CA2235804A1 - Methods and compositions for detection of specific nucleotide sequences - Google Patents
Methods and compositions for detection of specific nucleotide sequences Download PDFInfo
- Publication number
- CA2235804A1 CA2235804A1 CA002235804A CA2235804A CA2235804A1 CA 2235804 A1 CA2235804 A1 CA 2235804A1 CA 002235804 A CA002235804 A CA 002235804A CA 2235804 A CA2235804 A CA 2235804A CA 2235804 A1 CA2235804 A1 CA 2235804A1
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- Prior art keywords
- nucleic acid
- pnas
- dna
- methods
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
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- Immunology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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| AU730154B2 (en) | 1995-10-27 | 2001-03-01 | Elliot R. Ramberg | Methods and compositions for detection of specific nucleotide sequences |
| US20050069923A1 (en) * | 1996-07-08 | 2005-03-31 | Mullis Kary Banks | Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus |
| WO1999024621A2 (en) * | 1997-11-12 | 1999-05-20 | Cygene, Inc. | Methods and compositions for detection of specific nucleotide sequences |
| EP1135525A2 (en) * | 1998-11-19 | 2001-09-26 | Cygene, Inc. | Methods and compositions for detection of nucleic acid sequences and signal amplification |
| AU7569600A (en) | 1999-05-20 | 2000-12-28 | Illumina, Inc. | Combinatorial decoding of random nucleic acid arrays |
| AU781934B2 (en) * | 1999-07-09 | 2005-06-23 | Gen-Probe Incorporated | Detection of HIV-1 by nucleic acid amplification |
| AU1468201A (en) * | 1999-11-03 | 2001-05-14 | Cygene, Inc. | Methods and compositions for analysis of snps and strs |
| CA2397341A1 (en) * | 2000-01-13 | 2001-07-19 | Dhanesh Gohel | Ferrofluid based arrays |
| GB0008618D0 (en) * | 2000-04-08 | 2000-05-31 | Univ Strathclyde | Analyte detection & apparatus therefor |
| DE60125312T2 (de) * | 2000-10-26 | 2007-06-06 | Agilent Technologies, Inc. (n.d. Ges. d. Staates Delaware), Santa Clara | Mikroarray |
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| AU2002357178A1 (en) * | 2001-12-14 | 2003-06-30 | Cygene, Inc. | Diagnostic assays for bcwa |
| CA2471018A1 (en) * | 2002-01-28 | 2003-08-07 | Burstein Technologies, Inc. | Methods and apparatus for logical triggering of an optical bio-disc |
| CN1625689A (zh) | 2002-01-31 | 2005-06-08 | 长冈实业株式会社 | 通过盘槽以及相关光分析盘触发的方法和系统 |
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| JP2005533256A (ja) * | 2002-07-17 | 2005-11-04 | ユー．エス． ジェノミクス， インコーポレイテッド | キメラタグを用いるポリマーを分析するための方法と組成物 |
| WO2004011606A2 (en) * | 2002-07-26 | 2004-02-05 | Alfa Wasserman, Inc. | Macromolecular protection assay |
| AU2003291765A1 (en) * | 2002-11-04 | 2004-06-07 | Cygene Laboratories, Inc. | Target sequences for the detection of the west nile virus |
| US20040142329A1 (en) * | 2003-01-17 | 2004-07-22 | Ingeneus Corporation | Probe conjugation to increase multiplex binding motif preference |
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| WO2006026654A2 (en) | 2004-08-27 | 2006-03-09 | Exact Sciences Corporation | Method for detecting a recombinant event |
| KR20070062575A (ko) * | 2004-09-24 | 2007-06-15 | 인제네우스 인크. | 게놈 분석 |
| WO2006047787A2 (en) | 2004-10-27 | 2006-05-04 | Exact Sciences Corporation | Method for monitoring disease progression or recurrence |
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| US8247419B2 (en) * | 2005-06-09 | 2012-08-21 | Bristol-Myers Squibb Company | Methods of identifying and treating individuals exhibiting mutant kit protein |
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| US7642049B2 (en) * | 2006-06-30 | 2010-01-05 | Bristol-Myers Squibb Company | Method for identifying HIV-1 protease inhibitors with reduced metabolic affects through detection of human resistin polymorphisms |
| WO2008052774A2 (en) * | 2006-10-31 | 2008-05-08 | Noxxon Pharma Ag | Methods for detection of a single- or double-stranded nucleic acid molecule |
