CA2114468A1 - Ellipticine derivative and process for preparing the same - Google Patents

Ellipticine derivative and process for preparing the same

Info

Publication number
CA2114468A1
CA2114468A1 CA002114468A CA2114468A CA2114468A1 CA 2114468 A1 CA2114468 A1 CA 2114468A1 CA 002114468 A CA002114468 A CA 002114468A CA 2114468 A CA2114468 A CA 2114468A CA 2114468 A1 CA2114468 A1 CA 2114468A1
Authority
CA
Canada
Prior art keywords
group
substituted
protected
lower alkoxy
unprotected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002114468A
Other languages
English (en)
French (fr)
Inventor
Kenji Tsuhihara
Naoyuki Harada
Kinihiko Ozaki
Motoaki Ohashi
Koji Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of CA2114468A1 publication Critical patent/CA2114468A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA002114468A 1993-01-29 1994-01-28 Ellipticine derivative and process for preparing the same Abandoned CA2114468A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13441/1993 1993-01-29
JP1344193 1993-01-29

Publications (1)

Publication Number Publication Date
CA2114468A1 true CA2114468A1 (en) 1994-07-30

Family

ID=11833224

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002114468A Abandoned CA2114468A1 (en) 1993-01-29 1994-01-28 Ellipticine derivative and process for preparing the same

Country Status (11)

Country Link
US (2) US5565569A (OSRAM)
EP (1) EP0608876A1 (OSRAM)
KR (1) KR940018385A (OSRAM)
CN (1) CN1042731C (OSRAM)
AU (1) AU666416B2 (OSRAM)
CA (1) CA2114468A1 (OSRAM)
FI (1) FI940403L (OSRAM)
IL (1) IL108461A (OSRAM)
MY (1) MY110683A (OSRAM)
SG (1) SG42916A1 (OSRAM)
TW (1) TW269688B (OSRAM)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2696465B1 (fr) * 1992-10-02 1994-12-23 Adir Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2757859B1 (fr) * 1996-12-30 1999-01-29 Adir Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2757858B1 (fr) * 1996-12-30 1999-01-29 Adir Nouveaux derives d'ellipticine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6512102B1 (en) * 1998-12-31 2003-01-28 Chiron Corporation Compositions and methods of diagnosis and treatment using casein kinase I
US7847109B2 (en) * 2002-05-31 2010-12-07 Pharmagenesis, Inc. Triptolide derivatives for modulation of apoptosis and immunosuppression
US20090215800A1 (en) * 2005-05-05 2009-08-27 Chroma Therapeutics Ltd Enzyme and Receptor Modulation
FR2925491B1 (fr) * 2007-12-19 2010-09-03 Oz Biosciences Sas Nouvelle classe de lipides cationiques pour le transport d'agents actifs dans les cellules
US20150119388A1 (en) * 2012-06-15 2015-04-30 The Children's Hospital Philadelphia Novel pro- and codrug derivatives for nanoparticle delivery of select anticancer agents formed using rapidly cleavable phenolic ester bridges

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3933827A (en) * 1974-10-29 1976-01-20 Hoffmann-La Roche Inc. 9-Acyloxy-5,11-dimethyl-6H-pyrido[4,3-B]carbazoles
FR2308365A2 (fr) * 1975-04-25 1976-11-19 Anvar Derives de l'hydroxy-9 ellipticine et leur application therapeutique
US4310667A (en) * 1976-04-22 1982-01-12 Agence Nationale De Valorisation De La Recherche (Anvar) 2-N Quaternary ammonium salt derivatives of 9-hydroxy ellipticine
JPS6137799A (ja) * 1984-07-31 1986-02-22 Suntory Ltd エリプチシン誘導体およびその製造法
AU4245689A (en) * 1988-10-04 1990-04-12 Suntory Limited Ellipticine glycoside derivatives
JPH05310736A (ja) * 1992-05-06 1993-11-22 Tanabe Seiyaku Co Ltd エリプティシン誘導体、その製法およびその合成中間体
US5272146A (en) * 1992-10-02 1993-12-21 The United States Of America As Represented By The United States Department Of Health And Human Services 1,2-dihydroellipticines with activity against CNS specific cancer cell lines
FR2696465B1 (fr) * 1992-10-02 1994-12-23 Adir Nouveaux dérivés d'ellipticine, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
AU5394794A (en) 1994-08-04
FI940403A0 (fi) 1994-01-27
US5565569A (en) 1996-10-15
KR940018385A (ko) 1994-08-16
AU666416B2 (en) 1996-02-08
CN1099034A (zh) 1995-02-22
CN1042731C (zh) 1999-03-31
FI940403A7 (fi) 1994-07-30
EP0608876A1 (en) 1994-08-03
FI940403L (fi) 1994-07-30
MY110683A (en) 1999-01-30
SG42916A1 (en) 1997-10-17
TW269688B (OSRAM) 1996-02-01
IL108461A (en) 1998-09-24
US5605904A (en) 1997-02-25
IL108461A0 (en) 1994-04-12

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued