CA2011428A1 - Utilisation de derives de 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine dans le traitement des psychoses et des inflammations et comme immunosuppresseur - Google Patents

Utilisation de derives de 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine dans le traitement des psychoses et des inflammations et comme immunosuppresseur

Info

Publication number
CA2011428A1
CA2011428A1 CA2011428A CA2011428A CA2011428A1 CA 2011428 A1 CA2011428 A1 CA 2011428A1 CA 2011428 A CA2011428 A CA 2011428A CA 2011428 A CA2011428 A CA 2011428A CA 2011428 A1 CA2011428 A1 CA 2011428A1
Authority
CA
Canada
Prior art keywords
tetrahydro
inflammation
phenyl
treatment
psychosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA2011428A
Other languages
English (en)
Other versions
CA2011428C (fr
Inventor
Billie Kenneth Koe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23244506&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2011428(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of CA2011428A1 publication Critical patent/CA2011428A1/fr
Application granted granted Critical
Publication of CA2011428C publication Critical patent/CA2011428C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002011428A 1989-03-07 1990-03-05 Utilisation de derives de 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine dans le traitement des psychoses et des inflammations et comme immunosuppresseur Expired - Fee Related CA2011428C (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/320,014 US4981870A (en) 1989-03-07 1989-03-07 Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants
US320,014 1989-03-07

Publications (2)

Publication Number Publication Date
CA2011428A1 true CA2011428A1 (fr) 1990-09-07
CA2011428C CA2011428C (fr) 1994-11-08

Family

ID=23244506

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002011428A Expired - Fee Related CA2011428C (fr) 1989-03-07 1990-03-05 Utilisation de derives de 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine dans le traitement des psychoses et des inflammations et comme immunosuppresseur

Country Status (17)

Country Link
US (2) US4981870A (fr)
EP (1) EP0386997B1 (fr)
JP (2) JPH0714870B2 (fr)
KR (1) KR920005810B1 (fr)
AT (1) ATE150299T1 (fr)
AU (1) AU610036B2 (fr)
CA (1) CA2011428C (fr)
DE (1) DE69030212T2 (fr)
DK (1) DK0386997T3 (fr)
HU (1) HU221624B1 (fr)
IE (1) IE81047B1 (fr)
IL (1) IL93576A (fr)
MY (1) MY106272A (fr)
NZ (1) NZ232800A (fr)
PH (1) PH26542A (fr)
PT (1) PT93351B (fr)
ZA (1) ZA901743B (fr)

Families Citing this family (50)

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US4981870A (en) * 1989-03-07 1991-01-01 Pfizer Inc. Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants
CA2071897A1 (fr) * 1989-12-28 1991-06-29 Richard A. Glennon Ligands du recepteur sigma et leur utilisation
ES2060547B1 (es) * 1992-06-04 1995-06-16 Ferrer Int Mejoras en el objeto de la patente de invencion n/ 9201158 que se refiere a "procedimiento de obtencion de nuevos derivados de la 4-bencilpiperidina".
WO1995000131A1 (fr) * 1993-06-23 1995-01-05 Cambridge Neuroscience, Incorporated Ligands du recepteur sigma et leur utilisation
ES2074946B1 (es) * 1993-07-19 1996-06-16 Ferrer Int Nuevos compuestos derivados de la 1,2-etanodiamina-n,n,n',n'-tetrasustituida.
AU739261B2 (en) 1997-07-01 2001-10-11 Pfizer Inc. Sertraline salts and sustained-release dosage forms of sertraline
US20040208926A1 (en) * 1997-07-01 2004-10-21 Pfizer Inc Solubilized sertraline compositions
US20030133974A1 (en) * 1997-07-01 2003-07-17 Curatolo William John Encapsulated solution dosage forms of sertraline
MXPA02006335A (es) 1999-12-23 2002-12-13 Pfizer Prod Inc Forma de dosificacion de farmaco en capas impulsada por hidrogel.
EP2147679B1 (fr) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions pour le transport de barrière hématoencéphalique
US6988556B2 (en) * 2002-02-19 2006-01-24 Halliburton Energy Services, Inc. Deep set safety valve
US8134029B2 (en) 2002-09-16 2012-03-13 Sunovion Pharmaceuticals Inc. Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine
AU2003272460B2 (en) * 2002-09-16 2009-12-17 Sepracor Inc. Treatment of CNS disorders with trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine and its formamide
US20040087661A1 (en) * 2002-09-16 2004-05-06 Sepracor, Inc. Treatment of CNS disorders with trans 4-3(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine
US20040220153A1 (en) * 2002-09-24 2004-11-04 Jost-Price Edward Roydon Methods and reagents for the treatment of diseases and disorders associated with increased levels of proinflammatory cytokines
CZ2006427A3 (cs) * 2003-12-29 2006-11-15 Sepracor Inc. Pyrrolové a pyrazolové inhibitory DAAO
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
CA2957667A1 (fr) * 2005-07-06 2007-01-11 Sepracor Inc. Combinaisons d'eszopiclone et de trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-n-methyl-1-naphtalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-naphtalenamine, et methodes de traitement de la menopause et des troubles de l'humeur, de l'anxiete et troubles cognitifs
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス，インコーポレイティド Ｐｄｅ阻害による神経新生の調節
CA2625210A1 (fr) 2005-10-31 2007-05-10 Braincells, Inc. Modulation de la neurogenese dont la mediation est assuree par recepteur gaba
AU2006335174B2 (en) * 2006-01-06 2012-09-06 Sunovion Pharmaceuticals Inc. Tetralone-based monoamine reuptake inhibitors
AU2007205114B2 (en) 2006-01-06 2012-11-08 Sunovion Pharmaceuticals Inc. Cycloalkylamines as monoamine reuptake inhibitors
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
AU2007233041B2 (en) 2006-03-31 2013-05-02 Sepracor Inc. Preparation of chiral amides and amines
AU2007249399A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
WO2007143267A2 (fr) * 2006-05-31 2007-12-13 Sepracor Inc. Traitement des troubles de type douleur par la trans-4-(3,4-dichlorophényl)-1,2,3,4-tétrahydro-1-naphtalénamine et son formamide
US7579370B2 (en) * 2006-06-30 2009-08-25 Sepracor Inc. Fused heterocycles
US7884124B2 (en) * 2006-06-30 2011-02-08 Sepracor Inc. Fluoro-substituted inhibitors of D-amino acid oxidase
KR20090064418A (ko) 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
WO2008036682A2 (fr) 2006-09-18 2008-03-27 Raptor Pharmaceutical Inc. Traitement des troubles hépatiques par l'administration de conjugués de protéine associée au récepteur (rap)
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080082066A1 (en) * 2006-10-02 2008-04-03 Weyerhaeuser Co. Crosslinked carboxyalkyl cellulose fibers having non-permanent and temporary crosslinks
FR2909376A1 (fr) * 2006-11-30 2008-06-06 Cerep Sa Procedes de preparation de la desmethulsertraline ou d'un de ses sels pharmaceutiquement acceptables
US7902252B2 (en) * 2007-01-18 2011-03-08 Sepracor, Inc. Inhibitors of D-amino acid oxidase
KR20090111322A (ko) * 2007-01-18 2009-10-26 세프라코 아이엔시. 디 아미노산 옥시다제의 억제제
EP3296289A3 (fr) 2007-05-31 2018-06-20 Sunovion Pharmaceuticals Inc. Cycloalkylamines substituées par un phényle en tant qu'inhibiteurs du recaptage de monoamines
US20100120740A1 (en) * 2008-08-07 2010-05-13 Sepracor Inc. Prodrugs of fused heterocyclic inhibitors of d-amino acid oxidase
WO2010099217A1 (fr) 2009-02-25 2010-09-02 Braincells, Inc. Modulation de neurogenèse à l'aide de combinaisons de d-cyclosérine
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them
WO2011017634A2 (fr) * 2009-08-07 2011-02-10 Sepracore Inc. Promédicaments d'inhibiteurs hétérocycliques fusionnés de la d-aminoacide oxydase
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2014144801A1 (fr) 2013-03-15 2014-09-18 Agenebio Inc. Procédés et compositions pour améliorer la fonction cognitive
WO2014144663A1 (fr) 2013-03-15 2014-09-18 The Johns Hopkins University Procédés et compositions pour améliorer la fonction cognitive
MX2016014780A (es) * 2014-05-13 2017-07-25 Sunovion Pharmaceuticals Inc Metodos y composiciones de dasotralina para el tratamiento del adhd.
WO2015175523A1 (fr) * 2014-05-13 2015-11-19 Sunovion Pharmaceuticals Inc. Dosage de dasotraline et méthode pour le traitement du tdah
WO2016046669A2 (fr) * 2014-09-27 2016-03-31 Mohan M Alapati Compositions et méthodes de traitement de la dépression et de maladies neurologiques
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
FR3071726B1 (fr) * 2017-09-29 2020-09-04 Univ Paris Sud Agents inhibant la proteine tctp pour le traitement de maladies proliferatives et de maladies infectieuses

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1420472A (en) * 1972-09-27 1976-01-07 Pfizer Aminophenyltetralin compounds
US4536518A (en) * 1979-11-01 1985-08-20 Pfizer Inc. Antidepressant derivatives of cis-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine
JPS59497B2 (ja) * 1979-11-01 1984-01-07 フアイザ−・インコ−ポレ−テツド トランス−４−フエニル−１，２，３，４−テトラヒドロ−１−ナフタレンアミンの抗抑うつ性誘導体
US4792448A (en) * 1987-06-11 1988-12-20 Pfizer Inc. Generic zero order controlled drug delivery system
US4981870A (en) * 1989-03-07 1991-01-01 Pfizer Inc. Use of 4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine derivatives in the treatment of psychosis, inflammation and as immunosuppressants

Also Published As

Publication number Publication date
HU221624B1 (hu) 2002-12-28
EP0386997A2 (fr) 1990-09-12
CA2011428C (fr) 1994-11-08
KR920005810B1 (ko) 1992-07-20
AU5079690A (en) 1990-09-20
PT93351B (pt) 1996-03-29
PT93351A (pt) 1990-11-07
HUT59000A (en) 1992-04-28
DE69030212D1 (de) 1997-04-24
NZ232800A (en) 1997-07-27
JPH0714870B2 (ja) 1995-02-22
JP3020808B2 (ja) 2000-03-15
IE81047B1 (en) 1999-12-01
ZA901743B (en) 1991-10-30
DE69030212T2 (de) 1997-06-26
EP0386997A3 (fr) 1992-04-29
IL93576A (en) 1995-12-08
ATE150299T1 (de) 1997-04-15
US4981870A (en) 1991-01-01
PH26542A (en) 1992-08-19
JPH07173056A (ja) 1995-07-11
JPH02300121A (ja) 1990-12-12
US5061728A (en) 1991-10-29
IE900798L (en) 1990-09-07
KR900013949A (ko) 1990-10-22
IL93576A0 (en) 1990-11-29
EP0386997B1 (fr) 1997-03-19
MY106272A (en) 1995-04-29
AU610036B2 (en) 1991-05-09
DK0386997T3 (da) 1997-04-14
HU901325D0 (en) 1990-05-28

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