CA2154124C - Methodes et compositions pour le traitement des blessures - Google Patents
Methodes et compositions pour le traitement des blessures Download PDFInfo
- Publication number
- CA2154124C CA2154124C CA002154124A CA2154124A CA2154124C CA 2154124 C CA2154124 C CA 2154124C CA 002154124 A CA002154124 A CA 002154124A CA 2154124 A CA2154124 A CA 2154124A CA 2154124 C CA2154124 C CA 2154124C
- Authority
- CA
- Canada
- Prior art keywords
- polysaccharide
- composition
- cross
- linked
- oxidized
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
- A61L26/0023—Polysaccharides
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Materials Engineering (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Abstract
Des compositions de traitement des blessures comprennent un polysaccharide réticulé oxydé qui a une charge induite chimiquement. Les polysaccharides préférés sont des dextranes réticulés. Une charge est fournie de préférence par des groupes de diéthylaminoéthyle (groupes DEAE) ou des groupes de carboxyméthyle. Le polysaccharide réticulé oxydé peut être appliqué sous forme d'une poudre directement à un site de plaie. Dans un autre mode de réalisation, le polysaccharide réticulé oxydé peut être combiné avec un véhicule d'administration pour former un liquide ou appliqué à un site de blessure.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/278,778 US5502042A (en) | 1994-07-22 | 1994-07-22 | Methods and compositions for treating wounds |
US08/278,778 | 1994-07-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2154124A1 CA2154124A1 (fr) | 1996-01-23 |
CA2154124C true CA2154124C (fr) | 2010-01-12 |
Family
ID=23066328
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002154124A Expired - Lifetime CA2154124C (fr) | 1994-07-22 | 1995-07-18 | Methodes et compositions pour le traitement des blessures |
Country Status (4)
Country | Link |
---|---|
US (1) | US5502042A (fr) |
EP (1) | EP0693291B1 (fr) |
CA (1) | CA2154124C (fr) |
DE (1) | DE69524682T2 (fr) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998027117A1 (fr) * | 1996-12-18 | 1998-06-25 | Sca Hygiene Products Zeist B.V. | Matiere extremement absorbante et procede de production associe |
GB2320502B (en) * | 1996-12-20 | 2000-09-20 | Johnson & Johnson Medical | Bioresorbable alginate derivatives |
US6531154B1 (en) * | 1997-06-10 | 2003-03-11 | Brown University Research Foundation | Modulated release from biocompatible polymers |
US6440940B1 (en) | 1997-12-18 | 2002-08-27 | Peter J. Doyle | Bioresorbable alginate derivatives |
EP1731175B1 (fr) * | 1998-11-12 | 2009-09-30 | International Manufacturing Group, Inc. | Perles de dextrane réticulés hemostatiques permettant une coagulation sanguine rapide et l'hémostase |
US6060461A (en) * | 1999-02-08 | 2000-05-09 | Drake; James Franklin | Topically applied clotting material |
WO2000051566A1 (fr) * | 1999-03-04 | 2000-09-08 | United States Surgical Corporation | Procede d'attenuation de cicatrice |
WO2000056155A1 (fr) * | 1999-03-25 | 2000-09-28 | United States Surgical Corporation | Methode de promotion de l'angiogenese |
AU2002318023B2 (en) * | 2001-05-09 | 2007-01-04 | Biointeractions Ltd. | Wound closure system and methods |
AU2002361902A1 (en) | 2001-12-31 | 2003-07-24 | Ares Medical, Inc. | Hemostatic compositions and methods for controlling bleeding |
