CA2084180A1 - Expression of specific immunogens using viral antigens - Google Patents
Expression of specific immunogens using viral antigensInfo
- Publication number
- CA2084180A1 CA2084180A1 CA002084180A CA2084180A CA2084180A1 CA 2084180 A1 CA2084180 A1 CA 2084180A1 CA 002084180 A CA002084180 A CA 002084180A CA 2084180 A CA2084180 A CA 2084180A CA 2084180 A1 CA2084180 A1 CA 2084180A1
- Authority
- CA
- Canada
- Prior art keywords
- epitopes
- protein
- site
- epitope
- vaccine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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Classifications
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
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- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
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- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Communicable Diseases (AREA)
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- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Immunology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80510591A | 1991-12-11 | 1991-12-11 | |
| US07/805,105 | 1991-12-11 |
Publications (1)
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|---|---|
| CA2084180A1 true CA2084180A1 (en) | 1993-06-12 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA002084180A Abandoned CA2084180A1 (en) | 1991-12-11 | 1992-11-30 | Expression of specific immunogens using viral antigens |
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| EP (1) | EP0546787A3 (enExample) |
| JP (1) | JPH05262667A (enExample) |
| KR (1) | KR930013112A (enExample) |
| CN (1) | CN1073878A (enExample) |
| AU (1) | AU2981992A (enExample) |
| BR (1) | BR9204978A (enExample) |
| CA (1) | CA2084180A1 (enExample) |
| CZ (1) | CZ362692A3 (enExample) |
| FI (1) | FI925590A7 (enExample) |
| HU (2) | HUT65366A (enExample) |
| IL (1) | IL103928A0 (enExample) |
| MX (1) | MX9207113A (enExample) |
| NO (1) | NO924780L (enExample) |
| SK (1) | SK362692A3 (enExample) |
| TW (1) | TW239162B (enExample) |
| ZA (1) | ZA929355B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| PT633929E (pt) * | 1992-04-01 | 2004-07-30 | Merix Bioscience Inc | Metodo para proliferacao (in vitro) de precursores de celulas dentifricas e sua utilizacao para produzir imunogenios |
| EP0671926B1 (en) * | 1992-08-11 | 2002-11-13 | President And Fellows Of Harvard College | Immunomodulatory peptides |
| WO1995007099A1 (en) * | 1993-09-09 | 1995-03-16 | The Nisshin Oil Mills, Ltd. | Vaccine and process for producing the same |
| US5762939A (en) * | 1993-09-13 | 1998-06-09 | Mg-Pmc, Llc | Method for producing influenza hemagglutinin multivalent vaccines using baculovirus |
| EP2374894B1 (en) * | 1993-09-13 | 2014-09-17 | Protein Sciences Corporation | A method for producing influenza hemagglutinin multivalent vaccines |
| ES2370937T3 (es) | 1993-09-13 | 2011-12-23 | Protein Sciences Corporation | Un método para producir vacunas antigripales polivalentes a base de hemaglutinina. |
| US6300090B1 (en) | 1994-07-29 | 2001-10-09 | The Rockefeller University | Methods of use of viral vectors to deliver antigen to dendritic cells |
| PT1275726E (pt) * | 1995-05-26 | 2008-05-16 | Protein Sciences Corp | Método para produzir vacinas multivalentes de hemaglutinina de influenza |
| US7659119B2 (en) | 1996-02-12 | 2010-02-09 | Argos Therapeutics, Inc. | Method and compositions for obtaining mature dendritic cells |
| WO1998048834A1 (en) * | 1997-04-30 | 1998-11-05 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant influenza viruses expressing tumor-associated antigens as antitumor agents |
| ATE428769T1 (de) | 1997-10-27 | 2009-05-15 | Univ Rockefeller | Methode und zusammensetzung zur herstellung von reifen dendritischen zellen |
| WO1999042564A2 (en) | 1998-02-20 | 1999-08-26 | The Rockefeller University | Apoptotic cell-mediated antigen presentation to dendritic cells |
| WO2002026252A1 (en) * | 2000-08-10 | 2002-04-04 | Tsinghua University | A vaccine for influenza virus and its preparation |
| BR0114126A (pt) | 2000-09-11 | 2003-08-26 | Dow Global Technologies Inc | Reforço de pneu para rodar vazio e método de fabricação |
| WO2004091491A2 (en) * | 2003-04-10 | 2004-10-28 | Transform Pharmaceuticals, Inc. | Profiling conformational variants, antibody compositions and methods of using the same |
| KR20080027777A (ko) * | 2005-06-01 | 2008-03-28 | 배리에이션 바이오테크놀로지스 아이엔씨. | 펩티드기초 인플루엔자 백신 제제 |
| CA2637600A1 (en) | 2006-01-17 | 2007-07-26 | Health Research, Inc. | Heteroduplex tracking assay |
| TWI494319B (zh) * | 2007-02-21 | 2015-08-01 | Oncotherapy Science Inc | 表現腫瘤相關抗原之癌症的胜肽疫苗 |
| EP2012122A1 (en) * | 2007-07-06 | 2009-01-07 | Medigene AG | Mutated parvovirus structural proteins as vaccines |
