ES2161187B1 - DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES. - Google Patents

DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES.

Info

Publication number
ES2161187B1
ES2161187B1 ES009950072A ES9950072A ES2161187B1 ES 2161187 B1 ES2161187 B1 ES 2161187B1 ES 009950072 A ES009950072 A ES 009950072A ES 9950072 A ES9950072 A ES 9950072A ES 2161187 B1 ES2161187 B1 ES 2161187B1
Authority
ES
Spain
Prior art keywords
syndromes
treatment
viral
methods
extenuation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES009950072A
Other languages
Spanish (es)
Other versions
ES2161187A1 (en
Inventor
Michelle Olga Patricia Visser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VIRODENE PHARMACEUTICAL HOLDIN
Original Assignee
VIRODENE PHARMACEUTICAL HOLDIN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/874,425 external-priority patent/US5935597A/en
Application filed by VIRODENE PHARMACEUTICAL HOLDIN filed Critical VIRODENE PHARMACEUTICAL HOLDIN
Publication of ES2161187A1 publication Critical patent/ES2161187A1/en
Application granted granted Critical
Publication of ES2161187B1 publication Critical patent/ES2161187B1/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/095Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10Sulfides; Sulfoxides; Sulfones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/164Amides, e.g. hydroxamic acids of a carboxylic acid with an aminoalcohol, e.g. ceramides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Abstract

Se describen nuevos dispositivos para el suministro de fármacos, métodos y composiciones terapéuticas para tratar infecciones víricas y microbianas síndromes de extenuación en un animal, incluyendo un paciente humano. De acuerdo con la invención, un compuesto polar tal como dimetilformamida o dimetilsulfóxido se administra a un paciente necesitado de tratamiento, preferentemente por una transdérmica. La invención proporciona además una vacuna preparada a partir de anticuerpos recogidos del cuerpo de un paciente tratado con el método de la invención vírica.New devices for the delivery of drugs, methods and therapeutic compositions for treating viral infections and microbial exhaustion syndromes in an animal, including a human patient, are described. According to the invention, a polar compound such as dimethylformamide or dimethylsulfoxide is administered to a patient in need of treatment, preferably by a transdermal. The invention further provides a vaccine prepared from antibodies collected from the body of a patient treated with the method of the viral invention.

ES009950072A 1997-06-13 1998-06-09 DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES. Expired - Lifetime ES2161187B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/874,425 US5935597A (en) 1995-12-15 1997-06-13 Drug delivery devices and methods for treatment of viral and microbial infections and wasting syndromes

Publications (2)

Publication Number Publication Date
ES2161187A1 ES2161187A1 (en) 2001-11-16
ES2161187B1 true ES2161187B1 (en) 2003-08-16

Family

ID=25363728

Family Applications (1)

Application Number Title Priority Date Filing Date
ES009950072A Expired - Lifetime ES2161187B1 (en) 1997-06-13 1998-06-09 DEVICES FOR SUPPLY OF PHARMACOS AND METHODS FOR THE TREATMENT OF VIRAL AND MICROBIAL INFECTIONS AND EXTENUATION SYNDROMES.

Country Status (34)

Country Link
EP (1) EP1011567A1 (en)
JP (1) JP4531141B2 (en)
KR (1) KR20010013709A (en)
CN (1) CN1260703A (en)
AP (1) AP1629A (en)
AR (1) AR012970A1 (en)
AU (1) AU7831598A (en)
BG (1) BG103997A (en)
BR (1) BR9810095A (en)
CA (1) CA2295176A1 (en)
CZ (1) CZ298510B6 (en)
EA (1) EA200000011A1 (en)
EE (1) EE9900562A (en)
ES (1) ES2161187B1 (en)
FI (1) FI19992648A (en)
GB (1) GB2341319B (en)
HU (1) HUP0003034A2 (en)
ID (1) ID23516A (en)
IL (2) IL133396A0 (en)
IS (1) IS5289A (en)
LT (1) LT4714B (en)
LV (1) LV12490B (en)
NO (1) NO996117L (en)
NZ (1) NZ501669A (en)
OA (1) OA11307A (en)
PL (1) PL196256B1 (en)
RO (1) RO121252B1 (en)
SI (1) SI20191A (en)
SK (1) SK172299A3 (en)
TN (1) TNSN98086A1 (en)
TR (1) TR200000540T2 (en)
WO (1) WO1998056325A1 (en)
YU (1) YU66099A (en)
ZA (1) ZA984649B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP2006003648A0 (en) * 2003-12-05 2006-06-30 Namibia Medical Invest Pty Ltd Patch

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
US4855294A (en) * 1988-09-06 1989-08-08 Theratech, Inc. Method for reducing skin irritation associated with drug/penetration enhancer compositions
US5534260A (en) * 1989-02-23 1996-07-09 University Of Utah Percutaneous drug delivery system
US5028435A (en) * 1989-05-22 1991-07-02 Advanced Polymer Systems, Inc. System and method for transdermal drug delivery
US5624912A (en) * 1991-08-21 1997-04-29 Burcoglu; Arsinur Method of treating HIV infection and related secondary infections with defibrotide
ATE165345T1 (en) * 1992-02-20 1998-05-15 Merrell Pharma Inc SULFONIC ACID DERIVATIVES FOR THE TREATMENT OF VIRUS DISEASES
AU724026B2 (en) * 1995-12-15 2000-09-07 Virodene Pharmaceutical Holdings (Pty) Ltd. Composition for organ cryopreservation and treatment of viral and bacterial infections

Also Published As

Publication number Publication date
TR200000540T2 (en) 2000-09-21
LV12490B (en) 2000-12-20
CZ298510B6 (en) 2007-10-24
OA11307A (en) 2003-10-24
RO121252B1 (en) 2007-02-28
TNSN98086A1 (en) 2005-03-15
AR012970A1 (en) 2000-11-22
AP9901708A0 (en) 1999-12-31
HUP0003034A2 (en) 2000-12-28
EP1011567A4 (en) 2000-06-28
BR9810095A (en) 2001-11-13
KR20010013709A (en) 2001-02-26
CZ9904473A3 (en) 2001-03-14
EP1011567A1 (en) 2000-06-28
CN1260703A (en) 2000-07-19
GB9929189D0 (en) 2000-02-02
IS5289A (en) 1999-12-08
WO1998056325A1 (en) 1998-12-17
BG103997A (en) 2001-07-31
ID23516A (en) 2000-04-27
EA200000011A1 (en) 2000-08-28
CA2295176A1 (en) 1998-12-17
AU7831598A (en) 1998-12-30
PL338439A1 (en) 2000-11-06
AP1629A (en) 2006-07-11
GB2341319B (en) 2002-02-27
JP4531141B2 (en) 2010-08-25
IL133396A0 (en) 2001-04-30
LV12490A (en) 2000-06-20
SI20191A (en) 2000-10-31
ES2161187A1 (en) 2001-11-16
YU66099A (en) 2002-10-18
JP2002511862A (en) 2002-04-16
NO996117D0 (en) 1999-12-10
LT4714B (en) 2000-10-25
GB2341319A (en) 2000-03-15
SK172299A3 (en) 2000-09-12
EE9900562A (en) 2000-06-15
FI19992648A (en) 2000-02-03
ZA984649B (en) 1999-12-17
NZ501669A (en) 2001-09-28
IL133396A (en) 2006-10-05
LT99148A (en) 2000-07-25
PL196256B1 (en) 2007-12-31
NO996117L (en) 2000-02-11

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