JPH11513887A - 特定のヌクレオチド配列の検出方法および組成物 - Google Patents

特定のヌクレオチド配列の検出方法および組成物

Info

Publication number
JPH11513887A
JPH11513887A JP9516836A JP51683697A JPH11513887A JP H11513887 A JPH11513887 A JP H11513887A JP 9516836 A JP9516836 A JP 9516836A JP 51683697 A JP51683697 A JP 51683697A JP H11513887 A JPH11513887 A JP H11513887A
Authority
JP
Japan
Prior art keywords
nucleic acid
pnas
dna
acid sequence
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP9516836A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11513887A5 (enExample
Inventor
ランバーグ，エリオット，アール．
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPH11513887A publication Critical patent/JPH11513887A/ja
Publication of JPH11513887A5 publication Critical patent/JPH11513887A5/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
JP9516836A 1995-10-27 1996-10-25 特定のヌクレオチド配列の検出方法および組成物 Ceased JPH11513887A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US593895P 1995-10-27 1995-10-27
US60/005,938 1995-10-27
PCT/US1996/017191 WO1997015691A1 (en) 1995-10-27 1996-10-25 Methods and compositions for detection of specific nucleotide sequences

Publications (2)

Publication Number Publication Date
JPH11513887A true JPH11513887A (ja) 1999-11-30
JPH11513887A5 JPH11513887A5 (enExample) 2004-10-14

Family

ID=21718453

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9516836A Ceased JPH11513887A (ja) 1995-10-27 1996-10-25 特定のヌクレオチド配列の検出方法および組成物

Country Status (8)

Country Link
US (4) US5962225A (enExample)
EP (1) EP0864002A4 (enExample)
JP (1) JPH11513887A (enExample)
KR (1) KR19990067080A (enExample)
AU (1) AU730154B2 (enExample)
CA (1) CA2235804A1 (enExample)
MX (1) MX9803308A (enExample)
WO (1) WO1997015691A1 (enExample)

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AU730154B2 (en) 1995-10-27 2001-03-01 Elliot R. Ramberg Methods and compositions for detection of specific nucleotide sequences
US20050069923A1 (en) * 1996-07-08 2005-03-31 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
WO1999024621A2 (en) * 1997-11-12 1999-05-20 Cygene, Inc. Methods and compositions for detection of specific nucleotide sequences
EP1135525A2 (en) * 1998-11-19 2001-09-26 Cygene, Inc. Methods and compositions for detection of nucleic acid sequences and signal amplification
AU7569600A (en) 1999-05-20 2000-12-28 Illumina, Inc. Combinatorial decoding of random nucleic acid arrays
AU781934B2 (en) * 1999-07-09 2005-06-23 Gen-Probe Incorporated Detection of HIV-1 by nucleic acid amplification
AU1468201A (en) * 1999-11-03 2001-05-14 Cygene, Inc. Methods and compositions for analysis of snps and strs
CA2397341A1 (en) * 2000-01-13 2001-07-19 Dhanesh Gohel Ferrofluid based arrays
GB0008618D0 (en) * 2000-04-08 2000-05-31 Univ Strathclyde Analyte detection & apparatus therefor
DE60125312T2 (de) * 2000-10-26 2007-06-06 Agilent Technologies, Inc. (n.d. Ges. d. Staates Delaware), Santa Clara Mikroarray
EP1921451A3 (en) 2001-05-22 2008-05-28 Cygene, Inc. Complement mediated assays for in vivo and in vitro methods
AU2002357178A1 (en) * 2001-12-14 2003-06-30 Cygene, Inc. Diagnostic assays for bcwa
CA2471018A1 (en) * 2002-01-28 2003-08-07 Burstein Technologies, Inc. Methods and apparatus for logical triggering of an optical bio-disc
CN1625689A (zh) 2002-01-31 2005-06-08 长冈实业株式会社 通过盘槽以及相关光分析盘触发的方法和系统
US7776524B2 (en) 2002-02-15 2010-08-17 Genzyme Corporation Methods for analysis of molecular events
JP2005533256A (ja) * 2002-07-17 2005-11-04 ユー．エス． ジェノミクス， インコーポレイテッド キメラタグを用いるポリマーを分析するための方法と組成物
WO2004011606A2 (en) * 2002-07-26 2004-02-05 Alfa Wasserman, Inc. Macromolecular protection assay
AU2003291765A1 (en) * 2002-11-04 2004-06-07 Cygene Laboratories, Inc. Target sequences for the detection of the west nile virus
US20040142329A1 (en) * 2003-01-17 2004-07-22 Ingeneus Corporation Probe conjugation to increase multiplex binding motif preference
JP3923917B2 (ja) * 2003-03-26 2007-06-06 株式会社東芝 ターゲットの製造方法、標的配列検出方法、ターゲットおよび標的配列検出用アッセイキット
EP1627082B1 (en) * 2003-05-13 2009-07-15 Gen-Probe Incorporated Method and kit for identifying antibiotic-resistant microorganisms
WO2006026654A2 (en) 2004-08-27 2006-03-09 Exact Sciences Corporation Method for detecting a recombinant event
KR20070062575A (ko) * 2004-09-24 2007-06-15 인제네우스 인크. 게놈 분석
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
US8247419B2 (en) * 2005-06-09 2012-08-21 Bristol-Myers Squibb Company Methods of identifying and treating individuals exhibiting mutant kit protein
US20070202512A1 (en) * 2005-08-19 2007-08-30 Bristol-Myers Squibb Company Human single nucleotide polymorphisms associated with dose-dependent weight gain and methods of use thereof
US7855051B2 (en) * 2005-09-12 2010-12-21 Research & Diagnostic Systems, Inc. Mycoplasma detection method and composition
WO2007056177A2 (en) * 2005-11-04 2007-05-18 Bristol-Myers Squibb Pharma Company T315a and f317i mutations of bcr-abl kinase domain
EP2644615B1 (en) * 2006-02-08 2017-04-05 Becton Dickinson and Company SERS nanotag assays
WO2007109527A1 (en) * 2006-03-17 2007-09-27 Bristol-Myers Squibb Company Methods of identifying and treating individuals exhibiting mutant bcr/abl kinase polypeptides
US7642049B2 (en) * 2006-06-30 2010-01-05 Bristol-Myers Squibb Company Method for identifying HIV-1 protease inhibitors with reduced metabolic affects through detection of human resistin polymorphisms
WO2008052774A2 (en) * 2006-10-31 2008-05-08 Noxxon Pharma Ag Methods for detection of a single- or double-stranded nucleic acid molecule
US7947447B2 (en) 2007-01-16 2011-05-24 Somalogic, Inc. Method for generating aptamers with improved off-rates
US20110020797A1 (en) * 2007-02-09 2011-01-27 Bristol-Myers Squibb Company Methods For Identifying Patients With An Increased Likelihood Of Responding To DPP-IV Inhibitors
ES3045958T3 (en) * 2007-07-17 2025-12-01 Somalogic Operating Co Inc Method for generating aptamers with improved off-rates
WO2009140685A2 (en) 2008-05-16 2009-11-19 Bristol-Myers Squibb Company Methods for identifying subjects with an increased likelihood of responding to dpp-iv inhibitors
WO2011109642A1 (en) 2010-03-03 2011-09-09 Somalogic, Inc. Aptamers to 4-1bb and their use in treating diseases and disorders
NZ602618A (en) 2010-04-12 2013-12-20 Somalogic Inc Aptamers to beta-ngf and their use in treating beta-ngf mediated diseases and disorders
US10752940B2 (en) * 2013-11-08 2020-08-25 Ionis Pharmaceuticals, Inc. Compounds and methods for detecting oligonucleotides
KR102798620B1 (ko) * 2018-06-07 2025-04-22 암젠 인크 단백질-폴리뉴클레오티드 접합체에 대한 검출 검정