US20040220534A1 (en) * | 2003-04-29 | 2004-11-04 | Martens Paul W. | Medical device with antimicrobial layer |
US8034048B2 (en) * | 2003-05-05 | 2011-10-11 | Boston Scientific Scimed, Inc. | Tissue patches and related delivery systems and methods |
US7416546B2 (en) | 2003-05-05 | 2008-08-26 | Boston Scientific Scimed, Inc. | Tissue patches and related delivery systems and methods |
DE602004030264D1 (de) * | 2003-09-12 | 2011-01-05 | Z Medica Corp | Teilweise hydriertes hämostatisches mittel |
US7758654B2 (en) | 2004-05-20 | 2010-07-20 | Kensey Nash Corporation | Anti-adhesion device |
US8431114B2 (en) * | 2004-10-07 | 2013-04-30 | Actamax Surgical Materials, Llc | Polysaccharide-based polymer tissue adhesive for medical use |
US20060178609A1 (en) | 2005-02-09 | 2006-08-10 | Z-Medica, Llc | Devices and methods for the delivery of molecular sieve materials for the formation of blood clots |
KR20070117589A (ko) | 2005-02-15 | 2007-12-12 | 버지니아 커먼웰스 유니버시티 | 급성 지혈 및 급성 상처와 만성 궤양의 치료를 위한 광물기술 |
US9119901B2 (en) * | 2005-04-28 | 2015-09-01 | Warsaw Orthopedic, Inc. | Surface treatments for promoting selective tissue attachment to medical impants |
US8414907B2 (en) | 2005-04-28 | 2013-04-09 | Warsaw Orthopedic, Inc. | Coatings on medical implants to guide soft tissue healing |
US20070087061A1 (en) * | 2005-10-14 | 2007-04-19 | Medafor, Incorporated | Method and composition for creating and/or activating a platelet-rich gel by contact with a porous particulate material, for use in wound care, tissue adhesion, or as a matrix for delivery of therapeutic components |
US20070248653A1 (en) * | 2006-04-20 | 2007-10-25 | Cochrum Kent C | Hemostatic compositions and methods for controlling bleeding |
US8938898B2 (en) * | 2006-04-27 | 2015-01-27 | Z-Medica, Llc | Devices for the identification of medical products |
US7604819B2 (en) | 2006-05-26 | 2009-10-20 | Z-Medica Corporation | Clay-based hemostatic agents and devices for the delivery thereof |
US7968114B2 (en) | 2006-05-26 | 2011-06-28 | Z-Medica Corporation | Clay-based hemostatic agents and devices for the delivery thereof |
US8282959B2 (en) * | 2006-11-27 | 2012-10-09 | Actamax Surgical Materials, Llc | Branched end reactants and polymeric hydrogel tissue adhesives therefrom |
US20080317831A1 (en) * | 2007-06-21 | 2008-12-25 | Denny Lo | Hemostatic sponge and method of making the same |
US20090035249A1 (en) * | 2007-08-02 | 2009-02-05 | Bhatia Sujata K | Method of inhibiting proliferation of Escherichia coli |
WO2009064963A2 (fr) * | 2007-11-14 | 2009-05-22 | E. I. Du Pont De Nemours And Company | Adhésif tissulaire polymère à base de polysaccharide cationique oxydé, à usage médical |
US8551136B2 (en) | 2008-07-17 | 2013-10-08 | Actamax Surgical Materials, Llc | High swell, long-lived hydrogel sealant |
US20100015231A1 (en) * | 2008-07-17 | 2010-01-21 | E.I. Du Pont De Nemours And Company | Low swell, long-lived hydrogel sealant |
US8466327B2 (en) | 2008-11-19 | 2013-06-18 | Actamax Surgical Materials, Llc | Aldehyde-functionalized polyethers and method of making same |
EP2349357B1 (fr) * | 2008-11-19 | 2012-10-03 | Actamax Surgical Materials LLC | Adhésif de type hydrogel pour tissus formés à partir de polysaccharide aminé et de polyéther à plusieurs bras fonctionnalisé par aldéhyde |
US20100160960A1 (en) * | 2008-12-19 | 2010-06-24 | E. I. Du Pont De Nemours And Company | Hydrogel tissue adhesive having increased degradation time |
JP2012523289A (ja) | 2009-04-09 | 2012-10-04 | アクタマックス サージカル マテリアルズ リミテッド ライアビリティ カンパニー | 減少した分解時間を有するハイドロゲル組織接着剤 |
US8580950B2 (en) | 2009-07-02 | 2013-11-12 | Actamax Surgical Materials, Llc | Aldehyde-functionalized polysaccharides |
EP2448604B1 (fr) | 2009-07-02 | 2016-03-23 | Actamax Surgical Materials LLC | Adhesif de type hydrogel pour tissu a usage medical |
US8580951B2 (en) | 2009-07-02 | 2013-11-12 | Actamax Surgical Materials, Llc | Aldehyde-functionalized polysaccharides |
US8796242B2 (en) | 2009-07-02 | 2014-08-05 | Actamax Surgical Materials, Llc | Hydrogel tissue adhesive for medical use |
KR101003331B1 (ko) * | 2010-05-11 | 2010-12-23 | 조강선 | 피부 충전제 조성물 |
US20160145567A1 (en) * | 2010-05-27 | 2016-05-26 | Corning Incorporated | Cell culture article and methods thereof |
US8858969B2 (en) | 2010-09-22 | 2014-10-14 | Z-Medica, Llc | Hemostatic compositions, devices, and methods |
JP2012107033A (ja) * | 2012-02-02 | 2012-06-07 | Medafor Inc | 局所適用される凝血材料 |
CA2876850C (fr) | 2012-06-22 | 2023-02-21 | Z-Medica, Llc | Dispositifs hemostatiques |
US8859705B2 (en) | 2012-11-19 | 2014-10-14 | Actamax Surgical Materials Llc | Hydrogel tissue adhesive having decreased gelation time and decreased degradation time |
WO2015017340A2 (fr) | 2013-07-29 | 2015-02-05 | Actamax Surgical Materials, Llc | Adhésif pour tissu à faible gonflement et formulations d'obturant |
IL249725A0 (en) | 2016-12-22 | 2017-03-30 | Omrix Biopharmaceuticals Ltd | A hemostatic preparation containing an anion exchanger and a calcium salt |
JP2020502241A (ja) * | 2016-12-22 | 2020-01-23 | オムリックス・バイオファーマシューティカルズ・リミテッドOmrix Biopharmaceuticals Ltd. | アニオン交換体及びカルシウム塩を含む止血用組成物 |
EP3717028A1 (fr) * | 2017-11-28 | 2020-10-07 | Baxter International Inc | Absorbant pour le traitement des plaies |
US11739166B2 (en) | 2020-07-02 | 2023-08-29 | Davol Inc. | Reactive polysaccharide-based hemostatic agent |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2988455A (en) * | 1958-03-06 | 1961-06-13 | American Mach & Foundry | Polysaccharide composition and method of manufacture |
US3042667A (en) * | 1959-03-10 | 1962-07-03 | Pharmacia Ab | Process for producing dextran derivatives and products resulting therefrom |
DE1443396C3 (de) * | 1963-04-22 | 1975-01-23 | Aktiebolaget Pharmacia, Uppsala (Schweden) | Verfahren zur Herstellung von hochmolekularen, ionenaustauschende Gruppen enthaltenden, hydrophilen Vernetzungsprodukten |
FR2403098A1 (fr) * | 1977-09-19 | 1979-04-13 | Merieux Inst | Nouveau materiau capable de fixer de facon reversible des macromolecules biologiques, sa preparation et son application |
FR2403081A1 (fr) * | 1977-09-19 | 1979-04-13 | Merieux Inst | Nouveau materiau particulaire, sa preparation et son application, notamment comme medicament |
JPS55130909A (en) * | 1979-03-31 | 1980-10-11 | Agency Of Ind Science & Technol | Granular material containing active substance and having inactive surface-protecting layer, and its preparation |
US4370476A (en) * | 1979-07-17 | 1983-01-25 | Usher Thomas C | Dextran polycarboxylic acids, ferric hydroxide complexes |
US4624868A (en) * | 1979-12-17 | 1986-11-25 | Colgate-Palmolive Company | Borated polysaccharide absorbents and absorbent products |
SE8103137L (sv) * | 1981-05-19 | 1982-11-20 | Pharmacia Ab | Polymer med kvartera aminogrupper |
SE452469B (sv) * | 1986-06-18 | 1987-11-30 | Pharmacia Ab | Material bestaende av en tverbunden karboxylgrupphaltig polysackarid och forfarande vid framstellning av detsamma |
US4988358A (en) * | 1988-12-28 | 1991-01-29 | Eppley Barry L | Method for promoting hard tissue growth and repair in mammals |
US5092883A (en) * | 1988-12-28 | 1992-03-03 | Eppley Barry L | Method for promoting soft connective tissue growth and repair in mammals |
DE3903672C1 (fr) * | 1989-02-08 | 1990-02-01 | Lohmann Gmbh & Co Kg | |
EP0610441A4 (fr) | 1991-10-29 | 1996-01-10 | Clover Cons Ltd | Polysaccharides, polycations et lipides reticulables destines a l'encapsulation et la liberation de medicaments. |
GB9206504D0 (en) * | 1992-03-25 | 1992-05-06 | Jevco Ltd | Heteromorphic sponges as wound implants |
GB9206509D0 (en) * | 1992-03-25 | 1992-05-06 | Jevco Ltd | Heteromorphic sponges containing active agents |
US5344455A (en) * | 1992-10-30 | 1994-09-06 | Medtronic, Inc. | Graft polymer articles having bioactive surfaces |
-
1994
- 1994-07-22 US US08/278,778 patent/US5502042A/en not_active Expired - Lifetime
-
1995
- 1995-07-18 CA CA002154124A patent/CA2154124C/fr not_active Expired - Lifetime
- 1995-07-21 EP EP95111523A patent/EP0693291B1/fr not_active Expired - Lifetime
- 1995-07-21 DE DE69524682T patent/DE69524682T2/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0693291A3 (fr) | 1999-09-15 |
EP0693291A2 (fr) | 1996-01-24 |
DE69524682D1 (de) | 2002-01-31 |
US5502042A (en) | 1996-03-26 |
EP0693291B1 (fr) | 2001-12-19 |
DE69524682T2 (de) | 2002-08-14 |
CA2154124A1 (fr) | 1996-01-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2154124C (fr) | Methodes et compositions pour le traitement des blessures | |
US6756518B2 (en) | Scar reduction | |
US4570629A (en) | Hydrophilic biopolymeric copolyelectrolytes, and biodegradable wound dressing comprising same | |
KR101610268B1 (ko) | 외과용 하이드로겔 | |
US5116824A (en) | Biomaterial comprising a composite material of a chitosan derivative and collagen derivative | |
EP0356060B1 (fr) | Composition pour remplir des blessures | |
US6458380B1 (en) | Dressing and preparation delivery system | |
US6635272B2 (en) | Wound dressing and drug delivery system | |
JP2617260B2 (ja) | 創傷治療用ゲル配合物 | |
KR20040047537A (ko) | 알데히드 개질된 폴리사카라이드를 함유하는 지혈용 상처드레싱 | |
EP1152013A1 (fr) | Derive fonctionnel du chitosane | |
WO2000049084A1 (fr) | Composition gelifiee a base d'acide hyaluronique, procede de production associe et matiere medicale contenant ladite composition | |
JP2004174223A (ja) | アルデヒド変性した多糖類および止血物質を含有している止血用の傷用包帯 | |
KR20030086254A (ko) | 콜라겐 스펀지의 제조 방법, 콜라겐 발포체 부분의 추출장치, 및 신장된 콜라겐 스펀지 | |
CA2572297A1 (fr) | Hydrogels non adhesifs | |
EP1494728B1 (fr) | Pansements pour anomalie tissulaire comprenant des reseaux proteiques | |
KR100395723B1 (ko) | 항부착제 | |
KR20160060519A (ko) | 창상치료용 알긴산 하이드로젤 및 그 제조방법 | |
JP2004174221A (ja) | アルデヒド変性した再生多糖類を含有する傷用包帯 | |
CN112007201B (zh) | 一种可粘附抗菌止血海绵及其制备方法 | |
KR20020011955A (ko) | 유착방지제 | |
GB2322864A (en) | Gel for application to the human or animal body | |
CN112957519A (zh) | 用于制备促进创口愈合的水凝胶的组合物、水凝胶及其制备方法 | |
US20040235791A1 (en) | Scar reduction | |
JPH04139131A (ja) | 散布剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKEX | Expiry |
Effective date: 20150720 |
|
MKEX | Expiry |
Effective date: 20150720 |