CA1215048A - 2-(hexahydroazepino)-n-(2,6-dimethylphenyl)- acetamide, the hydrochloride thereof, a process for the preparation thereof and pharmaceutical compositions containing them - Google Patents

2-(hexahydroazepino)-n-(2,6-dimethylphenyl)- acetamide, the hydrochloride thereof, a process for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
CA1215048A
CA1215048A CA000432227A CA432227A CA1215048A CA 1215048 A CA1215048 A CA 1215048A CA 000432227 A CA000432227 A CA 000432227A CA 432227 A CA432227 A CA 432227A CA 1215048 A CA1215048 A CA 1215048A
Authority
CA
Canada
Prior art keywords
formula
acetamide
dimethylphenyl
hexahydroazepino
hydrochloride
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000432227A
Other languages
English (en)
French (fr)
Inventor
Alvaro Galiano Ramos
Alberto Stampa Diez Del Corral
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medichem SA
Original Assignee
Medichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medichem SA filed Critical Medichem SA
Application granted granted Critical
Publication of CA1215048A publication Critical patent/CA1215048A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000432227A 1982-07-14 1983-07-12 2-(hexahydroazepino)-n-(2,6-dimethylphenyl)- acetamide, the hydrochloride thereof, a process for the preparation thereof and pharmaceutical compositions containing them Expired CA1215048A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES513,980 1982-07-14
ES513980A ES8305724A1 (es) 1982-07-14 1982-07-14 Un procedimiento para la obtencion de la 2-(hexahidroazepin)-n-(2,6-dimetilfenil)acetamida.

Publications (1)

Publication Number Publication Date
CA1215048A true CA1215048A (en) 1986-12-09

Family

ID=8484458

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000432227A Expired CA1215048A (en) 1982-07-14 1983-07-12 2-(hexahydroazepino)-n-(2,6-dimethylphenyl)- acetamide, the hydrochloride thereof, a process for the preparation thereof and pharmaceutical compositions containing them

Country Status (10)

Country Link
JP (1) JPS5951272A (es)
BE (1) BE897281A (es)
CA (1) CA1215048A (es)
DE (1) DE3325004A1 (es)
ES (1) ES8305724A1 (es)
FR (1) FR2530244B1 (es)
GB (1) GB2124223B (es)
IT (1) IT1169538B (es)
NL (1) NL8302507A (es)
SE (1) SE8303862L (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8900685D0 (sv) * 1989-02-28 1989-02-28 Astra Ab New compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR907128A (fr) * 1943-07-15 1946-03-01 Astra Ab Procédé de préparation de produits d'anesthésie locale
DE963427C (de) * 1952-12-17 1957-05-09 Cassella Farbwerke Mainkur Ag Verfahren zur Herstellung neuer anaesthetisch wirkender Aminocarbonsaeureamide
HU183721B (en) * 1981-11-06 1984-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing new cyclic imine derivatives

Also Published As

Publication number Publication date
GB8319108D0 (en) 1983-08-17
ES513980A0 (es) 1983-04-16
IT8322053A1 (it) 1985-01-13
SE8303862L (sv) 1984-01-15
JPS5951272A (ja) 1984-03-24
IT8322053A0 (it) 1983-07-13
ES8305724A1 (es) 1983-04-16
FR2530244B1 (fr) 1986-10-31
BE897281A (fr) 1983-11-03
IT1169538B (it) 1987-06-03
GB2124223A (en) 1984-02-15
FR2530244A1 (fr) 1984-01-20
NL8302507A (nl) 1984-02-01
GB2124223B (en) 1985-09-04
DE3325004A1 (de) 1984-01-19
SE8303862D0 (sv) 1983-07-06

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