CA2285565A1 - Fibre adenovirale modifiee et adenovirus cibles - Google Patents
Fibre adenovirale modifiee et adenovirus cibles Download PDFInfo
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- CA2285565A1 CA2285565A1 CA002285565A CA2285565A CA2285565A1 CA 2285565 A1 CA2285565 A1 CA 2285565A1 CA 002285565 A CA002285565 A CA 002285565A CA 2285565 A CA2285565 A CA 2285565A CA 2285565 A1 CA2285565 A1 CA 2285565A1
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- adenovirus
- fiber
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C12N2810/851—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from growth factors; from growth regulators
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- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
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- Processing Of Solid Wastes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9703987A FR2761688A1 (fr) | 1997-04-02 | 1997-04-02 | Fibre adenovirale modifiee et adenovirus cibles |
| FR97/04747 | 1997-04-17 | ||
| FR9704747A FR2761689B1 (fr) | 1997-04-02 | 1997-04-17 | Fibre adenovirale modifiee et adenovirus cibles |
| FR97/03987 | 1997-04-17 | ||
| PCT/FR1998/000668 WO1998044121A1 (fr) | 1997-04-02 | 1998-04-02 | Fibre adenovirale modifiee et adenovirus cibles |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2285565A1 true CA2285565A1 (fr) | 1998-10-08 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002285565A Abandoned CA2285565A1 (fr) | 1997-04-02 | 1998-04-02 | Fibre adenovirale modifiee et adenovirus cibles |
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| US (2) | US6569677B1 (enExample) |
| EP (1) | EP0991763B1 (enExample) |
| JP (1) | JP2001522236A (enExample) |
| AT (1) | ATE305513T1 (enExample) |
| AU (1) | AU741728B2 (enExample) |
| CA (1) | CA2285565A1 (enExample) |
| DE (1) | DE69831741T2 (enExample) |
| DK (1) | DK0991763T3 (enExample) |
| ES (1) | ES2246533T3 (enExample) |
| FR (1) | FR2761689B1 (enExample) |
| WO (1) | WO1998044121A1 (enExample) |
Families Citing this family (50)
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| US7232899B2 (en) | 1996-09-25 | 2007-06-19 | The Scripps Research Institute | Adenovirus vectors, packaging cell lines, compositions, and methods for preparation and use |
| WO1999055365A1 (en) | 1998-04-30 | 1999-11-04 | Cornell Research Foundation, Inc. | Adenoviral vectors with tandem fiber proteins |
| CA2342396A1 (en) * | 1998-09-11 | 2000-03-23 | Genvec, Inc. | Alternatively targeted adenovirus |
| IL133032A (en) * | 1998-11-20 | 2007-06-03 | Introgene Bv | Adenoviral gene delivery vectors provided with a tissue tropism for smooth muscle cells and /or endothelial cells |
| EP1020529B1 (en) * | 1998-11-20 | 2005-06-01 | Crucell Holland B.V. | Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells |
| JP2000279178A (ja) * | 1999-02-24 | 2000-10-10 | Japan Found Cancer Res | ウイルスベクター |
| DE19932688B4 (de) * | 1999-07-13 | 2009-10-08 | Scil Proteins Gmbh | Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen |
| US7560527B1 (en) | 1999-11-25 | 2009-07-14 | Transgene S.A. | Modified adenovirus fibre and uses |
| AU6368901A (en) * | 2000-05-31 | 2001-12-11 | Univ Saskatchewan | Modified bovine adenovirus having altered tropism |
| CA2410981A1 (en) * | 2000-06-02 | 2001-12-06 | Novartis Ag | Adenovirus particles with mutagenized fiber proteins |
| CA2491805A1 (en) * | 2002-07-10 | 2004-01-22 | Transgene S.A. | Modified adenoviral fiber with ablated binding to cellular receptors |
| WO2005027711A2 (en) * | 2003-05-01 | 2005-03-31 | University Of Washington | Capsid-modified adenovirus vectors and methods of using the same |
| US7611868B2 (en) * | 2003-05-14 | 2009-11-03 | Instituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Recombinant modified adenovirus fiber protein |
| DE10324447A1 (de) | 2003-05-28 | 2004-12-30 | Scil Proteins Gmbh | Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin |
| GB0313132D0 (en) * | 2003-06-06 | 2003-07-09 | Ich Productions Ltd | Peptide ligands |
| WO2005030927A2 (en) * | 2003-09-23 | 2005-04-07 | Uab Research Foundation | Methods and compositions for in vivo inflammation monitoring |
| ES2871907T3 (es) * | 2004-01-23 | 2021-11-02 | Msd Italia Srl | Portadores de vacuna de adenovirus de chimpancé |
| DE102004049479A1 (de) | 2004-10-11 | 2006-04-13 | Scil Proteins Gmbh | Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie |
| US20070010016A1 (en) * | 2005-03-11 | 2007-01-11 | Mccelland Alan | Gene transfer with adenoviruses having modified fiber proteins |
| EP1893636A2 (en) * | 2005-06-17 | 2008-03-05 | Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. | Hepatitis c virus nucleic acid vaccine |
| WO2007094653A1 (en) * | 2006-02-13 | 2007-08-23 | Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg | Adenovirus particles having a chimeric adenovirus spike protein, use thereof and methods for producing such particles. |
| EP1925664A1 (en) * | 2006-11-15 | 2008-05-28 | Scil proteins GmbH | Artificial binding proteins based on a modified alpha helical region of ubiquitin |
| WO2009111738A2 (en) | 2008-03-06 | 2009-09-11 | Mayo Foundation For Medical Education And Research | Single cycle replicating adenovirus vectors |
| BR112012014194A2 (pt) | 2009-12-14 | 2017-01-10 | Scil Proteins Gmbh | um método para identificar proteínas ubiquitinas modificadas hetero-multiméricas com capacidade de ligação a ligandos |
| EP2721152B1 (en) | 2011-06-15 | 2019-03-27 | Navigo Proteins GmbH | Dimeric binding proteins based on modified ubiquitins |
| CA2903582C (en) | 2013-03-14 | 2021-06-08 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| JP6738340B2 (ja) | 2015-02-06 | 2020-08-12 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | 新規なｅｇｆｒ結合タンパク質 |
| ES2916101T3 (es) | 2015-07-16 | 2022-06-28 | Navigo Proteins Gmbh | Nuevas proteínas de unión a inmunoglobulina y su uso en la purificación por afinidad |
| JP2018520675A (ja) | 2015-07-20 | 2018-08-02 | ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ | ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法 |
| JP7015551B2 (ja) | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1994017832A1 (en) * | 1993-02-09 | 1994-08-18 | The Scripps Research Institute | Targeting and delivery of genes and antiviral agents into cells by the adenovirus penton |
| FR2705686B1 (fr) | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
| US5543328A (en) | 1993-08-13 | 1996-08-06 | Genetic Therapy, Inc. | Adenoviruses having modified fiber proteins |
| US5820868A (en) | 1993-12-09 | 1998-10-13 | Veterinary Infectious Disease Organization | Recombinant protein production in bovine adenovirus expression vector system |
| US6312699B1 (en) * | 1994-03-28 | 2001-11-06 | Uab Research Foundation | Ligands added to adenovirus fiber |
| US5846782A (en) * | 1995-11-28 | 1998-12-08 | Genvec, Inc. | Targeting adenovirus with use of constrained peptide motifs |
| CA2203809C (en) * | 1994-10-28 | 2008-06-03 | James M. Wilson | Recombinant adenovirus and methods of use thereof |
| FR2727689A1 (fr) | 1994-12-01 | 1996-06-07 | Transgene Sa | Nouveau procede de preparation d'un vecteur viral |
| US5770442A (en) * | 1995-02-21 | 1998-06-23 | Cornell Research Foundation, Inc. | Chimeric adenoviral fiber protein and methods of using same |
| IL124654A0 (en) * | 1995-11-28 | 1998-12-06 | Genvec Inc | Vectors and method for gene transfer to cells |
| WO2001016344A1 (fr) * | 1999-08-27 | 2001-03-08 | Transgene S.A. | Fibre adenovirale modifiee et utilisations |
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1997
- 1997-04-17 FR FR9704747A patent/FR2761689B1/fr not_active Expired - Fee Related
-
1998
- 1998-04-02 DK DK98917294T patent/DK0991763T3/da active
- 1998-04-02 US US09/402,401 patent/US6569677B1/en not_active Expired - Fee Related
- 1998-04-02 EP EP98917294A patent/EP0991763B1/fr not_active Expired - Lifetime
- 1998-04-02 AU AU70547/98A patent/AU741728B2/en not_active Ceased
- 1998-04-02 ES ES98917294T patent/ES2246533T3/es not_active Expired - Lifetime
- 1998-04-02 CA CA002285565A patent/CA2285565A1/fr not_active Abandoned
- 1998-04-02 AT AT98917294T patent/ATE305513T1/de not_active IP Right Cessation
- 1998-04-02 JP JP54126098A patent/JP2001522236A/ja not_active Ceased
- 1998-04-02 WO PCT/FR1998/000668 patent/WO1998044121A1/fr not_active Ceased
- 1998-04-02 DE DE69831741T patent/DE69831741T2/de not_active Expired - Fee Related
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2003
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Also Published As
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|---|---|
| DE69831741T2 (de) | 2006-07-06 |
| FR2761689A1 (fr) | 1998-10-09 |
| US7256036B2 (en) | 2007-08-14 |
| AU741728B2 (en) | 2001-12-06 |
| DE69831741D1 (de) | 2006-02-09 |
| ES2246533T3 (es) | 2006-02-16 |
| AU7054798A (en) | 1998-10-22 |
| US6569677B1 (en) | 2003-05-27 |
| WO1998044121A1 (fr) | 1998-10-08 |
| EP0991763A1 (fr) | 2000-04-12 |
| JP2001522236A (ja) | 2001-11-13 |
| FR2761689B1 (fr) | 1999-06-25 |
| DK0991763T3 (da) | 2006-02-20 |
| US20030175243A1 (en) | 2003-09-18 |
| ATE305513T1 (de) | 2005-10-15 |
| EP0991763B1 (fr) | 2005-09-28 |
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