| CA2697373C (en) * | 2007-08-27 | 2019-05-21 | Longhorn Vaccines & Diagnostics, Llc | Immunogenic compositions and methods |
| US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| TW201008574A (en) | 2008-08-19 | 2010-03-01 | Oncotherapy Science Inc | INHBB epitope peptides and vaccines containing the same |
| MX2011004176A (es) | 2008-10-22 | 2011-09-21 | Oncotherapy Science Inc | Peptido-epitope rab6kifl/kif20a y vacunas que contienen el mismo. |
| CN101708442B (zh) * | 2009-09-04 | 2011-08-24 | 山东中惠仪器有限公司 | 全自动标准气体配制装置 |
| WO2011119920A2 (en) | 2010-03-25 | 2011-09-29 | Oregon Health & Science University | Cmv glycoproteins and recombinant vectors |
| ES2667425T3 (es) | 2011-06-10 | 2018-05-10 | Oregon Health & Science University | Glucoproteínas y vectores recombinantes de CMV |
| AU2012216792A1 (en) | 2011-09-12 | 2013-03-28 | International Aids Vaccine Initiative | Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies |
| EP2586461A1 (en) | 2011-10-27 | 2013-05-01 | Christopher L. Parks | Viral particles derived from an enveloped virus |
| EP2679596B1 (en) | 2012-06-27 | 2017-04-12 | International Aids Vaccine Initiative | HIV-1 env glycoprotein variant |
| US20150065381A1 (en) | 2013-09-05 | 2015-03-05 | International Aids Vaccine Initiative | Methods of identifying novel hiv-1 immunogens |
| EP2873423B1 (en) | 2013-10-07 | 2017-05-31 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| US10174292B2 (en) | 2015-03-20 | 2019-01-08 | International Aids Vaccine Initiative | Soluble HIV-1 envelope glycoprotein trimers |
| EP3072901A1 (en) | 2015-03-23 | 2016-09-28 | International Aids Vaccine Initiative | Soluble hiv-1 envelope glycoprotein trimers |
| SG10202108573TA (en) * | 2016-02-03 | 2021-09-29 | Cg Discovery Inc | Compositions of influenza hemagglutinin with heterologous epitopes and/or altered maturation cleavage sites |
| US10063211B2 (en) | 2016-02-03 | 2018-08-28 | Qualcomm Incorporated | Compact bypass and decoupling structure for millimeter-wave circuits |
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| EP0339504A3 (en) * | 1988-04-26 | 1990-09-12 | The Du Pont Merck Pharmaceutical Company | Human immunodeficiency virus (hiv) env-coded peptide capable of eliciting hiv-inhibiting antibodies in mammals |
| US5166057A (en) * | 1989-08-28 | 1992-11-24 | The Mount Sinai School Of Medicine Of The City University Of New York | Recombinant negative strand rna virus expression-systems |
| EP0492920A1 (en) * | 1990-12-24 | 1992-07-01 | Merck & Co. Inc. | Chimaeric influenza-HIV vaccine |
-
1992
- 1992-11-30 IL IL103928A patent/IL103928A0/xx unknown
- 1992-11-30 CA CA002084180A patent/CA2084180A1/en not_active Abandoned
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- 1992-12-02 ZA ZA929355A patent/ZA929355B/xx unknown
- 1992-12-02 AU AU29819/92A patent/AU2981992A/en not_active Abandoned
- 1992-12-07 TW TW081109778A patent/TW239162B/zh active
- 1992-12-07 EP EP19920311146 patent/EP0546787A3/en not_active Withdrawn
- 1992-12-09 KR KR1019920023656A patent/KR930013112A/ko not_active Withdrawn
- 1992-12-09 FI FI925590A patent/FI925590A7/fi not_active Application Discontinuation
- 1992-12-09 MX MX9207113A patent/MX9207113A/es unknown
- 1992-12-10 CN CN92113703A patent/CN1073878A/zh active Pending
- 1992-12-10 SK SK3626-92A patent/SK362692A3/sk unknown
- 1992-12-10 BR BR9204978A patent/BR9204978A/pt not_active Application Discontinuation
- 1992-12-10 CZ CS923626A patent/CZ362692A3/cs unknown
- 1992-12-10 NO NO92924780A patent/NO924780L/no unknown
- 1992-12-11 HU HU9203931A patent/HUT65366A/hu unknown
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1993
- 1993-12-17 US US08/169,813 patent/US5591823A/en not_active Expired - Lifetime
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1995
- 1995-06-27 HU HU95P/P00456P patent/HU211548A9/hu unknown
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| JPH05262667A (ja) | 1993-10-12 |
| FI925590L (fi) | 1993-06-12 |
| EP0546787A2 (en) | 1993-06-16 |
| CZ362692A3 (en) | 1994-02-16 |
| SK362692A3 (en) | 1995-11-08 |
| CN1073878A (zh) | 1993-07-07 |
| IL103928A0 (en) | 1993-04-04 |
| BR9204978A (pt) | 1993-06-15 |
| HUT65366A (en) | 1994-05-02 |
| TW239162B (enExample) | 1995-01-21 |
| HU9203931D0 (en) | 1993-04-28 |
| NO924780D0 (no) | 1992-12-10 |
| AU2981992A (en) | 1993-06-17 |
| FI925590A0 (fi) | 1992-12-09 |
| NO924780L (no) | 1993-06-14 |
| ZA929355B (en) | 1994-06-02 |
| MX9207113A (es) | 1994-05-31 |
| US5591823A (en) | 1997-01-07 |
| HU211548A9 (en) | 1995-12-28 |
| EP0546787A3 (en) | 1994-06-01 |
| FI925590A7 (fi) | 1993-06-12 |
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