CA2028798A1 - Benzylpyrrolidine derivatives as dopamine agonists - Google Patents

Benzylpyrrolidine derivatives as dopamine agonists

Info

Publication number
CA2028798A1
CA2028798A1 CA002028798A CA2028798A CA2028798A1 CA 2028798 A1 CA2028798 A1 CA 2028798A1 CA 002028798 A CA002028798 A CA 002028798A CA 2028798 A CA2028798 A CA 2028798A CA 2028798 A1 CA2028798 A1 CA 2028798A1
Authority
CA
Canada
Prior art keywords
formula
compound
pharmaceutically acceptable
pyrrolidine
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002028798A
Other languages
English (en)
French (fr)
Inventor
Lawrence E. Fisher
Joan M. Caroon
Joseph M. Muchowski
Roberto P. Rosenkranz
Deborah L. Mcclelland
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of CA2028798A1 publication Critical patent/CA2028798A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
CA002028798A 1989-10-30 1990-10-29 Benzylpyrrolidine derivatives as dopamine agonists Abandoned CA2028798A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42857789A 1989-10-30 1989-10-30
US07/428,577 1989-10-30

Publications (1)

Publication Number Publication Date
CA2028798A1 true CA2028798A1 (en) 1991-05-01

Family

ID=23699508

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002028798A Abandoned CA2028798A1 (en) 1989-10-30 1990-10-29 Benzylpyrrolidine derivatives as dopamine agonists

Country Status (12)

Country Link
EP (1) EP0426075A1 (no)
JP (1) JPH03151358A (no)
KR (1) KR910007875A (no)
AU (1) AU636921B2 (no)
CA (1) CA2028798A1 (no)
FI (1) FI905325A0 (no)
HU (1) HUT55358A (no)
IE (1) IE903894A1 (no)
IL (1) IL96150A0 (no)
NO (1) NO904678L (no)
PT (1) PT95731A (no)
ZA (1) ZA908652B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995024390A1 (en) * 1994-03-11 1995-09-14 Smithkline Beecham Plc Novel phenyl(-alkyl/alkoxy)-1-aminoalkyl-substituted piperidines and pyrrolidines as calcium channel antagonists
DE202013103273U1 (de) 2013-07-22 2014-10-23 Wegener International Gmbh Biegemaschine zum Biegen von Werkstücken aus thermoplastischem Kunststoff

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1186660A (en) * 1968-09-11 1970-04-02 Parke Davis & Co New Pyrrolidine Compounds and Methods for their Production
ES8702355A1 (es) * 1981-07-22 1985-07-01 Syntex Inc Procedimiento para la preparacion de antidepresivos reguladores del sistema cardiovascular a base de pirrolidina sustituida
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
KR890012971A (ko) * 1988-02-10 1989-09-20 원본미기재 심장혈관 항히스타민제 및 분비억제제로서의 n-치환된-아릴알킬 및 아릴알킬렌 아미노헤테로사이클릭 화합물

Also Published As

Publication number Publication date
IE903894A1 (en) 1991-05-08
PT95731A (pt) 1991-09-13
NO904678D0 (no) 1990-10-29
ZA908652B (en) 1992-07-29
NO904678L (no) 1991-05-02
EP0426075A1 (en) 1991-05-08
JPH03151358A (ja) 1991-06-27
IL96150A0 (en) 1991-07-18
KR910007875A (ko) 1991-05-30
HUT55358A (en) 1991-05-28
AU6553490A (en) 1991-05-02
FI905325A0 (fi) 1990-10-29
AU636921B2 (en) 1993-05-13

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Legal Events

Date Code Title Description
FZDE Discontinued