CA2075982A1 - Insulin compositions - Google Patents

Insulin compositions

Info

Publication number
CA2075982A1
CA2075982A1 CA002075982A CA2075982A CA2075982A1 CA 2075982 A1 CA2075982 A1 CA 2075982A1 CA 002075982 A CA002075982 A CA 002075982A CA 2075982 A CA2075982 A CA 2075982A CA 2075982 A1 CA2075982 A1 CA 2075982A1
Authority
CA
Canada
Prior art keywords
insulin
iii
ins
general formula
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002075982A
Other languages
English (en)
French (fr)
Inventor
Jorgen F. Hansen
Ulla Ribel-Madsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2075982A1 publication Critical patent/CA2075982A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CA002075982A 1990-02-21 1991-02-21 Insulin compositions Abandoned CA2075982A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK045590A DK45590D0 (US07223432-20070529-C00017.png) 1990-02-21 1990-02-21
DK0455/90 1990-02-21

Publications (1)

Publication Number Publication Date
CA2075982A1 true CA2075982A1 (en) 1991-08-22

Family

ID=8093754

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002075982A Abandoned CA2075982A1 (en) 1990-02-21 1991-02-21 Insulin compositions

Country Status (12)

Country Link
EP (1) EP0516704B1 (US07223432-20070529-C00017.png)
JP (1) JPH05503940A (US07223432-20070529-C00017.png)
AU (1) AU641991B2 (US07223432-20070529-C00017.png)
CA (1) CA2075982A1 (US07223432-20070529-C00017.png)
DE (1) DE69100626D1 (US07223432-20070529-C00017.png)
DK (1) DK45590D0 (US07223432-20070529-C00017.png)
HU (1) HUT63858A (US07223432-20070529-C00017.png)
IE (1) IE910579A1 (US07223432-20070529-C00017.png)
NZ (1) NZ237176A (US07223432-20070529-C00017.png)
PT (1) PT96841A (US07223432-20070529-C00017.png)
WO (1) WO1991012817A1 (US07223432-20070529-C00017.png)
ZA (1) ZA911279B (US07223432-20070529-C00017.png)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9316895D0 (en) * 1993-08-13 1993-09-29 Guy S And St Thomas Hospitals Hepatoselective insulin analogues
US6342225B1 (en) 1993-08-13 2002-01-29 Deutshces Wollforschungsinstitut Pharmaceutical active conjugates
US6011007A (en) * 1993-09-17 2000-01-04 Novo Nordisk A/S Acylated insulin
US6869930B1 (en) 1993-09-17 2005-03-22 Novo Nordisk A/S Acylated insulin
US6251856B1 (en) 1995-03-17 2001-06-26 Novo Nordisk A/S Insulin derivatives
US6451762B1 (en) 1997-10-24 2002-09-17 Novo Nordisk A/S Aggregates of human insulin derivatives
WO2005012347A2 (en) 2003-08-05 2005-02-10 Novo Nordisk A/S Novel insulin derivatives
RU2352581C2 (ru) 2003-08-05 2009-04-20 Ново Нордиск А/С Производные инсулина
ES2438145T3 (es) 2005-02-02 2014-01-16 Novo Nordisk A/S Nuevos derivados de insulina
EP2505593A1 (en) 2005-12-28 2012-10-03 Novo Nordisk A/S Compositions comprising an acylated insulin and zinc and method of making the said compositions
CN101573133B (zh) 2006-07-31 2014-08-27 诺沃-诺迪斯克有限公司 Peg化延长的胰岛素
BRPI0717098B8 (pt) 2006-09-22 2021-05-25 Novo Nordisk As análogos de insulina humana resistentes à protease, composição farmacêutica e processo para sua preparação
EP2502618A3 (en) 2007-04-30 2012-10-03 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
CN101677947B (zh) 2007-06-13 2013-07-17 诺沃-诺迪斯克有限公司 包含胰岛素衍生物的药物制剂
CN101970477B (zh) 2008-03-14 2014-12-31 诺沃-诺迪斯克有限公司 蛋白酶稳定的胰岛素类似物
KR20110004366A (ko) 2008-03-18 2011-01-13 노보 노르디스크 에이/에스 프로테아제 안정화되고, 아실화된 인슐린 유사체
US9603904B2 (en) 2008-10-30 2017-03-28 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
JP6049625B2 (ja) 2010-10-27 2016-12-21 ノヴォ ノルディスク アー／エス 様々な注射間隔を用いて施されるインスリン注射を使用する、真性糖尿病の治療
ES2594303T3 (es) 2012-04-11 2016-12-19 Novo Nordisk A/S Formulaciones de insulina
US10137172B2 (en) 2013-04-30 2018-11-27 Novo Nordisk A/S Administration regime
US9896496B2 (en) 2013-10-07 2018-02-20 Novo Nordisk A/S Derivative of an insulin analogue
CN115154591B (zh) 2016-12-16 2023-04-14 诺和诺德股份有限公司 含胰岛素的药物组合物
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE971500C (de) * 1950-11-22 1959-02-05 Organon Nv Verfahren zur Herstellung von Insulin-Suspensionen mit verlaengerter Wirkung
DE1107374B (de) * 1958-01-31 1961-05-25 Organon Nv Verfahren zur Herstellung eines Insulin-Praeparates

Also Published As

Publication number Publication date
JPH05503940A (ja) 1993-06-24
AU641991B2 (en) 1993-10-07
AU7337891A (en) 1991-09-18
PT96841A (pt) 1991-11-29
IE910579A1 (en) 1991-08-28
DK45590D0 (US07223432-20070529-C00017.png) 1990-02-21
WO1991012817A1 (en) 1991-09-05
ZA911279B (en) 1991-10-30
HU9202721D0 (en) 1992-12-28
EP0516704B1 (en) 1993-11-10
HUT63858A (en) 1993-10-28
DE69100626D1 (de) 1993-12-16
EP0516704A1 (en) 1992-12-09
NZ237176A (en) 1991-12-23

Similar Documents

Publication Publication Date Title
EP0516704B1 (en) Novel insulin compositions
DE3885317T2 (de) Makromolekulare Platin-Antitumorverbindungen.
US5456922A (en) Water dispersible and water soluble carbohydrate polymer compositions for parenteral administration of growth hormone
KR890004687B1 (ko) 생물학적 활성 서방출성 조성물
AU2004251625B2 (en) Synthesis of high molecular weight iron-saccharidic complexes
DE69815877T2 (de) Aggregate von menschlichen insulinderivaten
CA1094549A (en) Therapeutic insulin preparation and a process for the production of a stable insulin preparation with protracted effect
JPH01502434A (ja) 新規インシュリン誘導体
EP0646379A1 (en) Insulin formulation
IE61340B1 (en) Stable interferon complexes
HU227992B1 (en) Interferon conjugates, process for prepairing them, pharmaceutical compositions, containing them and use of them
CZ85790A3 (en) Novel preparations containing associates of hyaluronic acid, and process for preparing thereof
EP2496213B1 (en) Pharmaceutical solution of non covalently bound albumin and acylated insulin
EP2943216B1 (en) Modified ace2 polypeptides
JPH04504117A (ja) グリコシル化インシュリン
SA520420276B1 (ar) تركيبات صيدلية تحتوي على الأنسولين
JPH10511365A (ja) 遅延性ｇｌｐ−１組成物
EP0119650A2 (en) Galactosyl-insulin conjugates useful in treating diabetics
CA1335924C (en) Mixed crystals of insulin and insulin derivatives, a process for the preparation of these mixed crystals, pharmaceutical agents containing these mixed crystals, and the use thereof for the treatment of diabetes mellitus
Enriquez et al. Conjugation of adenine arabinoside 5'-monophosphate to arabinogalactan: synthesis, characterization, and antiviral activity
EP1308155B1 (en) Injectable solution containing a colloid of iron and shark cartilage-derived chondroitin sulfate
EP1620072B1 (en) Zinc-containing sustained-release composition, its preparation, and method for producing the same
JP2716497B2 (ja) ヘモグロビン コンプレツクス
EP2026789A2 (de) Neue, an der tumorphysiologie orientierte formulierung eines zytostatikums, insbesondere von cis-platin
DE2646223C2 (US07223432-20070529-C00017.png)

Legal Events

Date Code Title Description
FZDE Dead