CA2264552C - Method of using tetracycline compounds for inhibition of nitric oxide production - Google Patents
Method of using tetracycline compounds for inhibition of nitric oxide production Download PDFInfo
- Publication number
- CA2264552C CA2264552C CA002264552A CA2264552A CA2264552C CA 2264552 C CA2264552 C CA 2264552C CA 002264552 A CA002264552 A CA 002264552A CA 2264552 A CA2264552 A CA 2264552A CA 2264552 C CA2264552 C CA 2264552C
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- nitric oxide
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- tetracycline compound
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CA002670296A CA2670296A1 (en) | 1996-08-30 | 1997-08-21 | Method of using tetracycline compounds for inhibition of nitric oxide production |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/697,815 | 1996-08-30 | ||
| US08/697,815 US5789395A (en) | 1996-08-30 | 1996-08-30 | Method of using tetracycline compounds for inhibition of endogenous nitric oxide production |
| PCT/US1997/014723 WO1998008480A2 (en) | 1996-08-30 | 1997-08-21 | Method of using tetracycline compounds for inhibition of nitric oxide production |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002670296A Division CA2670296A1 (en) | 1996-08-30 | 1997-08-21 | Method of using tetracycline compounds for inhibition of nitric oxide production |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2264552A1 CA2264552A1 (en) | 1998-03-05 |
| CA2264552C true CA2264552C (en) | 2009-10-13 |
Family
ID=24802673
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002264552A Expired - Lifetime CA2264552C (en) | 1996-08-30 | 1997-08-21 | Method of using tetracycline compounds for inhibition of nitric oxide production |
| CA002670296A Abandoned CA2670296A1 (en) | 1996-08-30 | 1997-08-21 | Method of using tetracycline compounds for inhibition of nitric oxide production |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002670296A Abandoned CA2670296A1 (en) | 1996-08-30 | 1997-08-21 | Method of using tetracycline compounds for inhibition of nitric oxide production |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US5789395A (enExample) |
| EP (1) | EP0966525A4 (enExample) |
| JP (1) | JP4451930B2 (enExample) |
| KR (1) | KR100554859B1 (enExample) |
| AU (1) | AU718234B2 (enExample) |
| CA (2) | CA2264552C (enExample) |
| NZ (1) | NZ334512A (enExample) |
| WO (1) | WO1998008480A2 (enExample) |
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| US5605798A (en) | 1993-01-07 | 1997-02-25 | Sequenom, Inc. | DNA diagnostic based on mass spectrometry |
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| AU735416B2 (en) | 1996-11-06 | 2001-07-05 | Sequenom, Inc. | Dna diagnostics based on mass spectrometry |
| DE69735445T2 (de) | 1996-12-10 | 2006-08-10 | Sequenom, Inc., San Diego | Abspaltbare, nicht-flüchtige moleküle zur massenmarkierung |
| AU6139798A (en) * | 1997-02-04 | 1998-08-25 | General Hospital Corporation, The | A novel method for treating epidermal or dermal conditions |
| US5773430A (en) * | 1997-03-13 | 1998-06-30 | Research Foundation Of State University Of New York | Serine proteinase inhibitory activity by hydrophobic tetracycline |
| WO1999030720A1 (en) * | 1997-12-19 | 1999-06-24 | New York University | Method for inhibiting cyclooxygenase-2 and tumor necrosis factor alpha |
| US7189703B2 (en) * | 1998-01-09 | 2007-03-13 | Intracell, Llc | Treatment and diagnosis of alzheimer's disease |
| US6277061B1 (en) * | 1998-03-31 | 2001-08-21 | The Research Foundation Of State University Of New York | Method of inhibiting membrane-type matrix metalloproteinase |
| DE69940227D1 (de) * | 1998-05-08 | 2009-02-12 | Univ Miami | Verwendung von sub-antimikrobiellen tetracyclinen zur Behandlung von okularer Rosacea |
| PT102160B (pt) * | 1998-05-26 | 2001-04-30 | Hovione Sociedade Quimica S A | Processo para a preparacao de 4-(des-dimetilamino)-tetraciclinas |
| US6432934B1 (en) * | 1998-08-06 | 2002-08-13 | Advanced Vision Research | Methods and compositions for topical treatment of eye surface inflammation and related dry eye disease |
