CA2155129C - Combinations of retroviral inhibitors - Google Patents

Combinations of retroviral inhibitors

Info

Publication number
CA2155129C
CA2155129C CA002155129A CA2155129A CA2155129C CA 2155129 C CA2155129 C CA 2155129C CA 002155129 A CA002155129 A CA 002155129A CA 2155129 A CA2155129 A CA 2155129A CA 2155129 C CA2155129 C CA 2155129C
Authority
CA
Canada
Prior art keywords
benzyl
compound
formula
compounds
benzyloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002155129A
Other languages
English (en)
French (fr)
Other versions
CA2155129A1 (en
Inventor
A. Stanley Tyms
Debra L. Taylor
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of CA2155129A1 publication Critical patent/CA2155129A1/en
Application granted granted Critical
Publication of CA2155129C publication Critical patent/CA2155129C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA002155129A 1993-02-22 1994-01-18 Combinations of retroviral inhibitors Expired - Fee Related CA2155129C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939303518A GB9303518D0 (en) 1993-02-22 1993-02-22 Combinations of retroviral inhibitors
GB9303518.6 1993-02-22

Publications (2)

Publication Number Publication Date
CA2155129A1 CA2155129A1 (en) 1994-09-01
CA2155129C true CA2155129C (en) 1999-04-13

Family

ID=10730826

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002155129A Expired - Fee Related CA2155129C (en) 1993-02-22 1994-01-18 Combinations of retroviral inhibitors

Country Status (14)

Country Link
EP (1) EP0684836A1 (zh)
JP (1) JPH08509469A (zh)
KR (1) KR100293299B1 (zh)
CN (1) CN1118142A (zh)
AU (1) AU679497B2 (zh)
CA (1) CA2155129C (zh)
GB (1) GB9303518D0 (zh)
HU (1) HUT72493A (zh)
IL (1) IL108696A (zh)
MX (1) MXPA94001311A (zh)
NO (1) NO307738B1 (zh)
NZ (1) NZ261740A (zh)
WO (1) WO1994019008A1 (zh)
ZA (1) ZA941036B (zh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2889014A1 (fr) 2005-07-22 2007-01-26 Nextamp Sa Procede et dispositif de tatouage d'horodates, procede et dispositif de decodage d'horodates, applications et produits programmes d'ordinateur correspondants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3526015A1 (de) * 1985-07-20 1987-01-22 Philips Patentverwaltung Verfahren zum bestimmen der raeumlichen verteilung der streuquerschnitte fuer elastisch gestreute roentgenstrahlung und anordnung zur durchfuehrung des verfahrens
US5004746A (en) * 1987-09-29 1991-04-02 Merrell Dow Pharmaceuticals Inc. Anti-retroviral castanospermine esters
US4999146A (en) * 1990-02-12 1991-03-12 Thermax Wire Corp. Process for manufacture of low density polytetrofluoroethylene insulated cable
ATE143025T1 (de) * 1991-01-02 1996-10-15 Merrell Pharma Inc Antivirale verbindungen

Also Published As

Publication number Publication date
CN1118142A (zh) 1996-03-06
IL108696A0 (en) 1994-05-30
NO307738B1 (no) 2000-05-22
ZA941036B (en) 1994-08-25
CA2155129A1 (en) 1994-09-01
KR960700743A (ko) 1996-02-24
AU6091894A (en) 1994-09-14
NO953272D0 (no) 1995-08-21
HUT72493A (en) 1996-05-28
AU679497B2 (en) 1997-07-03
EP0684836A1 (en) 1995-12-06
GB9303518D0 (en) 1993-04-07
KR100293299B1 (ko) 2001-09-17
MXPA94001311A (es) 2003-11-13
JPH08509469A (ja) 1996-10-08
HU9502451D0 (en) 1995-10-30
NZ261740A (en) 1996-10-28
IL108696A (en) 1999-06-20
NO953272L (no) 1995-08-21
WO1994019008A1 (en) 1994-09-01

Similar Documents

Publication Publication Date Title
JP3133345B2 (ja) Hivに対して活性な連結環状ポリアミン
EP1387681B1 (en) Use of castanospermine derivatives for the treatment of hepatitis c
WO2007053574A2 (en) Combinations comprising sorafenib and interferon for the treatment of cancer
JP2720169B2 (ja) 抗レトロウイルス活性をもつ糖タンパク処理抑制剤
SK99899A3 (en) Quinoxaline in triple combination with protease inhibitors and reverse transcriptase inhibitors as medicines for treating aids
EP0345751A1 (en) Anti-retroviral diflourinated nucleosides
US5939430A (en) Combinations of retroviral inhibitors
CA2155129C (en) Combinations of retroviral inhibitors
PL182742B1 (pl) Kombinacja związków do leczenia infekcji HIV i/lub AIDS, środek farmaceutyczny oraz zastosowanie kombinacji związków do wytwarzania leku do leczenia infekcji HIV i/lub AIDS
EP1670448B1 (en) Hcv inhibiting sulfonamides
TW393318B (en) Synergistic pharmaceutical composition for use in the treatment of retroviral infections
EP0543555A1 (en) Phosphorylated flavanoids in the treatment of viral diseases
EP0428105B1 (en) Use of quinolyl- and isoquinolyloxazole-2-ones for the production of a medicament for the prevention of glycoprotein enveloped virus infectivity
JPH02262516A (ja) グアニジノ安息香酸誘導体を有効成分として含有する抗レトロウイルス剤
EP0428103A2 (en) Prevention of glycoprotein enveloped virus infectivity by pyridyloxazole-2-ones
WO1995017875A2 (en) MIXTURES OF DIDEOXYNUCLEOSIDES AND D-ASPARTIC ACID β-HYDROXAMATE FOR INHIBITING RETROVIRAL SPREAD
ZA200309040B (en) HIV protease inhibitors, compositions containing the same, their pharmaceutical uses and materials for their synthesis.
JPH01180893A (ja) 5−アミノ−6炭糖を含有する抗ウイルス剤
JPH01172321A (ja) 6−0−置換−D−グルコ−δ−ラクタムを含有する抗ウイルス剤

Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKLA Lapsed

Effective date: 20060118