CA2225282A1 - Isochromans 1,6-disubstitues destines au traitement des cephalees de type migraine - Google Patents
Isochromans 1,6-disubstitues destines au traitement des cephalees de type migraine Download PDFInfo
- Publication number
- CA2225282A1 CA2225282A1 CA002225282A CA2225282A CA2225282A1 CA 2225282 A1 CA2225282 A1 CA 2225282A1 CA 002225282 A CA002225282 A CA 002225282A CA 2225282 A CA2225282 A CA 2225282A CA 2225282 A1 CA2225282 A1 CA 2225282A1
- Authority
- CA
- Canada
- Prior art keywords
- ethyl
- defined above
- isochroman
- alkyl
- piperazinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/76—Benzo[c]pyrans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74195P | 1995-06-30 | 1995-06-30 | |
| US60/000,741 | 1995-06-30 | ||
| US1123496P | 1996-02-06 | 1996-02-06 | |
| US60/011,234 | 1996-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2225282A1 true CA2225282A1 (fr) | 1997-01-23 |
Family
ID=26668092
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002225282A Abandoned CA2225282A1 (fr) | 1995-06-30 | 1996-06-07 | Isochromans 1,6-disubstitues destines au traitement des cephalees de type migraine |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP0836599A1 (fr) |
| JP (1) | JPH11509532A (fr) |
| AU (1) | AU6252296A (fr) |
| BR (1) | BR9609631A (fr) |
| CA (1) | CA2225282A1 (fr) |
| CZ (1) | CZ418597A3 (fr) |
| FI (1) | FI974640A0 (fr) |
| MX (1) | MX9710260A (fr) |
| NO (1) | NO976112L (fr) |
| PL (1) | PL324319A1 (fr) |
| SK (1) | SK164297A3 (fr) |
| WO (1) | WO1997002259A1 (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2370270A (en) * | 2000-12-20 | 2002-06-26 | Lilly Co Eli | Pharmaceutical compounds |
| GB0130339D0 (en) * | 2001-12-19 | 2002-02-06 | Lilly Co Eli | Isochroman compounds |
| US7335660B2 (en) | 2001-12-19 | 2008-02-26 | Eli Lilly And Company | Isochroman compounds for treatment of CNS disorders |
| US7110576B2 (en) | 2002-12-30 | 2006-09-19 | Pitney Bowes Inc. | System and method for authenticating a mailpiece sender |
| ATE458727T1 (de) | 2004-05-05 | 2010-03-15 | Hoffmann La Roche | Zur modulation des 5-ht6-rezeptors, des 5-ht2a- rezeptors oder beider rezeptoren geeignete arylsulfonylbenzodioxane |
| PL1831152T3 (pl) | 2004-12-21 | 2009-03-31 | Hoffmann La Roche | Pochodne tetraliny i indanu oraz ich zastosowanie jako antagonistów 5-HT |
| SI1831159T1 (sl) | 2004-12-21 | 2010-04-30 | Hoffmann La Roche | Derivati tetralina in indana ter njune uporabe |
| CN101119989B (zh) | 2004-12-21 | 2010-06-09 | 弗·哈夫曼-拉罗切有限公司 | 色满衍生物及其在治疗cns疾病中的用途 |
| CA2591793A1 (fr) | 2004-12-21 | 2006-06-29 | F. Hoffmann-La Roche Ag | Derives de tetraline et d'indane, et utilisations de ceux-ci |
| ATE396183T1 (de) | 2004-12-21 | 2008-06-15 | Hoffmann La Roche | Chromanderivate und ihre verwendung als liganden des 5-ht-rezeptors |
| WO2007051735A1 (fr) | 2005-11-03 | 2007-05-10 | F. Hoffmann-La Roche Ag | Dérivés d'indolylmaléimide en tant qu'inhibiteurs de protéine kinase |
| AU2007263084A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Tetralin and indane derivatives and uses thereof |
| AU2007263075A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonamidyl tetralin derivatives and uses thereof |
| AU2007263076A1 (en) | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonyl naphthalene derivatives and uses thereof |
| JP2010229128A (ja) * | 2009-03-05 | 2010-10-14 | Sumitomo Chemical Co Ltd | ハロゲン置換テレフタル酸ジアミド化合物、その製造方法及び該化合物を用いたハロゲン置換ベンゼンジメタノールの製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1552004A (en) * | 1976-05-26 | 1979-09-05 | Takeda Chemical Industries Ltd | Isochroman derivatives |
| ATE182590T1 (de) * | 1993-12-28 | 1999-08-15 | Upjohn Co | Heterozyklische verbindungen für die behandlung von kardiovaskular- und zentralnervensystem störungen |
-
1996
- 1996-06-07 PL PL96324319A patent/PL324319A1/xx unknown
- 1996-06-07 MX MX9710260A patent/MX9710260A/es unknown
- 1996-06-07 CA CA002225282A patent/CA2225282A1/fr not_active Abandoned
- 1996-06-07 AU AU62522/96A patent/AU6252296A/en not_active Abandoned
- 1996-06-07 SK SK1642-97A patent/SK164297A3/sk unknown
- 1996-06-07 WO PCT/US1996/008681 patent/WO1997002259A1/fr not_active Application Discontinuation
- 1996-06-07 EP EP96921264A patent/EP0836599A1/fr not_active Withdrawn
- 1996-06-07 JP JP9505135A patent/JPH11509532A/ja active Pending
- 1996-06-07 CZ CZ974185A patent/CZ418597A3/cs unknown
- 1996-06-07 BR BR9609631A patent/BR9609631A/pt not_active Application Discontinuation
-
1997
- 1997-12-29 NO NO976112A patent/NO976112L/no unknown
- 1997-12-30 FI FI974640A patent/FI974640A0/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI974640A (fi) | 1997-12-30 |
| BR9609631A (pt) | 1999-03-02 |
| CZ418597A3 (cs) | 1998-06-17 |
| NO976112L (no) | 1998-03-02 |
| NO976112D0 (no) | 1997-12-29 |
| PL324319A1 (en) | 1998-05-25 |
| FI974640A0 (fi) | 1997-12-30 |
| WO1997002259A1 (fr) | 1997-01-23 |
| MX9710260A (es) | 1998-03-29 |
| SK164297A3 (en) | 1998-09-09 |
| JPH11509532A (ja) | 1999-08-24 |
| EP0836599A1 (fr) | 1998-04-22 |
| AU6252296A (en) | 1997-02-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |