CA2110992A1 - Procede de production de proteines recombinantes et cellules hotes utilisees - Google Patents
Procede de production de proteines recombinantes et cellules hotes utiliseesInfo
- Publication number
- CA2110992A1 CA2110992A1 CA002110992A CA2110992A CA2110992A1 CA 2110992 A1 CA2110992 A1 CA 2110992A1 CA 002110992 A CA002110992 A CA 002110992A CA 2110992 A CA2110992 A CA 2110992A CA 2110992 A1 CA2110992 A1 CA 2110992A1
- Authority
- CA
- Canada
- Prior art keywords
- host cell
- protein
- cell according
- yeast
- plasmid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- 230000000869 mutational effect Effects 0.000 description 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 239000003016 pheromone Substances 0.000 description 1
- 229920002401 polyacrylamide Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 230000001124 posttranscriptional effect Effects 0.000 description 1
- 230000001323 posttranslational effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 230000003248 secreting effect Effects 0.000 description 1
- 238000012163 sequencing technique Methods 0.000 description 1
- 230000035939 shock Effects 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 239000000892 thaumatin Substances 0.000 description 1
- 235000010436 thaumatin Nutrition 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 230000005026 transcription initiation Effects 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 1
- 229940045145 uridine Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9108217 | 1991-07-02 | ||
| FR9108217A FR2678636A1 (fr) | 1991-07-02 | 1991-07-02 | Procede de production de proteines recombinantes et cellules hote utilisees. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2110992A1 true CA2110992A1 (fr) | 1993-01-21 |
Family
ID=9414582
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002110992A Abandoned CA2110992A1 (fr) | 1991-07-02 | 1992-06-30 | Procede de production de proteines recombinantes et cellules hotes utilisees |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP0521767A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JPH06509226A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE250126T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2278392A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2110992A1 (cg-RX-API-DMAC7.html) |
| DE (1) | DE69233206T2 (cg-RX-API-DMAC7.html) |
| DK (1) | DK0592574T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2203611T3 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2678636A1 (cg-RX-API-DMAC7.html) |
| IE (1) | IE922148A1 (cg-RX-API-DMAC7.html) |
| NO (1) | NO934572L (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ243403A (cg-RX-API-DMAC7.html) |
| PT (1) | PT592574E (cg-RX-API-DMAC7.html) |
| WO (1) | WO1993001274A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105063080A (zh) * | 2015-09-07 | 2015-11-18 | 复旦大学 | 不含有信号肽的在马克斯克鲁维酵母营养缺陷型菌株中进行外源基因表达的重组载体 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3381090D1 (de) * | 1982-05-19 | 1990-02-15 | Gist Brocades Nv | Klonierungssystem fuer kluyveromyce spezies. |
| IT1203758B (it) * | 1986-03-27 | 1989-02-23 | Univ Roma | Vettori di clonazione e di espressione di geni eterologhi in lieviti e lieviti trasformati con tali vettori |
| AU628018B2 (en) * | 1987-07-28 | 1992-09-10 | Dsm Ip Assets B.V. | Kluyveromyces as a host strain |
| FR2649991B2 (fr) * | 1988-08-05 | 1994-03-04 | Rhone Poulenc Sante | Utilisation de derives stables du plasmide pkd1 pour l'expression et la secretion de proteines heterologues dans les levures du genre kluyveromyces |
-
1991
- 1991-07-02 FR FR9108217A patent/FR2678636A1/fr active Granted
-
1992
- 1992-06-30 PT PT92915114T patent/PT592574E/pt unknown
- 1992-06-30 EP EP92401848A patent/EP0521767A1/fr active Pending
- 1992-06-30 EP EP92915114A patent/EP0592574B1/fr not_active Expired - Lifetime
- 1992-06-30 ES ES92915114T patent/ES2203611T3/es not_active Expired - Lifetime
- 1992-06-30 JP JP5502002A patent/JPH06509226A/ja active Pending
- 1992-06-30 CA CA002110992A patent/CA2110992A1/fr not_active Abandoned
- 1992-06-30 DE DE69233206T patent/DE69233206T2/de not_active Expired - Lifetime
- 1992-06-30 DK DK92915114T patent/DK0592574T3/da active
- 1992-06-30 AT AT92915114T patent/ATE250126T1/de active
- 1992-06-30 WO PCT/FR1992/000610 patent/WO1993001274A1/fr not_active Ceased
- 1992-06-30 AU AU22783/92A patent/AU2278392A/en not_active Abandoned
- 1992-07-01 NZ NZ243403A patent/NZ243403A/en unknown
- 1992-07-01 IE IE214892A patent/IE922148A1/en not_active Application Discontinuation
-
1993
- 1993-12-13 NO NO934572A patent/NO934572L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT592574E (pt) | 2004-02-27 |
| NO934572D0 (no) | 1993-12-13 |
| DE69233206D1 (de) | 2003-10-23 |
| JPH06509226A (ja) | 1994-10-20 |
| FR2678636B1 (cg-RX-API-DMAC7.html) | 1994-08-19 |
| NO934572L (no) | 1993-12-13 |
| ES2203611T3 (es) | 2004-04-16 |
| NZ243403A (en) | 1994-12-22 |
| EP0592574B1 (fr) | 2003-09-17 |
| EP0521767A1 (fr) | 1993-01-07 |
| DK0592574T3 (da) | 2004-01-19 |
| EP0592574A1 (fr) | 1994-04-20 |
| ATE250126T1 (de) | 2003-10-15 |
| DE69233206T2 (de) | 2004-07-01 |
| FR2678636A1 (fr) | 1993-01-08 |
| AU2278392A (en) | 1993-02-11 |
| WO1993001274A1 (fr) | 1993-01-21 |
| IE922148A1 (en) | 1993-01-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |