for reducing skin irritation associated with drug/penetration enhancer compositions |
| US5534260A (en) * | 1989-02-23 | 1996-07-09 | University Of Utah | Percutaneous drug delivery system |
| US5028435A (en) * | 1989-05-22 | 1991-07-02 | Advanced Polymer Systems, Inc. | System and method for transdermal drug delivery |
| US5624912A (en) * | 1991-08-21 | 1997-04-29 | Burcoglu; Arsinur | Method of treating HIV infection and related secondary infections with defibrotide |
| WO1993016992A1 (en) * | 1992-02-20 | 1993-09-02 | Merrell Dow Pharmaceuticals Inc. | Sulfonic acid derivatives in the treatment of viral diseases |
| SI9620126A (en) * | 1995-12-15 | 1999-10-31 | Cryopreservation Technologies Cc (Za/Za) | Composition for organ cryopreservation and treatment of viral and bacterial infections |
-
1998
- 1998-05-29 ZA ZA9804649A patent/ZA984649B/en unknown
- 1998-06-09 ES ES009950072A patent/ES2161187B1/en not_active Expired - Lifetime
- 1998-06-09 CZ CZ0447399A patent/CZ298510B6/en not_active IP Right Cessation
- 1998-06-09 AP APAP/P/1999/001708A patent/AP1629A/en active
- 1998-06-09 ID IDW20000042A patent/ID23516A/en unknown
- 1998-06-09 HU HU0003034A patent/HUP0003034A2/en unknown
- 1998-06-09 IL IL13339698A patent/IL133396A0/en active IP Right Grant
- 1998-06-09 EA EA200000011A patent/EA200000011A1/en unknown
- 1998-06-09 CA CA002295176A patent/CA2295176A1/en not_active Abandoned
- 1998-06-09 AU AU78315/98A patent/AU7831598A/en not_active Abandoned
- 1998-06-09 NZ NZ501669A patent/NZ501669A/en unknown
- 1998-06-09 EE EEP199900562A patent/EE9900562A/en unknown
- 1998-06-09 GB GB9929189A patent/GB2341319B/en not_active Expired - Fee Related
- 1998-06-09 SI SI9820040A patent/SI20191A/en unknown
- 1998-06-09 YU YU66099A patent/YU66099A/en unknown
- 1998-06-09 JP JP50311899A patent/JP4531141B2/en not_active Expired - Fee Related
- 1998-06-09 WO PCT/US1998/011956 patent/WO1998056325A1/en active IP Right Grant
- 1998-06-09 CN CN98806085A patent/CN1260703A/en active Pending
- 1998-06-09 PL PL338439A patent/PL196256B1/en unknown
- 1998-06-09 BR BR9810095-5A patent/BR9810095A/en not_active Application Discontinuation
- 1998-06-09 KR KR1019997011724A patent/KR20010013709A/en not_active Application Discontinuation
- 1998-06-09 EP EP98926488A patent/EP1011567A4/en not_active Withdrawn
- 1998-06-09 SK SK1722-99A patent/SK172299A3/en unknown
- 1998-06-09 RO RO99-01313A patent/RO121252B1/en unknown
- 1998-06-09 TR TR2000/00540T patent/TR200000540T2/en unknown
- 1998-06-11 AR ARP980102783A patent/AR012970A1/en not_active Application Discontinuation
- 1998-06-12 TN TNTNSN98086A patent/TNSN98086A1/en unknown
-
1999
- 1999-12-08 IS IS5289A patent/IS5289A/en unknown
- 1999-12-09 FI FI992648A patent/FI19992648A/en unknown
- 1999-12-09 IL IL133396A patent/IL133396A/en not_active IP Right Cessation
- 1999-12-10 NO NO996117A patent/NO996117L/en not_active Application Discontinuation
- 1999-12-10 OA OA9900279A patent/OA11307A/en unknown
- 1999-12-13 BG BG103997A patent/BG103997A/en unknown
- 1999-12-20 LT LT99-148A patent/LT4714B/en not_active IP Right Cessation
-
2000
- 2000-02-02 LV LVP-99-182A patent/LV12490B/en unknown
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