| US6015804A (en) * | 1998-09-11 | 2000-01-18 | The Research Foundation Of State University Of New York | Method of using tetracycline compounds to enhance interleukin-10 production |
| US5977091A (en) * | 1998-09-21 | 1999-11-02 | The Research Foundation Of State University Of New York | Method of preventing acute lung injury |
| US6506740B1 (en) | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
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| US6197776B1 (en) * | 1999-03-17 | 2001-03-06 | Ernest L. Bonner, Jr. | Method for treatment of reactive arthritis or bursitis |
| EP1171163A1 (en) * | 1999-04-27 | 2002-01-16 | Antibody Systems, Inc. | Compositions containing tetracyclines for treating hemorrhagic virus infections and other disorders |
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| AU2001268475A1 (en) * | 2000-06-16 | 2002-01-02 | Trustees Of Tufts College | 7-phenyl-substituted tetracycline compounds |
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| US7094806B2 (en) * | 2000-07-07 | 2006-08-22 | Trustees Of Tufts College | 7, 8 and 9-substituted tetracycline compounds |
| EP1303479B1 (en) | 2000-07-07 | 2011-04-06 | Trustees Of Tufts College | 7-, 8- and 9-substituted tetracycline compounds |
| US20050143353A1 (en) * | 2000-07-07 | 2005-06-30 | Paratek Pharmaceuticals, Inc. | 13-Substituted methacycline compounds |
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| US9192615B2 (en) | 2008-08-06 | 2015-11-24 | Medicis Pharmaceutical Corporation | Method for the treatment of acne and certain dosage forms thereof |
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| US8722650B1 (en) | 2005-06-24 | 2014-05-13 | Medicis Pharmaceutical Corporation | Extended-release minocycline dosage forms |
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| US8513223B2 (en) | 2006-12-21 | 2013-08-20 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of inflammatory skin disorders |
| ES2463457T3 (es) | 2006-12-21 | 2014-05-28 | Paratek Pharmaceuticals, Inc. | Derivados de la tetraciclina para el tratamiento de infecciones bacterianas, virales y parasitarias |
| KR20130137696A (ko) * | 2007-03-23 | 2013-12-17 | 몰레큘러 리서치 센터, 인크. | 테트라사이클린류를 함유하는 항염증성 조성물 및 이의 치료 용도 |
| JP2010525069A (ja) * | 2007-04-27 | 2010-07-22 | パラテック ファーマシューティカルズ インコーポレイテッド | アミノアルキルテトラサイクリン化合物の合成方法および精製方法 |
| US9522872B2 (en) * | 2007-07-06 | 2016-12-20 | Paratek Pharmaceuticals, Inc. | Methods for synthesizing substituted tetracycline compounds |
| TW202216656A (zh) | 2008-05-19 | 2022-05-01 | 美商Ｐｒｔｋ Ｓｐｖ２公司 | 四環素化合物之甲苯磺酸鹽及同素異形體 |
| WO2010006292A1 (en) | 2008-07-11 | 2010-01-14 | Neumedics | Tetracycline derivatives with reduced antibiotic activity and neuroprotective benefits |
| HRP20130928T1 (hr) | 2008-08-08 | 2013-11-22 | Tetraphase Pharmaceuticals, Inc. | C7-fluor supstituirani spojevi tetraciklina |
| KR101290745B1 (ko) | 2010-06-03 | 2013-07-29 | 한국해양과학기술원 | 라말린을 함유하는 염증질환 또는 면역질환의 예방 또는 치료용 약학 조성물 |
| US9315451B2 (en) | 2009-05-08 | 2016-04-19 | Tetraphase Pharmaceuticals, Inc. | Tetracycline compounds |
| DK2470500T3 (en) | 2009-08-28 | 2018-01-08 | Tetraphase Pharmaceuticals Inc | tetracycline |
| JP5820462B2 (ja) | 2010-03-31 | 2015-11-24 | テトラフェース ファーマシューティカルズ，インコーポレイテッド | 多環式テトラサイクリン化合物 |
| US8455436B2 (en) | 2010-12-28 | 2013-06-04 | Depuy Mitek, Llc | Compositions and methods for treating joints |
| US8524662B2 (en) | 2010-12-28 | 2013-09-03 | Depuy Mitek, Llc | Compositions and methods for treating joints |
| US8398611B2 (en) | 2010-12-28 | 2013-03-19 | Depuy Mitek, Inc. | Compositions and methods for treating joints |
| ES2739626T3 (es) | 2011-05-12 | 2020-02-03 | Paratek Pharm Innc | Sales cristalinas de amida del ácido (4S,4aS,5aR,12aS)-4-dimetilamino-3,10,12,12a-tetrahidroxi-7-[(metoxi(metil)amino)-metil]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahidro-naftacen-2-carboxílico y métodos de uso de las mismas |
| US9119793B1 (en) | 2011-06-28 | 2015-09-01 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for doxycycline |
| US9561241B1 (en) | 2011-06-28 | 2017-02-07 | Medicis Pharmaceutical Corporation | Gastroretentive dosage forms for minocycline |