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| US20110020797A1 (en) * | 2007-02-09 | 2011-01-27 | Bristol-Myers Squibb Company | Methods For Identifying Patients With An Increased Likelihood Of Responding To DPP-IV Inhibitors |
| ES3045958T3 (en) * | 2007-07-17 | 2025-12-01 | Somalogic Operating Co Inc | Method for generating aptamers with improved off-rates |
| WO2009140685A2 (en) | 2008-05-16 | 2009-11-19 | Bristol-Myers Squibb Company | Methods for identifying subjects with an increased likelihood of responding to dpp-iv inhibitors |
| WO2011109642A1 (en) | 2010-03-03 | 2011-09-09 | Somalogic, Inc. | Aptamers to 4-1bb and their use in treating diseases and disorders |
| NZ602618A (en) | 2010-04-12 | 2013-12-20 | Somalogic Inc | Aptamers to beta-ngf and their use in treating beta-ngf mediated diseases and disorders |
| US10752940B2 (en) * | 2013-11-08 | 2020-08-25 | Ionis Pharmaceuticals, Inc. | Compounds and methods for detecting oligonucleotides |
| KR102798620B1 (ko) * | 2018-06-07 | 2025-04-22 | 암젠 인크 | 단백질-폴리뉴클레오티드 접합체에 대한 검출 검정 |
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| US4775619A (en) * | 1984-10-16 | 1988-10-04 | Chiron Corporation | Polynucleotide determination with selectable cleavage sites |
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| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| FR2596773B1 (fr) | 1986-04-04 | 1988-06-24 | Pasteur Institut | Sonde monocatenaire marquee, non radioactive, procede pour sa fabrication et procede de detection d'une sequence nucleotidique determinee a l'aide de cette sonde |
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| US5482836A (en) * | 1993-01-14 | 1996-01-09 | The Regents Of The University Of California | DNA purification by triplex-affinity capture and affinity capture electrophoresis |
| US5518901A (en) * | 1993-04-19 | 1996-05-21 | Murtagh; James J. | Methods for adapting nucleic acid for detection, sequencing, and cloning using exonuclease |
| DE4344742A1 (de) * | 1993-06-09 | 1994-12-15 | Boehringer Mannheim Gmbh | Verfahren zur Immobilisierung von Nukleinsäuren |
| US5726297A (en) | 1994-03-18 | 1998-03-10 | Lynx Therapeutics, Inc. | Oligodeoxyribonucleotide N3' P5' phosphoramidates |
| US5599922A (en) | 1994-03-18 | 1997-02-04 | Lynx Therapeutics, Inc. | Oligonucleotide N3'-P5' phosphoramidates: hybridization and nuclease resistance properties |
| US5714328A (en) | 1995-06-07 | 1998-02-03 | Board Of Regents, The University Of Texas System | RNA photocleavage using texaphyrins |
| AU730154B2 (en) | 1995-10-27 | 2001-03-01 | Elliot R. Ramberg | Methods and compositions for detection of specific nucleotide sequences |
| US5834198A (en) | 1996-03-21 | 1998-11-10 | Boehringer Mamnnheim Gmbh | Selective photoinducted flavin-dependent cleavage of RNA at G-U base pairs and kits therefor |
-
1996
- 1996-10-25 AU AU11568/97A patent/AU730154B2/en not_active Ceased
- 1996-10-25 WO PCT/US1996/017191 patent/WO1997015691A1/en not_active Ceased
- 1996-10-25 JP JP9516836A patent/JPH11513887A/ja not_active Ceased
- 1996-10-25 KR KR1019980703020A patent/KR19990067080A/ko not_active Ceased
- 1996-10-25 US US08/739,069 patent/US5962225A/en not_active Expired - Fee Related
- 1996-10-25 CA CA002235804A patent/CA2235804A1/en not_active Abandoned
- 1996-10-25 EP EP96942723A patent/EP0864002A4/en not_active Withdrawn
-
1998
- 1998-04-27 MX MX9803308A patent/MX9803308A/es unknown
-
1999
- 1999-05-17 US US09/313,121 patent/US6100040A/en not_active Expired - Fee Related
-
2000
- 2000-08-07 US US09/633,848 patent/US6458540B1/en not_active Expired - Fee Related
-
2001
- 2001-11-05 US US09/992,128 patent/US20020119475A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU1156897A (en) | 1997-05-15 |
| US20020119475A1 (en) | 2002-08-29 |
| KR19990067080A (ko) | 1999-08-16 |
| AU730154B2 (en) | 2001-03-01 |
| JPH11513887A (ja) | 1999-11-30 |
| US6458540B1 (en) | 2002-10-01 |
| US6100040A (en) | 2000-08-08 |
| WO1997015691A1 (en) | 1997-05-01 |
| US5962225A (en) | 1999-10-05 |
| EP0864002A4 (en) | 1999-07-28 |
| MX9803308A (es) | 1998-11-29 |
| EP0864002A1 (en) | 1998-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |