CA2037009C - 15-dehydroxy-16-oxoprostaglandins - Google Patents

15-dehydroxy-16-oxoprostaglandins

Info

Publication number
CA2037009C
CA2037009C CA002037009A CA2037009A CA2037009C CA 2037009 C CA2037009 C CA 2037009C CA 002037009 A CA002037009 A CA 002037009A CA 2037009 A CA2037009 A CA 2037009A CA 2037009 C CA2037009 C CA 2037009C
Authority
CA
Canada
Prior art keywords
alkyl
compound
ion
oxo
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA002037009A
Other languages
English (en)
French (fr)
Other versions
CA2037009A1 (en
Inventor
Ryuji Ueno
Tomio Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sucampo GmbH
Original Assignee
Ueno Seiyaku Oyo Kenkyujo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ueno Seiyaku Oyo Kenkyujo KK filed Critical Ueno Seiyaku Oyo Kenkyujo KK
Publication of CA2037009A1 publication Critical patent/CA2037009A1/en
Application granted granted Critical
Publication of CA2037009C publication Critical patent/CA2037009C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002037009A 1990-02-26 1991-02-25 15-dehydroxy-16-oxoprostaglandins Expired - Lifetime CA2037009C (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP46932/1990 1990-02-26
JP4693290 1990-02-26
JP241938/1990 1990-09-11
JP24193890 1990-09-11

Publications (2)

Publication Number Publication Date
CA2037009A1 CA2037009A1 (en) 1991-08-27
CA2037009C true CA2037009C (en) 1998-01-27

Family

ID=26387096

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002037009A Expired - Lifetime CA2037009C (en) 1990-02-26 1991-02-25 15-dehydroxy-16-oxoprostaglandins

Country Status (10)

Country Link
EP (1) EP0444844B1 (OSRAM)
JP (1) JP2511579B2 (OSRAM)
KR (1) KR960008667B1 (OSRAM)
AT (1) ATE117290T1 (OSRAM)
AU (1) AU633697B2 (OSRAM)
CA (1) CA2037009C (OSRAM)
DE (1) DE69106744T2 (OSRAM)
DK (1) DK0444844T3 (OSRAM)
ES (1) ES2069821T3 (OSRAM)
TW (1) TW202430B (OSRAM)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221799A (en) * 1990-02-26 1993-06-22 K.K. Ueno Seiyaku Oyo Kenkyujo New 15-dehydroxy-16-oxoprostaglandins
WO1991013869A1 (fr) * 1990-03-08 1991-09-19 Shionogi & Co., Ltd. Derive de 15-desoxyprostaglandine
DE69124415T2 (de) * 1990-04-27 1997-05-15 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von 15-Dehydroxy-16-Oxoprostaglandin bei der Behandlung von allergischen Erkrankungen
US5302617A (en) * 1990-04-27 1994-04-12 Kabushikikaisha Ueno Seiyaku Oyo Kenkyuio Biochemical treatment with 15-dehydroxy-16-oxoprostaglandin compounds
US7321057B2 (en) * 2004-08-02 2008-01-22 R-Tech Ueno, Ltd. Method for manufacturing prostaglandin analogue
RU2440338C2 (ru) 2005-01-27 2012-01-20 Сукампо Аг Способ и композиция для лечения заболеваний центральной нервной системы

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4170709A (en) * 1977-10-03 1979-10-09 American Home Products Corporation 16-Keto PGE2 methyl esters
US4312994A (en) * 1981-03-25 1982-01-26 G. D. Searle & Co. α Chain dienic prostanoic acid derivatives
US4499296A (en) * 1983-11-14 1985-02-12 G. D. Searle & Co. Omega cycloalkyl prostaglandins
JPS60181068A (ja) * 1984-02-29 1985-09-14 Teijin Ltd ６−置換プロスタグランジンｅ↓１類およびその製造法

Also Published As

Publication number Publication date
DE69106744D1 (de) 1995-03-02
EP0444844A2 (en) 1991-09-04
EP0444844A3 (en) 1992-05-13
KR910021372A (ko) 1991-12-20
DE69106744T2 (de) 1995-05-18
TW202430B (OSRAM) 1993-03-21
EP0444844B1 (en) 1995-01-18
AU7139791A (en) 1991-08-29
ATE117290T1 (de) 1995-02-15
DK0444844T3 (da) 1995-04-03
AU633697B2 (en) 1993-02-04
JP2511579B2 (ja) 1996-06-26
CA2037009A1 (en) 1991-08-27
JPH04211053A (ja) 1992-08-03
ES2069821T3 (es) 1995-05-16
KR960008667B1 (ko) 1996-06-28

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed
MKEC Expiry (correction)

Effective date: 20121202