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US4775619A (en) * 1984-10-16 1988-10-04 Chiron Corporation Polynucleotide determination with selectable cleavage sites
US5258506A (en) 1984-10-16 1993-11-02 Chiron Corporation Photolabile reagents for incorporation into oligonucleotide chains
US4683202A (en) * 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4683195A (en) * 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
FR2596773B1 (fr) 1986-04-04 1988-06-24 Pasteur Institut Sonde monocatenaire marquee, non radioactive, procede pour sa fabrication et procede de detection d'une sequence nucleotidique determinee a l'aide de cette sonde
US5422251A (en) 1986-11-26 1995-06-06 Princeton University Triple-stranded nucleic acids
US5176996A (en) * 1988-12-20 1993-01-05 Baylor College Of Medicine Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use
US5273881A (en) * 1990-05-07 1993-12-28 Daikin Industries, Ltd. Diagnostic applications of double D-loop formation
CA2095624C (en) * 1990-11-09 2000-06-13 Rafael D. Camerini-Otero Method of targeting dna
EP0492570B1 (en) * 1990-12-24 2001-05-02 Enzo Diagnostics, Inc. Method for detecting a target polynucleotide in a sample using a background reducing reagent and composition and kit comprising such a reagent
US5607924A (en) 1992-01-21 1997-03-04 Pharmacyclics, Inc. DNA photocleavage using texaphyrins
WO1993018187A1 (en) * 1992-03-13 1993-09-16 California Institute Of Technology Triple helix recognition of dna
US5583032A (en) 1992-10-21 1996-12-10 The Cleveland Clinic Foundation And National Institutes Of Health Method of cleaving specific strands of RNA
US5422253A (en) 1992-12-07 1995-06-06 Wisconsin Alumni Research Foundation Method of site specific nucleic acid cleavage
US5482836A (en) * 1993-01-14 1996-01-09 The Regents Of The University Of California DNA purification by triplex-affinity capture and affinity capture electrophoresis
US5518901A (en) * 1993-04-19 1996-05-21 Murtagh; James J. Methods for adapting nucleic acid for detection, sequencing, and cloning using exonuclease
DE4344742A1 (de) * 1993-06-09 1994-12-15 Boehringer Mannheim Gmbh Verfahren zur Immobilisierung von Nukleinsäuren
US5726297A (en) 1994-03-18 1998-03-10 Lynx Therapeutics, Inc. Oligodeoxyribonucleotide N3' P5' phosphoramidates
US5599922A (en) 1994-03-18 1997-02-04 Lynx Therapeutics, Inc. Oligonucleotide N3'-P5' phosphoramidates: hybridization and nuclease resistance properties
US5714328A (en) 1995-06-07 1998-02-03 Board Of Regents, The University Of Texas System RNA photocleavage using texaphyrins
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US5834198A (en) 1996-03-21 1998-11-10 Boehringer Mamnnheim Gmbh Selective photoinducted flavin-dependent cleavage of RNA at G-U base pairs and kits therefor

Also Published As

Publication number Publication date
AU1156897A (en) 1997-05-15
US20020119475A1 (en) 2002-08-29
KR19990067080A (ko) 1999-08-16
AU730154B2 (en) 2001-03-01
US6458540B1 (en) 2002-10-01
US6100040A (en) 2000-08-08
CA2235804A1 (en) 1997-05-01
WO1997015691A1 (en) 1997-05-01
US5962225A (en) 1999-10-05
EP0864002A4 (en) 1999-07-28
MX9803308A (es) 1998-11-29
EP0864002A1 (en) 1998-09-16

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