CA2286733C - Reverse-turn mimetics and methods relating thereto - Google Patents
Reverse-turn mimetics and methods relating thereto Download PDFInfo
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- CA2286733C CA2286733C CA002286733A CA2286733A CA2286733C CA 2286733 C CA2286733 C CA 2286733C CA 002286733 A CA002286733 A CA 002286733A CA 2286733 A CA2286733 A CA 2286733A CA 2286733 C CA2286733 C CA 2286733C
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- compound
- turn
- amino acid
- mimetics
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/846,432 | 1997-04-30 | ||
| US08/846,432 US6013458A (en) | 1995-10-27 | 1997-04-30 | Reverse-turn mimetics and methods relating thereto |
| PCT/US1998/008542 WO1998049168A1 (en) | 1997-04-30 | 1998-04-28 | Reverse-turn mimetics and methods relating thereto |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2286733A1 CA2286733A1 (en) | 1998-11-05 |
| CA2286733C true CA2286733C (en) | 2004-07-20 |
Family
ID=25297917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002286733A Expired - Fee Related CA2286733C (en) | 1997-04-30 | 1998-04-28 | Reverse-turn mimetics and methods relating thereto |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6013458A (enExample) |
| EP (1) | EP0980373A1 (enExample) |
| JP (1) | JP2001526651A (enExample) |
| KR (1) | KR20010020416A (enExample) |
| AU (1) | AU743777B2 (enExample) |
| CA (1) | CA2286733C (enExample) |
| WO (1) | WO1998049168A1 (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6184223B1 (en) * | 1995-10-27 | 2001-02-06 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
| AUPP254898A0 (en) * | 1998-03-24 | 1998-04-23 | University Of Queensland, The | Peptide turn mimetics |
| DE60020366T2 (de) * | 1999-06-14 | 2006-02-02 | Genentech Inc., San Francisco | Strukturiertes peptidgerüst zur ausstellung von drehung-bibliotheken auf phage |
| US20030166003A1 (en) * | 1999-06-14 | 2003-09-04 | Cochran Andrea G. | Structured peptide scaffold for displaying turn libraries on phage |
| US6294525B1 (en) * | 1999-09-01 | 2001-09-25 | Molecumetics Ltd. | Reverse-turn mimetics and methods relating thereto |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06505486A (ja) * | 1991-02-07 | 1994-06-23 | モレキュメティクス，リミティド | βターンおよびβバルジのコンフォメーション的に制限された模倣物およびそれらを含有するペプチド |
| JPH07509723A (ja) * | 1992-08-06 | 1995-10-26 | モレキュメティクス，リミティド | 反転型ターンの立体配座的に拘束されたミメティックスと前者を含有するペプチド |
| US5288514A (en) * | 1992-09-14 | 1994-02-22 | The Regents Of The University Of California | Solid phase and combinatorial synthesis of benzodiazepine compounds on a solid support |
| US5886186A (en) * | 1995-10-25 | 1999-03-23 | Versicor, Inc. | Synthesis of substituted N-heteroaromatic compounds and methods of use thereof |
-
1997
- 1997-04-30 US US08/846,432 patent/US6013458A/en not_active Expired - Lifetime
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1998
- 1998-04-28 EP EP98918829A patent/EP0980373A1/en not_active Withdrawn
- 1998-04-28 JP JP54729198A patent/JP2001526651A/ja active Pending
- 1998-04-28 KR KR1019997010040A patent/KR20010020416A/ko not_active Ceased
- 1998-04-28 WO PCT/US1998/008542 patent/WO1998049168A1/en not_active Ceased
- 1998-04-28 CA CA002286733A patent/CA2286733C/en not_active Expired - Fee Related
- 1998-04-28 AU AU71679/98A patent/AU743777B2/en not_active Ceased
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| WO1998049168A1 (en) | 1998-11-05 |
| CA2286733A1 (en) | 1998-11-05 |
| EP0980373A1 (en) | 2000-02-23 |
| JP2001526651A (ja) | 2001-12-18 |
| US6013458A (en) | 2000-01-11 |
| AU743777B2 (en) | 2002-02-07 |
| AU7167998A (en) | 1998-11-24 |
| KR20010020416A (ko) | 2001-03-15 |
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