CA2222551A1 - Epitopes associes a une tumeur - Google Patents

Epitopes associes a une tumeur Download PDF

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Publication number
CA2222551A1
CA2222551A1 CA002222551A CA2222551A CA2222551A1 CA 2222551 A1 CA2222551 A1 CA 2222551A1 CA 002222551 A CA002222551 A CA 002222551A CA 2222551 A CA2222551 A CA 2222551A CA 2222551 A1 CA2222551 A1 CA 2222551A1
Authority
CA
Canada
Prior art keywords
ser
leu
gly
ala
asp
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002222551A
Other languages
English (en)
Inventor
Sandra M. Butler
Nicholas Pomato
Ebo Bos
Michael G. Hanna, Jr.
Martin V. Haspel
Herbert C. Hoover, Jr.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2222551A1 publication Critical patent/CA2222551A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne des épitopes auxquels l'anticorps monoclonal 88BV59 et l'anticorps 16.88 réagissent. Ces anticorps ont été produits par des lignées de lymphocytes B dérivées de lymphocytes B de patients atteints de cancer, activement immunisés par des antigènes tumoraux autologues. Ces antigènes que l'on trouve sur le même antigène de tissu tumoral, peuvent être utilisés à la fois dans des procédures diagnostiques et thérapeutiques relatives aux cancers humains.
CA002222551A 1995-06-07 1996-06-06 Epitopes associes a une tumeur Abandoned CA2222551A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47859195A 1995-06-07 1995-06-07
US08/478,591 1995-06-07

Publications (1)

Publication Number Publication Date
CA2222551A1 true CA2222551A1 (fr) 1996-12-19

Family

ID=23900547

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002222551A Abandoned CA2222551A1 (fr) 1995-06-07 1996-06-06 Epitopes associes a une tumeur

Country Status (7)

Country Link
US (1) US5951985A (fr)
EP (1) EP0831895A1 (fr)
JP (1) JPH11508235A (fr)
KR (1) KR19990022406A (fr)
AU (1) AU713538B2 (fr)
CA (1) CA2222551A1 (fr)
WO (1) WO1996040227A1 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7052830B1 (en) 1998-06-09 2006-05-30 Branch Andrea D Hepatitis C virus peptides and uses thereof
ES2281179T3 (es) * 1998-06-09 2007-09-16 Andrea D. Branch Nuevos peptidos del virus de la hepatitis c y usos de los mismos.
WO2003024191A2 (fr) * 2001-09-21 2003-03-27 Raven Biotechnologies, Inc. Anticorps se fixant a l'antigene cytokeratine 8 associe au cancer et procedes d'utilisation correspondants
US20150231077A1 (en) 2014-02-17 2015-08-20 The Cleveland Clinic Foundation Amine passivated nanoparticles for cancer treatment and imaging
US20170226171A1 (en) * 2016-02-09 2017-08-10 Vaccinogen, Inc. Adenocarcinoma antigenic determinants and methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4828991A (en) * 1984-01-31 1989-05-09 Akzo N.V. Tumor specific monoclonal antibodies
US5106738A (en) * 1984-01-31 1992-04-21 Akzo Nv Tumor specific monoclonal antibodies
US5474755A (en) * 1984-01-31 1995-12-12 Akzo Nobel N.V. Tumor associated monoclonal antibodies
US4997762A (en) * 1984-01-31 1991-03-05 Akzo N.V. Tumor associated monocoloal antibodies derived from human B-cell line
US4810781A (en) * 1987-01-15 1989-03-07 The George Washington University Methods of preparing epitopes of tumor associated antigens
US5338832A (en) * 1987-07-02 1994-08-16 Akzo N.V. Antigen recognized by MCA 16-88

Also Published As

Publication number Publication date
AU6046996A (en) 1996-12-30
AU713538B2 (en) 1999-12-02
US5951985A (en) 1999-09-14
JPH11508235A (ja) 1999-07-21
KR19990022406A (ko) 1999-03-25
WO1996040227A1 (fr) 1996-12-19
EP0831895A1 (fr) 1998-04-01

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued