CA2267066A1 - Vaccin meningocoque comportant la valence de souche bz83 - Google Patents

Vaccin meningocoque comportant la valence de souche bz83 Download PDF

Info

Publication number
CA2267066A1
CA2267066A1 CA002267066A CA2267066A CA2267066A1 CA 2267066 A1 CA2267066 A1 CA 2267066A1 CA 002267066 A CA002267066 A CA 002267066A CA 2267066 A CA2267066 A CA 2267066A CA 2267066 A1 CA2267066 A1 CA 2267066A1
Authority
CA
Canada
Prior art keywords
gly
ala
lys
ser
thr
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002267066A
Other languages
English (en)
Inventor
Marie-Jose Quentin-Millet
Bachra Rokbi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Pasteur SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2267066A1 publication Critical patent/CA2267066A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention a pour objet une composition pharmaceutique comprenant (i) la sous-unité de moindre poids moléculaire (TbpB) du récepteur de la transferrine humaine (RTH) d'une souche de Neisseria meningitidis possédant une séquence d'ADN codant pour TbpB, (a) qui contient 2 sites de restriction AvaII, 3 sites de restriction HincII, aucun site de restriction VspI et aucun site de restriction XhoI ou (b) à partir de laquelle il est possible de générer par PCR (polymérase chain reaction) à l'aide des amorces P3 de formule 5'-AAGACCAAGGCGGATACGGTTTTGC-3' et P4 de formule 5'-GAAGACGAGTCGGAAACAAAGGGATG-3', un polynucléotide de 765 à 775 nucléotides. Une telle souche est par exemple la souche BZ83 dont la séquence d'ADN codant pour TbpB est montrée dans le SEQ ID NO 1.
CA002267066A 1997-08-07 1998-08-03 Vaccin meningocoque comportant la valence de souche bz83 Abandoned CA2267066A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR97/10301 1997-08-07
FR9710301A FR2767060B1 (fr) 1997-08-07 1997-08-07 Vaccin meningocoque comportant la valence de souche bz83
PCT/FR1998/001730 WO1999007741A1 (fr) 1997-08-07 1998-08-03 Vaccin meningocoque comportant la valence de souche bz83

Publications (1)

Publication Number Publication Date
CA2267066A1 true CA2267066A1 (fr) 1999-02-18

Family

ID=9510254

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002267066A Abandoned CA2267066A1 (fr) 1997-08-07 1998-08-03 Vaccin meningocoque comportant la valence de souche bz83

Country Status (10)

Country Link
EP (1) EP0948534A1 (fr)
JP (1) JP2001503068A (fr)
CN (1) CN1241193A (fr)
AU (1) AU8987598A (fr)
CA (1) CA2267066A1 (fr)
FR (1) FR2767060B1 (fr)
HU (1) HUP0001451A3 (fr)
NO (1) NO991558L (fr)
NZ (1) NZ334992A (fr)
WO (1) WO1999007741A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10232029B2 (en) 2014-12-09 2019-03-19 Sanofi Pasteur Compositions comprising N. meningitidis proteins

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0107219D0 (en) * 2001-03-22 2001-05-16 Microbiological Res Authority Immunogenic commensal neisseria sequences
JP2016539950A (ja) * 2013-12-02 2016-12-22 ビー． シュライバーズ，アンソニー 細菌表面受容体タンパク質由来の免疫原性組成物およびワクチン

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5292869A (en) * 1989-04-27 1994-03-08 The Board Of Governors Of The University Method for isolating and purifying transferrin and lactoferrin receptor proteins from bacteria and the preparation of vaccines containing the same
FR2682041B1 (fr) * 1991-10-03 1994-01-14 Pasteur Merieux Serums Vaccins Vaccin contre les infections a neisseria meningitidis.
FR2692592B1 (fr) * 1992-06-19 1995-03-31 Pasteur Merieux Serums Vacc Fragments d'ADN codant pour les sous-unités du récepteur de la transferrine de Neisseria meningitidis et procédés les exprimant.
FR2720408B1 (fr) * 1994-05-31 1996-08-14 Pasteur Merieux Serums Vacc Fragments Tbp2 de Neisseria meningitidis.
FR2739624B1 (fr) * 1995-10-10 1997-12-05 Pasteur Merieux Serums Vacc Nouvelle sous-unite tbp2 de neisseria meningitidis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10232029B2 (en) 2014-12-09 2019-03-19 Sanofi Pasteur Compositions comprising N. meningitidis proteins

Also Published As

Publication number Publication date
NZ334992A (en) 2001-09-28
NO991558D0 (no) 1999-03-30
JP2001503068A (ja) 2001-03-06
HUP0001451A3 (en) 2001-09-28
EP0948534A1 (fr) 1999-10-13
NO991558L (no) 1999-03-30
WO1999007741A1 (fr) 1999-02-18
FR2767060A1 (fr) 1999-02-12
AU8987598A (en) 1999-03-01
FR2767060B1 (fr) 2000-02-11
CN1241193A (zh) 2000-01-12
HUP0001451A2 (hu) 2001-04-28

Similar Documents

Publication Publication Date Title
KR20070102447A (ko) 독성 유전자, 단백질, 및 그 용도
JP2001515359A (ja) 結核菌由来の核酸フラグメント及びポリペプチドフラグメント
US7723504B2 (en) Nontypeable Haemophilus influenzae virulence factors
WO1996012020A9 (fr) Recepteurs d'hemoglobine obtenus a partir de neisseriae
HUT77048A (hu) Neisseria-eredetű hemoglobin-receptorok
EP0749322A1 (fr) H. pilori n'exprimant pas une toxine vacuolisante et procedes associes
CA2207302A1 (fr) Sous-unite tbp2 de neisseria meningitidis
EP0793720A2 (fr) Recepteurs d'hemoglobine obtenus a partir de neisseriae
Simpson et al. Transposition of the endogenous insertion sequence element IS 1126 modulates gingipain expression in Porphyromonas gingivalis
CA2267066A1 (fr) Vaccin meningocoque comportant la valence de souche bz83
WO2000021989A9 (fr) Proteines dbp a et b liant la decorine et gene codant pour elles
US6617128B2 (en) Nucleic acid molecules encoding proteins which impart the adhesion of neisseria cells to human cells
AU684798B2 (en) Regulator of contact-mediated hemolysin
JP4503175B2 (ja) モラクセラ・カタラーリス（Ｍｏｒａｘｅｌｌａｃａｔａｒｒｈａｌｉｓ）由来の化合物
ES2253894T3 (es) Polinucleotidos y polipeptidos de moraxella catarrhalis.
JP4503177B2 (ja) モラクセラ・カタラーリス（Ｍｏｒａｘｅｌｌａｃａｔａｒｒｈａｌｉｓ）由来のＢＡＳＢ０２７タンパク質およびＢＡＳＢ０２７遺伝子、抗原、抗体、ならびに使用
WO1999057277A2 (fr) Proteines basb019 et genes issus de moxarella catarrhalis, antigenes, anticorps et utilisation de ces derniers
EP1082436A2 (fr) Nouveaux composes
KR20010085794A (ko) 모락셀라 카탈리스 ｂａｓｂ034 폴리펩티드 및 이들의용도
US20030170261A1 (en) Virulence genes, proteins, and their use
US6277382B1 (en) Hemoglobin receptors from neisseriae
CN100469871C (zh) 一种低热原葡激酶及其制备方法
Ren Studies on the Haemophilus influenzae hemoglobin/hemoglobin-haptoglobin binding proteins: Gene cloning, characterization, regulation and bacterial pathogenesis
ZA200007108B (en) BASB027 proteins and genes from moraxella catarrhalis, antigens, antibodies, and uses.

Legal Events

Date Code Title Description
FZDE Discontinued