CA2103906C - Iloprost with action against cerebral malaria - Google Patents

Iloprost with action against cerebral malaria Download PDF

Info

Publication number
CA2103906C
CA2103906C CA002103906A CA2103906A CA2103906C CA 2103906 C CA2103906 C CA 2103906C CA 002103906 A CA002103906 A CA 002103906A CA 2103906 A CA2103906 A CA 2103906A CA 2103906 C CA2103906 C CA 2103906C
Authority
CA
Canada
Prior art keywords
iloprost
cerebral malaria
use according
medicament
tnf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA002103906A
Other languages
English (en)
French (fr)
Other versions
CA2103906A1 (en
Inventor
Eveline Blitstein-Willinger
Karin Sliwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of CA2103906A1 publication Critical patent/CA2103906A1/en
Application granted granted Critical
Publication of CA2103906C publication Critical patent/CA2103906C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002103906A 1991-02-12 1992-02-07 Iloprost with action against cerebral malaria Expired - Fee Related CA2103906C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4104606.4 1991-02-12
DE4104606A DE4104606C1 (enExample) 1991-02-12 1991-02-12
PCT/DE1992/000091 WO1992013537A1 (de) 1991-02-12 1992-02-07 Iloprost mit wirkung gegen cerebrale malaria

Publications (2)

Publication Number Publication Date
CA2103906A1 CA2103906A1 (en) 1992-08-13
CA2103906C true CA2103906C (en) 2003-06-03

Family

ID=6425074

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002103906A Expired - Fee Related CA2103906C (en) 1991-02-12 1992-02-07 Iloprost with action against cerebral malaria

Country Status (12)

Country Link
US (1) US5466713A (enExample)
EP (1) EP0571457B1 (enExample)
JP (1) JP3322311B2 (enExample)
KR (1) KR100188164B1 (enExample)
AT (1) ATE147628T1 (enExample)
AU (1) AU663484B2 (enExample)
CA (1) CA2103906C (enExample)
DE (2) DE4104606C1 (enExample)
DK (1) DK0571457T3 (enExample)
ES (1) ES2099247T3 (enExample)
GR (1) GR3022870T3 (enExample)
WO (1) WO1992013537A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4124695C2 (de) * 1991-07-22 1994-12-22 Blitstein Willinger Eveline Dr Verwendung von Carbacyclinderivaten zur Behandlung von Psoriasis vulgaris
DE4226615C1 (de) * 1992-08-07 1994-05-19 Schering Ag Verwendung von Prostan-Derivaten zur Behandlung von chronischer Polyarthritis
JP2006517576A (ja) * 2003-02-14 2006-07-27 メディカル リサーチ カウンシル 病理的子宮症状の治療のためのｉｐレセプターアンタゴニスト
CA2959852A1 (en) 2003-05-22 2005-01-27 United Therapeutics Corporation Compounds and methods for delivery of prostacyclin analogs
US8747897B2 (en) 2006-04-27 2014-06-10 Supernus Pharmaceuticals, Inc. Osmotic drug delivery system
CN101903324B (zh) 2007-12-17 2013-07-03 联合治疗公司 一种制备Remodulin中的活性成分曲前列素的改良方法
IN2014DN06981A (enExample) * 2012-02-02 2015-04-10 Becton Dickinson Co
JP2016517410A (ja) 2013-03-14 2016-06-16 ユナイテッド セラピューティクス コーポレイション トレプロスチニルの固体形態
JP6224872B1 (ja) 2014-10-20 2017-11-01 ユナイテッド セラピューティクス コーポレイション プロスタサイクリン誘導体を生成するための中間体の合成

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2845770A1 (de) * 1978-10-19 1980-04-30 Schering Ag Neue prostacyclin-derivate und verfahren zu ihrer herstellung
DE3121155A1 (de) * 1981-05-22 1982-12-09 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE3608088C2 (de) * 1986-03-07 1995-11-16 Schering Ag Pharmazeutische Präparate, enthaltend Cyclodextrinclathrate von Carbacyclinderivaten

Also Published As

Publication number Publication date
JP3322311B2 (ja) 2002-09-09
DE4104606C1 (enExample) 1992-10-15
AU1237592A (en) 1992-09-07
ES2099247T3 (es) 1997-05-16
US5466713A (en) 1995-11-14
DK0571457T3 (da) 1997-07-14
GR3022870T3 (en) 1997-06-30
CA2103906A1 (en) 1992-08-13
KR100188164B1 (en) 1999-06-01
JPH06507380A (ja) 1994-08-25
EP0571457A1 (de) 1993-12-01
WO1992013537A1 (de) 1992-08-20
AU663484B2 (en) 1995-10-12
DE59207900D1 (de) 1997-02-27
EP0571457B1 (de) 1997-01-15
ATE147628T1 (de) 1997-02-15

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed