CA1326017C - Ribofuranuronic acid derivatives - Google Patents

Ribofuranuronic acid derivatives

Info

Publication number
CA1326017C
CA1326017C CA000563261A CA563261A CA1326017C CA 1326017 C CA1326017 C CA 1326017C CA 000563261 A CA000563261 A CA 000563261A CA 563261 A CA563261 A CA 563261A CA 1326017 C CA1326017 C CA 1326017C
Authority
CA
Canada
Prior art keywords
desoxy
purinyl
beta
methyl
ribofuranuronic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA000563261A
Other languages
English (en)
French (fr)
Inventor
Fulvio Gadient
Arnold Vogel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Application granted granted Critical
Publication of CA1326017C publication Critical patent/CA1326017C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA000563261A 1987-04-06 1988-04-05 Ribofuranuronic acid derivatives Expired - Fee Related CA1326017C (en)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
DE3711562 1987-04-06
DEP3711561.8 1987-04-06
DE3711563 1987-04-06
DEP3711564.2 1987-04-06
DEP3711563.4 1987-04-06
DE3711561 1987-04-06
DE3711564 1987-04-06
DEP3711562.6 1987-04-06

Publications (1)

Publication Number Publication Date
CA1326017C true CA1326017C (en) 1994-01-11

Family

ID=27433888

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000563261A Expired - Fee Related CA1326017C (en) 1987-04-06 1988-04-05 Ribofuranuronic acid derivatives

Country Status (22)

Country Link
JP (1) JPS63258892A (pm)
KR (1) KR880012629A (pm)
AT (1) AT393507B (pm)
AU (1) AU609109B2 (pm)
BE (1) BE1002151A5 (pm)
CA (1) CA1326017C (pm)
CH (1) CH676121A5 (pm)
DK (1) DK183488A (pm)
ES (1) ES2007177A6 (pm)
FI (1) FI87463C (pm)
FR (1) FR2613367A1 (pm)
GB (1) GB2203149B (pm)
HU (1) HU201955B (pm)
IL (1) IL85969A (pm)
IT (1) IT1219892B (pm)
LU (1) LU87181A1 (pm)
MY (1) MY102323A (pm)
NL (1) NL8800862A (pm)
NZ (1) NZ224131A (pm)
PH (1) PH25424A (pm)
PT (1) PT87153B (pm)
SE (1) SE8801236A0 (pm)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4755594A (en) * 1986-01-31 1988-07-05 Warner-Lambert Company N6 -substituted adenosines
US5063233A (en) * 1986-11-14 1991-11-05 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists
US4954504A (en) * 1986-11-14 1990-09-04 Ciba-Geigy Corporation N9 -cyclopentyl-substituted adenine derivatives having adenosine-2 receptor stimulating activity
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
US4968697A (en) * 1987-02-04 1990-11-06 Ciba-Geigy Corporation 2-substituted adenosine 5'-carboxamides as antihypertensive agents
EP0277917A3 (en) * 1987-02-04 1990-03-28 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives
US5140015A (en) * 1990-02-20 1992-08-18 Whitby Research, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
USRE36494E (en) * 1990-02-20 2000-01-11 Discovery Therapeutics, Inc. 2-aralkoxy and 2-alkoxy adenosine derivatives as coronary vasodilators and antihypertensive agents
IT1254915B (it) * 1992-04-24 1995-10-11 Gloria Cristalli Derivati di adenosina ad attivita' a2 agonista
GB9301000D0 (en) * 1993-01-20 1993-03-10 Glaxo Group Ltd Chemical compounds
TW528755B (en) 1996-12-24 2003-04-21 Glaxo Group Ltd 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives
YU44900A (sh) 1998-01-31 2003-01-31 Glaxo Group Limited Derivati 2-(purin-9-il)tetrahidrofuran-3,4-diola
KR20010071591A (ko) 1998-06-23 2001-07-28 그레이엄 브레레톤, 레슬리 에드워즈 2-(퓨린-9-일)-테트라히드로푸란-3,4-디올 유도체
AR023463A1 (es) 1999-04-16 2002-09-04 Schering Corp Uso de compuestos de azetidinona
US20050033044A1 (en) 2003-05-19 2005-02-10 Bristol-Myers Squibb Pharma Company Methods for preparing 2-alkynyladenosine derivatives
AR049384A1 (es) 2004-05-24 2006-07-26 Glaxo Group Ltd Derivados de purina
JP5011112B2 (ja) * 2004-09-20 2012-08-29 イノテック ファーマシューティカルズ コーポレイション プリン誘導体を含有する炎症性疾患の治療用医薬
GB0514809D0 (en) 2005-07-19 2005-08-24 Glaxo Group Ltd Compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH606084A5 (en) * 1975-02-18 1978-10-13 Hoffmann La Roche (Di) nitrates of adenosine -5'-carboxylic acid derivs
US4167565A (en) * 1976-11-08 1979-09-11 Abbott Laboratories Adenosine-5'-carboxamides and method of use
DE3406533A1 (de) * 1984-02-23 1985-08-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
NL8702926A (nl) * 1986-12-15 1988-07-01 Sandoz Ag Nieuwe furanuronzuurderivaten en werkwijzen voor het bereiden en toepassen van deze derivaten.
EP0277917A3 (en) * 1987-02-04 1990-03-28 Ciba-Geigy Ag Certain adenosine 5'-carboxamide derivatives

Also Published As

Publication number Publication date
PT87153B (pt) 1992-07-31
GB8807750D0 (en) 1988-05-05
ES2007177A6 (es) 1989-06-01
SE8801236L (sv) 1988-10-17
LU87181A1 (fr) 1988-11-17
CH676121A5 (pm) 1990-12-14
FR2613367A1 (fr) 1988-10-07
KR880012629A (ko) 1988-11-28
ATA87388A (de) 1991-04-15
DK183488A (da) 1988-10-07
MY102323A (en) 1992-05-28
FI87463B (fi) 1992-09-30
NL8800862A (nl) 1988-11-01
DK183488D0 (da) 1988-04-05
IL85969A (en) 1992-03-29
AU1415188A (en) 1988-10-06
FI881571L (fi) 1988-10-07
SE8801236A0 (sv) 1988-10-17
JPS63258892A (ja) 1988-10-26
IT1219892B (it) 1990-05-24
IL85969A0 (en) 1988-09-30
AU609109B2 (en) 1991-04-26
AT393507B (de) 1991-11-11
FI881571A0 (fi) 1988-04-05
GB2203149A (en) 1988-10-12
BE1002151A5 (fr) 1990-08-07
NZ224131A (en) 1991-12-23
FI87463C (fi) 1993-01-11
HUT48902A (en) 1989-07-28
GB2203149B (en) 1991-02-13
IT8847794A0 (it) 1988-03-30
SE8801236D0 (sv) 1988-04-05
PT87153A (pt) 1988-05-01
HU201955B (en) 1991-01-28
PH25424A (pm) 1991-07-01

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Legal Events

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