| US8623839B2 (en) | 2011-06-30 | 2014-01-07 | Depuy Mitek, Llc | Compositions and methods for stabilized polysaccharide formulations |
| EP2872146A4 (en) * | 2012-07-13 | 2016-01-06 | Paratek Pharm Innc | TETRACYCLIN COMPOUNDS FOR THE TREATMENT OF NEURODEEGENERATIVE DISEASES |
| CN108329312B (zh) | 2012-08-31 | 2021-12-31 | 四相制药公司 | 四环素化合物 |
| US10842802B2 (en) | 2013-03-15 | 2020-11-24 | Medicis Pharmaceutical Corporation | Controlled release pharmaceutical dosage forms |
| US9682099B2 (en) | 2015-01-20 | 2017-06-20 | DePuy Synthes Products, Inc. | Compositions and methods for treating joints |
| HUE066360T2 (hu) | 2016-10-19 | 2024-07-28 | Tetraphase Pharmaceuticals Inc | Eravaciklin kristályformái |
| FR3081559B1 (fr) * | 2018-05-28 | 2020-05-08 | Noptrack | Procede pour detecter une pathologie par reperage d'une quantite de no produite par le sujet etudie et appareil pour la mise en œuvre dudit procede |
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| FR3103901B1 (fr) * | 2019-11-28 | 2023-02-24 | Noptrack | Detection d’une espece chimique dans la sueur d’un sujet |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478946A (en) * | 1989-06-21 | 1995-12-26 | Abbott Laboratories | Guanidino compounds as regulators of nitric oxide synthase |
| US5216025A (en) * | 1989-09-13 | 1993-06-01 | Board Of Regents, The University Of Texas System | Nitric oxide synthesis inhibitors for potentiating the action of pressor agents in certain hypotensive patients |
| US5358969A (en) * | 1991-12-16 | 1994-10-25 | Washington University | Method of inhibiting nitric oxide formation |
| US5246971A (en) * | 1991-12-16 | 1993-09-21 | Washington University | Method of inhibiting nitric oxide formation |
| US5246970A (en) * | 1991-12-16 | 1993-09-21 | Washington University | Method of inhibiting nitric oxide formation |
| GB9200114D0 (en) * | 1992-01-04 | 1992-02-26 | Scras | Dual inhibitors of no synthase and cyclooxygenase |
| US5296466A (en) * | 1992-02-19 | 1994-03-22 | Board Of Regents, The University Of Texas System | Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein |
| US5266594A (en) * | 1992-05-12 | 1993-11-30 | Dawson Valina L | Inhibitors of nitric oxide synthase and use thereof to prevent glutamate neurotoxicity |
| US5258371A (en) * | 1992-05-29 | 1993-11-02 | Kuraray Co., Ltd. | Method to reduce connective tissue destruction |
| WO1994012645A2 (en) * | 1992-11-25 | 1994-06-09 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | cDNA CLONE FOR HUMAN INDUCIBLE NITRIC OXYDE SYNTHASE AND PROCESS FOR PREPARING SAME |
| US5449688A (en) * | 1993-03-30 | 1995-09-12 | The United States Of America As Represented By The Department Of Health And Human Services | Method of treating chronic inflammatory diseases |
-
1996
- 1996-08-30 US US08/697,815 patent/US5789395A/en not_active Expired - Lifetime
-
1997
- 1997-08-21 AU AU40808/97A patent/AU718234B2/en not_active Expired
- 1997-08-21 KR KR1019997001591A patent/KR100554859B1/ko not_active Expired - Lifetime
- 1997-08-21 JP JP51173598A patent/JP4451930B2/ja not_active Expired - Lifetime
- 1997-08-21 EP EP97938501A patent/EP0966525A4/en not_active Ceased
- 1997-08-21 CA CA002264552A patent/CA2264552C/en not_active Expired - Lifetime
- 1997-08-21 CA CA002670296A patent/CA2670296A1/en not_active Abandoned
- 1997-08-21 WO PCT/US1997/014723 patent/WO1998008480A2/en not_active Ceased
- 1997-08-21 NZ NZ334512A patent/NZ334512A/xx not_active IP Right Cessation
-
1998
- 1998-04-16 US US09/061,286 patent/US5919775A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| NZ334512A (en) | 2000-09-29 |
| EP0966525A4 (en) | 2004-04-14 |
| KR100554859B1 (ko) | 2006-02-24 |
| EP0966525A1 (en) | 1999-12-29 |
| JP4451930B2 (ja) | 2010-04-14 |
| CA2670296A1 (en) | 1998-03-05 |
| US5919775A (en) | 1999-07-06 |
| CA2264552A1 (en) | 1998-03-05 |
| KR20000035881A (ko) | 2000-06-26 |
| US5789395A (en) | 1998-08-04 |
| AU718234B2 (en) | 2000-04-13 |
| WO1998008480A2 (en) | 1998-03-05 |
| JP2002513386A (ja) | 2002-05-08 |
| WO1998008480A3 (en) | 2004-07-01 |
| AU4080897A (en) | 1998-03-19 |
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