CA2286484A1 - .beta.-amyloid peptide-binding proteins and polynucleotides encoding the same - Google Patents

.beta.-amyloid peptide-binding proteins and polynucleotides encoding the same Download PDF

Info

Publication number
CA2286484A1
CA2286484A1 CA002286484A CA2286484A CA2286484A1 CA 2286484 A1 CA2286484 A1 CA 2286484A1 CA 002286484 A CA002286484 A CA 002286484A CA 2286484 A CA2286484 A CA 2286484A CA 2286484 A1 CA2286484 A1 CA 2286484A1
Authority
CA
Canada
Prior art keywords
protein
amino acid
beta
polynucleotide
amyloid peptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002286484A
Other languages
English (en)
French (fr)
Inventor
Bradley Alton Ozenberger
Eileen Marie Kajkowski
Jack Steven Jacobsen
Jonathan Adam Bard
Stephen Glenn Walker
Heidi Sofia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2286484A1 publication Critical patent/CA2286484A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002286484A 1997-04-16 1998-04-14 .beta.-amyloid peptide-binding proteins and polynucleotides encoding the same Abandoned CA2286484A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16
US60/064,583 1997-04-16
PCT/US1998/007462 WO1998046636A2 (en) 1997-04-16 1998-04-14 β-AMYLOID PEPTIDE-BINDING PROTEINS AND POLYNUCLEOTIDES ENCODING THE SAME

Publications (1)

Publication Number Publication Date
CA2286484A1 true CA2286484A1 (en) 1998-10-22

Family

ID=22056941

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002286484A Abandoned CA2286484A1 (en) 1997-04-16 1998-04-14 .beta.-amyloid peptide-binding proteins and polynucleotides encoding the same

Country Status (18)

Country Link
EP (1) EP0975753A2 (zh)
JP (3) JP2001523093A (zh)
KR (1) KR20010006393A (zh)
CN (2) CN1690203A (zh)
AU (1) AU740445B2 (zh)
BR (1) BR9808562A (zh)
CA (1) CA2286484A1 (zh)
EA (1) EA004256B1 (zh)
EE (1) EE9900482A (zh)
GE (1) GEP20043386B (zh)
HU (1) HUP0003116A3 (zh)
ID (1) ID24914A (zh)
IL (3) IL132236A0 (zh)
NO (1) NO995062L (zh)
NZ (1) NZ500216A (zh)
SK (1) SK143299A3 (zh)
UA (1) UA72875C2 (zh)
WO (1) WO1998046636A2 (zh)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
US6787319B2 (en) 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
JP2002527064A (ja) * 1998-10-13 2002-08-27 アメリカン・ホーム・プロダクツ・コーポレイション ６−蛋白結合受容体様蛋白、それらによりコードされるポリヌクレオチド、ならびにそれらの使用方法
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
EP1226241A1 (en) * 1999-10-21 2002-07-31 Panorama Research, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
WO2012020124A1 (en) 2010-08-12 2012-02-16 Ac Immune S.A. Vaccine engineering
CN103189050B (zh) 2010-10-26 2017-09-29 Ac免疫有限公司 包含通过疏水部分修饰的肽的基于脂质体的构建体
CN102060912B (zh) * 2010-11-22 2012-11-14 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用
CN111320678B (zh) * 2020-03-09 2023-06-09 安亭生物有限责任公司 抗菌肽突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988003951A1 (en) * 1986-11-17 1988-06-02 California Biotechnology, Inc. Recombinant alzheimer's amyloid protein
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
NO995062L (no) 1999-12-14
WO1998046636A3 (en) 1999-01-28
KR20010006393A (ko) 2001-01-26
JP2001523093A (ja) 2001-11-20
HUP0003116A2 (hu) 2001-01-29
CN1690203A (zh) 2005-11-02
SK143299A3 (en) 2000-09-12
ID24914A (id) 2000-08-31
EE9900482A (zh) 2000-06-15
JP2008104465A (ja) 2008-05-08
UA72875C2 (uk) 2005-05-16
IL179047A0 (en) 2007-03-08
IL132236A (en) 2007-03-08
BR9808562A (pt) 2000-05-23
JP2008253275A (ja) 2008-10-23
HUP0003116A3 (en) 2003-03-28
AU7115698A (en) 1998-11-11
AU740445B2 (en) 2001-11-01
GEP20043386B (en) 2004-02-10
NO995062D0 (no) 1999-10-15
WO1998046636A2 (en) 1998-10-22
CN1268973A (zh) 2000-10-04
IL132236A0 (en) 2001-03-19
CN1196785C (zh) 2005-04-13
NZ500216A (en) 2001-06-29
EA004256B1 (ru) 2004-02-26
EP0975753A2 (en) 2000-02-02
EA199900941A1 (ru) 2000-06-26

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued